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P00718 (LYG_ANSAN) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lysozyme g

EC=3.2.1.17
Alternative name(s):
1,4-beta-N-acetylmuramidase
Goose-type lysozyme
OrganismAnser anser anser (Western graylag goose)
Taxonomic identifier8844 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeAnseriformesAnatidaeAnser

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Subcellular location

Secreted.

Miscellaneous

Shows preference for N-acetylmuramic acid residues that are substituted with a peptide moiety. It acts only as a glycanohydrolase.

Sequence similarities

Belongs to the glycosyl hydrolase 23 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Lysozyme g
PRO_0000193513

Sites

Active site731
Active site861

Amino acid modifications

Disulfide bond4 ↔ 60
Disulfide bond18 ↔ 29

Secondary structure

............................... 185
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P00718 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 0B2F0C9B2A66C324

FASTA18520,373
        10         20         30         40         50         60 
RTDCYGNVNR IDTTGASCKT AKPEGLSYCG VSASKKIAER DLQAMDRYKT IIKKVGEKLC 

        70         80         90        100        110        120 
VEPAVIAGII SRESHAGKVL KNGWGDRGNG FGLMQVDKRS HKPQGTWNGE VHITQGTTIL 

       130        140        150        160        170        180 
INFIKTIQKK FPSWTKDQQL KGGISAYNAG AGNVRSYARM DIGTTHDDYA NDVVARAQYY 


KQHGY 

« Hide

References

[1]"Complete amino acid sequence of Embden goose (Anser anser) egg-white lysozyme."
Simpson R.J., Morgan F.J.
Biochim. Biophys. Acta 744:349-351(1983)
Cited for: PROTEIN SEQUENCE.
Strain: Embden breed.
Tissue: Egg white.
[2]"Goose lysozyme structure: an evolutionary link between hen and bacteriophage lysozymes?"
Gruetter M.G., Weaver L.H., Matthews B.W.
Nature 303:828-831(1983) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS).
[3]"The refined structures of goose lysozyme and its complex with a bound trisaccharide show that the 'goose-type' lysozymes lack a catalytic aspartate residue."
Weaver L.H., Gruetter M.G., Matthews B.W.
J. Mol. Biol. 245:54-68(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS).

Cross-references

Sequence databases

PIRLZGSG. A00873.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
153LX-ray1.60A1-185[»]
154LX-ray1.60A1-185[»]
ProteinModelPortalP00718.
SMRP00718. Positions 1-185.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH23. Glycoside Hydrolase Family 23.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG006299.

Family and domain databases

InterProIPR002152. Glyco_hydro_23.
IPR023346. Lysozyme-like_dom.
IPR008258. TGlycosylase-like_SLT.
[Graphical view]
PfamPF01464. SLT. 1 hit.
[Graphical view]
PIRSFPIRSF001065. Lysozyme_g. 1 hit.
PRINTSPR00749. LYSOZYMEG.
SUPFAMSSF53955. SSF53955. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP00718.

Entry information

Entry nameLYG_ANSAN
AccessionPrimary (citable) accession number: P00718
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: October 16, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries