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Protein

Lysozyme C

Gene

LYZ

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.PROSITE-ProRule annotation1 Publication

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei531
Active sitei701
Binding sitei119Substrate1

GO - Molecular functioni

  • beta-N-acetylglucosaminidase activity Source: AgBase
  • identical protein binding Source: IntAct
  • lysozyme activity Source: GO_Central

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

Enzyme and pathway databases

BRENDAi3.2.1.17. 1306.
ReactomeiR-GGA-6798695. Neutrophil degranulation.
R-GGA-6803157. Antimicrobial peptides.
SABIO-RKP00698.

Protein family/group databases

CAZyiGH22. Glycoside Hydrolase Family 22.

Names & Taxonomyi

Protein namesi
Recommended name:
Lysozyme C (EC:3.2.1.17)
Alternative name(s):
1,4-beta-N-acetylmuramidase C
Allergen Gal d IV
Allergen: Gal d 4
Gene namesi
Name:LYZ
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  • endoplasmic reticulum Source: AgBase
  • extracellular exosome Source: Ensembl
  • extracellular space Source: AgBase
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3294. Gal d 4.0101.
362. Gal d 4.

Chemistry databases

ChEMBLiCHEMBL1932892.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 181 PublicationAdd BLAST18
ChainiPRO_000001849519 – 147Lysozyme CAdd BLAST129

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi24 ↔ 145
Disulfide bondi48 ↔ 133
Disulfide bondi82 ↔ 98
Disulfide bondi94 ↔ 112

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP00698.
PRIDEiP00698.

PTM databases

iPTMnetiP00698.

Expressioni

Tissue specificityi

In the egg white and polymorphonuclear leukocytes.

Gene expression databases

BgeeiENSGALG00000009963.
ExpressionAtlasiP00698. baseline and differential.

Interactioni

Subunit structurei

Monomer.

Binary interactionsi

WithEntry#Exp.IntActNotes
itself4EBI-1029543,EBI-1029543
degPP0C0V08EBI-1029543,EBI-547165From a different organism.

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

BioGridi676478. 1 interactor.
DIPiDIP-46258N.
IntActiP00698. 4 interactors.
STRINGi9031.ENSGALP00000016177.

Structurei

Secondary structure

1147
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi23 – 32Combined sources10
Turni33 – 37Combined sources5
Helixi38 – 40Combined sources3
Helixi43 – 54Combined sources12
Beta strandi55 – 57Combined sources3
Beta strandi61 – 63Combined sources3
Beta strandi65 – 67Combined sources3
Beta strandi69 – 71Combined sources3
Turni72 – 75Combined sources4
Turni78 – 81Combined sources4
Beta strandi85 – 87Combined sources3
Beta strandi95 – 97Combined sources3
Helixi98 – 102Combined sources5
Beta strandi103 – 105Combined sources3
Helixi107 – 118Combined sources12
Beta strandi119 – 121Combined sources3
Helixi123 – 125Combined sources3
Helixi127 – 132Combined sources6
Turni133 – 135Combined sources3
Helixi138 – 141Combined sources4
Turni142 – 144Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
132LX-ray1.80A19-147[»]
193LX-ray1.33A19-147[»]
194LX-ray1.40A19-147[»]
1A2YX-ray1.50C19-147[»]
1AKIX-ray1.50A19-147[»]
1AT5X-ray1.80A19-147[»]
1AT6X-ray1.80A19-147[»]
1AZFX-ray1.80A19-147[»]
1B0DX-ray1.84A19-147[»]
1B2KX-ray1.60A/B19-147[»]
1BGIX-ray1.70A19-147[»]
1BHZX-ray3.90A19-147[»]
1BVKX-ray2.70C/F19-147[»]
1BVXX-ray1.80A19-147[»]
1BWHX-ray1.80A19-147[»]
1BWIX-ray1.80A19-147[»]
1BWJX-ray1.80A19-147[»]
1C08X-ray2.30C19-147[»]
1C10X-ray2.03A19-147[»]
1DPWX-ray1.64A19-147[»]
1DPXX-ray1.65A19-147[»]
1DQJX-ray2.00C19-147[»]
1E8LNMR-A19-147[»]
1F0WX-ray1.90A19-147[»]
1F10X-ray1.70A19-147[»]
1F3JX-ray3.10P/Q29-42[»]
1FDLX-ray2.50Y19-147[»]
1FLQX-ray1.80A19-147[»]
1FLUX-ray1.78A19-147[»]
1FLWX-ray1.81A19-147[»]
1FLYX-ray1.83A19-147[»]
1FN5X-ray1.78A19-147[»]
1G7HX-ray1.85C19-147[»]
1G7IX-ray1.80C19-147[»]
1G7JX-ray1.75C19-147[»]
1G7LX-ray2.00C19-147[»]
1G7MX-ray1.90C19-147[»]
1GPQX-ray1.60C/D19-147[»]
1GWDX-ray1.77A19-147[»]
1GXVNMR-219-147[»]
1GXXNMR-A19-147[»]
1H6MX-ray1.64A19-147[»]
1H87X-ray1.72A19-147[»]
1HC0X-ray1.82A19-147[»]
1HELX-ray1.70A19-147[»]
1HEMX-ray1.80A19-147[»]
1HENX-ray1.80A19-147[»]
1HEOX-ray1.80A19-147[»]
1HEPX-ray1.80A19-147[»]
1HEQX-ray1.80A19-147[»]
1HERX-ray1.80A19-147[»]
1HEWX-ray1.75A19-147[»]
1HF4X-ray1.45A/B19-147[»]
1HSWX-ray2.00A19-147[»]
1HSXX-ray1.90A19-147[»]
1IC4X-ray2.50Y19-147[»]
1IC5X-ray2.30Y19-147[»]
1IC7X-ray2.10Y19-147[»]
1IEEX-ray0.94A19-147[»]
1IO5neutron diffraction2.00A19-147[»]
1IOQX-ray1.79A19-147[»]
1IORX-ray1.76A19-147[»]
1IOSX-ray1.76A19-147[»]
1IOTX-ray1.75A19-147[»]
1IR7X-ray1.90A19-147[»]
1IR8X-ray1.63A19-147[»]
1IR9X-ray1.90A19-147[»]
1J1OX-ray1.80Y19-147[»]
1J1PX-ray1.80Y19-147[»]
1J1XX-ray1.80Y19-147[»]
1JA2X-ray2.87A19-147[»]
1JA4X-ray2.94A19-147[»]
1JA6X-ray2.96A19-147[»]
1JA7X-ray2.98A19-147[»]
1JISX-ray1.90A19-147[»]
1JITX-ray1.90A19-147[»]
1JIYX-ray1.90A19-147[»]
1JJ0X-ray1.90A19-147[»]
1JJ1X-ray1.90A19-147[»]
1JJ3X-ray1.90A/B19-147[»]
1JPOX-ray2.10A19-147[»]
1JTOX-ray2.50L/M19-147[»]
1JTTX-ray2.10L19-138[»]
1KIPX-ray2.10C19-147[»]
1KIQX-ray1.85C19-147[»]
1KIRX-ray2.00C19-147[»]
1KXWX-ray1.96A19-147[»]
1KXXX-ray1.71A19-147[»]
1KXYX-ray1.79A19-147[»]
1LCNX-ray1.63A/B19-147[»]
1LJ3X-ray2.00A/B19-147[»]
1LJ4X-ray1.95A/B19-147[»]
1LJEX-ray2.00A/B19-147[»]
1LJFX-ray1.80A/B19-147[»]
1LJGX-ray1.90A/B19-147[»]
1LJHX-ray1.80A/B19-147[»]
1LJIX-ray2.00A/B19-147[»]
1LJJX-ray2.00A/B19-147[»]
1LJKX-ray2.10A/B19-147[»]
1LKRX-ray1.60A/B19-147[»]
1LKSX-ray1.10A19-147[»]
1LMAX-ray1.75A19-147[»]
1LPIX-ray2.00A19-147[»]
1LSAX-ray1.70A19-147[»]
1LSBX-ray1.70A19-147[»]
1LSCX-ray1.70A19-147[»]
1LSDX-ray1.70A19-147[»]
1LSEX-ray1.70A19-147[»]
1LSFX-ray1.70A19-147[»]
1LSGX-ray2.40A19-147[»]
1LSMX-ray1.70A19-147[»]
1LSNX-ray1.90A19-147[»]
1LSYX-ray1.90A1-147[»]
1LSZX-ray2.00A1-147[»]
1LYOX-ray1.93A19-147[»]
1LYSX-ray1.72A/B19-147[»]
1LYZX-ray2.00A19-147[»]
1LZ8X-ray1.53A19-147[»]
1LZ9X-ray1.70A19-147[»]
1LZAX-ray1.60A19-147[»]
1LZBX-ray1.50A19-147[»]
1LZCX-ray1.80A19-147[»]
1LZDX-ray1.80A19-147[»]
1LZEX-ray1.80A19-147[»]
1LZGX-ray1.80A19-147[»]
1LZHX-ray6.00A/B19-147[»]
1LZNneutron diffraction1.70A19-147[»]
1LZTX-ray1.97A19-147[»]
1MELX-ray2.50L/M19-147[»]
1MLCX-ray2.50E/F19-147[»]
1N4FX-ray1.78A19-147[»]
1NBYX-ray1.80C19-147[»]
1NBZX-ray1.85C19-147[»]
1NDGX-ray1.90C19-147[»]
1NDMX-ray2.10C19-147[»]
1P2CX-ray2.00C/F19-147[»]
1PS5X-ray2.00A19-147[»]
1QIOX-ray1.20A19-147[»]
1QTKX-ray2.03A19-147[»]
1RCMX-ray1.90A/B19-147[»]
1RFPX-ray1.75A19-147[»]
1RI8X-ray1.85B19-147[»]
1RJCX-ray1.40B19-147[»]
1SF4X-ray2.98A19-147[»]
1SF6X-ray3.22A19-147[»]
1SF7X-ray3.22A19-147[»]
1SFBX-ray3.22A19-147[»]
1SFGX-ray3.22A19-147[»]
1SQ2X-ray1.45L19-147[»]
1T3PX-ray1.60A19-147[»]
1T6VX-ray1.70L/M19-147[»]
1UA6X-ray1.90Y19-147[»]
1UC0X-ray1.85A19-147[»]
1UCOX-ray2.00A/B19-147[»]
1UIAX-ray1.76A19-147[»]
1UIBX-ray1.76A19-147[»]
1UICX-ray1.95A19-147[»]
1UIDX-ray1.95A19-147[»]
1UIEX-ray1.95A19-147[»]
1UIFX-ray1.85A19-147[»]
1UIGX-ray1.95A19-147[»]
1UIHX-ray1.75A19-147[»]
1UUZX-ray1.80C/D19-147[»]
1V7SX-ray1.14A19-147[»]
1V7TX-ray1.13A/B19-147[»]
1VATX-ray1.60A19-147[»]
1VAUX-ray1.50A19-147[»]
1VDPX-ray1.70A/B19-147[»]
1VDQX-ray1.50A19-147[»]
1VDSX-ray1.60A19-147[»]
1VDTX-ray1.70A19-147[»]
1VEDX-ray1.90A19-147[»]
1VFBX-ray1.80C19-147[»]
1W6ZX-ray1.65A19-147[»]
1WTMX-ray1.33A19-147[»]
1WTNX-ray1.13A19-147[»]
1XEIX-ray2.10A19-147[»]
1XEJX-ray2.10A19-147[»]
1XEKX-ray2.30A19-147[»]
1XFPX-ray1.50L19-147[»]
1XGPX-ray2.10C19-147[»]
1XGQX-ray2.10C19-147[»]
1XGRX-ray2.10C19-147[»]
1XGTX-ray2.10C19-147[»]
1XGUX-ray2.10C19-147[»]
1YIKX-ray1.75A19-147[»]
1YILX-ray1.60A19-147[»]
1YKXX-ray1.90X19-147[»]
1YKYX-ray1.90X19-147[»]
1YKZX-ray1.80X19-147[»]
1YL0X-ray1.90X19-147[»]
1YL1X-ray1.90X19-147[»]
1YQVX-ray1.70Y19-147[»]
1Z55X-ray1.90A19-147[»]
1ZMYX-ray3.00L/M19-147[»]
1ZV5X-ray2.00L19-147[»]
1ZVHX-ray1.50L19-147[»]
1ZVYX-ray1.63B19-147[»]
2A6UX-ray-A19-147[»]
2A7DX-ray1.66A19-147[»]
2A7FX-ray1.85A19-147[»]
2AUBX-ray1.70A19-147[»]
2B5ZX-ray1.60A19-147[»]
2BLXX-ray1.40A19-147[»]
2BLYX-ray1.40A19-147[»]
2BPUX-ray1.35A19-147[»]
2C8OX-ray1.50A19-147[»]
2C8PX-ray1.50A19-147[»]
