P00720 (LYS_BPT4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Lysozyme
EC=3.2.1.17

Alternative name(s):
Endolysin
Lysis protein
Muramidase

Gene names

Name:

E

Organism

Enterobacteria phage T4 (Bacteriophage T4) [Reference proteome]

Taxonomic identifier

10665 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Caudovirales › Myoviridae › Tevenvirinae › T4likevirus › Enterobacteria phage T4 sensu lato

Virus host

Escherichia coli [TaxID: 562]

Protein attributes

Sequence length	164 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
Catalytic activity	Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
Sequence similarities	Belongs to the glycosyl hydrolase 24 family.

Ontologies

Keywords
Molecular function	Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro cytolysis Inferred from electronic annotation. Source: UniProtKB-KW defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan catabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	lysozyme activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 164

164

Lysozyme

PRO_0000218107

Sites

Active site

11

1

Proton donor

Active site

20

1

Nucleophile

Experimental info

Sequence conflict

12

1

G → R Ref.3

Sequence conflict

12

1

G → R Ref.4

Sequence conflict

137

1

R → I Ref.3

Sequence conflict

137

1

R → I Ref.4

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

164

Helix Strand Turn

Details...

Helix

3 – 11

9

Beta strand

14 – 19

6

Beta strand

21 – 23

3

Beta strand

25 – 28

4

Beta strand

31 – 33

3

Beta strand

35 – 37

3

Helix

39 – 50

12

Beta strand

55 – 57

3

Helix

62 – 64

3

Helix

68 – 79

12

Turn

82 – 84

3

Helix

85 – 90

6

Helix

93 – 106

14

Helix

108 – 112

5

Helix

115 – 122

8

Turn

123 – 125

3

Helix

126 – 133

8

Helix

137 – 141

5

Helix

143 – 155

13

Beta strand

156 – 158

3

Turn

159 – 161

3

Helix

162 – 164

3

Sequences

	Sequence		Length	Mass (Da)
	P00720 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 6042E2F77B6308A0	FASTA	164	18,635
	10 20 30 40 50 60 MNIFEMLRID EGLRLKIYKD TEGYYTIGIG HLLTKSPSLN AAKSELDKAI GRNCNGVITK 70 80 90 100 110 120 DEAEKLFNQD VDAAVRGILR NAKLKPVYDS LDAVRRCALI NMVFQMGETG VAGFTNSLRM 130 140 150 160 LQQKRWDEAA VNLAKSRWYN QTPNRAKRVI TTFRTGTWDA YKNL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The amino acid sequence of T4 phage lysozyme. IV. Dilute acid hydrolysis and the order of tryptic peptides." Inouye M., Imada M., Tsugita A. J. Biol. Chem. 245:3479-3484(1970) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE.
[2]	"Nucleotide sequence of the lysozyme gene of bacteriophage T4. Analysis of mutations involving repeated sequences." Owen J.E., Schultz D.W., Taylor A., Smith G.R. J. Mol. Biol. 165:229-248(1983) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Nucleotide sequence and analysis of the 58.3 to 65.5-kb early region of bacteriophage T4." Valerie K., Stevens J., Lynch M., Henderson E.E., de Riel J.K. Nucleic Acids Res. 14:8637-8654(1986) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[4]	"Bacteriophage T4 genome." Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W. Microbiol. Mol. Biol. Rev. 67:86-156(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The three dimensional structure of the lysozyme from bacteriophage T4." Matthews B.W., Remington S.J. Proc. Natl. Acad. Sci. U.S.A. 71:4178-4182(1974) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS).
[6]	"Structure of bacteriophage T4 lysozyme refined at 1.7-A resolution." Weaver L.H., Matthews B.W. J. Mol. Biol. 193:189-200(1987) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS).
[7]	"Atomic coordinates for T4 phage lysozyme." Remington S.J., ten Eyck L.F., Matthews B.W. Biochem. Biophys. Res. Commun. 75:265-270(1977) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS).
[8]	"Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3." Matsumura M., Becktel W.J., Matthews B.W. Nature 334:406-410(1988) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF MUTANT ILE-3.
[9]	"A mutant T4 lysozyme displays five different crystal conformations." Faber H.R., Matthews B.W. Nature 348:263-266(1990) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF MUTANT.
[10]	"A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene." Eriksson A.E., Baase W.A., Wozniak J.A., Matthews B.W. Nature 355:371-373(1992) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF MUTANT.
[11]	"Assignment of the backbone 1H and 15N NMR resonances of bacteriophage T4 lysozyme." McIntosh L.P., Wand A.J., Lowry D.F., Redfield A.G., Dahlquist F.W. Biochemistry 29:6341-6362(1990) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY NMR.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

X04567 Genomic DNA. Translation: CAA28212.1.
AF158101 Genomic DNA. Translation: AAD42568.1.

PIR

LZBPT4. A92896.

