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P01647

- KV5AE_MOUSE

UniProt

P01647 - KV5AE_MOUSE

Protein

Ig kappa chain V-V region HP 124E1

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. antigen binding Source: UniProtKB-KW

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ig kappa chain V-V region HP 124E1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – ›108›108Ig kappa chain V-V region HP 124E1PRO_0000059802Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi23 ↔ 88PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    PRIDEiP01647.

    Expressioni

    Gene expression databases

    GenevestigatoriP01647.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1511096.

    Structurei

    Secondary structure

    1
    108
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi9 – 135
    Beta strandi19 – 279
    Beta strandi33 – 386
    Beta strandi44 – 496
    Turni50 – 523
    Beta strandi62 – 676
    Beta strandi70 – 778
    Helixi80 – 823
    Beta strandi84 – 907
    Beta strandi92 – 954
    Beta strandi102 – 1065

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1EZVX-ray2.30Y10-107[»]
    2V7HX-ray2.80A/L1-108[»]
    2VWEX-ray3.40C/J1-108[»]
    3U0WX-ray2.00L1-108[»]
    ProteinModelPortaliP01647.
    SMRiP01647. Positions 1-108.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP01647.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni1 – 2323Framework-1Add
    BLAST
    Regioni24 – 3411Complementarity-determining-1Add
    BLAST
    Regioni35 – 4915Framework-2Add
    BLAST
    Regioni50 – 567Complementarity-determining-2
    Regioni57 – 8832Framework-3Add
    BLAST
    Regioni89 – 979Complementarity-determining-3
    Regioni98 – 10811Framework-4Add
    BLAST

    Keywords - Domaini

    Immunoglobulin domain, Immunoglobulin V region

    Phylogenomic databases

    HOVERGENiHBG018013.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view]
    PfamiPF07686. V-set. 1 hit.
    [Graphical view]
    SMARTiSM00406. IGv. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P01647-1 [UniParc]FASTAAdd to Basket

    « Hide

    DIQMTQTTSS LSASLGDRVT ISCRASQDIN NYLNWYQQKP DGTVKLLIYY    50
    TSRLHSGVPS RFSGSGSGTD YSLTISNLEQ EDIATYFCQQ GKTLPRTFGG 100
    GTKLEIKR 108
    Length:108
    Mass (Da):11,965
    Last modified:July 21, 1986 - v1
    Checksum:i39971BC653EFEFA2
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei108 – 1081

    Sequence databases

    PIRiA28044.
    B26405.
    B28044.
    C26405.
    D48677.

    Cross-referencesi

    Sequence databases

    PIRi A28044.
    B26405.
    B28044.
    C26405.
    D48677.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1EZV X-ray 2.30 Y 10-107 [» ]
    2V7H X-ray 2.80 A/L 1-108 [» ]
    2VWE X-ray 3.40 C/J 1-108 [» ]
    3U0W X-ray 2.00 L 1-108 [» ]
    ProteinModelPortali P01647.
    SMRi P01647. Positions 1-108.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1511096.

    Proteomic databases

    PRIDEi P01647.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG018013.

    Miscellaneous databases

    EvolutionaryTracei P01647.
    NextBioi 35563460.

    Gene expression databases

    Genevestigatori P01647.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view ]
    Pfami PF07686. V-set. 1 hit.
    [Graphical view ]
    SMARTi SM00406. IGv. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete amino acid sequence of light chain variable regions derived from five monoclonal anti-p-azophenylarsonate antibodies differing with respect to a crossreactive idiotype."
      Siegelman M., Capra J.D.
      Proc. Natl. Acad. Sci. U.S.A. 78:7679-7683(1981) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Strain: A/J.

    Entry informationi

    Entry nameiKV5AE_MOUSE
    AccessioniPrimary (citable) accession number: P01647
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: July 21, 1986
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Anti-arsonate hybridoma protein.

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3