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P01642

- KV5A9_MOUSE

UniProt

P01642 - KV5A9_MOUSE

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Protein

Ig kappa chain V-V region L7

Gene
Gm10881
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. antigen binding Source: UniProtKB-KW
Complete GO annotation...

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-V region L7
Gene namesi
Name:Gm10881
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:3642817. Gm10881.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Add
BLAST
Chaini21 – ›115›95Ig kappa chain V-V region L7PRO_0000015196Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi43 ↔ 108 By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP01642.

Expressioni

Gene expression databases

BgeeiP01642.
GenevestigatoriP01642.

Structurei

Secondary structure

1
115
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi24 – 274
Beta strandi29 – 335
Beta strandi39 – 479
Beta strandi53 – 586
Beta strandi65 – 695
Turni70 – 723
Beta strandi82 – 876
Beta strandi90 – 978
Helixi100 – 1023
Beta strandi104 – 1107
Beta strandi112 – 1154

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1C08X-ray2.30A21-115[»]
1IC4X-ray2.50L21-115[»]
1IC5X-ray2.30L21-115[»]
1IC7X-ray2.10L21-115[»]
1J1OX-ray1.80L21-115[»]
1J1PX-ray1.80L21-115[»]
1J1XX-ray1.80L21-115[»]
2OZ4X-ray2.70L21-115[»]
4CKDelectron microscopy13.00L/M/N/O21-115[»]
ProteinModelPortaliP01642.
SMRiP01642. Positions 21-115.

Miscellaneous databases

EvolutionaryTraceiP01642.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 4323Framework-1Add
BLAST
Regioni44 – 5411Complementarity-determining-1Add
BLAST
Regioni55 – 6915Framework-2Add
BLAST
Regioni70 – 767Complementarity-determining-2
Regioni77 – 10832Framework-3Add
BLAST
Regioni109 – ›115›7Complementarity-determining-3

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

eggNOGiNOG270118.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
InParanoidiP01642.
OMAiTKTSSAW.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01642-1 [UniParc]FASTAAdd to Basket

« Hide

MVSTPQFLVF LLFWIPASRG DILLTQSPAI LSVSPGERVS FSCRASQSIG    50
TSIHWYQQRT NGSPRLLIKY ASESISGIPS RFSGSGSGTD FTLSINSVES 100
EDIADYYCQQ SNSWP 115
Length:115
Mass (Da):12,615
Last modified:July 21, 1986 - v1
Checksum:iC17BEC758C577E00
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei115 – 1151

Sequence databases

PIRiA01925. KVMSL7.

Genome annotation databases

EnsembliENSMUST00000103364; ENSMUSP00000100165; ENSMUSG00000076563.

Cross-referencesi

Sequence databases

PIRi A01925. KVMSL7.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1C08 X-ray 2.30 A 21-115 [» ]
1IC4 X-ray 2.50 L 21-115 [» ]
1IC5 X-ray 2.30 L 21-115 [» ]
1IC7 X-ray 2.10 L 21-115 [» ]
1J1O X-ray 1.80 L 21-115 [» ]
1J1P X-ray 1.80 L 21-115 [» ]
1J1X X-ray 1.80 L 21-115 [» ]
2OZ4 X-ray 2.70 L 21-115 [» ]
4CKD electron microscopy 13.00 L/M/N/O 21-115 [» ]
ProteinModelPortali P01642.
SMRi P01642. Positions 21-115.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I43.001.

Proteomic databases

PRIDEi P01642.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000103364 ; ENSMUSP00000100165 ; ENSMUSG00000076563 .

Organism-specific databases

MGIi MGI:3642817. Gm10881.

Phylogenomic databases

eggNOGi NOG270118.
HOGENOMi HOG000059537.
HOVERGENi HBG018013.
InParanoidi P01642.
OMAi TKTSSAW.

Miscellaneous databases

EvolutionaryTracei P01642.
SOURCEi Search...

Gene expression databases

Bgeei P01642.
Genevestigatori P01642.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view ]
Pfami PF07686. V-set. 1 hit.
[Graphical view ]
SMARTi SM00406. IGv. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism."
    Pech M., Hochtl J., Schnell H., Zachau H.G.
    Nature 291:668-670(1981) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiKV5A9_MOUSE
AccessioniPrimary (citable) accession number: P01642
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: June 11, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

There appears to be two possible splice junctions at the 3' end of the intron. The alternate would code for a protein lacking residues 17-19.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3

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