RefSeq

NP_049736.1. NC_000866.4.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
102L	X-ray	1.74	A	1-164	[»]
103L	X-ray	1.90	A	1-164	[»]
104L	X-ray	2.80	A/B	1-164	[»]
107L	X-ray	1.80	A	1-164	[»]
108L	X-ray	1.80	A	1-164	[»]
109L	X-ray	1.85	A	1-164	[»]
110L	X-ray	1.70	A	1-164	[»]
111L	X-ray	1.80	A	1-164	[»]
112L	X-ray	1.80	A	1-164	[»]
113L	X-ray	1.80	A	1-164	[»]
114L	X-ray	1.80	A	1-164	[»]
115L	X-ray	1.80	A	1-164	[»]
118L	X-ray	1.80	A	1-164	[»]
119L	X-ray	1.65	A	1-164	[»]
120L	X-ray	1.80	A	1-164	[»]
122L	X-ray	1.80	A	1-164	[»]
123L	X-ray	1.80	A	1-164	[»]
125L	X-ray	1.85	A	1-164	[»]
126L	X-ray	1.80	A	1-164	[»]
127L	X-ray	1.85	A	1-164	[»]
128L	X-ray	1.70	A	1-164	[»]
129L	X-ray	1.70	A	1-164	[»]
130L	X-ray	1.70	A	1-164	[»]
131L	X-ray	1.70	A	1-164	[»]
137L	X-ray	1.85	A/B	1-164	[»]
138L	X-ray	1.70	A	1-164	[»]
139L	X-ray	1.70	A	1-164	[»]
140L	X-ray	2.10	A	1-164	[»]
141L	X-ray	2.00	A	1-164	[»]
142L	X-ray	2.00	A	1-164	[»]
143L	X-ray	2.00	A	1-164	[»]
144L	X-ray	2.10	A	1-164	[»]
145L	X-ray	2.00	A	1-164	[»]
146L	X-ray	1.85	A	1-164	[»]
147L	X-ray	2.00	A	1-164	[»]
148L	X-ray	1.90	E	1-164	[»]
149L	X-ray	2.60	A	1-164	[»]
150L	X-ray	2.20	A/B/C/D	1-164	[»]
151L	X-ray	2.20	A	1-164	[»]
152L	X-ray	2.00	A	1-163	[»]
155L	X-ray	1.85	A	1-164	[»]
156L	X-ray	1.80	A	1-164	[»]
157L	X-ray	1.85	A	1-164	[»]
158L	X-ray	1.80	A	1-164	[»]
159L	X-ray	1.80	A	1-164	[»]
160L	X-ray	1.80	A	1-164	[»]
161L	X-ray	1.70	A	1-164	[»]
162L	X-ray	1.80	A	1-164	[»]
163L	X-ray	1.80	A	1-164	[»]
164L	X-ray	1.80	A	1-164	[»]
165L	X-ray	1.75	A	1-164	[»]
166L	X-ray	1.75	A	1-164	[»]
167L	X-ray	2.20	A/B	1-163	[»]
168L	X-ray	2.90	A/B/C/D/E	1-164	[»]
169L	X-ray	3.00	A/B/C/D/E	1-164	[»]
170L	X-ray	2.60	A	1-164	[»]
171L	X-ray	2.50	A	1-164	[»]
172L	X-ray	1.90	A	1-164	[»]
173L	X-ray	1.70	A	1-164	[»]
174L	X-ray	2.30	A/B	1-164	[»]
175L	X-ray	2.10	A/B	1-164	[»]
176L	X-ray	2.20	A/B	1-164	[»]
177L	X-ray	2.50	A	1-164	[»]
178L	X-ray	2.71	A	1-164	[»]
180L	X-ray	1.75	A/B	1-164	[»]
181L	X-ray	1.80	A	1-164	[»]
182L	X-ray	1.80	A	1-164	[»]
183L	X-ray	1.80	A	1-164	[»]
184L	X-ray	1.80	A	1-164	[»]
185L	X-ray	1.80	A	1-164	[»]
186L	X-ray	1.80	A	1-164	[»]
187L	X-ray	1.80	A	1-164	[»]
188L	X-ray	1.80	A	1-164	[»]
189L	X-ray	2.50	A	1-164	[»]
190L	X-ray	2.00	A	1-164	[»]
191L	X-ray	1.95	A	1-164	[»]
192L	X-ray	1.90	A	1-164	[»]
195L	X-ray	1.90	A	1-164	[»]
196L	X-ray	2.30	A	1-164	[»]
197L	X-ray	2.10	A	1-164	[»]
198L	X-ray	2.00	A	1-164	[»]
199L	X-ray	1.85	A	1-164	[»]
1B6I	X-ray	1.90	A	1-164	[»]
1C60	X-ray	2.00	A	1-164	[»]
1C61	X-ray	2.00	A	1-164	[»]
1C62	X-ray	2.30	A	1-164	[»]
1C63	X-ray	2.00	A	1-164	[»]
1C64	X-ray	2.00	A	1-164	[»]
1C65	X-ray	2.00	A	1-164	[»]
1C66	X-ray	2.10	A	1-164	[»]
1C67	X-ray	2.20	A	1-164	[»]
1C68	X-ray	2.50	A	1-164	[»]
1C69	X-ray	1.80	A	1-164	[»]
1C6A	X-ray	2.10	A	1-164	[»]
1C6B	X-ray	2.20	A	1-164	[»]
1C6C	X-ray	2.00	A	1-164	[»]
1C6D	X-ray	2.00	A	1-164	[»]
1C6E	X-ray	1.90	A	1-164	[»]
1C6F	X-ray	2.00	A	1-164	[»]
1C6G	X-ray	1.90	A	1-164	[»]
1C6H	X-ray	1.90	A	1-164	[»]
1C6I	X-ray	1.90	A	1-164	[»]
1C6J	X-ray	1.90	A	1-164	[»]
1C6K	X-ray	1.90	A	1-164	[»]
1C6L	X-ray	1.90	A	1-164	[»]
1C6M	X-ray	2.10	A	1-164	[»]
1C6N	X-ray	2.20	A	1-164	[»]
1C6P	X-ray	1.90	A	1-164	[»]
1C6Q	X-ray	1.90	A	1-164	[»]
1C6T	X-ray	2.00	A	1-164	[»]
1CTW	X-ray	2.10	A	1-164	[»]
1CU0	X-ray	2.20	A	1-164	[»]
1CU2	X-ray	1.85	A	1-164	[»]
1CU3	X-ray	2.12	A	1-164	[»]
1CU5	X-ray	2.05	A	1-164	[»]
1CU6	X-ray	2.10	A	1-164	[»]
1CUP	X-ray	1.89	A	1-164	[»]
1CUQ	X-ray	2.05	A	1-164	[»]
1CV0	X-ray	2.12	A	1-164	[»]
1CV1	X-ray	2.10	A	1-164	[»]
1CV3	X-ray	1.80	A	1-164	[»]
1CV4	X-ray	1.90	A	1-164	[»]
1CV5	X-ray	1.87	A	1-164	[»]
1CV6	X-ray	1.90	A	1-164	[»]
1CVK	X-ray	1.80	A	1-164	[»]
1CX6	X-ray	2.01	A	1-164	[»]
1CX7	X-ray	1.94	A	1-164	[»]
1D2W	X-ray	1.89	A	1-164	[»]
1D2Y	X-ray	2.06	A	1-164	[»]
1D3F	X-ray	2.05	A	1-164	[»]
1D3J	X-ray	1.97	A	1-164	[»]
1D3M	X-ray	2.12	A	1-164	[»]
1D3N	X-ray	2.00	A	1-164	[»]
1D9W	X-ray	1.70	A	1-164	[»]
1DYA	X-ray	1.90	A	1-164	[»]
1DYB	X-ray	1.75	A	1-164	[»]
1DYC	X-ray	2.10	A	1-164	[»]
1DYD	X-ray	2.10	A	1-164	[»]
1DYE	X-ray	1.80	A	1-164	[»]
1DYF	X-ray	1.90	A	1-164	[»]
1DYG	X-ray	2.10	A	1-164	[»]
1EPY	X-ray	1.85	A	1-164	[»]
1G06	X-ray	1.85	A	1-164	[»]
1G07	X-ray	1.70	A	1-164	[»]
1G0G	X-ray	1.90	A	1-164	[»]
1G0J	X-ray	1.80	A	1-164	[»]
1G0K	X-ray	1.85	A	1-164	[»]
1G0L	X-ray	1.80	A	1-164	[»]
1G0M	X-ray	1.70	A	1-164	[»]
1G0P	X-ray	1.80	A	1-164	[»]
1G0Q	X-ray	1.80	A	1-164	[»]
1G1V	X-ray	1.90	A	1-164	[»]
1G1W	X-ray	1.80	A	1-164	[»]
1I6S	X-ray	1.90	A	1-164	[»]
1JQU	X-ray	2.60	A/B/C/D	1-164	[»]
1JTM	X-ray	1.90	A	1-164	[»]
1JTN	X-ray	2.30	A/B	1-164	[»]
1KNI	X-ray	1.70	A	1-164	[»]
1KS3	X-ray	2.16	A	1-162	[»]
1KW5	X-ray	1.75	A	1-162	[»]
1KW7	X-ray	1.89	A	1-162	[»]
1KY0	X-ray	1.97	A	1-162	[»]
1KY1	X-ray	2.05	A	1-162	[»]
1L00	X-ray	1.90	A	1-164	[»]
1L01	X-ray	1.70	A	1-164	[»]
1L02	X-ray	1.70	A	1-164	[»]
1L03	X-ray	1.70	A	1-164	[»]
1L04	X-ray	1.70	A	1-164	[»]
1L05	X-ray	1.70	A	1-164	[»]
1L06	X-ray	1.70	A	1-164	[»]
1L07	X-ray	1.70	A	1-164	[»]
1L08	X-ray	1.70	A	1-164	[»]
1L09	X-ray	1.70	A	1-164	[»]
1L0J	X-ray	1.98	A	1-162	[»]
1L0K	X-ray	2.02	A	1-162	[»]
1L10	X-ray	1.70	A	1-164	[»]
1L11	X-ray	1.70	A	1-164	[»]
1L12	X-ray	1.70	A	1-164	[»]
1L13	X-ray	1.70	A	1-164	[»]
1L14	X-ray	1.70	A	1-164	[»]
1L15	X-ray	1.70	A	1-164	[»]
1L16	X-ray	1.70	A	1-164	[»]
1L17	X-ray	1.70	A	1-164	[»]
1L18	X-ray	1.70	A	1-164	[»]
1L19	X-ray	1.70	A	1-164	[»]
1L20	X-ray	1.85	A	1-164	[»]
1L21	X-ray	1.85	A	1-164	[»]
1L22	X-ray	1.70	A	1-164	[»]
1L23	X-ray	1.70	A	1-164	[»]
1L24	X-ray	1.70	A	1-164	[»]
1L25	X-ray	1.80	A	1-164	[»]
1L26	X-ray	1.70	A	1-164	[»]
1L27	X-ray	1.80	A	1-164	[»]
1L28	X-ray	1.90	A	1-164	[»]
1L29	X-ray	1.70	A	1-164	[»]
1L30	X-ray	1.70	A	1-164	[»]
1L31	X-ray	1.80	A	1-164	[»]
1L32	X-ray	1.70	A	1-164	[»]
1L33	X-ray	1.70	A	1-164	[»]
1L34	X-ray	1.90	A	1-164	[»]
1L35	X-ray	1.80	A	1-163	[»]
1L36	X-ray	1.70	A	1-164	[»]
1L37	X-ray	1.85	A	1-164	[»]
1L38	X-ray	1.80	A	1-164	[»]
1L39	X-ray	1.85	A	1-164	[»]
1L40	X-ray	1.85	A	1-164	[»]
1L41	X-ray	1.75	A	1-164	[»]
1L42	X-ray	1.80	A	1-164	[»]
1L43	X-ray	1.80	A	1-164	[»]
1L44	X-ray	1.70	A	1-164	[»]
1L45	X-ray	1.70	A	1-164	[»]
1L46	X-ray	1.70	A	1-164	[»]
1L47	X-ray	1.70	A	1-164	[»]
1L48	X-ray	1.70	A	1-164	[»]
1L49	X-ray	1.80	A	1-164	[»]
1L50	X-ray	1.85	A	1-164	[»]
1L51	X-ray	1.90	A	1-164	[»]
1L52	X-ray	1.70	A	1-164	[»]
1L53	X-ray	1.85	A	1-164	[»]
1L54	X-ray	1.90	A	1-164	[»]
1L55	X-ray	1.90	A	1-164	[»]
1L56	X-ray	1.80	A	1-164	[»]
1L57	X-ray	1.90	A	1-164	[»]
1L58	X-ray	1.65	A	1-164	[»]
1L59	X-ray	1.75	A	1-164	[»]
1L60	X-ray	1.70	A	1-164	[»]
1L61	X-ray	1.80	A	1-164	[»]
1L62	X-ray	1.70	A	1-164	[»]
1L63	X-ray	1.75	A	1-164	[»]
1L64	X-ray	1.90	A	1-164	[»]
1L65	X-ray	1.70	A	1-164	[»]
1L66	X-ray	1.70	A	1-164	[»]
1L67	X-ray	1.90	A	1-164	[»]
1L68	X-ray	1.70	A	1-164	[»]
1L69	X-ray	1.90	A	1-164	[»]
1L70	X-ray	1.90	A	1-164	[»]
1L71	X-ray	1.85	A	1-164	[»]
1L72	X-ray	1.85	A	1-164	[»]
1L73	X-ray	1.85	A	1-164	[»]
1L74	X-ray	1.70	A	1-164	[»]
1L75	X-ray	1.90	A	1-164	[»]
1L76	X-ray	1.90	A	1-164	[»]
1L77	X-ray	2.05	A	1-164	[»]
1L79	X-ray	1.90	A	1-164	[»]
1L80	X-ray	1.80	A	1-164	[»]
1L81	X-ray	2.00	A	1-164	[»]
1L82	X-ray	2.10	A	1-164	[»]
1L83	X-ray	1.70	A	1-164	[»]
1L84	X-ray	1.90	A	1-164	[»]
1L85	X-ray	2.00	A	1-164	[»]
1L86	X-ray	1.80	A	1-164	[»]
1L87	X-ray	1.80	A	1-164	[»]
1L88	X-ray	1.85	A	1-164	[»]
1L89	X-ray	1.90	A	1-164	[»]
1L90	X-ray	1.75	A	1-164	[»]
1L91	X-ray	1.80	A	1-164	[»]
