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Protein

Ig kappa chain V-V region MOPC 173B

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. antigen binding Source: UniProtKB-KW
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-V region MOPC 173B
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Add
BLAST
Chaini23 – 11795Ig kappa chain V-V region MOPC 173BPRO_0000015195Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi45 ↔ 110By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP01641.

Expressioni

Gene expression databases

GenevestigatoriP01641.

Structurei

3D structure databases

ProteinModelPortaliP01641.
SMRiP01641. Positions 24-117.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni23 – 4523Framework-1Add
BLAST
Regioni46 – 5611Complementarity-determining-1Add
BLAST
Regioni57 – 7115Framework-2Add
BLAST
Regioni72 – 787Complementarity-determining-2
Regioni79 – 11032Framework-3Add
BLAST
Regioni111 – ›117›7Complementarity-determining-3

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

eggNOGiNOG137595.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
PhylomeDBiP01641.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01641-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMRAPAQVF GFLLLWFPGA RCDIQMTQSP SSLSASLGER VSLTCRASQD
60 70 80 90 100
IHGYLNLFQQ KPGETIKHLI YETSNLDSGV PKRFSGSRSG SDYSLIIGSL
110
ESEDFADYYC LQYASSP
Length:117
Mass (Da):12,955
Last modified:July 21, 1986 - v1
Checksum:i24B3D4B9AC2E4D6C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei117 – 1171

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K00880 Genomic DNA. Translation: AAA39031.1.
PIRiA01924. KVMS3B.
UniGeneiMm.370329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K00880 Genomic DNA. Translation: AAA39031.1.
PIRiA01924. KVMS3B.
UniGeneiMm.370329.

3D structure databases

ProteinModelPortaliP01641.
SMRiP01641. Positions 24-117.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

IMGTiSearch...

Proteomic databases

PRIDEiP01641.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiNOG137595.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
PhylomeDBiP01641.

Gene expression databases

GenevestigatoriP01641.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene."
    Max E.E., Seidman J.G., Miller H., Leder P.
    Cell 21:793-799(1980) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiKV5A8_MOUSE
AccessioniPrimary (citable) accession number: P01641
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: January 7, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.