P01796 (HVM27_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Ig heavy chain V-III region A4
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	113 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous	This chain was isolated from a myeloma protein that binds inulin.
Sequence similarities	Contains 1 Ig-like (immunoglobulin-like) domain.

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain
PTM	Disulfide bond
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Molecular function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›113	›113	Ig heavy chain V-III region A4		PRO_0000059881
Regions
	Domain	1 – ›113	›113	Ig-like
Amino acid modifications
	Disulfide bond	22 ↔ 98		By similarity
Experimental info
	Non-terminal residue	113	1

Sequences

	Sequence		Length	Mass (Da)
	P01796 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 76658C121C598285	FASTA	113	12,675
	10 20 30 40 50 60 EVKLEESGGG LVQPGGSMKL SCVASGFTFS NYWMNWVRQS PEKGLEWVAE IRLKSHNYAT 70 80 90 100 110 HYAESVKGRF TISRDDSKSS VYLQMNNLRA EDTGIYYCTT GFAYWGQGTL VTV

References

[1]	"Sequence variation among heavy chains from inulin-binding myeloma proteins." Vrana M., Rudikoff S., Potter M. Proc. Natl. Acad. Sci. U.S.A. 75:1957-1961(1978) [PubMed: 417344] [Abstract] Cited for: PROTEIN SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
IPI	IPI00758135.
PIR	AVMSAB. A93818.
3D structure databases
ProteinModelPortal	P01796.
SMR	P01796. Positions 1-113.
ModBase	Search...
Protein-protein interaction databases
STRING	P01796.
Proteomic databases
PRIDE	P01796.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG018013.
Gene expression databases
Genevestigator	P01796.
GermOnline	ENSMUSG00000021155. Mus musculus.
Family and domain databases
InterPro	IPR007110. Ig-like. IPR013783. Ig-like_fold. IPR013106. Ig_V-set. IPR003596. Ig_V-set_subgr. [Graphical view]
Gene3D	G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
Pfam	PF07686. V-set. 1 hit. [Graphical view]
SMART	SM00406. IGv. 1 hit. [Graphical view]
PROSITE	PS50835. IG_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HVM27_MOUSE

Accession

Primary (citable) accession number: P01796

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	September 21, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program