Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P01144

- SAUV_PHYSA

UniProt

P01144 - SAUV_PHYSA

Protein

Sauvagin

Gene
N/A
Organism
Phyllomedusa sauvagei (Sauvage's leaf frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Hypotensive and diuretic peptide.

    Keywords - Molecular functioni

    Hormone

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sauvagin
    Alternative name(s):
    Sauvagine
    Short name:
    SVG
    OrganismiPhyllomedusa sauvagei (Sauvage's leaf frog)
    Taxonomic identifieri8395 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaHyloideaHylidaePhyllomedusinaePhyllomedusa

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Peptidei1 – 4040SauvaginPRO_0000044693Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11Pyrrolidone carboxylic acid1 Publication
    Modified residuei40 – 401Isoleucine amide1 Publication

    Keywords - PTMi

    Amidation, Pyrrolidone carboxylic acid

    Structurei

    3D structure databases

    ProteinModelPortaliP01144.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR018446. Corticotropin-releasing_fac_CS.
    IPR000187. Corticotropin-releasing_factor.
    IPR003620. Urocortin_CRF.
    [Graphical view]
    PfamiPF00473. CRF. 1 hit.
    [Graphical view]
    PRINTSiPR01612. CRFFAMILY.
    SMARTiSM00039. CRF. 1 hit.
    [Graphical view]
    PROSITEiPS00511. CRF. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P01144-1 [UniParc]FASTAAdd to Basket

    « Hide

    QGPPISIDLS LELLRKMIEI EKQEKEKQQA ANNRLLLDTI              40
    Length:40
    Mass (Da):4,617
    Last modified:July 21, 1986 - v1
    Checksum:i1E3CD73D61128C4F
    GO

    Sequence databases

    PIRiA01406. SWFGS.

    Cross-referencesi

    Sequence databases

    PIRi A01406. SWFGS.

    3D structure databases

    ProteinModelPortali P01144.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR018446. Corticotropin-releasing_fac_CS.
    IPR000187. Corticotropin-releasing_factor.
    IPR003620. Urocortin_CRF.
    [Graphical view ]
    Pfami PF00473. CRF. 1 hit.
    [Graphical view ]
    PRINTSi PR01612. CRFFAMILY.
    SMARTi SM00039. CRF. 1 hit.
    [Graphical view ]
    PROSITEi PS00511. CRF. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structure of sauvagine, a vasoactive peptide from the skin of a frog."
      Montecucchi P.C., Henschen A., Erspamer V.
      Hoppe-Seyler's Z. Physiol. Chem. 360:1178-1178(1979)
      Cited for: PRELIMINARY PROTEIN SEQUENCE.
      Tissue: Skin secretion.
    2. "Amino acid composition and sequence analysis of sauvagine, a new active peptide from the skin of Phyllomedusa sauvagei."
      Montecucchi P.C., Anastasi A., de Castiglione R., Erspamer V.
      Int. J. Pept. Protein Res. 18:113-120(1981) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Tissue: Skin secretion.
    3. "Primary structure of sauvagine."
      Montecucchi P.C., Henschen A.
      Int. J. Pept. Protein Res. 19:325-325(1982) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Tissue: Skin secretion.
    4. "Studies on peptides. CLVII. Synthesis of frog-skin peptide, sauvagine."
      Nomizu M., Akaji K., Fukata J., Imura H., Inoue A., Nakata Y., Segawa T., Fujii N., Yajima H.
      Chem. Pharm. Bull. 36:122-133(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: SYNTHESIS.
    5. "Secondary structure prediction of sauvagine, a novel biologically active polypeptide from a frog."
      Montecucchi P.C., Gozzini L.
      Int. J. Pept. Protein Res. 20:139-143(1982) [PubMed] [Europe PMC] [Abstract]
      Cited for: SECONDARY STRUCTURE PREDICTION.

    Entry informationi

    Entry nameiSAUV_PHYSA
    AccessioniPrimary (citable) accession number: P01144
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: July 21, 1986
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3