P01659 (KV3A7_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Ig kappa chain V-III region TEPC 124
Organism	Mus musculus (Mouse) [Reference proteome]
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	112 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain
PTM	Disulfide bond
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Molecular_function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›112	›112	Ig kappa chain V-III region TEPC 124		PRO_0000059782
Regions
	Region	1 – 23	23	Framework-1
	Region	24 – 38	15	Complementarity-determining-1
	Region	39 – 53	15	Framework-2
	Region	54 – 60	7	Complementarity-determining-2
	Region	61 – 92	32	Framework-3
	Region	93 – 101	9	Complementarity-determining-3
	Region	102 – 111	10	Framework-4
Amino acid modifications
	Disulfide bond	23 ↔ 92		By similarity
Experimental info
	Non-terminal residue	112	1

Sequences

	Sequence		Length	Mass (Da)
	P01659 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 7CFD328DBE8E9D71	FASTA	112	12,340
	10 20 30 40 50 60 DIVLTQSPAS LAVSLGQRAT ISCRASZSVN WYGNSFMZWY ZZKPGZPPKL LIYRASNLZS 70 80 90 100 110 GIPARFSGSG SRTBFTLTIB PVZABDVATY FCZZSBZAPW TFGSGTKLEI KR

References

[1]	"Mouse immunoglobulin chains. Pattern of sequence variation among kappa chains with limited sequence differences." McKean D.J., Potter M., Hood L.E. Biochemistry 12:760-771(1973) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases
IPI	IPI00464397.
3D structure databases
ProteinModelPortal	P01659.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG018013.
Gene expression databases
Genevestigator	P01659.
Family and domain databases
Gene3D	2.60.40.10. 1 hit.
InterPro	IPR007110. Ig-like_dom. IPR013783. Ig-like_fold. IPR013106. Ig_V-set. IPR003596. Ig_V-set_subgr. [Graphical view]
Pfam	PF07686. V-set. 1 hit. [Graphical view]
SMART	SM00406. IGv. 1 hit. [Graphical view]
PROSITE	PS50835. IG_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35563467.

Entry information

Entry name

KV3A7_MOUSE

Accession

Primary (citable) accession number: P01659

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	April 3, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program