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P01661

- KV3A9_MOUSE

UniProt

P01661 - KV3A9_MOUSE

Protein

Ig kappa chain V-III region MOPC 63

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. antigen binding Source: UniProtKB-KW

    Protein family/group databases

    MEROPSiI43.001.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ig kappa chain V-III region MOPC 63
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 20201 PublicationAdd
    BLAST
    Chaini21 – 131111Ig kappa chain V-III region MOPC 63PRO_0000015187Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi43 ↔ 112PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    PRIDEiP01661.

    Expressioni

    Gene expression databases

    GenevestigatoriP01661.

    Structurei

    Secondary structure

    1
    131
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi24 – 274
    Beta strandi29 – 313
    Beta strandi39 – 479
    Beta strandi57 – 626
    Beta strandi68 – 736
    Turni74 – 763
    Beta strandi86 – 905
    Beta strandi92 – 10110
    Beta strandi108 – 1147
    Beta strandi116 – 1194
    Beta strandi126 – 1283

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1EGJX-ray2.80L21-131[»]
    ProteinModelPortaliP01661.
    SMRiP01661. Positions 22-131.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP01661.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 4323Framework-1Add
    BLAST
    Regioni44 – 5815Complementarity-determining-1Add
    BLAST
    Regioni59 – 7315Framework-2Add
    BLAST
    Regioni74 – 807Complementarity-determining-2
    Regioni81 – 11232Framework-3Add
    BLAST
    Regioni113 – 1219Complementarity-determining-3
    Regioni122 – 13110Framework-4

    Keywords - Domaini

    Immunoglobulin domain, Immunoglobulin V region, Signal

    Phylogenomic databases

    eggNOGiNOG76434.
    HOGENOMiHOG000059537.
    HOVERGENiHBG018013.
    InParanoidiP01661.
    PhylomeDBiP01661.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view]
    PfamiPF07686. V-set. 1 hit.
    [Graphical view]
    SMARTiSM00406. IGv. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P01661-1 [UniParc]FASTAAdd to Basket

    « Hide

    METDTLLLWV LLLWVPGSTG NIVLTQSPAS LAVSLGQRAT ISCRASESVD    50
    SYGNSFMHWY QQKPGQPPKL LIYLASNLES GVPARFSGSG SRTDFTLTID 100
    PVEADDAATY YCQQNNEDPW TFGGGTKLEI K 131
    Length:131
    Mass (Da):14,291
    Last modified:July 21, 1986 - v1
    Checksum:iD212EC9F08DC880A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei131 – 1311

    Sequence databases

    PIRiB90412. KVMSM6.
    D45722.

    Cross-referencesi

    Sequence databases

    PIRi B90412. KVMSM6.
    D45722.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1EGJ X-ray 2.80 L 21-131 [» ]
    ProteinModelPortali P01661.
    SMRi P01661. Positions 22-131.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi I43.001.

    Proteomic databases

    PRIDEi P01661.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG76434.
    HOGENOMi HOG000059537.
    HOVERGENi HBG018013.
    InParanoidi P01661.
    PhylomeDBi P01661.

    Miscellaneous databases

    EvolutionaryTracei P01661.

    Gene expression databases

    Genevestigatori P01661.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view ]
    Pfami PF07686. V-set. 1 hit.
    [Graphical view ]
    SMARTi SM00406. IGv. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes."
      Burstein Y., Schechter I.
      Biochemistry 17:2392-2400(1978) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-35.
    2. "Mouse immunoglobulin chains. Pattern of sequence variation among kappa chains with limited sequence differences."
      McKean D.J., Potter M., Hood L.E.
      Biochemistry 12:760-771(1973) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 21-131.
    3. "Mechanisms of antibody diversity: multiple genes encode structurally related mouse kappa variable regions."
      McKean D.J., Bell M., Potter M.
      Proc. Natl. Acad. Sci. U.S.A. 75:3913-3917(1978) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION.

    Entry informationi

    Entry nameiKV3A9_MOUSE
    AccessioniPrimary (citable) accession number: P01661
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: July 21, 1986
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3