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P01635 (KV5A3_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ig kappa chain V-V region K2
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length115 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

The gene was isolated and sequenced separately from two different sources, embryos and cultured plasmacytoma cells that secrete the similar kappa chain MOPC 149.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020
Chain21 – ›115›95Ig kappa chain V-V region K2
PRO_0000015191

Regions

Region21 – 4323Framework-1
Region44 – 5411Complementarity-determining-1
Region55 – 6915Framework-2
Region70 – 767Complementarity-determining-2
Region77 – 10832Framework-3
Region109 – ›115›7Complementarity-determining-3

Amino acid modifications

Disulfide bond43 ↔ 108 By similarity

Experimental info

Non-terminal residue1151

Secondary structure

..................... 115
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P01635 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 4F41E3D40C539DEC

FASTA11512,581
        10         20         30         40         50         60 
MSVLTQVLAL LLLWLTGARC DIQMTQSPAS LSASVGETVT ITCRASGNIH NYLAWYQQKQ 

        70         80         90        100        110 
GKSPQLLVYN AKTLADGVPS RFSGSGSGTQ YSLKINSLQP EDFGSYYCQH FWSTP 

« Hide

References

[1]"Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes."
Nishioka Y., Leder P.
J. Biol. Chem. 255:3691-3694(1980) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
V00778 Genomic DNA. Translation: CAA24155.1.
PIRKVMSK2. A01918.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1A2YX-ray1.50A21-115[»]
1A7NX-ray2.01L21-115[»]
1A7OX-ray2.00L21-115[»]
1A7PX-ray2.01L21-115[»]
1A7QX-ray2.00L21-115[»]
1A7RX-ray2.01L21-115[»]
1DVFX-ray1.90A21-115[»]
1KIPX-ray2.10A21-115[»]
1KIQX-ray1.85A21-115[»]
1QBLX-ray2.26L21-115[»]
1QBMX-ray2.37L21-115[»]
1VFAX-ray1.80A21-115[»]
1VFBX-ray1.80A21-115[»]
1WEJX-ray1.80L21-115[»]
ProteinModelPortalP01635.
SMRP01635. Positions 21-115.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-1512510.
STRING10090.ENSMUSP00000100170.

Protein family/group databases

IMGTSearch...

Proteomic databases

MaxQBP01635.
PaxDbP01635.
PRIDEP01635.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000103369; ENSMUSP00000100170; ENSMUSG00000095007.

Phylogenomic databases

eggNOGNOG72718.
HOGENOMHOG000059537.
HOVERGENHBG018013.
InParanoidP01635.
OMATCRASAN.

Gene expression databases

BgeeP01635.
GenevestigatorP01635.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamPF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00406. IGv. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP01635.

Entry information

Entry nameKV5A3_MOUSE
AccessionPrimary (citable) accession number: P01635
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: July 9, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references