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P01553

- ENTC1_STAAU

UniProt

P01553 - ENTC1_STAAU

Protein

Enterotoxin type C-1

Gene

entC1

Organism
Staphylococcus aureus
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 2 (01 Jan 1990)
      Previous versions | rss
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    Functioni

    Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death.

    GO - Biological processi

    1. pathogenesis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Enterotoxin, Superantigen, Toxin

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Enterotoxin type C-1
    Alternative name(s):
    SEC1
    Gene namesi
    Name:entC1
    OrganismiStaphylococcus aureus
    Taxonomic identifieri1280 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Protein family/group databases

    Allergomei2141. Sta a SEC.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 27271 PublicationAdd
    BLAST
    Chaini28 – 266239Enterotoxin type C-11 PublicationPRO_0000035607Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi120 ↔ 1371 Publication

    Keywords - PTMi

    Disulfide bond

    Structurei

    3D structure databases

    ProteinModelPortaliP01553.
    SMRiP01553. Positions 28-264.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di3.10.20.120. 1 hit.
    InterProiIPR008992. Enterotoxin.
    IPR006126. Staph/Strept_toxin_CS.
    IPR006173. Staph_tox_OB.
    IPR016091. SuperAg_toxin_C.
    IPR013307. Superantigen_bac.
    IPR006123. Toxin_b-grasp_Staph/Strep.
    IPR006177. Toxin_bac.
    [Graphical view]
    PfamiPF02876. Stap_Strp_tox_C. 1 hit.
    PF01123. Stap_Strp_toxin. 1 hit.
    [Graphical view]
    PRINTSiPR00279. BACTRLTOXIN.
    PR01898. SAGSUPRFAMLY.
    SUPFAMiSSF50203. SSF50203. 1 hit.
    SSF54334. SSF54334. 1 hit.
    PROSITEiPS00277. STAPH_STREP_TOXIN_1. 1 hit.
    PS00278. STAPH_STREP_TOXIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P01553-1 [UniParc]FASTAAdd to Basket

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    MNKSRFISCV ILIFALILVL FTPNVLAESQ PDPTPDELHK ASKFTGLMEN    50
    MKVLYDDHYV SATKVKSVDK FLAHDLIYNI SDKKLKNYDK VKTELLNEGL 100
    AKKYKDEVVD VYGSNYYVNC YFSSKDNVGK VTGGKTCMYG GITKHEGNHF 150
    DNGNLQNVLI RVYENKRNTI SFEVQTDKKS VTAQELDIKA RNFLINKKNL 200
    YEFNSSPYET GYIKFIENNG NTFWYDMMPA PGDKFDQSKY LMMYNDNKTV 250
    DSKSVKIEVH LTTKNG 266
    Length:266
    Mass (Da):30,546
    Last modified:January 1, 1990 - v2
    Checksum:i3A7AB59A8986853B
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti177 – 1771D → N AA sequence (PubMed:6189824)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X05815 Genomic DNA. Translation: CAA29260.1.
    PIRiS06356. ENSAC1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X05815 Genomic DNA. Translation: CAA29260.1 .
    PIRi S06356. ENSAC1.

    3D structure databases

    ProteinModelPortali P01553.
    SMRi P01553. Positions 28-264.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 2141. Sta a SEC.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    PROi P01553.

    Family and domain databases

    Gene3Di 3.10.20.120. 1 hit.
    InterProi IPR008992. Enterotoxin.
    IPR006126. Staph/Strept_toxin_CS.
    IPR006173. Staph_tox_OB.
    IPR016091. SuperAg_toxin_C.
    IPR013307. Superantigen_bac.
    IPR006123. Toxin_b-grasp_Staph/Strep.
    IPR006177. Toxin_bac.
    [Graphical view ]
    Pfami PF02876. Stap_Strp_tox_C. 1 hit.
    PF01123. Stap_Strp_toxin. 1 hit.
    [Graphical view ]
    PRINTSi PR00279. BACTRLTOXIN.
    PR01898. SAGSUPRFAMLY.
    SUPFAMi SSF50203. SSF50203. 1 hit.
    SSF54334. SSF54334. 1 hit.
    PROSITEi PS00277. STAPH_STREP_TOXIN_1. 1 hit.
    PS00278. STAPH_STREP_TOXIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the staphylococcal enterotoxin C1 gene and relatedness to other pyrogenic toxins."
      Bohach G.A., Schlievert P.M.
      Mol. Gen. Genet. 209:15-20(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "The complete amino acid sequence of staphylococcal enterotoxin C1."
      Schmidt J.J., Spero L.
      J. Biol. Chem. 258:6300-6306(1983) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 28-266.

    Entry informationi

    Entry nameiENTC1_STAAU
    AccessioniPrimary (citable) accession number: P01553
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: January 1, 1990
    Last modified: October 1, 2014
    This is version 79 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3