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Protein

Bowman-Birk type proteinase inhibitor DE-4

Gene
N/A
Organism
Macrotyloma axillare (Perennial horse gram) (Dolichos axillaris)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei23 – 242Reactive bond for trypsinBy similarity
Sitei50 – 512Reactive bond for chymotrypsinBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI12.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Bowman-Birk type proteinase inhibitor DE-4
OrganismiMacrotyloma axillare (Perennial horse gram) (Dolichos axillaris)
Taxonomic identifieri3876 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeMacrotyloma

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7676Bowman-Birk type proteinase inhibitor DE-4PRO_0000105842Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi15 ↔ 69By similarity
Disulfide bondi16 ↔ 31By similarity
Disulfide bondi19 ↔ 65By similarity
Disulfide bondi21 ↔ 291 Publication
Disulfide bondi39 ↔ 46By similarity
Disulfide bondi43 ↔ 58By similarity
Disulfide bondi48 ↔ 56By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1GM2NMR-A21-29[»]
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01059.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

CDDicd00023. BBI. 1 hit.
Gene3Di2.10.69.10. 1 hit.
InterProiIPR000877. Prot_inh_BBI.
[Graphical view]
PfamiPF00228. Bowman-Birk_leg. 1 hit.
[Graphical view]
SMARTiSM00269. BowB. 1 hit.
[Graphical view]
SUPFAMiSSF57247. SSF57247. 1 hit.
PROSITEiPS00281. BOWMAN_BIRK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P01059-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HEHSSDESSE SSKPCCDLCT CTKSIPPQCH CNDMRLNSCH SACKSCICAL
60 70
SEPAQCFCVD TTDFCYKSCH NNAEKD
Length:76
Mass (Da):8,369
Last modified:July 21, 1986 - v1
Checksum:i51703EB711D39806
GO

Sequence databases

PIRiA01298. TIAM4.

Cross-referencesi

Sequence databases

PIRiA01298. TIAM4.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1GM2NMR-A21-29[»]
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiI12.001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP01059.

Family and domain databases

CDDicd00023. BBI. 1 hit.
Gene3Di2.10.69.10. 1 hit.
InterProiIPR000877. Prot_inh_BBI.
[Graphical view]
PfamiPF00228. Bowman-Birk_leg. 1 hit.
[Graphical view]
SMARTiSM00269. BowB. 1 hit.
[Graphical view]
SUPFAMiSSF57247. SSF57247. 1 hit.
PROSITEiPS00281. BOWMAN_BIRK. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIBB4_MACAX
AccessioniPrimary (citable) accession number: P01059
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: September 7, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.