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Protein

Ig heavy chain V region M603

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei33H-bond with the phosphate group of phosphorylcholine1
Sitei52H-bond with the phosphate group of phosphorylcholine1

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V region M603
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000598751 – ›122Ig heavy chain V region M603Add BLAST›122

Proteomic databases

MaxQBiP01789.
PRIDEiP01789.

Interactioni

Protein-protein interaction databases

MINTiMINT-1504974.

Structurei

Secondary structure

1122
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 7Combined sources5
Beta strandi10 – 12Combined sources3
Beta strandi18 – 27Combined sources10
Helixi29 – 31Combined sources3
Beta strandi34 – 39Combined sources6
Beta strandi41 – 43Combined sources3
Beta strandi46 – 51Combined sources6
Helixi54 – 56Combined sources3
Beta strandi60 – 62Combined sources3
Helixi64 – 66Combined sources3
Turni67 – 69Combined sources3
Beta strandi70 – 75Combined sources6
Turni76 – 79Combined sources4
Beta strandi80 – 85Combined sources6
Helixi90 – 92Combined sources3
Beta strandi94 – 101Combined sources8
Turni104 – 106Combined sources3
Beta strandi107 – 112Combined sources6
Beta strandi116 – 120Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MCPX-ray2.70H1-122[»]
2CJUX-ray2.50H1-121[»]
2MCPX-ray3.10H1-122[»]
ProteinModelPortaliP01789.
SMRiP01789.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01789.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 121Ig-likeAdd BLAST121

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region

Phylogenomic databases

HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P01789-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EVKLVESGGG LVQPGGSLRL SCATSGFTFS DFYMEWVRQP PGKRLEWIAA
60 70 80 90 100
SRNKGNKYTT EYSASVKGRF IVSRDTSQSI LYLQMNALRA EDTAIYYCAR
110 120
NYYGSTWYFD VWGAGTTVTV SS
Length:122
Mass (Da):13,626
Last modified:July 21, 1986 - v1
Checksum:iBA2C864438B64F0F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1221

Sequence databases

PIRiA30539.
A30556.
B30540.
B30556.
B90795. AVMS63.
D30556.
E30539.
H30539.
I30535.
PT0354.

Cross-referencesi

Sequence databases

PIRiA30539.
A30556.
B30540.
B30556.
B90795. AVMS63.
D30556.
E30539.
H30539.
I30535.
PT0354.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MCPX-ray2.70H1-122[»]
2CJUX-ray2.50H1-121[»]
2MCPX-ray3.10H1-122[»]
ProteinModelPortaliP01789.
SMRiP01789.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1504974.

Proteomic databases

MaxQBiP01789.
PRIDEiP01789.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG018013.

Miscellaneous databases

EvolutionaryTraceiP01789.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHVM20_MOUSE
AccessioniPrimary (citable) accession number: P01789
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 2, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This chain was isolated from a myeloma protein that binds phosphorylcholine.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.