ID   TVA1_MOUSE              Reviewed;         130 AA.
AC   P01738;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   13-SEP-2023, entry version 130.
DE   RecName: Full=T-cell receptor alpha chain V region PHDS58;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BALB.B;
RX   PubMed=6208487; DOI=10.1038/312036a0;
RA   Saito H., Kranz D.M., Takagaki Y., Hayday A.C., Eisen H.N., Tonegawa S.;
RT   "A third rearranged and expressed gene in a clone of cytotoxic T
RT   lymphocytes.";
RL   Nature 312:36-40(1984).
CC   -!- MISCELLANEOUS: This clone was isolated from a cytotoxic T lymphocyte.
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DR   PIR; A02012; RWMS58.
DR   PDB; 1G6R; X-ray; 2.80 A; A/C=21-130.
DR   PDB; 1I9E; X-ray; 2.50 A; A=21-130.
DR   PDB; 1MWA; X-ray; 2.40 A; A/C=21-130.
DR   PDB; 1TCR; X-ray; 2.50 A; A=21-130.
DR   PDB; 2CKB; X-ray; 3.00 A; A/C=21-130.
DR   PDB; 2ICW; X-ray; 2.41 A; I/K=21-130.
DR   PDB; 2OI9; X-ray; 2.35 A; B=21-130.
DR   PDB; 3E2H; X-ray; 3.80 A; B=22-130.
DR   PDB; 3E3Q; X-ray; 2.95 A; C/D/I/M/R/V/Z/d=22-130.
DR   PDB; 4MVB; X-ray; 3.09 A; A=20-129.
DR   PDB; 4MXQ; X-ray; 2.60 A; C=20-113.
DR   PDB; 4N0C; X-ray; 2.90 A; C/G=20-129.
DR   PDB; 4N5E; X-ray; 3.06 A; C=20-113.
DR   PDB; 4NHU; X-ray; 2.90 A; A/C=21-130.
DR   PDBsum; 1G6R; -.
DR   PDBsum; 1I9E; -.
DR   PDBsum; 1MWA; -.
DR   PDBsum; 1TCR; -.
DR   PDBsum; 2CKB; -.
DR   PDBsum; 2ICW; -.
DR   PDBsum; 2OI9; -.
DR   PDBsum; 3E2H; -.
DR   PDBsum; 3E3Q; -.
DR   PDBsum; 4MVB; -.
DR   PDBsum; 4MXQ; -.
DR   PDBsum; 4N0C; -.
DR   PDBsum; 4N5E; -.
DR   PDBsum; 4NHU; -.
DR   AlphaFoldDB; P01738; -.
DR   SMR; P01738; -.
DR   MINT; P01738; -.
DR   GlyGen; P01738; 1 site.
DR   InParanoid; P01738; -.
DR   EvolutionaryTrace; P01738; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01738; Protein.
DR   GO; GO:0042101; C:T cell receptor complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   CDD; cd04983; IgV_TCR_alpha; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   PANTHER; PTHR19367:SF5; T CELL RECEPTOR ALPHA VARIABLE 8-3; 1.
DR   PANTHER; PTHR19367; T-CELL RECEPTOR ALPHA CHAIN V REGION; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Glycoprotein; Immunity;
KW   Immunoglobulin domain; Receptor; Reference proteome; Signal;
KW   T cell receptor.
FT   SIGNAL          1..20
FT   CHAIN           21..130
FT                   /note="T-cell receptor alpha chain V region PHDS58"
FT                   /id="PRO_0000033591"
FT   REGION          21..114
FT                   /note="V segment"
FT   REGION          115..130
FT                   /note="J segment"
FT   CARBOHYD        90
FT                   /note="N-linked (GlcNAc...) asparagine"
FT   NON_TER         130
FT   STRAND          22..24
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          28..33
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          38..40
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          43..45
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          52..57
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          59..61
FT                   /evidence="ECO:0007829|PDB:2CKB"
FT   STRAND          64..69
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          74..77
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   HELIX           79..81
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          82..87
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   TURN            88..91
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          92..99
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   HELIX           102..104
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          106..113
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   HELIX           115..117
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          119..121
FT                   /evidence="ECO:0007829|PDB:2OI9"
FT   STRAND          125..130
FT                   /evidence="ECO:0007829|PDB:2OI9"
SQ   SEQUENCE   130 AA;  14320 MW;  19E638A8EEBFA635 CRC64;
     MLLALLPVLG IHFVLRDAQA QSVTQPDARV TVSEGASLQL RCKYSYSATP YLFWYVQYPR
     QGLQLLLKYY SGDPVVQGVN GFEAEFSKSN SSFHLRKASV HWSDSAVYFC AVSGFASALT
     FGSGTKVIVL
//