Reviewed, UniProtKB/Swiss-Prot P01723 (LV1A_MOUSE)

Names and origin

Protein names	Recommended name:     Ig lambda-1 chain V region
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	117 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Contains 1 Ig-like (immunoglobulin-like) domain.

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain Signal
Technical term	3D-structure
Gene Ontology (GO)
Molecular function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
	P01820	1	EBI-1037949,EBI-1027999

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20
	Chain	21 – 117	97	Ig lambda-1 chain V region		PRO_0000015201
Regions
	Domain	21 – ›117	›97	Ig-like
Experimental info
	Non-terminal residue	117	1

Sequences

	Sequence		Length	Mass (Da)
	P01723-1 [UniParc]. Last modified July 19, 2004. Version 2. Checksum: 36F3C5601C54B55A	FASTA	117	12,222
	10 20 30 40 50 60 MAWISLILSL LALSSGGAIS QAVVTQESAL TTSPGETVTL TCRSSTGAVT TSNYANWVQE 70 80 90 100 110 KPDHLFTGLI GGTNNRAPGV PARFSGSLIG DKAALTITGA QTEDEAIYFC ALWYSNH

References

[1]	"Sequences of mouse immunoglobulin light chain genes before and after somatic changes." Bernard O., Hozumi N., Tonegawa S. Cell 15:1133-1144(1978) [PubMed: 103630] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

V00811 Genomic DNA. Translation: CAA24193.1.

IPI

IPI00406023.

PIR

L1MSV. A01994.
PH1090.

UniGene

Mm.326349
Mm.456234
Mm.469795

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1P4B	X-ray	2.35	L	22-117	[»]
1P4I	X-ray	2.80	L	22-117	[»]
1Q0X	X-ray	1.60	L	22-113	[»]

ModBase

Search...

Protein-protein interaction databases

IntAct

P01723. 1 interaction.

Protein family/group databases

IMGT

Search...

Genome annotation databases

Ensembl

ENSMUSG00000076934. Mus musculus. [Contig view]

Phylogenomic databases

HOVERGEN

P01723.

Gene expression databases

Bgee

P01723.

GermOnline

ENSMUSG00000061944. Mus musculus.

Family and domain databases

InterPro

IPR007110. Ig-like.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_sub.
[Graphical view]

Gene3D

G3DSA:2.60.40.10. Ig-like_fold. 1 hit.

Pfam

PF07686. V-set. 1 hit.
[Graphical view]

SMART

SM00406. IGv. 1 hit.
[Graphical view]

PROSITE

PS50835. IG_LIKE. 1 hit.
[Graphical view]

ProtoNet

Search...

Other Resources

BindingDB

P01723.

Entry information

Entry name

LV1A_MOUSE

Accession

Primary (citable) accession number: P01723

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 19, 2004
Last modified:	May 26, 2009
This is version 73 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)