Reviewed, UniProtKB/Swiss-Prot P01645 (KV5AC_MOUSE)

Names and origin

Protein names	Recommended name:     Ig kappa chain V-V region HP 93G7
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous

Anti-arsonate hybridoma protein.

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain
PTM	Disulfide bond
Technical term	3D-structure Direct protein sequencing
Gene Ontology (GO)
Molecular function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – ›108

›108

Ig kappa chain V-V region HP 93G7

PRO_0000059800

Regions

Region

1 – 23

23

Framework-1

Region

24 – 34

11

Complementarity-determining-1

Region

35 – 49

15

Framework-2

Region

50 – 56

7

Complementarity-determining-2

Region

57 – 88

32

Framework-3

Region

89 – 97

9

Complementarity-determining-3

Region

98 – 108

11

Framework-4

Amino acid modifications

Disulfide bond

23 ↔ 88

By similarity

Experimental info

Non-terminal residue

108

1

Secondary structure

1

.

.

.

.

.

.

.

.

.

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.

.

.

.

.

.

.

108

Helix Strand Turn

Details...

Beta strand

5 – 7

3

Beta strand

19 – 27

9

Beta strand

33 – 38

6

Beta strand

44 – 49

6

Turn

50 – 52

3

Beta strand

62 – 67

6

Beta strand

70 – 77

8

Helix

80 – 82

3

Beta strand

84 – 90

7

Beta strand

92 – 95

4

Beta strand

97 – 99

3

Sequences

	Sequence		Length	Mass (Da)
	P01645-1 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 22F4642C63EFF58E	FASTA	108	11,954
	10 20 30 40 50 60 DIQMTQTTSS LSASLGDRVT ISCRASQDIS NYLNWYQQKP DGTVKLLIYY TSRLHSGVPS 70 80 90 100 RFSGSGSGTD YSLTISNLEQ EDIATYFCQQ GNMLPRTFGG GTKLEIKR

References

[1]	"Complete amino acid sequence of light chain variable regions derived from five monoclonal anti-p-azophenylarsonate antibodies differing with respect to a crossreactive idiotype." Siegelman M., Capra J.D. Proc. Natl. Acad. Sci. U.S.A. 78:7679-7683(1981) [PubMed: 6801658] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: A/J.
+	Additional computationally mapped references.

Cross-references

Sequence databases

IPI

IPI00138019.

PIR

A28044.
B26405.
B28044.
B49026.
C26405.
D48677.
PL0282.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1A14	X-ray	2.50	L	5-102	[»]

SMR

P01645. Positions 1-108.

ModBase

Search...

Protein-protein interaction databases

STRING

P01645.

Proteomic databases

PRIDE

P01645.

Phylogenomic databases

HOVERGEN

P01645.

Gene expression databases

Genevestigator

P01645.

Family and domain databases

InterPro

IPR007110. Ig-like.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_sub.
[Graphical view]

Gene3D

G3DSA:2.60.40.10. Ig-like_fold. 1 hit.

Pfam

PF07686. V-set. 1 hit.
[Graphical view]

SMART

SM00406. IGv. 1 hit.
[Graphical view]

PROSITE

PS50835. IG_LIKE. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

KV5AC_MOUSE

Accession

Primary (citable) accession number: P01645

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	October 13, 2009
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)