1L92	X-ray	1.70	A	1-164	[»]
1L93	X-ray	1.80	A	1-164	[»]
1L94	X-ray	1.80	A	1-164	[»]
1L95	X-ray	2.00	A	1-164	[»]
1L96	X-ray	2.00	A	1-164	[»]
1L97	X-ray	2.00	A/B	1-164	[»]
1L98	X-ray	1.80	A	1-164	[»]
1L99	X-ray	1.95	A	1-164	[»]
1LGU	X-ray	1.90	A	1-164	[»]
1LGW	X-ray	1.85	A	1-164	[»]
1LGX	X-ray	1.90	A	1-164	[»]
1LI2	X-ray	2.00	A	1-164	[»]
1LI3	X-ray	1.85	A	1-164	[»]
1LI6	X-ray	2.00	A	1-164	[»]
1LLH	X-ray	1.80	A	1-164	[»]
1LPY	X-ray	1.65	A	1-164	[»]
1LW9	X-ray	1.45	A	1-164	[»]
1LWG	X-ray	1.70	A	1-164	[»]
1LWK	X-ray	2.10	A	1-164	[»]
1LYD	X-ray	2.00	A	1-164	[»]
1LYE	X-ray	1.80	A	1-164	[»]
1LYF	X-ray	1.80	A	1-164	[»]
1LYG	X-ray	1.80	A	1-164	[»]
1LYH	X-ray	1.70	A	1-164	[»]
1LYI	X-ray	2.00	A	1-164	[»]
1LYJ	X-ray	1.80	A	1-164	[»]
1NHB	X-ray	1.80	A	1-164	[»]
1OV5	X-ray	2.10	A	1-164	[»]
1OV7	X-ray	2.00	A	1-164	[»]
1OVH	X-ray	1.95	A	1-164	[»]
1OVJ	X-ray	2.00	A	1-164	[»]
1OVK	X-ray	2.10	A	1-164	[»]
1OWY	X-ray	1.90	A	1-164	[»]
1OWZ	X-ray	1.90	A	1-164	[»]
1OYU	X-ray	2.50	A/B	1-164	[»]
1P2L	X-ray	1.58	A	1-164	[»]
1P2R	X-ray	1.58	A	1-164	[»]
1P36	X-ray	1.45	A	1-164	[»]
1P37	X-ray	1.57	A	1-164	[»]
1P3N	X-ray	1.55	A	1-164	[»]
1P46	X-ray	1.67	A	1-164	[»]
1P56	X-ray	1.80	A	1-162	[»]
1P5C	X-ray	2.50	A/B/C/D	1-163	[»]
1P64	X-ray	1.62	A	1-164	[»]
1P6Y	X-ray	1.54	A	1-164	[»]
1P7S	X-ray	1.50	A	1-164	[»]
1PQD	X-ray	1.65	A	1-164	[»]
1PQI	X-ray	1.57	A	1-164	[»]
1PQJ	X-ray	1.90	A	1-164	[»]
1PQK	X-ray	2.00	A/B/C	1-164	[»]
1PQM	X-ray	1.52	A	1-164	[»]
1PQO	X-ray	1.65	A	1-164	[»]
1QS5	X-ray	2.50	A	1-162	[»]
1QS9	X-ray	1.85	A	1-162	[»]
1QSB	X-ray	1.80	A	1-162	[»]
1QSQ	X-ray	1.90	A	1-164	[»]
1QT3	X-ray	1.85	A	1-164	[»]
1QT4	X-ray	2.10	A	1-164	[»]
1QT5	X-ray	1.80	A	1-164	[»]
1QT6	X-ray	1.90	A	1-164	[»]
1QT7	X-ray	1.80	A	1-164	[»]
1QT8	X-ray	1.90	A	1-164	[»]
1QTB	X-ray	1.90	A	1-162	[»]
1QTC	X-ray	2.50	A	1-162	[»]
1QTD	X-ray	2.50	A	1-162	[»]
1QTH	X-ray	1.90	A/B	1-164	[»]
1QTV	X-ray	2.30	A	1-164	[»]
1QTZ	X-ray	2.00	A	1-164	[»]
1QUD	X-ray	1.75	A	1-162	[»]
1QUG	X-ray	1.90	A	1-162	[»]
1QUH	X-ray	1.85	A	1-162	[»]
1QUO	X-ray	1.90	A	1-162	[»]
1SSW	X-ray	2.13	A	1-164	[»]
1SSY	X-ray	2.40	A/B	1-164	[»]
1SWY	X-ray	1.06	A	1-164	[»]
1SWZ	X-ray	1.06	A	1-164	[»]
1SX2	X-ray	1.06	A	1-164	[»]
1SX7	X-ray	1.06	A	1-164	[»]
1T6H	X-ray	2.01	A	1-164	[»]
1T8A	X-ray	2.00	A	1-164	[»]
1T8F	X-ray	2.15	A	1-164	[»]
1T8G	X-ray	1.80	A	1-164	[»]
1T97	X-ray	2.70	A/B	1-164	[»]
1TLA	X-ray	2.00	A	1-164	[»]
1XEP	X-ray	1.55	A	1-164	[»]
1ZUR	X-ray	1.60	A	1-164	[»]
