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Protein

Endolysin

Gene

E

Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.UniRule annotation1 Publication

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.UniRule annotation1 Publication

pH dependencei

Optimum pH is 7.3.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei11Proton donorUniRule annotation1 Publication1
Active sitei20NucleophileUniRule annotation2 Publications1
Binding sitei32N-acetyl-D-glucosamine; via amide nitrogenUniRule annotation1 Publication1
Binding sitei104N-acetyl-D-glucosamine; via amide nitrogenUniRule annotation1 Publication1
Sitei117Substrate-binding1 Publication1
Sitei132Substrate-binding1 Publication1

GO - Molecular functioni

  • lysozyme activity Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionAntimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase
Biological processCytolysis, Host cell lysis by virus, Virus exit from host cell

Enzyme and pathway databases

BRENDAi3.2.1.17. 732.

Protein family/group databases

CAZyiGH24. Glycoside Hydrolase Family 24.

Names & Taxonomyi

Protein namesi
Recommended name:
EndolysinUniRule annotation (EC:3.2.1.17UniRule annotation1 Publication)
Alternative name(s):
Lysis proteinUniRule annotation
LysozymeUniRule annotation
MuramidaseUniRule annotation
Gene namesi
Name:E
OrganismiEnterobacteria phage T4 (Bacteriophage T4)
Taxonomic identifieri10665 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000009087 Componenti: Genome

Subcellular locationi

  • Host cytoplasm UniRule annotation

  • Note: The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi11E → A, F, H, M or N: Almost complete loss of enzymatic activity. 1 Publication1
Mutagenesisi11E → N: Loss of 84% of enzymatic activity. 1 Publication1
Mutagenesisi11E → Q: Complete loss of activity. 1 Publication1
Mutagenesisi20D → A, N, S or T: Almost complete loss of enzymatic activity. 1 Publication1
Mutagenesisi20D → C: Nearly no effet on specific enzymatic activity. 1 Publication1
Mutagenesisi20D → E or Q: Loss of 99% of enzymatic activity. 1 Publication1
Mutagenesisi26T → E: Covalently bound substrate. 1 Publication1
Mutagenesisi30G → A: Almost complete loss of enzymatic activity. 1 Publication1
Mutagenesisi30G → F: Almost complete loss of enzymatic activity. The enzyme is destabilized by 1.5 kcal/ mol. 1 Publication1
Mutagenesisi117S → F: 10-fold decrease in enzymatic activity. 1 Publication1
Mutagenesisi117S → I: 500-fold decrease in enzymatic activity. 1 Publication1
Mutagenesisi117S → V: 50-fold decrease in enzymatic activity. 1 Publication1
Mutagenesisi132N → I: 5-fold decrease in enzymatic activity. 1 Publication1
Mutagenesisi132N → M or F: 2-fold decrease in enzymatic activity. 1 Publication1

Chemistry databases

ChEMBLiCHEMBL5206.
DrugBankiDB06934. (1R)-3-chloro-1-phenylpropan-1-ol.
DB07543. (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol.
DB03301. 2-Allyl-6-Methyl-Phenol.
DB02534. 2-Allylphenol.
DB03842. 2-Chloro-6-Methyl-Aniline.
DB02403. 2-Fluoroaniline.
DB02486. 2-Hydroxyethyl Disulfide.
DB02970. 2-Propyl-Aniline.
DB01957. 3-Chlorophenol.
DB01986. 3-Fluoro-2-Methyl-Aniline.
DB03669. 4-Fluorophenethyl Alcohol.
DB03660. 4-Iodo-L-phenylalanine.
DB01932. 5-Methylpyrrole.
DB04179. Benzofuran.
DB03345. Beta-Mercaptoethanol.
DB00536. Guanidine.
DB04532. Indole.
DB02870. N-Allyl-Aniline.
DB03255. Phenol.
DB00373. Timolol.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002181071 – 164EndolysinAdd BLAST164

Expressioni

Inductioni

Expressed late in the viral replication.

Structurei

Secondary structure

1164
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 11Combined sources9
Beta strandi14 – 19Combined sources6
Beta strandi21 – 23Combined sources3
Beta strandi25 – 28Combined sources4
Beta strandi31 – 33Combined sources3
Beta strandi35 – 37Combined sources3
Helixi39 – 50Combined sources12
Beta strandi55 – 57Combined sources3
Helixi62 – 64Combined sources3
Helixi68 – 79Combined sources12
Turni82 – 84Combined sources3
Helixi85 – 90Combined sources6
Helixi93 – 106Combined sources14
Helixi108 – 112Combined sources5
Helixi115 – 122Combined sources8
Turni123 – 125Combined sources3
Helixi126 – 133Combined sources8
Helixi137 – 141Combined sources5
Helixi143 – 155Combined sources13
Beta strandi156 – 158Combined sources3
Turni159 – 161Combined sources3
Helixi162 – 164Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
102LX-ray1.74A1-164[»]
103LX-ray1.90A1-164[»]
104LX-ray2.80A/B1-164[»]
107LX-ray1.80A1-164[»]
108LX-ray1.80A1-164[»]
109LX-ray1.85A1-164[»]
110LX-ray1.70A1-164[»]
111LX-ray1.80A1-164[»]
112LX-ray1.80A1-164[»]
113LX-ray1.80A1-164[»]
114LX-ray1.80A1-164[»]
115LX-ray1.80A1-164[»]
118LX-ray1.80A1-164[»]
119LX-ray1.65A1-164[»]
120LX-ray1.80A1-164[»]
122LX-ray1.80A1-164[»]
123LX-ray1.80A1-164[»]
125LX-ray1.85A1-164[»]
126LX-ray1.80A1-164[»]
127LX-ray1.85A1-164[»]
128LX-ray1.70A1-164[»]
129LX-ray1.70A1-164[»]
130LX-ray1.70A1-164[»]
131LX-ray1.70A1-164[»]
137LX-ray1.85A/B1-164[»]
138LX-ray1.70A1-164[»]
139LX-ray1.70A1-164[»]
140LX-ray2.10A1-164[»]
141LX-ray2.00A1-164[»]
142LX-ray2.00A1-164[»]
143LX-ray2.00A1-164[»]
144LX-ray2.10A1-164[»]
145LX-ray2.00A1-164[»]
146LX-ray1.85A1-164[»]
147LX-ray2.00A1-164[»]
148LX-ray1.90E1-164[»]
149LX-ray2.60A1-164[»]
150LX-ray2.20A/B/C/D1-164[»]
151LX-ray2.20A1-164[»]
152LX-ray2.00A1-163[»]
155LX-ray1.85A1-164[»]
156LX-ray1.80A1-164[»]
157LX-ray1.85A1-164[»]
158LX-ray1.80A1-164[»]
159LX-ray1.80A1-164[»]
160LX-ray1.80A1-164[»]
161LX-ray1.70A1-164[»]
162LX-ray1.80A1-164[»]
163LX-ray1.80A1-164[»]
164LX-ray1.80A1-164[»]
165LX-ray1.75A1-164[»]
166LX-ray1.75A1-164[»]
167LX-ray2.20A/B1-163[»]
168LX-ray2.90A/B/C/D/E1-164[»]
169LX-ray3.00A/B/C/D/E1-164[»]
170LX-ray2.60A1-164[»]
171LX-ray2.50A1-164[»]
172LX-ray1.90A1-164[»]
173LX-ray1.70A1-164[»]
174LX-ray2.30A/B1-164[»]
175LX-ray2.10A/B1-164[»]
176LX-ray2.20A/B1-164[»]
177LX-ray2.50A1-164[»]
178LX-ray2.71A1-164[»]
180LX-ray1.75A/B1-164[»]
181LX-ray1.80A1-164[»]
182LX-ray1.80A1-164[»]
183LX-ray1.80A1-164[»]
184LX-ray1.80A1-164[»]
185LX-ray1.80A1-164[»]
186LX-ray1.80A1-164[»]
187LX-ray1.80A1-164[»]
188LX-ray1.80A1-164[»]
189LX-ray2.50A1-164[»]
190LX-ray2.00A1-164[»]
191LX-ray1.95A1-164[»]
192LX-ray1.90A1-164[»]
195LX-ray1.90A1-164[»]
196LX-ray2.30A1-164[»]
197LX-ray2.10A1-164[»]
198LX-ray2.00A1-164[»]
199LX-ray1.85A1-164[»]
1B6IX-ray1.90A1-164[»]
1C60X-ray2.00A1-164[»]
1C61X-ray2.00A1-164[»]
1C62X-ray2.30A1-164[»]
1C63X-ray2.00A1-164[»]
1C64X-ray2.00A1-164[»]
1C65X-ray2.00A1-164[»]
1C66X-ray2.10A1-164[»]
1C67X-ray2.20A1-164[»]
1C68X-ray2.50A1-164[»]
1C69X-ray1.80A1-164[»]
1C6AX-ray2.10A1-164[»]
1C6BX-ray2.20A1-164[»]
1C6CX-ray2.00A1-164[»]
1C6DX-ray2.00A1-164[»]
1C6EX-ray1.90A1-164[»]
1C6FX-ray2.00A1-164[»]
1C6GX-ray1.90A1-164[»]
1C6HX-ray1.90A1-164[»]
1C6IX-ray1.90A1-164[»]
1C6JX-ray1.90A1-164[»]
1C6KX-ray1.90A1-164[»]
1C6LX-ray1.90A1-164[»]
1C6MX-ray2.10A1-164[»]
1C6NX-ray2.20A1-164[»]
1C6PX-ray1.90A1-164[»]
1C6QX-ray1.90A1-164[»]
1C6TX-ray2.00A1-164[»]
1CTWX-ray2.10A1-164[»]
1CU0X-ray2.20A1-164[»]
1CU2X-ray1.85A1-164[»]
1CU3X-ray2.12A1-164[»]
1CU5X-ray2.05A1-164[»]
1CU6X-ray2.10A1-164[»]
1CUPX-ray1.89A1-164[»]
1CUQX-ray2.05A1-164[»]
1CV0X-ray2.12A1-164[»]
1CV1X-ray2.10A1-164[»]
1CV3X-ray1.80A1-164[»]
1CV4X-ray1.90A1-164[»]
1CV5X-ray1.87A1-164[»]
1CV6X-ray1.90A1-164[»]
1CVKX-ray1.80A1-164[»]
1CX6X-ray2.01A1-164[»]
1CX7X-ray1.94A1-164[»]
1D2WX-ray1.89A1-164[»]
1D2YX-ray2.06A1-164[»]
1D3FX-ray2.05A1-164[»]
1D3JX-ray1.97A1-164[»]
1D3MX-ray2.12A1-164[»]
1D3NX-ray2.00A1-164[»]
1D9WX-ray1.70A1-164[»]
1DYAX-ray1.90A1-164[»]
1DYBX-ray1.75A1-164[»]
1DYCX-ray2.10A1-164[»]
1DYDX-ray2.10A1-164[»]
1DYEX-ray1.80A1-164[»]
1DYFX-ray1.90A1-164[»]
1DYGX-ray2.10A1-164[»]
1EPYX-ray1.85A1-164[»]
1G06X-ray1.85A1-164[»]
1G07X-ray1.70A1-164[»]
1G0GX-ray1.90A1-164[»]
1G0JX-ray1.80A1-164[»]
1G0KX-ray1.85A1-164[»]
1G0LX-ray1.80A1-164[»]
1G0MX-ray1.70A1-164[»]
1G0PX-ray1.80A1-164[»]
1G0QX-ray1.80A1-164[»]
1G1VX-ray1.90A1-164[»]
1G1WX-ray1.80A1-164[»]
1I6SX-ray1.90A1-164[»]
1JQUX-ray2.60A/B/C/D1-164[»]
1JTMX-ray1.90A1-164[»]
1JTNX-ray2.30A/B1-164[»]
1KNIX-ray1.70A1-164[»]
1KS3X-ray2.16A1-162[»]
1KW5X-ray1.75A1-162[»]
1KW7X-ray1.89A1-162[»]
1KY0X-ray1.97A1-162[»]
1KY1X-ray2.05A1-162[»]
1L00X-ray1.90A1-164[»]
1L01X-ray1.70A1-164[»]
1L02X-ray1.70A1-164[»]
1L03X-ray1.70A1-164[»]
1L04X-ray1.70A1-164[»]
1L05X-ray1.70A1-164[»]
1L06X-ray1.70A1-164[»]
1L07X-ray1.70A1-164[»]
1L08X-ray1.70A1-164[»]
1L09X-ray1.70A1-164[»]
1L0JX-ray1.98A1-162[»]
1L0KX-ray2.02A1-162[»]
1L10X-ray1.70A1-164[»]
1L11X-ray1.70A1-164[»]
1L12X-ray1.70A1-164[»]
1L13X-ray1.70A1-164[»]
1L14X-ray1.70A1-164[»]
1L15X-ray1.70A1-164[»]
1L16X-ray1.70A1-164[»]
1L17X-ray1.70A1-164[»]
1L18X-ray1.70A1-164[»]
1L19X-ray1.70A1-164[»]
1L20X-ray1.85A1-164[»]
1L21X-ray1.85A1-164[»]
1L22X-ray1.70A1-164[»]
1L23X-ray1.70A1-164[»]
1L24X-ray1.70A1-164[»]
1L25X-ray1.80A1-164[»]
1L26X-ray1.70A1-164[»]
1L27X-ray1.80A1-164[»]
1L28X-ray1.90A1-164[»]
1L29X-ray1.70A1-164[»]
1L30X-ray1.70A1-164[»]
1L31X-ray1.80A1-164[»]
1L32X-ray1.70A1-164[»]
1L33X-ray1.70A1-164[»]
1L34X-ray1.90A1-164[»]
1L35X-ray1.80A1-163[»]
1L36X-ray1.70A1-164[»]
1L37X-ray1.85A1-164[»]
1L38X-ray1.80A1-164[»]
1L39X-ray1.85A1-164[»]
1L40X-ray1.85A1-164[»]
1L41X-ray1.75A1-164[»]
1L42X-ray1.80A1-164[»]
1L43X-ray1.80A1-164[»]
1L44X-ray1.70A1-164[»]
1L45X-ray1.70A1-164[»]
1L46X-ray1.70A1-164[»]
1L47X-ray1.70A1-164[»]
1L48X-ray1.70A1-164[»]
1L49X-ray1.80A1-164[»]
1L50X-ray1.85A1-164[»]
1L51X-ray1.90A1-164[»]
1L52X-ray1.70A1-164[»]
1L53X-ray1.85A1-164[»]
1L54X-ray1.90A1-164[»]
1L55X-ray1.90A1-164[»]
1L56X-ray1.80A1-164[»]
1L57X-ray1.90A1-164[»]
1L58X-ray1.65A1-164[»]
1L59X-ray1.75A1-164[»]
1L60X-ray1.70A1-164[»]
1L61X-ray1.80A1-164[»]
1L62X-ray1.70A1-164[»]
1L63X-ray1.75A1-164[»]
1L64X-ray1.90A1-164[»]
1L65X-ray1.70A1-164[»]
1L66X-ray1.70A1-164[»]
1L67X-ray1.90A1-164[»]
1L68X-ray1.70A1-164[»]
1L69X-ray1.90A1-164[»]
1L70X-ray1.90A1-164[»]
1L71X-ray1.85A1-164[»]
1L72X-ray1.85A1-164[»]
1L73X-ray1.85A1-164[»]
1L74X-ray1.70A1-164[»]
1L75X-ray1.90A1-164[»]
1L76X-ray1.90A1-164[»]
1L77X-ray2.05A1-164[»]
1L79X-ray1.90A1-164[»]
1L80X-ray1.80A1-164[»]
1L81X-ray2.00A1-164[»]
1L82X-ray2.10A1-164[»]
1L83X-ray1.70A1-164[»]
1L84X-ray1.90A1-164[»]
1L85X-ray2.00A1-164[»]
1L86X-ray1.80A1-164[»]
1L87X-ray1.80A1-164[»]
1L88X-ray1.85A1-164[»]
1L89X-ray1.90A1-164[»]
1L90X-ray1.75A1-164[»]
1L91X-ray1.80A1-164[»]
1L92X-ray1.70A1-164[»]
1L93X-ray1.80A1-164[»]
1L94X-ray1.80A1-164[»]
1L95X-ray2.00A1-164[»]
1L96X-ray2.00A1-164[»]
1L97X-ray2.00A/B1-164[»]
1L98X-ray1.80A1-164[»]
1L99X-ray1.95A1-164[»]
1LGUX-ray1.90A1-164[»]
1LGWX-ray1.85A1-164[»]
1LGXX-ray1.90A1-164[»]
1LI2X-ray2.00A1-164[»]
1LI3X-ray1.85A1-164[»]
1LI6X-ray2.00A1-164[»]
1LLHX-ray1.80A1-164[»]
1LPYX-ray1.65A1-164[»]
1LW9X-ray1.45A1-164[»]
1LWGX-ray1.70A1-164[»]
1LWKX-ray2.10A1-164[»]
1LYDX-ray2.00A1-164[»]
1LYEX-ray1.80A1-164[»]
1LYFX-ray1.80A1-164[»]
1LYGX-ray1.80A1-164[»]
1LYHX-ray1.70A1-164[»]
1LYIX-ray2.00A1-164[»]
1LYJX-ray1.80A1-164[»]
1NHBX-ray1.80A1-164[»]
1OV5X-ray2.10A1-164[»]
1OV7X-ray2.00A1-164[»]
1OVHX-ray1.95A1-164[»]
1OVJX-ray2.00A1-164[»]
1OVKX-ray2.10A1-164[»]
1OWYX-ray1.90A1-164[»]
1OWZX-ray1.90A1-164[»]
1OYUX-ray2.50A/B1-164[»]
1P2LX-ray1.58A1-164[»]
1P2RX-ray1.58A1-164[»]
1P36X-ray1.45A1-164[»]
1P37X-ray1.57A1-164[»]
1P3NX-ray1.55A1-164[»]
1P46X-ray1.67A1-164[»]
1P56X-ray1.80A1-162[»]
1P5CX-ray2.50A/B/C/D12-163[»]
1P64X-ray1.62A1-164[»]
1P6YX-ray1.54A1-164[»]
1P7SX-ray1.50A1-164[»]
1PQDX-ray1.65A1-164[»]
1PQIX-ray1.57A1-164[»]
1PQJX-ray1.90A1-164[»]
1PQKX-ray2.00A/B/C1-164[»]
1PQMX-ray1.52A1-164[»]
1PQOX-ray1.65A1-164[»]
1QS5X-ray2.50A1-162[»]
1QS9X-ray1.85A1-162[»]
1QSBX-ray1.80A1-162[»]
1QSQX-ray1.90A1-164[»]
1QT3X-ray1.85A1-164[»]
1QT4X-ray2.10A1-164[»]
1QT5X-ray1.80A1-164[»]
1QT6X-ray1.90A1-164[»]
1QT7X-ray1.80A1-164[»]
1QT8X-ray1.90A1-164[»]
1QTBX-ray1.90A1-162[»]
1QTCX-ray2.50A1-162[»]
1QTDX-ray2.50A1-162[»]
1QTHX-ray1.90A/B1-164[»]
1QTVX-ray2.30A1-164[»]
1QTZX-ray2.00A1-164[»]
1QUDX-ray1.75A1-162[»]
1QUGX-ray1.90A1-162[»]
1QUHX-ray1.85A1-162[»]
1QUOX-ray1.90A1-162[»]
1SSWX-ray2.13A1-164[»]
1SSYX-ray2.40A/B1-164[»]
1SWYX-ray1.06A1-164[»]
1SWZX-ray1.06A1-164[»]
1SX2X-ray1.06A1-164[»]
1SX7X-ray1.06A1-164[»]
1T6HX-ray2.01A1-164[»]
1T8AX-ray2.00A1-164[»]
1T8FX-ray2.15A1-164[»]
1T8GX-ray1.80A1-164[»]
1T97X-ray2.70A/B1-164[»]
1TLAX-ray2.00A1-164[»]
1XEPX-ray1.55A1-164[»]
1ZURX-ray1.60A1-164[»]
1ZWNX-ray1.80A1-164[»]
1ZYTX-ray1.70A1-164[»]
200LX-ray1.95A1-164[»]
201LX-ray2.00A/B1-164[»]
205LX-ray2.10A1-164[»]
206LX-ray1.75A1-164[»]
209LX-ray2.70A1-164[»]
210LX-ray1.89A1-164[»]
211LX-ray1.70A1-164[»]
212LX-ray1.76A1-164[»]
213LX-ray2.13A1-164[»]
214LX-ray1.89A1-164[»]
215LX-ray1.96A1-164[»]
216LX-ray2.10A/B1-164[»]
217LX-ray1.70A1-164[»]
218LX-ray2.05A1-164[»]
219LX-ray1.66A1-164[»]
220LX-ray1.85A1-164[»]
221LX-ray1.70A1-164[»]
222LX-ray1.90A1-164[»]
223LX-ray1.90A1-164[»]
224LX-ray1.85A1-164[»]
225LX-ray1.90A1-164[»]
226LX-ray1.80A1-164[»]
227LX-ray2.00A1-164[»]
228LX-ray1.90A1-164[»]
229LX-ray1.80A1-164[»]
230LX-ray1.90A1-164[»]
231LX-ray2.50A1-164[»]
232LX-ray1.73A1-164[»]
233LX-ray1.90A1-164[»]
234LX-ray1.90A1-164[»]
235LX-ray1.90A1-164[»]
236LX-ray1.90A1-164[»]
237LX-ray1.70A1-164[»]
238LX-ray1.80A1-164[»]
239LX-ray1.80A1-164[»]
240LX-ray1.75A1-164[»]
241LX-ray1.70A1-164[»]
242LX-ray1.80A1-164[»]
243LX-ray1.75A1-164[»]
244LX-ray1.70A1-164[»]
245LX-ray1.80A1-164[»]
246LX-ray1.80A1-164[»]
247LX-ray1.75A1-164[»]
248LX-ray1.90A1-164[»]
249LX-ray1.90A1-164[»]
250LX-ray1.80A1-164[»]
251LX-ray2.60A1-164[»]
252LX-ray2.10A1-164[»]
253LX-ray2.00A1-164[»]
254LX-ray1.90A1-164[»]
255LX-ray1.80A1-164[»]
256LX-ray1.80A1-164[»]
257LX-ray1.90A1-164[»]
258LX-ray1.80A1-164[»]
259LX-ray1.92A1-164[»]
260LX-ray1.80A1-164[»]
261LX-ray2.50A1-162[»]
262LX-ray2.50A/B1-162[»]
2A4TX-ray1.70A1-164[»]
2B6TX-ray2.10A1-162[»]
2B6WX-ray2.20A1-162[»]
2B6XX-ray2.11A1-162[»]
2B6YX-ray2.40A1-162[»]
2B6ZX-ray2.40A1-162[»]
2B70X-ray2.40A1-162[»]
2B72X-ray2.10A1-162[»]
2B73X-ray2.15A1-162[»]
2B74X-ray2.10A1-162[»]
2B75X-ray2.10A1-162[»]
2B7XX-ray3.00A/B/C/D1-164[»]
2CUUX-ray1.75A1-164[»]
2F2QX-ray1.45A1-164[»]
2F32X-ray1.80A1-164[»]
2F47X-ray1.70A1-164[»]
2HUKX-ray2.00A1-164[»]
2HULX-ray1.80A1-164[»]
2HUMX-ray2.35A/B1-164[»]
2IGCX-ray1.40A1-164[»]
2L78X-ray2.00A1-164[»]
2LC9NMR-A1-164[»]
2LCBNMR-A1-164[»]
2LZMX-ray1.70A1-164[»]
2NTGX-ray1.40A1-164[»]
2NTHX-ray1.80A1-164[»]
2O4WX-ray1.90A13-164[»]
2O79X-ray1.80A1-164[»]
2O7AX-ray0.84A60-164[»]
2OE4X-ray2.10X1-164[»]
2OE7X-ray2.10X1-164[»]
2OE9X-ray2.01X1-164[»]
2OEAX-ray2.01X1-164[»]
2OTYX-ray1.83X1-162[»]
2OTZX-ray2.07X1-162[»]
2OU0X-ray1.94X1-162[»]
2OU8X-ray1.80A1-164[»]
2OU9X-ray1.55A1-164[»]
2Q9DX-ray1.40A1-164[»]
2Q9EX-ray2.10A/B/C1-164[»]
2QARX-ray2.40C/F2-162[»]
2QB0X-ray2.56B/D2-162[»]
2RAYX-ray1.80X1-162[»]
2RAZX-ray1.64X1-162[»]
2RB0X-ray1.84X1-162[»]
2RB1X-ray1.70X1-162[»]
2RB2X-ray1.46X1-162[»]
2RBNX-ray1.29A1-162[»]
2RBOX-ray1.29A1-162[»]
2RBPX-ray1.47A1-162[»]
2RBQX-ray1.63A1-162[»]
2RBRX-ray1.43A1-162[»]
2RBSX-ray1.56A1-162[»]
2RH1X-ray2.40A2-161[»]
3C7WX-ray1.77A1-164[»]
3C7YX-ray1.95A1-164[»]
3C7ZX-ray1.67A1-164[»]
3C80X-ray1.99A1-164[»]
3C81X-ray1.85A1-164[»]
3C82X-ray1.68A1-164[»]
3C83X-ray1.84A1-164[»]
3C8QX-ray1.64A1-164[»]
3C8RX-ray1.80A1-164[»]
3C8SX-ray1.68A1-164[»]
3CDOX-ray1.87A/B/C/D1-164[»]
3CDQX-ray1.68A1-164[»]
3CDRX-ray1.70A1-164[»]
3CDTX-ray1.63A1-164[»]
3CDVX-ray1.73A1-164[»]
3D4SX-ray2.80A2-161[»]
3DKEX-ray1.25X1-164[»]
3DMVX-ray1.65A1-164[»]
3DMXX-ray1.80A1-164[»]
3DMZX-ray2.00A1-164[»]
3DN0X-ray1.80A1-164[»]
3DN1X-ray1.80A1-164[»]
3DN2X-ray1.80A1-164[»]
3DN3X-ray1.80A1-164[»]
3DN4X-ray1.80A1-164[»]
3DN6X-ray1.80A1-164[»]
3DN8X-ray1.70A1-164[»]
3DNAX-ray1.70A1-164[»]
3EMLX-ray2.60A2-161[»]
3F8VX-ray1.08A1-164[»]
3F9LX-ray1.19A1-164[»]
3FA0X-ray1.09A1-162[»]
3FADX-ray1.20A1-164[»]
3FI5X-ray1.53A/B/C/D1-164[»]
3G3VX-ray2.10A1-164[»]
3G3WX-ray2.30A1-164[»]
3G3XX-ray1.80A1-164[»]
3GUIX-ray1.45A1-164[»]
3GUJX-ray1.60A1-164[»]
3GUKX-ray1.85A/B1-164[»]
3GULX-ray2.07A/B1-164[»]
3GUMX-ray2.24A/B1-164[»]
3GUNX-ray1.50A/B1-164[»]
3GUOX-ray2.16A/B1-164[»]
3GUPX-ray1.50A/B1-164[»]
3HH3X-ray1.25A1-164[»]
3HH4X-ray1.25A1-164[»]
3HH5X-ray1.25A1-164[»]
3HH6X-ray1.25A1-164[»]
3HT6X-ray1.59A1-164[»]
3HT7X-ray1.70A1-164[»]
3HT8X-ray1.60A1-164[»]
3HT9X-ray2.02A1-164[»]
3HTBX-ray1.81A1-164[»]
3HTDX-ray1.40A1-164[»]
3HTFX-ray1.85A1-164[»]
3HTGX-ray1.26A1-164[»]
3HU8X-ray1.80A1-164[»]
3HU9X-ray1.46A1-164[»]
3HUAX-ray1.40A1-164[»]
3HUKX-ray1.29A1-164[»]
3HUQX-ray1.45A1-162[»]
3HWLX-ray1.80A1-164[»]
3JR6X-ray3.00A/B/C/D1-164[»]
3K2RX-ray1.50A1-164[»]
3L2XX-ray1.80A1-164[»]
3L64X-ray1.90A1-164[»]
3LZMX-ray1.70A1-164[»]
3NY8X-ray2.84A2-161[»]
3NY9X-ray2.84A2-161[»]
3NYAX-ray3.16A2-161[»]
3ODUX-ray2.50A/B2-161[»]
3OE0X-ray2.90A2-161[»]
3OE6X-ray3.20A2-161[»]
3OE8X-ray3.10A/B/C2-161[»]
3OE9X-ray3.10A/B2-161[»]
3P0GX-ray3.50A2-161[»]
3PBLX-ray2.89A/B2-161[»]
3PDSX-ray3.50A2-162[»]
3QAKX-ray2.71A2-161[»]
3RUNX-ray1.40A1-164[»]
3RZEX-ray3.10A2-161[»]
3SB5X-ray2.46A/B/C/D1-162[»]
3SB6X-ray2.70A/B1-162[»]
3SB7X-ray2.70A/B1-162[»]
3SB8X-ray2.65A/B/C1-162[»]
3SB9X-ray2.45A/B1-162[»]
3SBAX-ray2.75A/B/C/D/E/F1-162[»]
3SBBX-ray1.43C1-162[»]
3SN6X-ray3.20R2-161[»]
3UONX-ray3.00A2-161[»]
3V2WX-ray3.35A2-161[»]
3V2YX-ray2.80A2-161[»]
3VW7X-ray2.20A2-161[»]
4ARJX-ray2.59A/B2-164[»]
4DAJX-ray3.40A/B/C/D1-161[»]
4DJHX-ray2.90A/B2-161[»]
4DKLX-ray2.80A2-161[»]
4E97X-ray1.30A/B1-164[»]
4EJ4X-ray3.40A2-161[»]
4EKPX-ray1.64A/B1-164[»]
4EKQX-ray1.54A/B1-164[»]
4EKRX-ray1.49A/B1-164[»]
4EKSX-ray1.64A/B1-164[»]
4EPIX-ray1.74A3-164[»]
4EXMX-ray2.60A/B/C/D3-164[»]
4GBRX-ray3.99B2-161[»]
4GRVX-ray2.80A2-161[»]
4HTTX-ray6.80A/B1-164[»]
4I7JX-ray1.67A/B1-164[»]
4I7KX-ray1.72A/B1-164[»]
4I7LX-ray1.52A/B1-164[»]
4I7MX-ray1.48A/B1-164[»]
4I7NX-ray1.58A/B1-164[»]
4I7OX-ray1.73A/B1-164[»]
4I7PX-ray1.60A/B1-164[»]
4I7QX-ray1.58A/B1-164[»]
4I7RX-ray1.52A/B1-164[»]
4I7SX-ray1.69A/B1-164[»]
4I7TX-ray1.55A/B1-164[»]
4IAPX-ray2.30A/B2-161[»]
4K5YX-ray2.98A/B/C2-161[»]
4LDEX-ray2.79A2-161[»]
4LDLX-ray3.10A2-161[»]
4LDOX-ray3.20A2-161[»]
4LZMX-ray1.70A1-164[»]
4N9NX-ray2.90A/B2-161[»]
4OO9X-ray2.60A2-161[»]
4PHUX-ray2.33A2-161[»]
4RWSX-ray3.10A2-161[»]
4S0WX-ray2.12A/B1-164[»]
4TN3X-ray3.20A/B1-164[»]
4U14X-ray3.57A1-161[»]
4W51X-ray1.45A1-164[»]
4W52X-ray1.50A1-164[»]
4W53X-ray1.56A1-164[»]
4W54X-ray1.79A1-164[»]
4W55X-ray1.64A1-164[»]
4W56X-ray1.63A1-164[»]
4W57X-ray1.68A1-164[»]
4W58X-ray1.80A1-164[»]
4W59X-ray1.39A1-164[»]
4W8FX-ray3.54A/B2-161[»]
4WTVX-ray1.90A/B2-164[»]
4XEEX-ray2.90A2-161[»]
4XESX-ray2.60A2-161[»]
4YX7X-ray2.00C/F2-164[»]
4YXAX-ray2.35C/F2-164[»]
4YXCX-ray2.30A2-161[»]
4ZWJX-ray3.30A/B/C/D2-161[»]
5B2GX-ray3.50A/C/E/G2-162[»]
5CGCX-ray3.10A2-161[»]
5CGDX-ray2.60A2-161[»]
5CXVX-ray2.70A2-161[»]
5D5AX-ray2.48A2-161[»]
5D5BX-ray3.80A2-161[»]
5D6LX-ray3.20A2-162[»]
5DGYX-ray7.70A/B/C/D2-161[»]
5DSGX-ray2.60A/B2-11[»]
A/B61-161[»]
5EE7X-ray2.50A2-160[»]
5EUTX-ray2.80A2-163[»]
5EWXX-ray2.60A/B1-35[»]
A/B38-164[»]
5G27X-ray1.61A1-164[»]
5GLHX-ray2.80A2-163[»]
5GLIX-ray2.50A61-163[»]
5I14X-ray1.75A/B1-164[»]
5JDTX-ray1.00A1-164[»]
5JEAX-ray2.65K1-164[»]
5JGNX-ray1.53A1-164[»]
5JGRX-ray1.46A1-164[»]
5JGUX-ray1.47A1-164[»]
5JGVX-ray1.73A1-164[»]
5JGXX-ray1.53A1-164[»]
5JGZX-ray1.53A1-164[»]
5JQHX-ray3.20A/B2-161[»]
5JWSX-ray1.65A1-164[»]
5JWTX-ray1.41A1-164[»]
5JWUX-ray1.70A1-164[»]
5JWVX-ray1.30A1-164[»]
5JWWX-ray1.47A1-164[»]
5KGRX-ray1.47A1-164[»]
5KHZX-ray1.49A1-164[»]
5KI1X-ray1.46A1-164[»]
5KI2X-ray1.50A1-164[»]
5KI3X-ray1.65A1-164[»]
5KI8X-ray1.55A1-164[»]
5KIGX-ray1.50A1-164[»]
5KIIX-ray1.56A1-164[»]
5KIMX-ray1.50A1-164[»]
5KIOX-ray1.63A1-164[»]
5LWOX-ray1.18A1-164[»]
5LZMX-ray1.80A1-164[»]
5T04X-ray3.30A2-161[»]
5T1AX-ray2.81A3-163[»]
6LZMX-ray1.80A1-164[»]
7LZMX-ray1.80A1-164[»]
SMRiP00720.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP00720.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 24 family.UniRule annotation

Phylogenomic databases

KOiK01185.
OrthoDBiVOG090000CE.

Family and domain databases

Gene3Di1.10.530.40. 1 hit.
HAMAPiMF_04110. ENDOLYSIN_T4. 1 hit.
InterProiView protein in InterPro
IPR034690. Endolysin_T4_type.
IPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
IPR001165. T4-type_lysozyme.
PfamiView protein in Pfam
PF00959. Phage_lysozyme. 1 hit.
PRINTSiPR00684. T4LYSOZYME.
SUPFAMiSSF53955. SSF53955. 1 hit.

Sequencei

Sequence statusi: Complete.

P00720-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIFEMLRID ERLRLKIYKD TEGYYTIGIG HLLTKSPSLN AAKSELDKAI
60 70 80 90 100
GRNCNGVITK DEAEKLFNQD VDAAVRGILR NAKLKPVYDS LDAVRRCALI
110 120 130 140 150
NMVFQMGETG VAGFTNSLRM LQQKRWDEAA VNLAKSIWYN QTPNRAKRVI
160
TTFRTGTWDA YKNL
Length:164
Mass (Da):18,692
Last modified:May 14, 2014 - v2
Checksum:i02D568CC8FC81CF1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12R → G AA sequence (PubMed:5470817).Curated1
Sequence conflicti137I → R AA sequence (PubMed:5470817).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04567 Genomic DNA. Translation: CAA28212.1.
AF158101 Genomic DNA. Translation: AAD42568.1.
PIRiA92896. LZBPT4.
RefSeqiNP_049736.1. NC_000866.4.

Genome annotation databases

GeneIDi1258585.
KEGGivg:1258585.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04567 Genomic DNA. Translation: CAA28212.1.
AF158101 Genomic DNA. Translation: AAD42568.1.
PIRiA92896. LZBPT4.
RefSeqiNP_049736.1. NC_000866.4.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
102LX-ray1.74A1-164[»]
103LX-ray1.90A1-164[»]
104LX-ray2.80A/B1-164[»]
107LX-ray1.80A1-164[»]
108LX-ray1.80A1-164[»]
109LX-ray1.85A1-164[»]
110LX-ray1.70A1-164[»]
111LX-ray1.80A1-164[»]
112LX-ray1.80A1-164[»]
113LX-ray1.80A1-164[»]
114LX-ray1.80A1-164[»]
115LX-ray1.80A1-164[»]
118LX-ray1.80A1-164[»]
119LX-ray1.65A1-164[»]
120LX-ray1.80A1-164[»]
122LX-ray1.80A1-164[»]
123LX-ray1.80A1-164[»]
125LX-ray1.85A1-164[»]
126LX-ray1.80A1-164[»]
127LX-ray1.85A1-164[»]
128LX-ray1.70A1-164[»]
129LX-ray1.70A1-164[»]
130LX-ray1.70A1-164[»]
131LX-ray1.70A1-164[»]
137LX-ray1.85A/B1-164[»]
138LX-ray1.70A1-164[»]
139LX-ray1.70A1-164[»]
140LX-ray2.10A1-164[»]
141LX-ray2.00A1-164[»]
142LX-ray2.00A1-164[»]
143LX-ray2.00A1-164[»]
144LX-ray2.10A1-164[»]
145LX-ray2.00A1-164[»]
146LX-ray1.85A1-164[»]
147LX-ray2.00A1-164[»]
148LX-ray1.90E1-164[»]
149LX-ray2.60A1-164[»]
150LX-ray2.20A/B/C/D1-164[»]
151LX-ray2.20A1-164[»]
152LX-ray2.00A1-163[»]
155LX-ray1.85A1-164[»]
156LX-ray1.80A1-164[»]
157LX-ray1.85A1-164[»]
158LX-ray1.80A1-164[»]
159LX-ray1.80A1-164[»]
160LX-ray1.80A1-164[»]
161LX-ray1.70A1-164[»]
162LX-ray1.80A1-164[»]
163LX-ray1.80A1-164[»]
164LX-ray1.80A1-164[»]
165LX-ray1.75A1-164[»]
166LX-ray1.75A1-164[»]
167LX-ray2.20A/B1-163[»]
168LX-ray2.90A/B/C/D/E1-164[»]
169LX-ray3.00A/B/C/D/E1-164[»]
170LX-ray2.60A1-164[»]
171LX-ray2.50A1-164[»]
172LX-ray1.90A1-164[»]
173LX-ray1.70A1-164[»]
174LX-ray2.30A/B1-164[»]
175LX-ray2.10A/B1-164[»]
176LX-ray2.20A/B1-164[»]
177LX-ray2.50A1-164[»]
178LX-ray2.71A1-164[»]
180LX-ray1.75A/B1-164[»]
181LX-ray1.80A1-164[»]
182LX-ray1.80A1-164[»]
183LX-ray1.80A1-164[»]
184LX-ray1.80A1-164[»]
185LX-ray1.80A1-164[»]
186LX-ray1.80A1-164[»]
187LX-ray1.80A1-164[»]
188LX-ray1.80A1-164[»]
189LX-ray2.50A1-164[»]
190LX-ray2.00A1-164[»]
191LX-ray1.95A1-164[»]
192LX-ray1.90A1-164[»]
195LX-ray1.90A1-164[»]
196LX-ray2.30A1-164[»]
197LX-ray2.10A1-164[»]
198LX-ray2.00A1-164[»]
199LX-ray1.85A1-164[»]
1B6IX-ray1.90A1-164[»]
1C60X-ray2.00A1-164[»]
1C61X-ray2.00A1-164[»]
1C62X-ray2.30A1-164[»]
1C63X-ray2.00A1-164[»]
1C64X-ray2.00A1-164[»]
1C65X-ray2.00A1-164[»]
1C66X-ray2.10A1-164[»]
1C67X-ray2.20A1-164[»]
1C68X-ray2.50A1-164[»]
1C69X-ray1.80A1-164[»]
1C6AX-ray2.10A1-164[»]
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3SB8X-ray2.65A/B/C1-162[»]
3SB9X-ray2.45A/B1-162[»]
3SBAX-ray2.75A/B/C/D/E/F1-162[»]
3SBBX-ray1.43C1-162[»]
3SN6X-ray3.20R2-161[»]
3UONX-ray3.00A2-161[»]
3V2WX-ray3.35A2-161[»]
3V2YX-ray2.80A2-161[»]
3VW7X-ray2.20A2-161[»]
4ARJX-ray2.59A/B2-164[»]
4DAJX-ray3.40A/B/C/D1-161[»]
4DJHX-ray2.90A/B2-161[»]
4DKLX-ray2.80A2-161[»]
4E97X-ray1.30A/B1-164[»]
4EJ4X-ray3.40A2-161[»]
4EKPX-ray1.64A/B1-164[»]
4EKQX-ray1.54A/B1-164[»]
4EKRX-ray1.49A/B1-164[»]
4EKSX-ray1.64A/B1-164[»]
4EPIX-ray1.74A3-164[»]
4EXMX-ray2.60A/B/C/D3-164[»]
4GBRX-ray3.99B2-161[»]
4GRVX-ray2.80A2-161[»]
4HTTX-ray6.80A/B1-164[»]
4I7JX-ray1.67A/B1-164[»]
4I7KX-ray1.72A/B1-164[»]
4I7LX-ray1.52A/B1-164[»]
4I7MX-ray1.48A/B1-164[»]
4I7NX-ray1.58A/B1-164[»]
4I7OX-ray1.73A/B1-164[»]
4I7PX-ray1.60A/B1-164[»]
4I7QX-ray1.58A/B1-164[»]
4I7RX-ray1.52A/B1-164[»]
4I7SX-ray1.69A/B1-164[»]
4I7TX-ray1.55A/B1-164[»]
4IAPX-ray2.30A/B2-161[»]
4K5YX-ray2.98A/B/C2-161[»]
4LDEX-ray2.79A2-161[»]
4LDLX-ray3.10A2-161[»]
4LDOX-ray3.20A2-161[»]
4LZMX-ray1.70A1-164[»]
4N9NX-ray2.90A/B2-161[»]
4OO9X-ray2.60A2-161[»]
4PHUX-ray2.33A2-161[»]
4RWSX-ray3.10A2-161[»]
4S0WX-ray2.12A/B1-164[»]
4TN3X-ray3.20A/B1-164[»]
4U14X-ray3.57A1-161[»]
4W51X-ray1.45A1-164[»]
4W52X-ray1.50A1-164[»]
4W53X-ray1.56A1-164[»]
4W54X-ray1.79A1-164[»]
4W55X-ray1.64A1-164[»]
4W56X-ray1.63A1-164[»]
4W57X-ray1.68A1-164[»]
4W58X-ray1.80A1-164[»]
4W59X-ray1.39A1-164[»]
4W8FX-ray3.54A/B2-161[»]
4WTVX-ray1.90A/B2-164[»]
4XEEX-ray2.90A2-161[»]
4XESX-ray2.60A2-161[»]
4YX7X-ray2.00C/F2-164[»]
4YXAX-ray2.35C/F2-164[»]
4YXCX-ray2.30A2-161[»]
4ZWJX-ray3.30A/B/C/D2-161[»]
5B2GX-ray3.50A/C/E/G2-162[»]
5CGCX-ray3.10A2-161[»]
5CGDX-ray2.60A2-161[»]
5CXVX-ray2.70A2-161[»]
5D5AX-ray2.48A2-161[»]
5D5BX-ray3.80A2-161[»]
5D6LX-ray3.20A2-162[»]
5DGYX-ray7.70A/B/C/D2-161[»]
5DSGX-ray2.60A/B2-11[»]
A/B61-161[»]
5EE7X-ray2.50A2-160[»]
5EUTX-ray2.80A2-163[»]
5EWXX-ray2.60A/B1-35[»]
A/B38-164[»]
5G27X-ray1.61A1-164[»]
5GLHX-ray2.80A2-163[»]
5GLIX-ray2.50A61-163[»]
5I14X-ray1.75A/B1-164[»]
5JDTX-ray1.00A1-164[»]
5JEAX-ray2.65K1-164[»]
5JGNX-ray1.53A1-164[»]
5JGRX-ray1.46A1-164[»]
5JGUX-ray1.47A1-164[»]
5JGVX-ray1.73A1-164[»]
5JGXX-ray1.53A1-164[»]
5JGZX-ray1.53A1-164[»]
5JQHX-ray3.20A/B2-161[»]
5JWSX-ray1.65A1-164[»]
5JWTX-ray1.41A1-164[»]
5JWUX-ray1.70A1-164[»]
5JWVX-ray1.30A1-164[»]
5JWWX-ray1.47A1-164[»]
5KGRX-ray1.47A1-164[»]
5KHZX-ray1.49A1-164[»]
5KI1X-ray1.46A1-164[»]
5KI2X-ray1.50A1-164[»]
5KI3X-ray1.65A1-164[»]
5KI8X-ray1.55A1-164[»]
5KIGX-ray1.50A1-164[»]
5KIIX-ray1.56A1-164[»]
5KIMX-ray1.50A1-164[»]
5KIOX-ray1.63A1-164[»]
5LWOX-ray1.18A1-164[»]
5LZMX-ray1.80A1-164[»]
5T04X-ray3.30A2-161[»]
5T1AX-ray2.81A3-163[»]
6LZMX-ray1.80A1-164[»]
7LZMX-ray1.80A1-164[»]
SMRiP00720.
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

