P01645 (KV5AC_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Ig kappa chain V-V region HP 93G7
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous

Anti-arsonate hybridoma protein.

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain
PTM	Disulfide bond
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Molecular function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – ›108

›108

Ig kappa chain V-V region HP 93G7

PRO_0000059800

Regions

Region

1 – 23

23

Framework-1

Region

24 – 34

11

Complementarity-determining-1

Region

35 – 49

15

Framework-2

Region

50 – 56

7

Complementarity-determining-2

Region

57 – 88

32

Framework-3

Region

89 – 97

9

Complementarity-determining-3

Region

98 – 108

11

Framework-4

Amino acid modifications

Disulfide bond

23 ↔ 88

By similarity

Experimental info

Non-terminal residue

108

1

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

108

Helix Strand Turn

Details...

Beta strand

5 – 7

3

Beta strand

19 – 27

9

Beta strand

33 – 38

6

Beta strand

44 – 49

6

Turn

50 – 52

3

Beta strand

62 – 67

6

Beta strand

70 – 77

8

Helix

80 – 82

3

Beta strand

84 – 90

7

Beta strand

92 – 95

4

Beta strand

97 – 99

3

Sequences

	Sequence		Length	Mass (Da)
	P01645 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 22F4642C63EFF58E	FASTA	108	11,954
	10 20 30 40 50 60 DIQMTQTTSS LSASLGDRVT ISCRASQDIS NYLNWYQQKP DGTVKLLIYY TSRLHSGVPS 70 80 90 100 RFSGSGSGTD YSLTISNLEQ EDIATYFCQQ GNMLPRTFGG GTKLEIKR

References

[1]	"Complete amino acid sequence of light chain variable regions derived from five monoclonal anti-p-azophenylarsonate antibodies differing with respect to a crossreactive idiotype." Siegelman M., Capra J.D. Proc. Natl. Acad. Sci. U.S.A. 78:7679-7683(1981) [PubMed: 6801658] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: A/J.
+	Additional computationally mapped references.

Cross-references

Sequence databases

IPI

IPI00138019.

PIR

A28044.
B26405.
B28044.
B49026.
C26405.
D48677.
PL0282.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1A14	X-ray	2.50	L	5-102	[»]

ProteinModelPortal

P01645.

SMR

P01645. Positions 1-108.

ModBase

Search...

Protein-protein interaction databases

STRING

P01645.

Proteomic databases

PRIDE

P01645.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Phylogenomic databases

HOVERGEN

HBG018013.

Gene expression databases

Genevestigator

P01645.

Family and domain databases

InterPro

IPR007110. Ig-like.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]

Gene3D

G3DSA:2.60.40.10. Ig-like_fold. 1 hit.

Pfam

PF07686. V-set. 1 hit.
[Graphical view]

SMART

SM00406. IGv. 1 hit.
[Graphical view]

PROSITE

PS50835. IG_LIKE. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

KV5AC_MOUSE

Accession

Primary (citable) accession number: P01645

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	September 21, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program