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P01661

- KV3A9_MOUSE

UniProt

P01661 - KV3A9_MOUSE

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Protein

Ig kappa chain V-III region MOPC 63

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. antigen binding Source: UniProtKB-KW
Complete GO annotation...

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-III region MOPC 63
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 20201 PublicationAdd
BLAST
Chaini21 – 131111Ig kappa chain V-III region MOPC 63PRO_0000015187Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi43 ↔ 112PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP01661.

Expressioni

Gene expression databases

GenevestigatoriP01661.

Structurei

Secondary structure

1
131
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi24 – 274Combined sources
Beta strandi29 – 313Combined sources
Beta strandi39 – 479Combined sources
Beta strandi57 – 626Combined sources
Beta strandi68 – 736Combined sources
Turni74 – 763Combined sources
Beta strandi86 – 905Combined sources
Beta strandi92 – 10110Combined sources
Beta strandi108 – 1147Combined sources
Beta strandi116 – 1194Combined sources
Beta strandi126 – 1283Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1EGJX-ray2.80L21-131[»]
ProteinModelPortaliP01661.
SMRiP01661. Positions 22-131.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01661.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 4323Framework-1Add
BLAST
Regioni44 – 5815Complementarity-determining-1Add
BLAST
Regioni59 – 7315Framework-2Add
BLAST
Regioni74 – 807Complementarity-determining-2
Regioni81 – 11232Framework-3Add
BLAST
Regioni113 – 1219Complementarity-determining-3
Regioni122 – 13110Framework-4

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

eggNOGiNOG76434.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
PhylomeDBiP01661.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01661-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
METDTLLLWV LLLWVPGSTG NIVLTQSPAS LAVSLGQRAT ISCRASESVD
60 70 80 90 100
SYGNSFMHWY QQKPGQPPKL LIYLASNLES GVPARFSGSG SRTDFTLTID
110 120 130
PVEADDAATY YCQQNNEDPW TFGGGTKLEI K
Length:131
Mass (Da):14,291
Last modified:July 21, 1986 - v1
Checksum:iD212EC9F08DC880A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei131 – 1311

Sequence databases

PIRiB90412. KVMSM6.
D45722.

Cross-referencesi

Sequence databases

PIRi B90412. KVMSM6.
D45722.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1EGJ X-ray 2.80 L 21-131 [» ]
ProteinModelPortali P01661.
SMRi P01661. Positions 22-131.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I43.001.

Proteomic databases

PRIDEi P01661.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi NOG76434.
HOGENOMi HOG000059537.
HOVERGENi HBG018013.
PhylomeDBi P01661.

Miscellaneous databases

EvolutionaryTracei P01661.

Gene expression databases

Genevestigatori P01661.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view ]
Pfami PF07686. V-set. 1 hit.
[Graphical view ]
SMARTi SM00406. IGv. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes."
    Burstein Y., Schechter I.
    Biochemistry 17:2392-2400(1978) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-35.
  2. "Mouse immunoglobulin chains. Pattern of sequence variation among kappa chains with limited sequence differences."
    McKean D.J., Potter M., Hood L.E.
    Biochemistry 12:760-771(1973) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 21-131.
  3. "Mechanisms of antibody diversity: multiple genes encode structurally related mouse kappa variable regions."
    McKean D.J., Bell M., Potter M.
    Proc. Natl. Acad. Sci. U.S.A. 75:3913-3917(1978) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.

Entry informationi

Entry nameiKV3A9_MOUSE
AccessioniPrimary (citable) accession number: P01661
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 26, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3