ChEMBLiCHEMBL5206.
DrugBankiDB06934. (1R)-3-chloro-1-phenylpropan-1-ol.
DB07543. (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol.
DB03301. 2-Allyl-6-Methyl-Phenol.
DB02534. 2-Allylphenol.
DB03842. 2-Chloro-6-Methyl-Aniline.
DB02403. 2-Fluoroaniline.
DB02486. 2-Hydroxyethyl Disulfide.
DB02970. 2-Propyl-Aniline.
DB01957. 3-Chlorophenol.
DB01986. 3-Fluoro-2-Methyl-Aniline.
DB03669. 4-Fluorophenethyl Alcohol.
DB03660. 4-Iodo-L-phenylalanine.
DB01932. 5-Methylpyrrole.
DB04179. Benzofuran.
DB03345. Beta-Mercaptoethanol.
DB00536. Guanidine.
DB04532. Indole.
DB02870. N-Allyl-Aniline.
DB03255. Phenol.
DB00373. Timolol.

Protein family/group databases

CAZyiGH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1258585.
KEGGivg:1258585.

Phylogenomic databases

KOiK01185.
OrthoDBiVOG090000CE.

Enzyme and pathway databases

BRENDAi3.2.1.17. 732.

Miscellaneous databases

EvolutionaryTraceiP00720.

Family and domain databases

Gene3Di1.10.530.40. 1 hit.
HAMAPiMF_04110. ENDOLYSIN_T4. 1 hit.
InterProiView protein in InterPro
IPR034690. Endolysin_T4_type.
IPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
IPR001165. T4-type_lysozyme.
PfamiView protein in Pfam
PF00959. Phage_lysozyme. 1 hit.
PRINTSiPR00684. T4LYSOZYME.
SUPFAMiSSF53955. SSF53955. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiENLYS_BPT4
AccessioniPrimary (citable) accession number: P00720
Secondary accession number(s): Q38170, Q94N07
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: May 14, 2014
Last modified: June 7, 2017
This is version 165 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.