1ZWN	X-ray	1.80	A	1-164	[»]
1ZYT	X-ray	1.70	A	1-164	[»]
200L	X-ray	1.95	A	1-164	[»]
201L	X-ray	2.00	A/B	1-164	[»]
205L	X-ray	2.10	A	1-164	[»]
206L	X-ray	1.75	A	1-164	[»]
209L	X-ray	2.70	A	1-164	[»]
210L	X-ray	1.89	A	1-164	[»]
211L	X-ray	1.70	A	1-164	[»]
212L	X-ray	1.76	A	1-164	[»]
213L	X-ray	2.13	A	1-164	[»]
214L	X-ray	1.89	A	1-164	[»]
215L	X-ray	1.96	A	1-164	[»]
216L	X-ray	2.10	A/B	1-164	[»]
217L	X-ray	1.70	A	1-164	[»]
218L	X-ray	2.05	A	1-164	[»]
219L	X-ray	1.66	A	1-164	[»]
220L	X-ray	1.85	A	1-164	[»]
221L	X-ray	1.70	A	1-164	[»]
222L	X-ray	1.90	A	1-164	[»]
223L	X-ray	1.90	A	1-164	[»]
224L	X-ray	1.85	A	1-164	[»]
225L	X-ray	1.90	A	1-164	[»]
226L	X-ray	1.80	A	1-164	[»]
227L	X-ray	2.00	A	1-164	[»]
228L	X-ray	1.90	A	1-164	[»]
229L	X-ray	1.80	A	1-164	[»]
230L	X-ray	1.90	A	1-164	[»]
231L	X-ray	2.50	A	1-164	[»]
232L	X-ray	1.73	A	1-164	[»]
233L	X-ray	1.90	A	1-164	[»]
234L	X-ray	1.90	A	1-164	[»]
235L	X-ray	1.90	A	1-164	[»]
236L	X-ray	1.90	A	1-164	[»]
237L	X-ray	1.70	A	1-164	[»]
238L	X-ray	1.80	A	1-164	[»]
239L	X-ray	1.80	A	1-164	[»]
240L	X-ray	1.75	A	1-164	[»]
241L	X-ray	1.70	A	1-164	[»]
242L	X-ray	1.80	A	1-164	[»]
243L	X-ray	1.75	A	1-164	[»]
244L	X-ray	1.70	A	1-164	[»]
245L	X-ray	1.80	A	1-164	[»]
246L	X-ray	1.80	A	1-164	[»]
247L	X-ray	1.75	A	1-164	[»]
248L	X-ray	1.90	A	1-164	[»]
249L	X-ray	1.90	A	1-164	[»]
250L	X-ray	1.80	A	1-164	[»]
251L	X-ray	2.60	A	1-164	[»]
252L	X-ray	2.10	A	1-164	[»]
253L	X-ray	2.00	A	1-164	[»]
254L	X-ray	1.90	A	1-164	[»]
255L	X-ray	1.80	A	1-164	[»]
256L	X-ray	1.80	A	1-164	[»]
257L	X-ray	1.90	A	1-164	[»]
258L	X-ray	1.80	A	1-164	[»]
259L	X-ray	1.92	A	1-164	[»]
260L	X-ray	1.80	A	1-164	[»]
261L	X-ray	2.50	A	1-162	[»]
262L	X-ray	2.50	A/B	1-162	[»]
2A4T	X-ray	1.70	A	1-164	[»]
2B6T	X-ray	2.10	A	1-162	[»]
2B6W	X-ray	2.20	A	1-162	[»]
2B6X	X-ray	2.11	A	1-162	[»]
2B6Y	X-ray	2.40	A	1-162	[»]
2B6Z	X-ray	2.40	A	1-162	[»]
2B70	X-ray	2.40	A	1-162	[»]
2B72	X-ray	2.10	A	1-162	[»]
2B73	X-ray	2.15	A	1-162	[»]
2B74	X-ray	2.10	A	1-162	[»]
2B75	X-ray	2.10	A	1-162	[»]
2B7X	X-ray	3.00	A/B/C/D	1-164	[»]
2CUU	X-ray	1.75	A	1-164	[»]
2F2Q	X-ray	1.45	A	1-164	[»]
2F32	X-ray	1.80	A	1-164	[»]
2F47	X-ray	1.70	A	1-164	[»]
2HUK	X-ray	2.00	A	1-164	[»]
2HUL	X-ray	1.80	A	1-164	[»]
2HUM	X-ray	2.35	A/B	1-164	[»]
2IGC	X-ray	1.40	A	1-164	[»]
2L78	X-ray	2.00	A	1-164	[»]
2LC9	NMR	-	A	1-164	[»]
2LCB	NMR	-	A	1-164	[»]
2LZM	X-ray	1.70	A	1-164	[»]
2NTG	X-ray	1.40	A	1-164	[»]
2NTH	X-ray	1.80	A	1-164	[»]
2O4W	X-ray	1.90	A	3-164	[»]
