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P00717 (LYG_CYGAT) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lysozyme g

EC=3.2.1.17
Alternative name(s):
1,4-beta-N-acetylmuramidase
Goose-type lysozyme
OrganismCygnus atratus (Black swan) (Anas atrata)
Taxonomic identifier8868 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeAnseriformesAnatidaeCygnus

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Subcellular location

Secreted.

Miscellaneous

Shows preference for N-acetylmuramic acid residues that are substituted with a peptide moiety. It acts only as a glycanohydrolase.

Sequence similarities

Belongs to the glycosyl hydrolase 23 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Lysozyme g
PRO_0000193515

Sites

Active site731 By similarity

Amino acid modifications

Disulfide bond4 ↔ 60
Disulfide bond18 ↔ 29

Secondary structure

.............................. 185
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P00717 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 22358F632C98342A

FASTA18520,400
        10         20         30         40         50         60 
RTDCYGNVNR IDTTGASCKT AKPEGLSYCG VPASKTIAER DLKAMDRYKT IIKKVGEKLC 

        70         80         90        100        110        120 
VEPAVIAGII SRESHAGKVL KNGWGDRGNG FGLMQVDKRS HKPQGTWNGE VHITQGTTIL 

       130        140        150        160        170        180 
TDFIKRIQKK FPSWTKDQQL KGGISAYNAG AGNVRSYARM DIGTTHDDYA NDVVARAQYY 


KQHGY 

« Hide

References

[1]"Complete amino acid sequence of the goose-type lysozyme from the egg white of the black swan."
Simpson R.J., Begg G.S., Dorow D.S., Morgan F.J.
Biochemistry 19:1814-1819(1980) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Egg white.
[2]"Internal amino acid sequencing of proteins by in situ cyanogen bromide cleavage in polyacrylamide gels."
Jahnen W., Ward L.D., Reid G.E., Moritz R.L., Simpson R.J.
Biochem. Biophys. Res. Commun. 166:139-145(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 46-68 AND 95-111.
[3]"A strategy for rapid and effective refinement applied to black swan lysozyme."
Zao Z., Esnouf R., Isaacs N., Stuart D.
Acta Crystallogr. D 51:331-336(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS).
[4]"Structure of a bulgecin-inhibited g-type lysozyme from the egg white of the Australian black swan. A comparison of the binding of bulgecin to three muramidases."
Karlsen S., Hough E., Rao Z.H., Isaacs N.W.
Acta Crystallogr. D 52:105-114(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.45 ANGSTROMS).

Cross-references

Sequence databases

PIRLZWSG. A00872.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1GBSX-ray1.50A1-185[»]
1LSPX-ray2.45A1-185[»]
ProteinModelPortalP00717.
SMRP00717. Positions 1-185.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH23. Glycoside Hydrolase Family 23.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG006299.

Family and domain databases

InterProIPR002152. Glyco_hydro_23.
IPR023346. Lysozyme-like_dom.
IPR008258. TGlycosylase-like_SLT.
[Graphical view]
PfamPF01464. SLT. 1 hit.
[Graphical view]
PIRSFPIRSF001065. Lysozyme_g. 1 hit.
PRINTSPR00749. LYSOZYMEG.
SUPFAMSSF53955. SSF53955. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP00717.

Entry information

Entry nameLYG_CYGAT
AccessionPrimary (citable) accession number: P00717
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: October 16, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries