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P01622 (KV304_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ig kappa chain V-III region Ti
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length109 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

The C region of this chain has the INV (3) marker.

This is a Bence-Jones protein.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›109›109Ig kappa chain V-III region Ti
PRO_0000059764

Amino acid modifications

Disulfide bond23 ↔ 89 By similarity

Experimental info

Non-terminal residue1091

Sequences

Sequence LengthMass (Da)Tools
P01622 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 8C35058CDC7749BC

FASTA10911,788
        10         20         30         40         50         60 
EIVLTQSPGT LSLSPGERAT LSCRASQSVS NSFLAWYQQK PGQAPRLLIY VASSRATGIP 

        70         80         90        100 
DRFSGSGSGT DFTLTISRLE PEDFAVYYCQ QYGSSPSTFG QGTKVELKR 

« Hide

References

[1]"Rule of antibody structure. The primary structure of a monoclonal immunoglobulin L-chain of kappa-type, subgroup 3 (Bence-Jones protein Ti). IV. The complete amino acid sequence and its significance for the mechanism of antibody production."
Suter L., Barnikol H.U., Watanabe S., Hilschmann N.
Hoppe-Seyler's Z. Physiol. Chem. 353:189-208(1972) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases

PIRK3HUTI. A01895.

3D structure databases

ProteinModelPortalP01622.
SMRP01622. Positions 1-109.
ModBaseSearch...
MobiDBSearch...

Polymorphism databases

DMDM125801.

Proteomic databases

PRIDEP01622.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG018013.
PhylomeDBP01622.

Enzyme and pathway databases

ReactomeREACT_160300. Binding and Uptake of Ligands by Scavenger Receptors.
REACT_6900. Immune System.

Gene expression databases

GenevestigatorP01622.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamPF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00406. IGv. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKV304_HUMAN
AccessionPrimary (citable) accession number: P01622
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.