2CDSX-ray2.00A19-147[»]
2CGIX-ray1.35A19-147[»]
2D4IX-ray1.16A/B19-147[»]
2D4JX-ray1.16A19-147[»]
2D4KX-ray1.15A/N19-147[»]
2D6BX-ray1.25A19-147[»]
2D91X-ray2.10A19-147[»]
2DQCX-ray1.80Y19-147[»]
2DQDX-ray1.80Y19-147[»]
2DQEX-ray1.90Y19-147[»]
2DQFX-ray2.50C/F19-147[»]
2DQGX-ray2.30Y19-147[»]
2DQHX-ray2.30Y19-147[»]
2DQIX-ray2.00Y19-147[»]
2DQJX-ray1.80Y19-147[»]
2EIZX-ray1.90C19-147[»]
2EKSX-ray2.00C19-147[»]
2EPEX-ray2.50A19-147[»]
2F2NX-ray1.60A19-147[»]
2F30X-ray1.65A19-147[»]
2F4AX-ray1.95A19-147[»]
2F4GX-ray1.65A19-147[»]
2FBBX-ray1.46A19-147[»]
2G4PX-ray1.84A19-147[»]
2G4QX-ray1.84A19-147[»]
2H9JX-ray1.75A19-147[»]
2H9KX-ray1.75A19-147[»]
2HFMmodel-Y19-147[»]
2HS7X-ray-A19-147[»]
2HS9X-ray-A19-147[»]
2HSOX-ray-A19-147[»]
2HTXX-ray1.56A19-147[»]
2HU1X-ray1.63A19-147[»]
2HU3X-ray1.30A19-147[»]
2HUBX-ray1.20A19-147[»]
2I25X-ray1.80L/M19-147[»]
2I26X-ray2.50L/M/Q19-147[»]
2I6ZX-ray1.90A19-147[»]
2IFFX-ray2.65Y19-147[»]
2LYMX-ray2.00A19-147[»]
2LYOX-ray1.93A19-147[»]
2LYZX-ray2.00A19-147[»]
2LZHX-ray6.00A19-147[»]
2LZTX-ray1.97A19-147[»]
2PC2X-ray1.54A19-147[»]
2Q0MX-ray1.70X19-147[»]
2VB1X-ray0.65A19-147[»]
2W1LX-ray1.51A19-147[»]
2W1MX-ray1.78A19-147[»]
2W1XX-ray1.70A19-147[»]
2W1YX-ray1.73A19-147[»]
2WARX-ray1.80A19-147[»]
2X0AX-ray1.52A19-147[»]
2XBRX-ray1.29A19-147[»]
2XBSX-ray1.37A19-147[»]
2XJWX-ray1.67A19-147[»]
2XTHX-ray1.80A19-147[»]
2YBHX-ray2.00A19-147[»]
2YBIX-ray2.00A19-147[»]
2YBJX-ray2.00A19-147[»]
2YBLX-ray2.00A19-147[»]
2YBMX-ray2.00A19-147[»]
2YBNX-ray2.00A19-147[»]
2YDGX-ray2.00A19-147[»]
2YSSX-ray2.40C19-147[»]
2YVBX-ray1.62A19-147[»]
2Z12X-ray1.15A19-147[»]
2Z18X-ray1.15A19-147[»]
2Z19X-ray1.15A19-147[»]
2ZNWX-ray2.71Y/Z19-147[»]
2ZNXX-ray2.30Y/Z19-147[»]
2ZQ3X-ray1.60A19-147[»]
2ZQ4X-ray2.00A19-147[»]
2ZYPX-ray1.18A19-147[»]
3A34X-ray1.65A19-147[»]
3A3QX-ray2.00A19-147[»]
3A3RX-ray1.90X19-147[»]
3A67X-ray1.80Y19-147[»]
3A6BX-ray1.80Y19-147[»]
3A6CX-ray1.80Y19-147[»]
3A8ZX-ray1.40A19-147[»]
3A90X-ray1.45A19-147[»]
3A91X-ray1.55A19-147[»]
3A92X-ray1.50A19-147[»]
3A93X-ray1.55A19-147[»]
3A94X-ray1.55A19-147[»]
3A95X-ray1.50A19-147[»]
3A96X-ray1.75A19-147[»]
3AGGX-ray1.60G19-147[»]
3AGHX-ray1.49A19-147[»]
3AGIX-ray1.20A19-147[»]
3AJNX-ray1.05A19-147[»]
3ATNX-ray1.17A19-147[»]
3ATOX-ray1.17A19-147[»]
3AW6X-ray2.10A19-147[»]
3AW7X-ray2.10A19-147[»]
3AZ4X-ray1.62A19-147[»]
3AZ5X-ray2.34A19-147[»]
3AZ6X-ray1.50A19-147[»]
3AZ7X-ray2.10A19-147[»]
3B6LX-ray2.30A1-147[»]
3B72X-ray1.50A1-147[»]
3D9AX-ray1.20C19-147[»]
3E3DX-ray1.55A19-147[»]
3EMSX-ray1.65A19-147[»]
3EXDX-ray1.49A19-147[»]
3F6ZX-ray2.50A/C19-147[»]
3G3AX-ray2.20B/D/F/H19-147[»]
3G3BX-ray2.40B/D/F/H19-147[»]
3HFMX-ray3.00Y19-147[»]
3IJUX-ray1.60A19-147[»]
3IJVX-ray1.70A19-147[»]
3J4Gelectron microscopy2.90A19-147[»]
3J6Kelectron microscopy2.50A19-147[»]
3KAMX-ray1.59A19-147[»]
3LYMX-ray2.00A19-147[»]
3LYOX-ray1.93A19-147[»]
3LYTX-ray1.90A/B19-147[»]
3LYZX-ray2.00A19-147[»]
3LZTX-ray0.93A19-147[»]
3M18X-ray1.95B19-147[»]
3M3UX-ray2.35A19-147[»]
3MBEX-ray2.89P/Q29-45[»]
3N9AX-ray1.40A19-147[»]
3N9CX-ray1.50A19-147[»]
3N9EX-ray1.38A19-147[»]
3OJPX-ray1.81A19-147[»]
3OK0X-ray1.82A19-147[»]
3OTPX-ray3.76G/H/I/J/K/L36-76[»]
3P4ZX-ray1.60A19-147[»]
3P64X-ray1.30A19-147[»]
3P65X-ray2.10A19-147[»]
3P66X-ray1.36A19-147[»]
3P68X-ray1.60A19-147[»]
3QE8X-ray1.49A/B19-147[»]
3QNGX-ray1.55A19-147[»]
3QY4X-ray1.65A19-146[»]
3RNXX-ray1.86A19-147[»]
3RT5X-ray1.75X19-147[»]
3RU5X-ray1.35A19-147[»]
3RW8X-ray1.86A19-147[»]
3RZ4X-ray1.80A19-147[»]
3SP3X-ray1.80A19-147[»]
3T6UX-ray2.21A19-147[»]
3TMUX-ray1.90A1-147[»]
3TMVX-ray1.90A1-147[»]
3TMWX-ray1.90A1-147[»]
3TMXX-ray1.90A1-147[»]
3TXBX-ray1.59A19-147[»]
3TXDX-ray1.53A19-147[»]
3TXEX-ray1.70A19-147[»]
3TXFX-ray1.69A19-147[»]
3TXGX-ray1.70A19-147[»]
3TXHX-ray1.69A19-147[»]
3TXIX-ray1.60A19-147[»]
3TXJX-ray2.48A19-147[»]
3TXKX-ray3.00A19-147[»]
3ULRX-ray1.65A19-147[»]
3W6AX-ray1.77A19-147[»]
3WL2X-ray0.96A/B19-147[»]
3WMKX-ray1.46A19-147[»]
3WPJX-ray2.00A19-147[»]
3WPKX-ray2.00A19-147[»]
3WPLX-ray2.00A19-147[»]
3WU7X-ray2.00A19-147[»]
3WU8X-ray2.00A19-147[»]
3WU9X-ray2.00A19-147[»]
3WUAX-ray2.00A19-147[»]
3WULX-ray2.00A19-147[»]
3WUMX-ray2.00A19-147[»]
3WUNX-ray2.40A19-147[»]
3WVXX-ray1.58A19-147[»]
3WVYX-ray1.56A19-147[»]
3WW5X-ray1.53A19-147[»]
3WW6X-ray1.53A19-147[»]
3WXTX-ray2.00A19-147[»]
3WXUX-ray2.00A19-147[»]
3ZEKX-ray1.43A19-147[»]
3ZVQX-ray2.00A19-88[»]
B90-147[»]
4A7DX-ray1.50A19-147[»]
4A8Aelectron microscopy14.20M19-147[»]
4A8Belectron microscopy13.00M/N/O/P/Q/R19-147[»]
4AGAX-ray1.50A19-147[»]
4AXTX-ray1.10A19-147[»]
4B0DX-ray1.10A19-147[»]
4B1AX-ray1.67A19-147[»]
4B49X-ray1.15A19-147[»]
4B4EX-ray1.00A19-147[»]
4B4IX-ray1.20A19-147[»]
4B4JX-ray1.25A19-147[»]
4BADX-ray1.35A19-147[»]
4BAFX-ray1.51A19-147[»]
4BAPX-ray1.21A19-147[»]
4BS7X-ray1.70A19-147[»]
4C3WX-ray1.28A19-147[»]
4CJ2X-ray1.50A/B1-147[»]
4D9ZX-ray1.71A19-147[»]
4DC4X-ray2.65A/B/C19-147[»]
4DD0X-ray1.70A19-147[»]
4DD1X-ray1.70A/B19-147[»]
4DD2X-ray1.55A19-147[»]
4DD3X-ray1.70A19-147[»]
4DD7X-ray1.60A19-147[»]
4DD9X-ray1.60A19-147[»]
4DDAX-ray2.48A19-147[»]
4DDBX-ray3.00A19-147[»]
4DDCX-ray1.80A/B19-147[»]
4DT3X-ray1.80A19-147[»]
4E3UX-ray1.50A19-147[»]
4EOFX-ray1.83A19-147[»]
4ET8X-ray1.90A19-147[»]
4ET9X-ray1.90A19-147[»]
4ETAX-ray1.91A19-147[»]
4ETBX-ray1.91A19-147[»]
4ETCX-ray1.91A19-147[»]
4ETDX-ray1.90A19-147[»]
4ETEX-ray1.90A19-147[»]
4FJRX-ray1.86A19-147[»]
4G49X-ray2.40A19-147[»]
4G4BX-ray2.10A19-147[»]
4G4CX-ray2.00A19-147[»]
4G4HX-ray2.00A19-147[»]
4GCBX-ray1.80A19-147[»]
4GCCX-ray2.00A19-147[»]
4GCDX-ray2.80A19-147[»]
4GCEX-ray2.90A19-147[»]
4GCFX-ray3.50A19-147[»]
4GLAX-ray2.75A/B19-147[»]
4GLVX-ray2.57A/C/E/G19-147[»]
4GN3X-ray1.95A/C/E/G/I/K/M/O/Q19-147[»]
4GN4X-ray1.86A19-147[»]
4GN5X-ray1.86C/D19-147[»]
4H1PX-ray2.30A19-147[»]
4H8XX-ray1.20A19-147[»]
4H8YX-ray1.20A19-147[»]
4H8ZX-ray1.20A19-147[»]
4H90X-ray1.20A19-147[»]
4H91X-ray1.20A19-147[»]
4H92X-ray1.20A19-147[»]
4H93X-ray1.20A19-147[»]
4H94X-ray1.20A19-147[»]
4H9AX-ray1.20A19-147[»]
4H9BX-ray1.20A19-147[»]
4H9CX-ray1.20A19-147[»]
4H9EX-ray1.20A19-147[»]
4H9FX-ray1.20A19-147[»]
4H9HX-ray1.20A19-147[»]
4H9IX-ray1.20A19-147[»]
4HP0X-ray1.19A19-147[»]
4HPIX-ray1.19A19-147[»]
4HSFX-ray1.82A19-147[»]
4HTKX-ray1.20A19-147[»]
4HTNX-ray1.30A19-147[»]
4HTQX-ray1.40A19-147[»]
4HV1X-ray2.30A19-147[»]
4HV2X-ray2.50A19-147[»]
4I8SX-ray2.00A19-147[»]
4IASX-ray2.60A19-147[»]
4IATX-ray2.00A19-147[»]
4II8X-ray1.88A19-147[»]
4J1AX-ray1.79A19-147[»]
4J1BX-ray1.66A19-147[»]
4J7VX-ray1.54A19-147[»]
4KXIX-ray2.00A19-147[»]
4LFPX-ray1.72A19-147[»]
4LFXX-ray2.10A19-147[»]
4LGKX-ray1.96A19-147[»]
4LT0X-ray2.10A19-147[»]
4LT1X-ray2.30A19-147[»]
4LT2X-ray2.00A19-147[»]
4LT3X-ray2.00A19-147[»]
4LYBX-ray1.21A19-147[»]
4LYCX-ray1.35A19-147[»]
4LYMX-ray2.10A19-147[»]
4LYOX-ray2.05A19-147[»]
4LYTX-ray1.90A/B19-147[»]
4LYZX-ray2.00A19-147[»]
4LZTX-ray0.95A19-147[»]
4M4OX-ray2.00A19-147[»]
4M6DX-ray2.68A/C/E/G/I/K19-147[»]
4MR1X-ray1.99A19-147[»]
4N0JX-ray1.90A/B20-147[»]
4N1CX-ray1.70C19-147[»]
4N1EX-ray2.23I/J/K/L19-147[»]
4N5RX-ray2.10A19-147[»]
4N8ZX-ray1.20A19-147[»]
4N9RX-ray1.55A19-147[»]
4NEBX-ray1.48A19-147[»]
4NFVX-ray1.63A19-147[»]
4NG1X-ray1.82A19-147[»]
4NG8X-ray1.09A19-147[»]
4NGIX-ray1.70A19-147[»]
4NGJX-ray1.10A19-147[»]
4NGKX-ray1.50A19-147[»]
4NGLX-ray1.52A19-147[»]
4NGOX-ray1.58A19-147[»]
4NGVX-ray1.64A19-147[»]
4NGWX-ray1.37A19-147[»]
4NGYX-ray1.35A19-147[»]
4NGZX-ray1.70A19-147[»]
4NHIX-ray1.34A19-147[»]
4NHPX-ray1.42A19-147[»]
4NHQX-ray1.92A19-147[»]
4NHSX-ray1.99A19-147[»]
4NHTX-ray1.65A19-147[»]
4NIJX-ray1.86A19-147[»]
4NSGX-ray2.00A19-147[»]
4NSHX-ray2.10A19-147[»]
4NSIX-ray2.30A19-147[»]
4NSJX-ray1.70A19-147[»]
4NWEX-ray1.58A19-147[»]
4NWHX-ray1.65A19-147[»]
4NY5X-ray1.85A19-147[»]
4O34X-ray2.09A19-147[»]
4OOOX-ray2.15A19-147[»]
4OOTX-ray1.80A19-147[»]
4OW9X-ray2.10A/B19-147[»]
4OWAX-ray1.80A/B19-147[»]
4OWBX-ray1.69A19-147[»]
4OWCX-ray1.62A19-147[»]
4OWEX-ray1.41A19-147[»]
4OWHX-ray1.48A19-147[»]
4P2EX-ray1.60A19-147[»]
4PGJX-ray2.60B/D19-147[»]
4PHIX-ray1.81A/B/C/D19-147[»]
4PPOX-ray1.73A19-147[»]
4PRQX-ray1.72A/B/C/D19-147[»]
4PRUX-ray2.20A/B19-147[»]
4QEQX-ray1.38A19-147[»]
4QGZX-ray2.51A19-147[»]
4QY9X-ray2.05A19-147[»]
4R0FX-ray1.94A/B19-147[»]
4R6CX-ray1.70A19-147[»]
4RDSX-ray1.23A19-147[»]
4RLMX-ray1.90A19-147[»]
4RLNX-ray2.17A19-147[»]
4RW1X-ray1.90A19-147[»]
4RW2X-ray2.30A19-147[»]
4TSAX-ray2.27A19-147[»]
4TSBX-ray1.95A19-147[»]
4TSCX-ray1.92A19-147[»]
4TTDX-ray2.15A/B19-147[»]
4TUNX-ray1.92A/B19-147[»]
4TWSX-ray1.45A19-147[»]
4U3XX-ray2.26B/D19-147[»]
4UWNX-ray1.67A19-147[»]
4UWUX-ray1.78A19-147[»]
4UWVX-ray1.77A19-147[»]
4W94X-ray1.55A19-147[»]
4W96X-ray1.50A19-147[»]
4WG1X-ray1.70A1-147[»]
4WG7X-ray1.70A1-147[»]
4WL6X-ray1.85A1-147[»]
4WL7X-ray1.95A1-147[»]
4WLDX-ray1.54A19-147[»]
4WLTX-ray1.60A19-147[»]
4WLXX-ray1.60A19-147[»]
4WLYX-ray1.62A19-147[»]
4WM1X-ray1.60A19-147[»]
4WM2X-ray1.60A19-147[»]
4WM3X-ray1.55A19-147[»]
4WM4X-ray1.60A19-147[»]
4WM5X-ray1.60A19-147[»]
4WM6X-ray1.85A/B/C/D19-147[»]
4WMGX-ray2.50A19-147[»]
4WO6X-ray2.00A19-147[»]
4WO9X-ray1.99A19-147[»]
4WOAX-ray1.80A19-147[»]
4X3BX-ray2.10A19-147[»]
4XADX-ray1.25A19-147[»]
4XENX-ray1.55A19-147[»]
4XJBX-ray1.80A19-147[»]
4XJDX-ray1.80A19-147[»]
4XJFX-ray1.80A19-147[»]
4XJGX-ray1.80A19-147[»]
4XJHX-ray2.00A19-147[»]
4XJIX-ray2.00A19-147[»]
4XN6X-ray1.35A19-147[»]
4XYYX-ray1.38A19-147[»]
4YEMX-ray1.47A19-147[»]
4YENX-ray2.00A19-147[»]
4YEOX-ray0.98A19-146[»]
4YM8X-ray2.10A19-147[»]
4YOPX-ray2.10A19-147[»]
4Z3MX-ray2.15A19-147[»]
4Z41X-ray1.89A19-147[»]
4Z46X-ray1.85A19-147[»]
4Z98X-ray1.55A19-147[»]
4ZEEX-ray1.95A19-147[»]
4ZFPX-ray1.96A19-147[»]
4ZIXX-ray1.89A19-147[»]
5A3Eelectron microscopy2.50A19-147[»]
5A3ZX-ray1.59A/B1-147[»]
5AMYX-ray1.80A19-147[»]
5APCX-ray1.70A19-147[»]
5APDX-ray1.70A19-147[»]
5APEX-ray1.70A19-147[»]
5APFX-ray1.70A19-147[»]
5B05X-ray1.80A19-147[»]
5B06X-ray1.80A19-147[»]
5B07X-ray1.80A19-147[»]
5B59X-ray2.00A19-147[»]
5C6IX-ray1.90A19-147[»]
5C6JX-ray2.10A19-147[»]
5C6LX-ray2.10A19-147[»]
5D5CX-ray1.70A19-147[»]
5D5FX-ray1.50A19-147[»]
5DL9X-ray1.38A19-147[»]
5DLAX-ray1.22A19-147[»]
5DM9X-ray2.30A19-147[»]
5E4PX-ray1.79A19-147[»]
5EBHX-ray1.20A19-147[»]
5F14X-ray1.15A19-147[»]
5F16X-ray1.20A19-147[»]
5F81X-ray2.13A19-147[»]
5F9UX-ray1.85A19-147[»]
5F9XX-ray1.94A19-147[»]
5FCPX-ray1.55A19-147[»]
5FDJX-ray1.80A19-147[»]
5FEKX-ray1.80A19-147[»]
5FELX-ray1.80A19-147[»]
5HLLX-ray1.70A19-147[»]
5HMJX-ray1.30A19-147[»]
5HMVX-ray0.98A19-146[»]
5HNCX-ray1.76A19-147[»]
5HNLX-ray2.42A19-147[»]
5HQ1X-ray1.00A19-146[»]
5I5QX-ray1.42A19-147[»]
5IDDX-ray1.13A19-147[»]
5J7CX-ray2.54A/B19-147[»]
5JENX-ray2.30B/D19-147[»]
5KJ9X-ray1.20A19-147[»]
5KXKX-ray1.20A19-147[»]
5KXLX-ray1.20A19-147[»]
5KXMX-ray1.20A19-147[»]
5KXNX-ray1.20A19-147[»]
5KXOX-ray1.20A19-147[»]
5KXPX-ray1.20A19-147[»]
5KXRX-ray1.20A19-147[»]
5KXSX-ray1.20A19-147[»]
5KXTX-ray1.20A19-147[»]
5KXWX-ray1.20A19-147[»]
5KXXX-ray1.20A19-147[»]
5KXYX-ray1.20A19-147[»]
5KXZX-ray1.20A19-147[»]
5KY1X-ray1.20A19-147[»]
5L3HX-ray1.70A19-147[»]
5L3IX-ray1.70A19-147[»]
5L9JX-ray1.50A19-147[»]
5LINX-ray1.50A19-147[»]
5LIOX-ray1.50A19-147[»]
5LVGX-ray2.00A19-147[»]
5LVHX-ray1.55A19-147[»]
5LVIX-ray1.70A19-147[»]
5LVJX-ray1.60A19-147[»]
5LXWX-ray1.00A19-147[»]
5LYMX-ray1.80A/B19-147[»]
5LYTX-ray1.90A19-147[»]
5LYZX-ray2.00A19-147[»]
6LYTX-ray1.90A19-147[»]
6LYZX-ray2.00A19-147[»]
7LYZX-ray2.50A19-147[»]
8LYZX-ray2.50A19-147[»]
9LYZX-ray2.50A19-147[»]
ProteinModelPortaliP00698.
SMRiP00698.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP00698.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 22 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IXGD. Eukaryota.
ENOG4111QHM. LUCA.
GeneTreeiENSGT00550000074398.
HOGENOMiHOG000037357.
HOVERGENiHBG052297.
InParanoidiP00698.
KOiK13915.
OMAiFGRCELA.
OrthoDBiEOG091G0R9V.
PhylomeDBiP00698.
TreeFamiTF324882.

