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Protein

Enterotoxin type C-1

Gene

entC1

Organism
Staphylococcus aureus
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death.

GO - Molecular functioni

Keywordsi

Molecular functionEnterotoxin, Superantigen, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Enterotoxin type C-1
Alternative name(s):
SEC1
Gene namesi
Name:entC1
OrganismiStaphylococcus aureus
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Protein family/group databases

Allergomei2141 Sta a SEC

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 271 PublicationAdd BLAST27
ChainiPRO_000003560728 – 266Enterotoxin type C-11 PublicationAdd BLAST239

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi120 ↔ 1371 Publication

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP01553
SMRiP01553
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR008992 Enterotoxin
IPR006126 Staph/Strept_toxin_CS
IPR006173 Staph_tox_OB
IPR016091 SuperAg_toxin_C
IPR013307 Superantigen_bac
IPR006123 Toxin_b-grasp_Staph/Strep
IPR006177 Toxin_bac
PfamiView protein in Pfam
PF02876 Stap_Strp_tox_C, 1 hit
PF01123 Stap_Strp_toxin, 1 hit
PRINTSiPR00279 BACTRLTOXIN
PR01898 SAGSUPRFAMLY
SUPFAMiSSF50203 SSF50203, 1 hit
SSF54334 SSF54334, 1 hit
PROSITEiView protein in PROSITE
PS00277 STAPH_STREP_TOXIN_1, 1 hit
PS00278 STAPH_STREP_TOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01553-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKSRFISCV ILIFALILVL FTPNVLAESQ PDPTPDELHK ASKFTGLMEN
60 70 80 90 100
MKVLYDDHYV SATKVKSVDK FLAHDLIYNI SDKKLKNYDK VKTELLNEGL
110 120 130 140 150
AKKYKDEVVD VYGSNYYVNC YFSSKDNVGK VTGGKTCMYG GITKHEGNHF
160 170 180 190 200
DNGNLQNVLI RVYENKRNTI SFEVQTDKKS VTAQELDIKA RNFLINKKNL
210 220 230 240 250
YEFNSSPYET GYIKFIENNG NTFWYDMMPA PGDKFDQSKY LMMYNDNKTV
260
DSKSVKIEVH LTTKNG
Length:266
Mass (Da):30,546
Last modified:January 1, 1990 - v2
Checksum:i3A7AB59A8986853B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti177D → N AA sequence (PubMed:6189824).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05815 Genomic DNA Translation: CAA29260.1
PIRiS06356 ENSAC1
RefSeqiWP_001043549.1, NZ_OFYF01000066.1

Similar proteinsi

Entry informationi

Entry nameiENTC1_STAAU
AccessioniPrimary (citable) accession number: P01553
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 1, 1990
Last modified: May 23, 2018
This is version 92 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

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