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P01065

- IBB_VICSN

UniProt

P01065 - IBB_VICSN

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Protein

Bowman-Birk type proteinase inhibitor

Gene
N/A
Organism
Vicia sativa subsp. nigra (Common vetch) (Vicia angustifolia)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

This inhibitor has two domains, each with separate antiprotease activity. 1 mole of inhibitor inhibits either 1 mole of trypsin or 2 moles of chymotrypsin, stoichiometrically.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei16 – 172Reactive bond for trypsin
Sitei42 – 432Reactive bond for chymotrypsin

GO - Molecular functioni

  1. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI12.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Bowman-Birk type proteinase inhibitor
Alternative name(s):
VAI
OrganismiVicia sativa subsp. nigra (Common vetch) (Vicia angustifolia)
Taxonomic identifieri3909 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaeVicia

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7272Bowman-Birk type proteinase inhibitorPRO_0000105854Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi8 ↔ 61By similarity
Disulfide bondi9 ↔ 24By similarity
Disulfide bondi12 ↔ 57By similarity
Disulfide bondi14 ↔ 22By similarity
Disulfide bondi31 ↔ 38By similarity
Disulfide bondi35 ↔ 50By similarity
Disulfide bondi40 ↔ 48By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP01065.
SMRiP01065. Positions 1-67.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di2.10.69.10. 1 hit.
InterProiIPR000877. Prot_inh_BBI.
[Graphical view]
PfamiPF00228. Bowman-Birk_leg. 2 hits.
[Graphical view]
SMARTiSM00269. BowB. 1 hit.
[Graphical view]
SUPFAMiSSF57247. SSF57247. 1 hit.
PROSITEiPS00281. BOWMAN_BIRK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P01065-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GDDVKSACCD TCLCTRSQPP TCRCVDVGER CHSACNHCVC NYSNPPQCQC
60 70
FDTHKFCYKA CHSSEKEEVI KN
Length:72
Mass (Da):8,038
Last modified:July 21, 1986 - v1
Checksum:i21AADB275DE33D83
GO

Sequence databases

PIRiA01304. TIVTOA.

Cross-referencesi

Sequence databases

PIRi A01304. TIVTOA.

3D structure databases

ProteinModelPortali P01065.
SMRi P01065. Positions 1-67.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I12.003.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.10.69.10. 1 hit.
InterProi IPR000877. Prot_inh_BBI.
[Graphical view ]
Pfami PF00228. Bowman-Birk_leg. 2 hits.
[Graphical view ]
SMARTi SM00269. BowB. 1 hit.
[Graphical view ]
SUPFAMi SSF57247. SSF57247. 1 hit.
PROSITEi PS00281. BOWMAN_BIRK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete amino acid sequence of Vicia angustifolia proteinase inhibitor."
    Shimokawa Y., Kuromizu K., Araki T., Ohata J., Abe O.
    Nat. Cult. 10:69-73(1983)
    Cited for: PROTEIN SEQUENCE.
    Strain: cv. Segetalis.

Entry informationi

Entry nameiIBB_VICSN
AccessioniPrimary (citable) accession number: P01065
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3