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Reviewed, UniProtKB/Swiss-Prot P01642 (KV5A9_MOUSE)

Last modified January 19, 2010. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Ig kappa chain V-V region L7
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length115 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Miscellaneous

There appears to be two possible splice junctions at the 3' end of the intron. The alternate would code for a protein lacking residues 17-19.

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Ontologies

Keywords
   DomainImmunoglobulin V region
Immunoglobulin domain
Signal
   PTMDisulfide bond
   Technical term3D-structure
Gene Ontology (GO)
   Molecular functionantigen binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020
Chain21 – ›115›95Ig kappa chain V-V region L7
PRO_0000015196

Regions

Region21 – 4323Framework-1
Region44 – 5411Complementarity-determining-1
Region55 – 6915Framework-2
Region70 – 767Complementarity-determining-2
Region77 – 10832Framework-3
Region109 – ›115›7Complementarity-determining-3

Amino acid modifications

Disulfide bond43 ↔ 108 By similarity

Experimental info

Non-terminal residue1151

Secondary structure

1 .................... 115
Helix Strand Turn

Details...

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Sequences

Sequence LengthMass (Da)Tools
P01642-1 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: C17BEC758C577E00

FASTA11512,615
        10         20         30         40         50         60 
MVSTPQFLVF LLFWIPASRG DILLTQSPAI LSVSPGERVS FSCRASQSIG TSIHWYQQRT 

        70         80         90        100        110 
NGSPRLLIKY ASESISGIPS RFSGSGSGTD FTLSINSVES EDIADYYCQQ SNSWP

« Hide

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References

[1]"Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism."
Pech M., Hochtl J., Schnell H., Zachau H.G.
Nature 291:668-670(1981) [PubMed: 6264318] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

IPIIPI00663560.
PIRKVMSL7. A01925.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1C08X-ray2.30A21-115[»]
1IC4X-ray2.50L21-115[»]
1IC5X-ray2.30L21-115[»]
1IC7X-ray2.10L21-115[»]
1J1OX-ray1.80L21-115[»]
1J1PX-ray1.80L21-115[»]
1J1XX-ray1.80L21-115[»]
2OZ4X-ray2.70L21-115[»]
ModBaseSearch...

Genome annotation databases

EnsemblENSMUST00000103364; ENSMUSP00000100165; ENSMUSG00000076563; Mus musculus. [Genome view]

Organism-specific databases

MGIMGI:3642817. ENSMUSG00000029975.

Phylogenomic databases

eggNOGroNOG17332.
HOGENOMHBG716786.
HOVERGENP01642.
InParanoidP01642.
OMAIGSSLHW.
PhylomeDBP01642.

Gene expression databases

BgeeP01642.
GenevestigatorP01642.

Family and domain databases

InterProIPR007110. Ig-like.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_sub.
[Graphical view]
Gene3DG3DSA:2.60.40.10. Ig-like_fold. 1 hit.
PfamPF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00406. IGv. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameKV5A9_MOUSE
AccessionPrimary (citable) accession number: P01642
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: January 19, 2010
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

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Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents