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Protein

Ig kappa chain V-V region K2

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-V region K2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Add BLAST20
ChainiPRO_000001519121 – ›115Ig kappa chain V-V region K2Add BLAST›95

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 108PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP01635.
PRIDEiP01635.

Expressioni

Gene expression databases

BgeeiENSMUSG00000095007.

Interactioni

Protein-protein interaction databases

MINTiMINT-1512510.

Structurei

Secondary structure

1115
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi24 – 27Combined sources4
Beta strandi29 – 33Combined sources5
Beta strandi39 – 47Combined sources9
Beta strandi53 – 58Combined sources6
Beta strandi65 – 69Combined sources5
Turni70 – 72Combined sources3
Beta strandi82 – 87Combined sources6
Beta strandi90 – 97Combined sources8
Helixi100 – 102Combined sources3
Beta strandi104 – 110Combined sources7
Beta strandi112 – 115Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A2YX-ray1.50A21-115[»]
1A7NX-ray2.01L21-115[»]
1A7OX-ray2.00L21-115[»]
1A7PX-ray2.01L21-115[»]
1A7QX-ray2.00L21-115[»]
1A7RX-ray2.01L21-115[»]
1DVFX-ray1.90A21-115[»]
1KIPX-ray2.10A21-115[»]
1KIQX-ray1.85A21-115[»]
1QBLX-ray2.26L21-115[»]
1QBMX-ray2.37L21-115[»]
1VFAX-ray1.80A21-115[»]
1VFBX-ray1.80A21-115[»]
1WEJX-ray1.80L21-115[»]
ProteinModelPortaliP01635.
SMRiP01635.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01635.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 43Framework-1Add BLAST23
Regioni44 – 54Complementarity-determining-1Add BLAST11
Regioni55 – 69Framework-2Add BLAST15
Regioni70 – 76Complementarity-determining-27
Regioni77 – 108Framework-3Add BLAST32
Regioni109 – ›115Complementarity-determining-3›7

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

GeneTreeiENSGT00860000133996.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
OMAiRESVLVI.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01635-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVLTQVLAL LLLWLTGARC DIQMTQSPAS LSASVGETVT ITCRASGNIH
60 70 80 90 100
NYLAWYQQKQ GKSPQLLVYN AKTLADGVPS RFSGSGSGTQ YSLKINSLQP
110
EDFGSYYCQH FWSTP
Length:115
Mass (Da):12,581
Last modified:July 21, 1986 - v1
Checksum:i4F41E3D40C539DEC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1151

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00778 Genomic DNA. Translation: CAA24155.1.
PIRiA01918. KVMSK2.

Genome annotation databases

EnsembliENSMUST00000103369; ENSMUSP00000100170; ENSMUSG00000095007.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00778 Genomic DNA. Translation: CAA24155.1.
PIRiA01918. KVMSK2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A2YX-ray1.50A21-115[»]
1A7NX-ray2.01L21-115[»]
1A7OX-ray2.00L21-115[»]
1A7PX-ray2.01L21-115[»]
1A7QX-ray2.00L21-115[»]
1A7RX-ray2.01L21-115[»]
1DVFX-ray1.90A21-115[»]
1KIPX-ray2.10A21-115[»]
1KIQX-ray1.85A21-115[»]
1QBLX-ray2.26L21-115[»]
1QBMX-ray2.37L21-115[»]
1VFAX-ray1.80A21-115[»]
1VFBX-ray1.80A21-115[»]
1WEJX-ray1.80L21-115[»]
ProteinModelPortaliP01635.
SMRiP01635.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1512510.

Protein family/group databases

IMGTiSearch...

Proteomic databases

MaxQBiP01635.
PRIDEiP01635.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000103369; ENSMUSP00000100170; ENSMUSG00000095007.

Phylogenomic databases

GeneTreeiENSGT00860000133996.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
OMAiRESVLVI.

Miscellaneous databases

EvolutionaryTraceiP01635.

Gene expression databases

BgeeiENSMUSG00000095007.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKV5A3_MOUSE
AccessioniPrimary (citable) accession number: P01635
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 30, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

The gene was isolated and sequenced separately from two different sources, embryos and cultured plasmacytoma cells that secrete the similar kappa chain MOPC 149.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.