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Protein

Eglin C

Gene
N/A
Organism
Hirudo medicinalis (Medicinal leech)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Inhibits both elastase and cathepsin G.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei45 – 46Reactive bond2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI13.001

Names & Taxonomyi

Protein namesi
Recommended name:
Eglin C
OrganismiHirudo medicinalis (Medicinal leech)
Taxonomic identifieri6421 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaClitellataHirudineaArhynchobdellidaHirudiniformesHirudinidaeHirudo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002176451 – 70Eglin CAdd BLAST70

Interactioni

Protein-protein interaction databases

DIPiDIP-6069N
MINTiP01051

Structurei

Secondary structure

170
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi11 – 13Combined sources3
Helixi18 – 28Combined sources11
Beta strandi32 – 38Combined sources7
Beta strandi42 – 44Combined sources3
Beta strandi48 – 57Combined sources10
Turni58 – 61Combined sources4
Beta strandi68 – 70Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ACBX-ray2.00I1-70[»]
1CSEX-ray1.20I1-70[»]
1EGLNMR-A1-70[»]
1EGPX-ray2.00A1-45[»]
B46-70[»]
1MEEX-ray2.00I7-70[»]
1SBNX-ray2.10I1-70[»]
1SIBX-ray2.40I1-70[»]
1TECX-ray2.20I1-70[»]
2SECX-ray1.80I1-70[»]
2TECX-ray1.98I1-70[»]
3TECX-ray2.00I1-70[»]
4B1TX-ray1.78B/D1-70[»]
4B2AX-ray1.89B/D5-70[»]
4B2BX-ray1.36B/D1-70[»]
4B2CX-ray1.43B/D1-70[»]
4H4FX-ray1.90B8-70[»]
ProteinModelPortaliP01051
SMRiP01051
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01051

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR000864 Prot_inh_pot1
IPR036354 Prot_inh_pot1_sf
PANTHERiPTHR33091 PTHR33091, 1 hit
PfamiView protein in Pfam
PF00280 potato_inhibit, 1 hit
PRINTSiPR00292 POTATOINHBTR
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002604 Prot_inh_pot1, 1 hit
SUPFAMiSSF54654 SSF54654, 1 hit
PROSITEiView protein in PROSITE
PS00285 POTATO_INHIBITOR, 1 hit

Sequencei

Sequence statusi: Complete.

P01051-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
TEFGSELKSF PEVVGKTVDQ AREYFTLHYP QYDVYFLPEG SPVTLDLRYN
60 70
RVRVFYNPGT NVVNHVPHVG
Length:70
Mass (Da):8,091
Last modified:July 21, 1986 - v1
Checksum:i7E5C5BBD39DC3C11
GO

Sequence databases

PIRiA94592 EILXCH

Entry informationi

Entry nameiICIC_HIRME
AccessioniPrimary (citable) accession number: P01051
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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