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P01750 (HVM06_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified September 21, 2011. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ig heavy chain V region 102
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length117 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

This germline gene belongs to a set of closely related genes that could encode V regions of NPb antibodies.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919
Chain20 – 11798Ig heavy chain V region 102
PRO_0000015219

Regions

Region20 – 4930Framework-1
Region50 – 545Complementarity-determining-1
Region55 – 6814Framework-2
Region69 – 8517Complementarity-determining-2
Region86 – 11732Framework-3

Amino acid modifications

Disulfide bond41 ↔ 115 By similarity

Experimental info

Non-terminal residue1171

Secondary structure

1 ................... 117
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P01750 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 740A65DD851FCA8C

FASTA11712,867
        10         20         30         40         50         60 
MGWSCIILFL VATATGVHSH VQLQQPGAEL VKPGASVKVS CKASGYTFTS YWMHWVKQRP 

        70         80         90        100        110 
GQGLEWIGRI HPSDSDTNYN QKFKGKATLT VDKSSSTAYM QLSSLTSEDS AVYYCAI

« Hide

References

[1]"Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region."
Bothwell A.L.M., Paskind M., Reth M., Imanishi-Kari T., Rajewsky K., Baltimore D.
Cell 24:625-637(1981) [PubMed: 6788376] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6.
+Additional computationally mapped references.

Cross-references

Sequence databases

IPIIPI00108700.
PIRHVMS02. A02032.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1QNZNMR-H21-117[»]
ProteinModelPortalP01750.
SMRP01750. Positions 20-116.
ModBaseSearch...

Protein-protein interaction databases

STRINGP01750.

Proteomic databases

PRIDEP01750.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGroNOG16474.
GeneTreeENSGT00580000081342.
HOGENOMHBG716786.
HOVERGENHBG018013.
InParanoidP01750.
OrthoDBEOG4V6ZJ5.

Gene expression databases

GenevestigatorP01750.
GermOnlineENSMUSG00000072794. Mus musculus.

Family and domain databases

InterProIPR007110. Ig-like.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
Gene3DG3DSA:2.60.40.10. Ig-like_fold. 1 hit.
PfamPF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00406. IGv. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHVM06_MOUSE
AccessionPrimary (citable) accession number: P01750
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: September 21, 2011
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

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