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Protein

Ig lambda-1 chain V region

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-983695. Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.

Names & Taxonomyi

Protein namesi
Recommended name:
Ig lambda-1 chain V region
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Add BLAST20
ChainiPRO_000001520121 – 117Ig lambda-1 chain V regionAdd BLAST97

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei21Pyrrolidone carboxylic acidBy similarity1

Keywords - PTMi

Pyrrolidone carboxylic acid

Proteomic databases

MaxQBiP01723.
PRIDEiP01723.

Interactioni

Protein-protein interaction databases

IntActiP01723. 1 interactor.

Structurei

Secondary structure

1117
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi24 – 26Combined sources3
Beta strandi28 – 32Combined sources5
Beta strandi38 – 47Combined sources10
Helixi51 – 53Combined sources3
Beta strandi56 – 61Combined sources6
Turni62 – 64Combined sources3
Beta strandi65 – 71Combined sources7
Turni72 – 74Combined sources3
Beta strandi84 – 89Combined sources6
Beta strandi92 – 99Combined sources8
Helixi102 – 104Combined sources3
Beta strandi106 – 113Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1P4BX-ray2.35L22-117[»]
1P4IX-ray2.80L22-117[»]
1Q0XX-ray1.60L22-117[»]
1SM3X-ray1.95L23-117[»]
ProteinModelPortaliP01723.
SMRiP01723.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01723.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – ›117Ig-likeAdd BLAST›97

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01723-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAWISLILSL LALSSGGAIS QAVVTQESAL TTSPGETVTL TCRSSTGAVT
60 70 80 90 100
TSNYANWVQE KPDHLFTGLI GGTNNRAPGV PARFSGSLIG DKAALTITGA
110
QTEDEAIYFC ALWYSNH
Length:117
Mass (Da):12,222
Last modified:July 19, 2004 - v2
Checksum:i36F3C5601C54B55A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1171

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00811 Genomic DNA. Translation: CAA24193.1.
PIRiA01994. L1MSV.
PH1090.
UniGeneiMm.326349.
Mm.456234.
Mm.469795.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00811 Genomic DNA. Translation: CAA24193.1.
PIRiA01994. L1MSV.
PH1090.
UniGeneiMm.326349.
Mm.456234.
Mm.469795.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1P4BX-ray2.35L22-117[»]
1P4IX-ray2.80L22-117[»]
1Q0XX-ray1.60L22-117[»]
1SM3X-ray1.95L23-117[»]
ProteinModelPortaliP01723.
SMRiP01723.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP01723. 1 interactor.

Protein family/group databases

IMGTiSearch...

Proteomic databases

MaxQBiP01723.
PRIDEiP01723.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG018013.

Enzyme and pathway databases

ReactomeiR-MMU-983695. Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.

Miscellaneous databases

EvolutionaryTraceiP01723.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLV1A_MOUSE
AccessioniPrimary (citable) accession number: P01723
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 19, 2004
Last modified: November 2, 2016
This is version 123 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.