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Protein

Ig kappa chain V-V region K2

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

The gene was isolated and sequenced separately from two different sources, embryos and cultured plasmacytoma cells that secrete the similar kappa chain MOPC 149.

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-V region K2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Add BLAST20
ChainiPRO_000001519121 – ›115Ig kappa chain V-V region K2Add BLAST›95

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 108

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP01635.
PRIDEiP01635.

Expressioni

Gene expression databases

BgeeiENSMUSG00000095007.
ExpressionAtlasiP01635. baseline and differential.

Interactioni

Protein-protein interaction databases

MINTiMINT-1512510.

Structurei

Secondary structure

1115
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi24 – 27Combined sources4
Beta strandi29 – 33Combined sources5
Beta strandi39 – 47Combined sources9
Beta strandi53 – 58Combined sources6
Beta strandi65 – 69Combined sources5
Turni70 – 72Combined sources3
Beta strandi82 – 87Combined sources6
Beta strandi90 – 97Combined sources8
Helixi100 – 102Combined sources3
Beta strandi104 – 110Combined sources7
Beta strandi112 – 115Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A2YX-ray1.50A21-115[»]
1A7NX-ray2.01L21-115[»]
1A7OX-ray2.00L21-115[»]
1A7PX-ray2.01L21-115[»]
1A7QX-ray2.00L21-115[»]
1A7RX-ray2.01L21-115[»]
1DVFX-ray1.90A21-115[»]
1KIPX-ray2.10A21-115[»]
1KIQX-ray1.85A21-115[»]
1QBLX-ray2.26L21-115[»]
1QBMX-ray2.37L21-115[»]
1VFAX-ray1.80A21-115[»]
1VFBX-ray1.80A21-115[»]
1WEJX-ray1.80L21-115[»]
ProteinModelPortaliP01635.
SMRiP01635.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01635.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 43Framework-1Add BLAST23
Regioni44 – 54Complementarity-determining-1Add BLAST11
Regioni55 – 69Framework-2Add BLAST15
Regioni70 – 76Complementarity-determining-27
Regioni77 – 108Framework-3Add BLAST32
Regioni109 – ›115Complementarity-determining-3›7

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

GeneTreeiENSGT00900000141467.
HOGENOMiHOG000059537.
HOVERGENiHBG018013.
OMAiARTQTTK.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
PfamiView protein in Pfam
PF07686. V-set. 1 hit.
SMARTiView protein in SMART
SM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01635-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVLTQVLAL LLLWLTGARC DIQMTQSPAS LSASVGETVT ITCRASGNIH
60 70 80 90 100
NYLAWYQQKQ GKSPQLLVYN AKTLADGVPS RFSGSGSGTQ YSLKINSLQP
110
EDFGSYYCQH FWSTP
Length:115
Mass (Da):12,581
Last modified:July 21, 1986 - v1
Checksum:i4F41E3D40C539DEC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1151

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00778 Genomic DNA. Translation: CAA24155.1.
PIRiA01918. KVMSK2.

Genome annotation databases

EnsembliENSMUST00000103369; ENSMUSP00000100170; ENSMUSG00000095007.

Similar proteinsi

Entry informationi

Entry nameiKV5A3_MOUSE
AccessioniPrimary (citable) accession number: P01635
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: October 25, 2017
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references