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Protein

Ig kappa chain V-V region L7

Gene

Gm10881

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-V region L7
Gene namesi
Name:Gm10881
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:3642817. Gm10881.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Add BLAST20
ChainiPRO_000001519621 – ›115Ig kappa chain V-V region L7Add BLAST›95

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 108PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP01642.
PeptideAtlasiP01642.
PRIDEiP01642.

Expressioni

Gene expression databases

BgeeiENSMUSG00000076563.

Structurei

Secondary structure

1115
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi24 – 27Combined sources4
Beta strandi29 – 33Combined sources5
Beta strandi39 – 47Combined sources9
Beta strandi53 – 58Combined sources6
Beta strandi65 – 69Combined sources5
Turni70 – 72Combined sources3
Beta strandi82 – 87Combined sources6
Beta strandi90 – 97Combined sources8
Helixi100 – 102Combined sources3
Beta strandi104 – 110Combined sources7
Beta strandi112 – 115Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1C08X-ray2.30A21-115[»]
1IC4X-ray2.50L21-115[»]
1IC5X-ray2.30L21-115[»]
1IC7X-ray2.10L21-115[»]
1J1OX-ray1.80L21-115[»]
1J1PX-ray1.80L21-115[»]
1J1XX-ray1.80L21-115[»]
2OZ4X-ray2.70L21-115[»]
4CKDelectron microscopy13.00L/M/N/O21-115[»]
ProteinModelPortaliP01642.
SMRiP01642.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01642.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 43Framework-1Add BLAST23
Regioni44 – 54Complementarity-determining-1Add BLAST11
Regioni55 – 69Framework-2Add BLAST15
Regioni70 – 76Complementarity-determining-27
Regioni77 – 108Framework-3Add BLAST32
Regioni109 – ›115Complementarity-determining-3›7

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

GeneTreeiENSGT00780000121852.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
InParanoidiP01642.
OMAiTKTSSAW.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00408. IGc2. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01642-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSTPQFLVF LLFWIPASRG DILLTQSPAI LSVSPGERVS FSCRASQSIG
60 70 80 90 100
TSIHWYQQRT NGSPRLLIKY ASESISGIPS RFSGSGSGTD FTLSINSVES
110
EDIADYYCQQ SNSWP
Length:115
Mass (Da):12,615
Last modified:July 21, 1986 - v1
Checksum:iC17BEC758C577E00
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1151

Sequence databases

PIRiA01925. KVMSL7.

Genome annotation databases

EnsembliENSMUST00000103364; ENSMUSP00000100165; ENSMUSG00000076563.

Cross-referencesi

Sequence databases

PIRiA01925. KVMSL7.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1C08X-ray2.30A21-115[»]
1IC4X-ray2.50L21-115[»]
1IC5X-ray2.30L21-115[»]
1IC7X-ray2.10L21-115[»]
1J1OX-ray1.80L21-115[»]
1J1PX-ray1.80L21-115[»]
1J1XX-ray1.80L21-115[»]
2OZ4X-ray2.70L21-115[»]
4CKDelectron microscopy13.00L/M/N/O21-115[»]
ProteinModelPortaliP01642.
SMRiP01642.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiP01642.
PeptideAtlasiP01642.
PRIDEiP01642.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000103364; ENSMUSP00000100165; ENSMUSG00000076563.

Organism-specific databases

MGIiMGI:3642817. Gm10881.

Phylogenomic databases

GeneTreeiENSGT00780000121852.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
InParanoidiP01642.
OMAiTKTSSAW.

Miscellaneous databases

EvolutionaryTraceiP01642.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000076563.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00408. IGc2. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKV5A9_MOUSE
AccessioniPrimary (citable) accession number: P01642
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 2, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

There appears to be two possible splice junctions at the 3' end of the intron. The alternate would code for a protein lacking residues 17-19.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.