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Protein

Bowman-Birk type proteinase inhibitor D-II

Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei32 – 332Reactive bond for trypsin
Sitei59 – 602Reactive bond for trypsin

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI12.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Bowman-Birk type proteinase inhibitor D-II
Alternative name(s):
IV
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
Proteomesi
  • UP000008827 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Propeptidei1 – 881 PublicationPRO_0000003284
Chaini9 – 8375Bowman-Birk type proteinase inhibitor D-IIPRO_0000003285Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi24 ↔ 78Combined sources1 Publication
Disulfide bondi25 ↔ 40Combined sources1 Publication
Disulfide bondi28 ↔ 74Combined sources1 Publication
Disulfide bondi30 ↔ 38Combined sources1 Publication
Disulfide bondi48 ↔ 55Combined sources1 Publication
Disulfide bondi52 ↔ 67Combined sources1 Publication
Disulfide bondi57 ↔ 65Combined sources1 Publication

Keywords - PTMi

Disulfide bond

Interactioni

Protein-protein interaction databases

STRINGi3847.GLYMA16G33400.1.

Structurei

Secondary structure

1
83
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi32 – 354Combined sources
Beta strandi53 – 575Combined sources
Beta strandi59 – 624Combined sources
Beta strandi64 – 674Combined sources
Beta strandi71 – 733Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PI2X-ray2.50A18-81[»]
ProteinModelPortaliP01064.
SMRiP01064. Positions 20-81.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01064.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di2.10.69.10. 1 hit.
InterProiIPR000877. Prot_inh_BBI.
[Graphical view]
PfamiPF00228. Bowman-Birk_leg. 2 hits.
[Graphical view]
SMARTiSM00269. BowB. 1 hit.
[Graphical view]
SUPFAMiSSF57247. SSF57247. 1 hit.
PROSITEiPS00281. BOWMAN_BIRK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01064-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCILSFLKSD QSSSYDDDEY SKPCCDLCMC TRSMPPQCSC EDIRLNSCHS
60 70 80
DCKSCMCTRS QPGQCRCLDT NDFCYKPCKS RDD
Length:83
Mass (Da):9,468
Last modified:July 1, 1989 - v2
Checksum:i55A5F9524373C20B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20733 mRNA. Translation: AAA33954.1.
PIRiS07941.
RefSeqiNP_001235006.1. NM_001248077.1.
UniGeneiGma.35602.

Genome annotation databases

GeneIDi548100.
KEGGigmx:548100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20733 mRNA. Translation: AAA33954.1.
PIRiS07941.
RefSeqiNP_001235006.1. NM_001248077.1.
UniGeneiGma.35602.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PI2X-ray2.50A18-81[»]
ProteinModelPortaliP01064.
SMRiP01064. Positions 20-81.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3847.GLYMA16G33400.1.

Protein family/group databases

MEROPSiI12.001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi548100.
KEGGigmx:548100.

Miscellaneous databases

EvolutionaryTraceiP01064.

Family and domain databases

Gene3Di2.10.69.10. 1 hit.
InterProiIPR000877. Prot_inh_BBI.
[Graphical view]
PfamiPF00228. Bowman-Birk_leg. 2 hits.
[Graphical view]
SMARTiSM00269. BowB. 1 hit.
[Graphical view]
SUPFAMiSSF57247. SSF57247. 1 hit.
PROSITEiPS00281. BOWMAN_BIRK. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Isolation and sequence of cDNA encoding the soybean protease inhibitors PI IV and C-II."
    Joudrier P.E., Foard D.E., Floener L.A., Larkins B.A.
    Plant Mol. Biol. 10:35-42(1987)
    [AGRICOLA] [Europe PMC]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "Studies on soybean trypsin inhibitors, XII. Linear sequences of two soybean double-headed trypsin inhibitors, D-II and E-I."
    Odani S., Ikenaka T.
    J. Biochem. 83:737-745(1978) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 9-83.
  3. "Reactive sites of an anticarcinogenic Bowman-Birk proteinase inhibitor are similar to other trypsin inhibitors."
    Chen P., Rose J., Love R., Wei C.H., Wang B.C.
    J. Biol. Chem. 267:1990-1994(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 18-81, DISULFIDE BONDS.

Entry informationi

Entry nameiIBBD2_SOYBN
AccessioniPrimary (citable) accession number: P01064
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 1, 1989
Last modified: January 20, 2016
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.