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P01635

- KV5A3_MOUSE

UniProt

P01635 - KV5A3_MOUSE

Protein

Ig kappa chain V-V region K2

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. antigen binding Source: UniProtKB-KW

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ig kappa chain V-V region K2
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Add
    BLAST
    Chaini21 – ›115›95Ig kappa chain V-V region K2PRO_0000015191Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi43 ↔ 108PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    MaxQBiP01635.
    PaxDbiP01635.
    PRIDEiP01635.

    Expressioni

    Gene expression databases

    BgeeiP01635.
    GenevestigatoriP01635.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1512510.
    STRINGi10090.ENSMUSP00000100170.

    Structurei

    Secondary structure

    1
    115
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi24 – 274
    Beta strandi29 – 335
    Beta strandi39 – 479
    Beta strandi53 – 586
    Beta strandi65 – 695
    Turni70 – 723
    Beta strandi82 – 876
    Beta strandi90 – 978
    Helixi100 – 1023
    Beta strandi104 – 1107
    Beta strandi112 – 1154

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1A2YX-ray1.50A21-115[»]
    1A7NX-ray2.01L21-115[»]
    1A7OX-ray2.00L21-115[»]
    1A7PX-ray2.01L21-115[»]
    1A7QX-ray2.00L21-115[»]
    1A7RX-ray2.01L21-115[»]
    1DVFX-ray1.90A21-115[»]
    1KIPX-ray2.10A21-115[»]
    1KIQX-ray1.85A21-115[»]
    1QBLX-ray2.26L21-115[»]
    1QBMX-ray2.37L21-115[»]
    1VFAX-ray1.80A21-115[»]
    1VFBX-ray1.80A21-115[»]
    1WEJX-ray1.80L21-115[»]
    ProteinModelPortaliP01635.
    SMRiP01635. Positions 21-115.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP01635.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 4323Framework-1Add
    BLAST
    Regioni44 – 5411Complementarity-determining-1Add
    BLAST
    Regioni55 – 6915Framework-2Add
    BLAST
    Regioni70 – 767Complementarity-determining-2
    Regioni77 – 10832Framework-3Add
    BLAST
    Regioni109 – ›115›7Complementarity-determining-3

    Keywords - Domaini

    Immunoglobulin domain, Immunoglobulin V region, Signal

    Phylogenomic databases

    eggNOGiNOG72718.
    HOGENOMiHOG000059537.
    HOVERGENiHBG018013.
    InParanoidiP01635.
    OMAiTCRASAN.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view]
    PfamiPF07686. V-set. 1 hit.
    [Graphical view]
    SMARTiSM00406. IGv. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P01635-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVLTQVLAL LLLWLTGARC DIQMTQSPAS LSASVGETVT ITCRASGNIH    50
    NYLAWYQQKQ GKSPQLLVYN AKTLADGVPS RFSGSGSGTQ YSLKINSLQP 100
    EDFGSYYCQH FWSTP 115
    Length:115
    Mass (Da):12,581
    Last modified:July 21, 1986 - v1
    Checksum:i4F41E3D40C539DEC
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei115 – 1151

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    V00778 Genomic DNA. Translation: CAA24155.1.
    PIRiA01918. KVMSK2.

    Genome annotation databases

    EnsembliENSMUST00000103369; ENSMUSP00000100170; ENSMUSG00000095007.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    V00778 Genomic DNA. Translation: CAA24155.1 .
    PIRi A01918. KVMSK2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1A2Y X-ray 1.50 A 21-115 [» ]
    1A7N X-ray 2.01 L 21-115 [» ]
    1A7O X-ray 2.00 L 21-115 [» ]
    1A7P X-ray 2.01 L 21-115 [» ]
    1A7Q X-ray 2.00 L 21-115 [» ]
    1A7R X-ray 2.01 L 21-115 [» ]
    1DVF X-ray 1.90 A 21-115 [» ]
    1KIP X-ray 2.10 A 21-115 [» ]
    1KIQ X-ray 1.85 A 21-115 [» ]
    1QBL X-ray 2.26 L 21-115 [» ]
    1QBM X-ray 2.37 L 21-115 [» ]
    1VFA X-ray 1.80 A 21-115 [» ]
    1VFB X-ray 1.80 A 21-115 [» ]
    1WEJ X-ray 1.80 L 21-115 [» ]
    ProteinModelPortali P01635.
    SMRi P01635. Positions 21-115.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1512510.
    STRINGi 10090.ENSMUSP00000100170.

    Protein family/group databases

    IMGTi Search...

    Proteomic databases

    MaxQBi P01635.
    PaxDbi P01635.
    PRIDEi P01635.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000103369 ; ENSMUSP00000100170 ; ENSMUSG00000095007 .

    Phylogenomic databases

    eggNOGi NOG72718.
    HOGENOMi HOG000059537.
    HOVERGENi HBG018013.
    InParanoidi P01635.
    OMAi TCRASAN.

    Miscellaneous databases

    EvolutionaryTracei P01635.

    Gene expression databases

    Bgeei P01635.
    Genevestigatori P01635.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    [Graphical view ]
    Pfami PF07686. V-set. 1 hit.
    [Graphical view ]
    SMARTi SM00406. IGv. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes."
      Nishioka Y., Leder P.
      J. Biol. Chem. 255:3691-3694(1980) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiKV5A3_MOUSE
    AccessioniPrimary (citable) accession number: P01635
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: July 21, 1986
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    The gene was isolated and sequenced separately from two different sources, embryos and cultured plasmacytoma cells that secrete the similar kappa chain MOPC 149.

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3