P01158 (DSIP_RABIT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Delta sleep-inducing peptide Short name=DSIP
Organism	Oryctolagus cuniculus (Rabbit) [Reference proteome]
Taxonomic identifier	9986 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Lagomorpha › Leporidae › Oryctolagus

Protein attributes

Sequence length	9 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	When infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
Miscellaneous	This peptide was obtained from dialysates of occipital venous sinus blood from rabbits kept asleep by electric stimulation of the thalamus.

Ontologies

Keywords
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Peptide	1 – 9	9	Delta sleep-inducing peptide		PRO_0000044133

Sequences

	Sequence		Length	Mass (Da)
	P01158 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: DDD365BDDAA8787D	FASTA	9	849
	WAGGDASGE

References

[1]	"The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide." Monnier M., Dudler L., Gachter R., Maier P.F., Tobler H.J., Schoenenberger G.A. Experientia 33:548-552(1977) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE.
[2]	"The delta EEG (sleep)-inducing peptide (DSIP). XI. Amino-acid analysis, sequence, synthesis and activity of the nonapeptide." Schoenenberger G.A., Maier P.F., Tobler H.J., Wilson K., Monnier M. Pflugers Arch. 376:119-129(1978) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE, SYNTHESIS.
[3]	"Delta-sleep-inducing peptide (DSIP): an update." Graf M.V., Kastin A.J. Peptides 7:1165-1187(1986) [PubMed] [Europe PMC] [Abstract] Cited for: REVIEW.

Web resources

Protein Spotlight

When your day draws to an end - Issue 8 of March 2001

Cross-references

Sequence databases
PIR	QDRB. A01422.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

DSIP_RABIT

Accession

Primary (citable) accession number: P01158

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	April 3, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program