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Protein

Ig kappa chain V-V region MOPC 173B

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-V region MOPC 173B
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Add
BLAST
Chaini23 – 11795Ig kappa chain V-V region MOPC 173BPRO_0000015195Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi45 ↔ 110By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP01641.

Expressioni

Gene expression databases

ExpressionAtlasiP01641. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliP01641.
SMRiP01641. Positions 24-117.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni23 – 4523Framework-1Add
BLAST
Regioni46 – 5611Complementarity-determining-1Add
BLAST
Regioni57 – 7115Framework-2Add
BLAST
Regioni72 – 787Complementarity-determining-2
Regioni79 – 11032Framework-3Add
BLAST
Regioni111 – ›117›7Complementarity-determining-3

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

HOGENOMiHOG000059537.
HOVERGENiHBG018013.
OMAiRASQDIH.
PhylomeDBiP01641.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01641-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMRAPAQVF GFLLLWFPGA RCDIQMTQSP SSLSASLGER VSLTCRASQD
60 70 80 90 100
IHGYLNLFQQ KPGETIKHLI YETSNLDSGV PKRFSGSRSG SDYSLIIGSL
110
ESEDFADYYC LQYASSP
Length:117
Mass (Da):12,955
Last modified:July 21, 1986 - v1
Checksum:i24B3D4B9AC2E4D6C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei117 – 1171

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K00880 Genomic DNA. Translation: AAA39031.1.
PIRiA01924. KVMS3B.
UniGeneiMm.370329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K00880 Genomic DNA. Translation: AAA39031.1.
PIRiA01924. KVMS3B.
UniGeneiMm.370329.

3D structure databases

ProteinModelPortaliP01641.
SMRiP01641. Positions 24-117.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

IMGTiSearch...

Proteomic databases

PRIDEiP01641.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000059537.
HOVERGENiHBG018013.
OMAiRASQDIH.
PhylomeDBiP01641.

Gene expression databases

ExpressionAtlasiP01641. baseline and differential.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene."
    Max E.E., Seidman J.G., Miller H., Leder P.
    Cell 21:793-799(1980) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiKV5A8_MOUSE
AccessioniPrimary (citable) accession number: P01641
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: March 16, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.