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Protein

Ig kappa chain V-III region PC 7043

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-III region PC 7043
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›111›111Ig kappa chain V-III region PC 7043PRO_0000059787Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi23 ↔ 92PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Interactioni

Protein-protein interaction databases

MINTiMINT-225960.

Structurei

Secondary structure

1
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 74Combined sources
Beta strandi9 – 146Combined sources
Beta strandi19 – 213Combined sources
Beta strandi23 – 275Combined sources
Beta strandi37 – 426Combined sources
Beta strandi49 – 535Combined sources
Turni54 – 563Combined sources
Beta strandi77 – 815Combined sources
Helixi84 – 863Combined sources
Beta strandi88 – 947Combined sources
Beta strandi96 – 994Combined sources
Beta strandi106 – 1116Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1QNZNMR-L1-111[»]
2ZCHX-ray2.83L1-111[»]
2ZCKX-ray3.10L1-111[»]
2ZCLX-ray3.25L1-111[»]
ProteinModelPortaliP01665.
SMRiP01665. Positions 1-111.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01665.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 2323Framework-1Add
BLAST
Regioni24 – 3815Complementarity-determining-1Add
BLAST
Regioni39 – 5315Framework-2Add
BLAST
Regioni54 – 607Complementarity-determining-2
Regioni61 – 9232Framework-3Add
BLAST
Regioni93 – 1019Complementarity-determining-3
Regioni102 – 11110Framework-4

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region

Phylogenomic databases

HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P01665-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DIVLTQSPAS LAVSLGQRAT ISCKASQSVD YDGDSYMNWY QQKPGQPPKL
60 70 80 90 100
LIYAASNLES GIPARFSGSG SGTDFTLNIH PVEEEDAATY YCQQSNEDPF
110
TFGSGTKLEI K
Length:111
Mass (Da):12,002
Last modified:July 21, 1986 - v1
Checksum:i7A5FCB586C306D29
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei111 – 1111

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z25444 mRNA. Translation: CAA80931.1.
Z25446 mRNA. Translation: CAA80933.1.
Z25448 mRNA. Translation: CAA80935.1.
Z25450 mRNA. Translation: CAA80937.1.
Z25452 mRNA. Translation: CAA80939.1.
Z25454 mRNA. Translation: CAA80941.1.
Z25458 mRNA. Translation: CAA80945.1.
PIRiA01937. KVMS43.
UniGeneiMm.333124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z25444 mRNA. Translation: CAA80931.1.
Z25446 mRNA. Translation: CAA80933.1.
Z25448 mRNA. Translation: CAA80935.1.
Z25450 mRNA. Translation: CAA80937.1.
Z25452 mRNA. Translation: CAA80939.1.
Z25454 mRNA. Translation: CAA80941.1.
Z25458 mRNA. Translation: CAA80945.1.
PIRiA01937. KVMS43.
UniGeneiMm.333124.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1QNZNMR-L1-111[»]
2ZCHX-ray2.83L1-111[»]
2ZCKX-ray3.10L1-111[»]
2ZCLX-ray3.25L1-111[»]
ProteinModelPortaliP01665.
SMRiP01665. Positions 1-111.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-225960.

Protein family/group databases

IMGTiSearch...
Search...
Search...
Search...
Search...
Search...
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG018013.

Miscellaneous databases

EvolutionaryTraceiP01665.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Rearrangement of genetic information may produce immunoglobulin diversity."
    Weigert M., Gatmaitan L., Loh E., Schilling J., Hood L.E.
    Nature 276:785-790(1978) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
  2. "Variable region gene selection of immunoglobulin G-expressing B cells with specificity for a defined epitope on type II collagen."
    Mo J.A., Bona C.A., Holmdahl R.
    Eur. J. Immunol. 23:2503-2510(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 10-99.
  3. "NMR structure of an anti-gp120 antibody complex with a V3 peptide reveals a surface important for co-receptor binding."
    Tugarinov V., Zvi A., Levy R., Hayek Y., Matsushita S., Anglister J.
    Structure 8:385-395(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 1-111.

Entry informationi

Entry nameiKV3AD_MOUSE
AccessioniPrimary (citable) accession number: P01665
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.