ID   KV5A8_MOUSE             Reviewed;         117 AA.
AC   P01641;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   27-MAR-2024, entry version 132.
DE   RecName: Full=Ig kappa chain V-V region MOPC 173B;
DE   Flags: Precursor;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6777049; DOI=10.1016/0092-8674(80)90442-0;
RA   Max E.E., Seidman J.G., Miller H., Leder P.;
RT   "Variation in the crossover point of kappa immunoglobulin gene V-J
RT   recombination: evidence from a cryptic gene.";
RL   Cell 21:793-799(1980).
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DR   EMBL; K00880; AAA39031.1; -; Genomic_DNA.
DR   PIR; A01924; KVMS3B.
DR   AlphaFoldDB; P01641; -.
DR   SMR; P01641; -.
DR   PeptideAtlas; P01641; -.
DR   Ensembl; ENSMUST00000200578.5; ENSMUSP00000142382.2; ENSMUSG00000093906.6.
DR   AGR; MGI:3525017; -.
DR   VEuPathDB; HostDB:ENSMUSG00000093906; -.
DR   GeneTree; ENSGT00940000153924; -.
DR   InParanoid; P01641; -.
DR   OMA; RCAFELT; -.
DR   PhylomeDB; P01641; -.
DR   Proteomes; UP000000589; Chromosome 6.
DR   RNAct; P01641; Protein.
DR   Bgee; ENSMUSG00000093906; Expressed in mesodermal cell in embryo and 19 other cell types or tissues.
DR   ExpressionAtlas; P01641; baseline and differential.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   PANTHER; PTHR23267:SF216; IG KAPPA CHAIN V-V REGION HP 123E6-RELATED; 1.
DR   PANTHER; PTHR23267; IMMUNOGLOBULIN LIGHT CHAIN; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
PE   4: Predicted;
KW   Adaptive immunity; Disulfide bond; Immunity; Immunoglobulin;
KW   Reference proteome; Signal.
FT   SIGNAL          1..22
FT   CHAIN           23..117
FT                   /note="Ig kappa chain V-V region MOPC 173B"
FT                   /id="PRO_0000015195"
FT   REGION          23..45
FT                   /note="Framework-1"
FT   REGION          46..56
FT                   /note="Complementarity-determining-1"
FT   REGION          57..71
FT                   /note="Framework-2"
FT   REGION          72..78
FT                   /note="Complementarity-determining-2"
FT   REGION          79..110
FT                   /note="Framework-3"
FT   REGION          111..>117
FT                   /note="Complementarity-determining-3"
FT   DISULFID        45..110
FT                   /evidence="ECO:0000250"
FT   NON_TER         117
SQ   SEQUENCE   117 AA;  12955 MW;  24B3D4B9AC2E4D6C CRC64;
     MDMRAPAQVF GFLLLWFPGA RCDIQMTQSP SSLSASLGER VSLTCRASQD IHGYLNLFQQ
     KPGETIKHLI YETSNLDSGV PKRFSGSRSG SDYSLIIGSL ESEDFADYYC LQYASSP
//