P01637 (KV5A5_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Ig kappa chain V-V region T1
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	128 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Immunoglobulin V region Immunoglobulin domain Signal
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	antigen binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20
	Chain	21 – 128	108	Ig kappa chain V-V region T1		PRO_0000015192
Regions
	Region	21 – 43	23	Framework-1
	Region	44 – 54	11	Complementarity-determining-1
	Region	55 – 69	15	Framework-2
	Region	70 – 76	7	Complementarity-determining-2
	Region	77 – 108	32	Framework-3
	Region	109 – 117	9	Complementarity-determining-3
	Region	118 – 127	10	Framework-4
Amino acid modifications
	Disulfide bond	43 ↔ 108		By similarity
Experimental info
	Non-terminal residue	128	1

Sequences

	Sequence		Length	Mass (Da)
	P01637 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: AFA5563D31BB7E05	FASTA	128	14,386
	10 20 30 40 50 60 MRTPAQFLGI LLLWFPGIKC DIKMTQSPSS MYASLGERVT ISCKASQDIN SYLTWFQQKP 70 80 90 100 110 120 GKSPKTLLYR ANRLVDGVPS RFSGSGSGQD FSLTISSLEY EDMGIYYCLQ YDEFPLTFGA GTKLELKR

References

[1]	"Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma." Altenburger W., Steinmetz M., Zachau H.G. Nature 287:603-607(1980) [PubMed: 6776411] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	V00772 Genomic DNA. Translation: CAA24150.1.
IPI	IPI00464381.
PIR	KVMST1. A01920.
3D structure databases
ProteinModelPortal	P01637.
SMR	P01637. Positions 21-128.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-120812.
STRING	P01637.
Protein family/group databases
IMGT	Search...
Proteomic databases
PRIDE	P01637.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	roNOG17437.
HOVERGEN	HBG018013.
InParanoid	P01637.
OrthoDB	EOG4CG09R.
Gene expression databases
ArrayExpress	P01637.
Bgee	P01637.
Genevestigator	P01637.
GermOnline	ENSMUSG00000061260. Mus musculus.
Family and domain databases
InterPro	IPR007110. Ig-like. IPR013783. Ig-like_fold. IPR013106. Ig_V-set. IPR003596. Ig_V-set_subgr. [Graphical view]
Gene3D	G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
Pfam	PF07686. V-set. 1 hit. [Graphical view]
SMART	SM00406. IGv. 1 hit. [Graphical view]
PROSITE	PS50835. IG_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KV5A5_MOUSE

Accession

Primary (citable) accession number: P01637

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	September 21, 2011
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program