Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Bombinin

Gene
N/A
Organism
Bombina variegata (Yellow-bellied toad)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Has antimicrobial and hemolytic activities.

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Amphibian defense peptide, Antibiotic, Antimicrobial

Keywords - Biological processi

Cytolysis, Hemolysis

Names & Taxonomyi

Protein namesi
Recommended name:
Bombinin
OrganismiBombina variegata (Yellow-bellied toad)
Taxonomic identifieri8348 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraBombinatoridaeBombina

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Peptidei1 – 2424BombininPRO_0000043500Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei24 – 241Asparagine amide

Keywords - PTMi

Amidation

Expressioni

Tissue specificityi

Expressed by the skin glands.

Family & Domainsi

Sequence similaritiesi

Belongs to the bombinin family.Curated

Sequencei

Sequence statusi: Complete.

P01505-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
GIGALSAKGA LKGLAKGLAE HFAN
Length:24
Mass (Da):2,295
Last modified:September 22, 2009 - v2
Checksum:iACC0FCE3A5D02E85
GO

Sequence databases

PIRiA01766. BMTD.

Cross-referencesi

Sequence databases

PIRiA01766. BMTD.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Isolation and structural resolution of a haemolytically active polypeptide from the immune secretion of a European toad."
    Csordas A., Michl H.
    Monatsh. Chem. 101:182-189(1970)
    Cited for: PROTEIN SEQUENCE.
    Tissue: Skin secretion.

Entry informationi

Entry nameiBMN_BOMVA
AccessioniPrimary (citable) accession number: P01505
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: September 22, 2009
Last modified: January 7, 2015
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Caution

Residue 20 is assigned as E by similarity to other bombin sequences instead of Z (Glutamic acid or Gutamine) given in the original sequence by the authors.Curated

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.