2O79	X-ray	1.80	A	3-164	[»]
2O7A	X-ray	0.84	A	3-164	[»]
2OE4	X-ray	2.10	X	1-164	[»]
2OE7	X-ray	2.10	X	1-164	[»]
2OE9	X-ray	2.01	X	1-164	[»]
2OEA	X-ray	2.01	X	1-164	[»]
2OTY	X-ray	1.83	X	1-162	[»]
2OTZ	X-ray	2.07	X	1-162	[»]
2OU0	X-ray	1.94	X	1-162	[»]
2OU8	X-ray	1.80	A	1-164	[»]
2OU9	X-ray	1.55	A	1-164	[»]
2Q9D	X-ray	1.40	A	1-164	[»]
2Q9E	X-ray	2.10	A/B/C	1-164	[»]
2QAR	X-ray	2.40	C/F	2-162	[»]
2QB0	X-ray	2.56	B/D	2-162	[»]
2RAY	X-ray	1.80	X	1-162	[»]
2RAZ	X-ray	1.64	X	1-162	[»]
2RB0	X-ray	1.84	X	1-162	[»]
2RB1	X-ray	1.70	X	1-162	[»]
2RB2	X-ray	1.46	X	1-162	[»]
2RBN	X-ray	1.29	A	1-162	[»]
2RBO	X-ray	1.29	A	1-162	[»]
2RBP	X-ray	1.47	A	1-162	[»]
2RBQ	X-ray	1.63	A	1-162	[»]
2RBR	X-ray	1.43	A	1-162	[»]
2RBS	X-ray	1.56	A	1-162	[»]
2RH1	X-ray	2.40	A	1-162	[»]
3C7W	X-ray	1.77	A	1-164	[»]
3C7Y	X-ray	1.95	A	1-164	[»]
3C7Z	X-ray	1.67	A	1-164	[»]
3C80	X-ray	1.99	A	1-164	[»]
3C81	X-ray	1.85	A	1-164	[»]
3C82	X-ray	1.68	A	1-164	[»]
3C83	X-ray	1.84	A	1-164	[»]
3C8Q	X-ray	1.64	A	1-164	[»]
3C8R	X-ray	1.80	A	1-164	[»]
3C8S	X-ray	1.68	A	1-164	[»]
3CDO	X-ray	1.87	A/B/C/D	1-164	[»]
3CDQ	X-ray	1.68	A	1-164	[»]
3CDR	X-ray	1.70	A	1-164	[»]
3CDT	X-ray	1.63	A	1-164	[»]
3CDV	X-ray	1.73	A	1-164	[»]
3D4S	X-ray	2.80	A	2-162	[»]
3DKE	X-ray	1.25	X	1-164	[»]
3DMV	X-ray	1.65	A	1-164	[»]
3DMX	X-ray	1.80	A	1-164	[»]
3DMZ	X-ray	2.00	A	1-164	[»]
3DN0	X-ray	1.80	A	1-164	[»]
3DN1	X-ray	1.80	A	1-164	[»]
3DN2	X-ray	1.80	A	1-164	[»]
3DN3	X-ray	1.80	A	1-164	[»]
3DN4	X-ray	1.80	A	1-164	[»]
3DN6	X-ray	1.80	A	1-164	[»]
3DN8	X-ray	1.70	A	1-164	[»]
3DNA	X-ray	1.70	A	1-164	[»]
3F8V	X-ray	1.08	A	1-164	[»]
3F9L	X-ray	1.19	A	1-164	[»]
3FA0	X-ray	1.09	A	1-162	[»]
3FAD	X-ray	1.20	A	1-164	[»]
3FI5	X-ray	1.53	A/B/C/D	1-164	[»]
3G3V	X-ray	2.10	A	1-164	[»]
3G3W	X-ray	2.30	A	1-164	[»]
3G3X	X-ray	1.80	A	1-164	[»]
3GUI	X-ray	1.45	A	1-164	[»]
3GUJ	X-ray	1.60	A	1-164	[»]
3GUK	X-ray	1.85	A/B	1-164	[»]
3GUL	X-ray	2.07	A/B	1-164	[»]
3GUM	X-ray	2.24	A/B	1-164	[»]
3GUN	X-ray	1.50	A/B	1-164	[»]
3GUO	X-ray	2.16	A/B	1-164	[»]
3GUP	X-ray	1.50	A/B	1-164	[»]
3HH3	X-ray	1.25	A	1-164	[»]
3HH4	X-ray	1.25	A	1-164	[»]
3HH5	X-ray	1.25	A	1-164	[»]
3HH6	X-ray	1.25	A	1-164	[»]
3HT6	X-ray	1.59	A	1-164	[»]
3HT7	X-ray	1.70	A	1-164	[»]
3HT8	X-ray	1.60	A	1-164	[»]
3HT9	X-ray	2.02	A	1-164	[»]
3HTB	X-ray	1.81	A	1-164	[»]
3HTD	X-ray	1.40	A	1-164	[»]
3HTF	X-ray	1.85	A	1-164	[»]
3HTG	X-ray	1.26	A	1-164	[»]
3HU8	X-ray	1.80	A	1-164	[»]
3HU9	X-ray	1.46	A	1-164	[»]
