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P01642 (KV5A9_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ig kappa chain V-V region L7
Gene names
Name:Gm10881
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length115 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

There appears to be two possible splice junctions at the 3' end of the intron. The alternate would code for a protein lacking residues 17-19.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020
Chain21 – ›115›95Ig kappa chain V-V region L7
PRO_0000015196

Regions

Region21 – 4323Framework-1
Region44 – 5411Complementarity-determining-1
Region55 – 6915Framework-2
Region70 – 767Complementarity-determining-2
Region77 – 10832Framework-3
Region109 – ›115›7Complementarity-determining-3

Amino acid modifications

Disulfide bond43 ↔ 108 By similarity

Experimental info

Non-terminal residue1151

Secondary structure

1 ..................... 115
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P01642 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: C17BEC758C577E00

FASTA11512,615
        10         20         30         40         50         60 
MVSTPQFLVF LLFWIPASRG DILLTQSPAI LSVSPGERVS FSCRASQSIG TSIHWYQQRT 

        70         80         90        100        110 
NGSPRLLIKY ASESISGIPS RFSGSGSGTD FTLSINSVES EDIADYYCQQ SNSWP

« Hide

References

[1]"Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism."
Pech M., Hochtl J., Schnell H., Zachau H.G.
Nature 291:668-670(1981) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

IPIIPI00663560.
PIRKVMSL7. A01925.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1C08X-ray2.30A21-115[»]
1IC4X-ray2.50L21-115[»]
1IC5X-ray2.30L21-115[»]
1IC7X-ray2.10L21-115[»]
1J1OX-ray1.80L21-115[»]
1J1PX-ray1.80L21-115[»]
1J1XX-ray1.80L21-115[»]
2OZ4X-ray2.70L21-115[»]
ProteinModelPortalP01642.
SMRP01642. Positions 21-115.
ModBaseSearch...

Protein family/group databases

MEROPSI43.001.

Proteomic databases

PRIDEP01642.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:3642817. Gm10881.

Phylogenomic databases

eggNOGNOG270118.
HOGENOMHOG000059537.
HOVERGENHBG018013.
InParanoidP01642.
OMATSIHWYQ.
OrthoDBEOG4ZW5CP.

Gene expression databases

BgeeP01642.
GenevestigatorP01642.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamPF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00406. IGv. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP01642.
SOURCESearch...

Entry information

Entry nameKV5A9_MOUSE
AccessionPrimary (citable) accession number: P01642
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: April 3, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

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