Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P01505 (BMN_BOMVA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Bombinin
OrganismBombina variegata (Yellow-bellied toad)
Taxonomic identifier8348 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraBombinatoridaeBombina

Protein attributes

Sequence length24 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Has antimicrobial and hemolytic activities.

Subcellular location

Secreted.

Tissue specificity

Expressed by the skin glands.

Sequence similarities

Belongs to the bombinin family.

Caution

Residue 20 is assigned as E by similarity to other bombin sequences instead of Z (Glutamic acid or Gutamine) given in the original sequence by the authors.

Ontologies

Keywords
   Biological processCytolysis
Hemolysis
   Cellular componentSecreted
   Molecular functionAmphibian defense peptide
Antibiotic
Antimicrobial
   PTMAmidation
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processdefense response to bacterium

Inferred from electronic annotation. Source: UniProtKB-KW

hemolysis in other organism

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Peptide1 – 2424Bombinin
PRO_0000043500

Amino acid modifications

Modified residue241Asparagine amide

Sequences

Sequence LengthMass (Da)Tools
P01505 [UniParc].

Last modified September 22, 2009. Version 2.
Checksum: ACC0FCE3A5D02E85

FASTA242,295
        10         20 
GIGALSAKGA LKGLAKGLAE HFAN 

« Hide

References

[1]"Isolation and structural resolution of a haemolytically active polypeptide from the immune secretion of a European toad."
Csordas A., Michl H.
Monatsh. Chem. 101:182-189(1970)
Cited for: PROTEIN SEQUENCE.
Tissue: Skin secretion.

Cross-references

Sequence databases

PIRBMTD. A01766.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameBMN_BOMVA
AccessionPrimary (citable) accession number: P01505
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: September 22, 2009
Last modified: February 19, 2014
This is version 49 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families