3HUA	X-ray	1.40	A	1-164	[»]
3HUK	X-ray	1.29	A	1-164	[»]
3HUQ	X-ray	1.45	A	1-162	[»]
3HWL	X-ray	1.80	A	1-164	[»]
3JR6	X-ray	3.00	A/B/C/D	1-164	[»]
3K2R	X-ray	1.50	A	1-164	[»]
3L2X	X-ray	1.80	A	1-164	[»]
3L64	X-ray	1.90	A	1-164	[»]
3LZM	X-ray	1.70	A	1-164	[»]
3NY8	X-ray	2.84	A	2-162	[»]
3NY9	X-ray	2.84	A	2-162	[»]
3NYA	X-ray	3.16	A	2-162	[»]
3ODU	X-ray	2.50	A/B	2-161	[»]
3OE0	X-ray	2.90	A	2-161	[»]
3OE8	X-ray	3.10	A/B/C	2-161	[»]
3OE9	X-ray	3.10	A/B	2-161	[»]
3P0G	X-ray	3.50	A	2-161	[»]
3PBL	X-ray	2.89	A/B	2-161	[»]
3PDS	X-ray	3.50	A	2-162	[»]
3QAK	X-ray	2.71	A	2-161	[»]
3RUN	X-ray	1.40	A	1-163	[»]
3RZE	X-ray	3.10	A	2-161	[»]
3SB5	X-ray	2.46	A/B/C/D	1-162	[»]
3SB6	X-ray	2.70	A/B	1-162	[»]
3SB7	X-ray	2.70	A/B	1-162	[»]
3SB8	X-ray	2.65	A/B/C	1-162	[»]
3SB9	X-ray	2.45	A/B	1-162	[»]
3SBA	X-ray	2.75	A/B/C/D/E/F	1-162	[»]
3SBB	X-ray	1.43	C	1-162	[»]
3SN6	X-ray	3.20	R	2-161	[»]
3UON	X-ray	3.00	A	2-161	[»]
3V2W	X-ray	3.35	A	2-161	[»]
3V2Y	X-ray	2.80	A	2-161	[»]
4ARJ	X-ray	2.59	A/B	2-164	[»]
4DAJ	X-ray	3.40	A/B/C/D	1-161	[»]
4DJH	X-ray	2.90	A/B	2-161	[»]
4DKL	X-ray	2.80	A	2-161	[»]
4E97	X-ray	1.30	A/B	1-164	[»]
4EJ4	X-ray	3.40	A	2-161	[»]
4EKP	X-ray	1.64	A/B	1-164	[»]
4EKQ	X-ray	1.54	A/B	1-164	[»]
4EKR	X-ray	1.49	A/B	1-164	[»]
4EKS	X-ray	1.64	A/B	1-164	[»]
4EPI	X-ray	1.74	A	4-163	[»]
4EXM	X-ray	2.60	A/B/C/D	3-164	[»]
4GBR	X-ray	3.99	B	2-161	[»]
4GRV	X-ray	2.80	A	2-161	[»]
4LZM	X-ray	1.70	A	1-164	[»]
5LZM	X-ray	1.80	A	1-164	[»]
6LZM	X-ray	1.80	A	1-164	[»]
7LZM	X-ray	1.80	A	1-164	[»]

ProteinModelPortal

P00720.

SMR

P00720. Positions 1-164.

ModBase

Search...

Protein family/group databases

CAZy

GH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1258585.

Phylogenomic databases

ProtClustDB

CLSP2343234.

Family and domain databases

Gene3D

1.10.530.40. 1 hit.

InterPro

IPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
IPR001165. Phage_T4_Gp5_lysozyme.
[Graphical view]

Pfam

PF00959. Phage_lysozyme. 1 hit.
[Graphical view]

PRINTS

PR00684. T4LYSOZYME.

SUPFAM

SSF53955. SSF53955. 1 hit.

ProtoNet

Search...

Other

BindingDB

P00720.

ChEMBL

CHEMBL5206.

DrugBank

DB00536. Guanidine.

EvolutionaryTrace

P00720.

Entry information

Entry name

LYS_BPT4

Accession

Primary (citable) accession number: P00720
Secondary accession number(s): Q38170, Q94N07

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	May 1, 2013
This is version 132 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program