Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Subtilisin-chymotrypsin inhibitor-2A

Gene
N/A
Organism
Hordeum vulgare (Barley)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Inhibits both subtilisin and chymotrypsin.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei60 – 61Reactive bond2

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI13.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Subtilisin-chymotrypsin inhibitor-2A
Short name:
CI-2A
OrganismiHordeum vulgare (Barley)
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeHordeinaeHordeum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00002176492 – 84Subtilisin-chymotrypsin inhibitor-2AAdd BLAST83

Interactioni

Protein-protein interaction databases

IntActiP01053. 1 interactor.
MINTiMINT-242935.

Structurei

Secondary structure

184
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi26 – 28Combined sources3
Helixi33 – 43Combined sources11
Beta strandi48 – 53Combined sources6
Beta strandi57 – 59Combined sources3
Beta strandi66 – 71Combined sources6
Beta strandi75 – 77Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1CIQX-ray2.20A22-60[»]
B61-84[»]
1CIRNMR-A22-59[»]
B61-84[»]
1CISNMR-A22-84[»]
1COAX-ray2.20I22-84[»]
1CQ4X-ray1.80A21-59[»]
B61-84[»]
1LW6X-ray1.50I22-84[»]
1YPAX-ray2.00I22-84[»]
1YPBX-ray2.00I22-84[»]
1YPCX-ray1.70I22-84[»]
2CI2X-ray2.00I2-84[»]
2SNIX-ray2.10I2-84[»]
3CI2NMR-A19-84[»]
5FBZX-ray1.90B/D13-84[»]
5FFNX-ray1.80I13-84[»]
ProteinModelPortaliP01053.
SMRiP01053.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01053.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR000864. Prot_inh_pot1.
[Graphical view]
PfamiPF00280. potato_inhibit. 1 hit.
[Graphical view]
PRINTSiPR00292. POTATOINHBTR.
ProDomiPD002604. Prot_inh_pot1. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54654. SSF54654. 1 hit.
PROSITEiPS00285. POTATO_INHIBITOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01053-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSVEKKPEG VNTGAGDRHN LKTEWPELVG KSVEEAKKVI LQDKPEAQII
60 70 80
VLPVGTIVTM EYRIDRVRLF VDKLDNIAQV PRVG
Length:84
Mass (Da):9,381
Last modified:January 23, 2007 - v2
Checksum:i594849D2B837F0E4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti79Q → E AA sequence (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05404 mRNA. Translation: CAA28988.1.
PIRiA01292. EIBH2A.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05404 mRNA. Translation: CAA28988.1.
PIRiA01292. EIBH2A.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1CIQX-ray2.20A22-60[»]
B61-84[»]
1CIRNMR-A22-59[»]
B61-84[»]
1CISNMR-A22-84[»]
1COAX-ray2.20I22-84[»]
1CQ4X-ray1.80A21-59[»]
B61-84[»]
1LW6X-ray1.50I22-84[»]
1YPAX-ray2.00I22-84[»]
1YPBX-ray2.00I22-84[»]
1YPCX-ray1.70I22-84[»]
2CI2X-ray2.00I2-84[»]
2SNIX-ray2.10I2-84[»]
3CI2NMR-A19-84[»]
5FBZX-ray1.90B/D13-84[»]
5FFNX-ray1.80I13-84[»]
ProteinModelPortaliP01053.
SMRiP01053.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP01053. 1 interactor.
MINTiMINT-242935.

Protein family/group databases

MEROPSiI13.003.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP01053.

Family and domain databases

InterProiIPR000864. Prot_inh_pot1.
[Graphical view]
PfamiPF00280. potato_inhibit. 1 hit.
[Graphical view]
PRINTSiPR00292. POTATOINHBTR.
ProDomiPD002604. Prot_inh_pot1. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54654. SSF54654. 1 hit.
PROSITEiPS00285. POTATO_INHIBITOR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiICI2_HORVU
AccessioniPrimary (citable) accession number: P01053
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.