Reviewed, UniProtKB/Swiss-Prot P01637 (KV5A5_MOUSE)

Names and origin

Protein names	Recommended name:     Ig kappa chain V-V region T1
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	128 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain Signal
PTM	Disulfide bond
Gene Ontology (GO)
Molecular function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20
	Chain	21 – 128	108	Ig kappa chain V-V region T1		PRO_0000015192
Regions
	Region	21 – 43	23	Framework-1
	Region	44 – 54	11	Complementarity-determining-1
	Region	55 – 69	15	Framework-2
	Region	70 – 76	7	Complementarity-determining-2
	Region	77 – 108	32	Framework-3
	Region	109 – 117	9	Complementarity-determining-3
	Region	118 – 127	10	Framework-4
Amino acid modifications
	Disulfide bond	43 ↔ 108		By similarity
Experimental info
	Non-terminal residue	128	1

Sequences

	Sequence		Length	Mass (Da)
	P01637-1 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: AFA5563D31BB7E05	FASTA	128	14,386
	10 20 30 40 50 60 MRTPAQFLGI LLLWFPGIKC DIKMTQSPSS MYASLGERVT ISCKASQDIN SYLTWFQQKP 70 80 90 100 110 120 GKSPKTLLYR ANRLVDGVPS RFSGSGSGQD FSLTISSLEY EDMGIYYCLQ YDEFPLTFGA GTKLELKR

References

[1]	"Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma." Altenburger W., Steinmetz M., Zachau H.G. Nature 287:603-607(1980) [PubMed: 6776411] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	V00772 Genomic DNA. Translation: CAA24150.1.
IPI	IPI00464381.
PIR	KVMST1. A01920.
3D structure databases
HSSP	HSSP built from PDB template 1WTL based on UniProtKB P80362.
SMR	P01637. Positions 21-128.
ModBase	Search...
Protein-protein interaction databases
STRING	P01637.
Protein family/group databases
IMGT	Search...
Proteomic databases
PRIDE	P01637.
Genome annotation databases
Ensembl	ENSMUST00000103320; ENSMUSP00000100121; ENSMUSG00000076519; Mus musculus. [Genome view]
Phylogenomic databases
HOVERGEN	P01637.
Gene expression databases
ArrayExpress	P01637.
Bgee	P01637.
Genevestigator	P01637.
GermOnline	ENSMUSG00000061260. Mus musculus.
Family and domain databases
InterPro	IPR007110. Ig-like. IPR013783. Ig-like_fold. IPR013106. Ig_V-set. IPR003596. Ig_V-set_sub. [Graphical view]
Gene3D	G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
Pfam	PF07686. V-set. 1 hit. [Graphical view]
SMART	SM00406. IGv. 1 hit. [Graphical view]
PROSITE	PS50835. IG_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KV5A5_MOUSE

Accession

Primary (citable) accession number: P01637

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	October 13, 2009
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)