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Protein

Bowman-Birk type proteinase inhibitor

Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Inhibitor of trypsin and of chymotrypsin.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei55 – 56Reactive bond for trypsin2
Sitei82 – 83Reactive bond for chymotrypsin2

GO - Molecular functioni

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI12.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Bowman-Birk type proteinase inhibitor
Short name:
BBI
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
Proteomesi
  • UP000008827 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
PropeptideiPRO_000000328020 – 391 PublicationAdd BLAST20
ChainiPRO_000000328140 – 110Bowman-Birk type proteinase inhibitorAdd BLAST71

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi47 ↔ 1011 Publication
Disulfide bondi48 ↔ 631 Publication
Disulfide bondi51 ↔ 971 Publication
Disulfide bondi53 ↔ 611 Publication
Disulfide bondi71 ↔ 781 Publication
Disulfide bondi75 ↔ 901 Publication
Disulfide bondi80 ↔ 881 Publication

Keywords - PTMi

Disulfide bond

Expressioni

Developmental stagei

This protein is apparently expressed only in developing seeds.

Interactioni

Protein-protein interaction databases

IntActiP01055. 1 interactor.
MINTiMINT-129535.
STRINGi3847.GLYMA09G28730.1.

Structurei

Secondary structure

1110
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi49 – 58Combined sources10
Beta strandi61 – 63Combined sources3
Beta strandi66 – 69Combined sources4
Beta strandi78 – 80Combined sources3
Beta strandi82 – 85Combined sources4
Beta strandi87 – 90Combined sources4
Beta strandi94 – 96Combined sources3
Beta strandi104 – 106Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BBINMR-A40-110[»]
1D6RX-ray2.30I45-102[»]
1K9BX-ray2.80A45-102[»]
2BBINMR-A40-110[»]
5J4QX-ray2.30B40-110[»]
5J4SX-ray2.10B40-110[»]
ProteinModelPortaliP01055.
SMRiP01055.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01055.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

CDDicd00023. BBI. 1 hit.
InterProiView protein in InterPro
IPR000877. Prot_inh_BBI.
PfamiView protein in Pfam
PF00228. Bowman-Birk_leg. 2 hits.
SMARTiView protein in SMART
SM00269. BowB. 1 hit.
SUPFAMiSSF57247. SSF57247. 1 hit.
PROSITEiView protein in PROSITE
PS00281. BOWMAN_BIRK. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01055-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVLKVCLVL LFLVGGTTSA NLRLSKLGLL MKSDHQHSND DESSKPCCDQ
60 70 80 90 100
CACTKSNPPQ CRCSDMRLNS CHSACKSCIC ALSYPAQCFC VDITDFCYEP
110
CKPSEDDKEN
Length:110
Mass (Da):12,092
Last modified:October 1, 1996 - v2
Checksum:iDDE68317CA6AF54F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68704 mRNA. Translation: CAA48655.1.
K01968 mRNA. Translation: AAA19613.1.
PIRiJC2226. TISYO.
RefSeqiNP_001238547.1. NM_001251618.1.
UniGeneiGma.18051.
Gma.42.
Gma.55285.

Genome annotation databases

GeneIDi548083.
KEGGigmx:548083.

Similar proteinsi

Entry informationi

Entry nameiIBB1_SOYBN
AccessioniPrimary (citable) accession number: P01055
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: October 1, 1996
Last modified: September 27, 2017
This is version 111 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families