Family and domain databases

CDDicd00119. LYZ1. 1 hit.
InterProiIPR001916. Glyco_hydro_22.
IPR019799. Glyco_hydro_22_CS.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
[Graphical view]
PfamiPF00062. Lys. 1 hit.
[Graphical view]
PRINTSiPR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTiSM00263. LYZ1. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
PROSITEiPS00128. LACTALBUMIN_LYSOZYME_1. 1 hit.
PS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P00698-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSLLILVLC FLPLAALGKV FGRCELAAAM KRHGLDNYRG YSLGNWVCAA
60 70 80 90 100
KFESNFNTQA TNRNTDGSTD YGILQINSRW WCNDGRTPGS RNLCNIPCSA
110 120 130 140
LLSSDITASV NCAKKIVSDG NGMNAWVAWR NRCKGTDVQA WIRGCRL
Length:147
Mass (Da):16,239
Last modified:July 21, 1986 - v1
Checksum:i81E85743FF579468
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti49A → V in CAA23711 (PubMed:6934509).Curated1
Sequence conflicti121N → D AA sequence (PubMed:14063294).Curated1
Sequence conflicti124N → S in CAA23711 (PubMed:6934509).Curated1
Sequence conflicti132R → S in AAA48944 (PubMed:383714).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J00885 Genomic DNA. Translation: AAA48943.1.
V00428 mRNA. Translation: CAA23711.1.
AF410481 Genomic DNA. Translation: AAL69327.1.
M10640 mRNA. Translation: AAA48944.1.
PIRiA93859. LZCH.
RefSeqiNP_990612.1. NM_205281.1.
UniGeneiGga.713.

Genome annotation databases

EnsembliENSGALT00000016196; ENSGALP00000016177; ENSGALG00000009963.
GeneIDi396218.
KEGGigga:396218.

Cross-referencesi

Web resourcesi

Worthington enzyme manual

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J00885 Genomic DNA. Translation: AAA48943.1.
V00428 mRNA. Translation: CAA23711.1.
AF410481 Genomic DNA. Translation: AAL69327.1.
M10640 mRNA. Translation: AAA48944.1.
PIRiA93859. LZCH.
RefSeqiNP_990612.1. NM_205281.1.
UniGeneiGga.713.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
132LX-ray1.80A19-147[»]
193LX-ray1.33A19-147[»]
194LX-ray1.40A19-147[»]
1A2YX-ray1.50C19-147[»]
1AKIX-ray1.50A19-147[»]
1AT5X-ray1.80A19-147[»]
1AT6X-ray1.80A19-147[»]
1AZFX-ray1.80A19-147[»]
1B0DX-ray1.84A19-147[»]
1B2KX-ray1.60A/B19-147[»]
1BGIX-ray1.70A19-147[»]
1BHZX-ray3.90A19-147[»]
1BVKX-ray2.70C/F19-147[»]
1BVXX-ray1.80A19-147[»]
1BWHX-ray1.80A19-147[»]
1BWIX-ray1.80A19-147[»]
1BWJX-ray1.80A19-147[»]
1C08X-ray2.30C19-147[»]
1C10X-ray2.03A19-147[»]
1DPWX-ray1.64A19-147[»]
1DPXX-ray1.65A19-147[»]
1DQJX-ray2.00C19-147[»]
1E8LNMR-A19-147[»]
1F0WX-ray1.90A19-147[»]
1F10X-ray1.70A19-147[»]
1F3JX-ray3.10P/Q29-42[»]
1FDLX-ray2.50Y19-147[»]
1FLQX-ray1.80A19-147[»]
1FLUX-ray1.78A19-147[»]
1FLWX-ray1.81A19-147[»]
1FLYX-ray1.83A19-147[»]
1FN5X-ray1.78A19-147[»]
1G7HX-ray1.85C19-147[»]
1G7IX-ray1.80C19-147[»]
1G7JX-ray1.75C19-147[»]
1G7LX-ray2.00C19-147[»]
1G7MX-ray1.90C19-147[»]
1GPQX-ray1.60C/D19-147[»]
1GWDX-ray1.77A19-147[»]
1GXVNMR-219-147[»]
1GXXNMR-A19-147[»]
1H6MX-ray1.64A19-147[»]
1H87X-ray1.72A19-147[»]
1HC0X-ray1.82A19-147[»]
1HELX-ray1.70A19-147[»]
1HEMX-ray1.80A19-147[»]
1HENX-ray1.80A19-147[»]
1HEOX-ray1.80A19-147[»]
1HEPX-ray1.80A19-147[»]
1HEQX-ray1.80A19-147[»]
1HERX-ray1.80A19-147[»]
1HEWX-ray1.75A19-147[»]
1HF4X-ray1.45A/B19-147[»]
1HSWX-ray2.00A19-147[»]
1HSXX-ray1.90A19-147[»]
1IC4X-ray2.50Y19-147[»]
1IC5X-ray2.30Y19-147[»]
1IC7X-ray2.10Y19-147[»]
1IEEX-ray0.94A19-147[»]
1IO5neutron diffraction2.00A19-147[»]
1IOQX-ray1.79A19-147[»]
1IORX-ray1.76A19-147[»]
1IOSX-ray1.76A19-147[»]
1IOTX-ray1.75A19-147[»]
1IR7X-ray1.90A19-147[»]
1IR8X-ray1.63A19-147[»]
1IR9X-ray1.90A19-147[»]
1J1OX-ray1.80Y19-147[»]
1J1PX-ray1.80Y19-147[»]
1J1XX-ray1.80Y19-147[»]
1JA2X-ray2.87A19-147[»]
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3ZVQX-ray2.00A19-88[»]
B90-147[»]
4A7DX-ray1.50A19-147[»]
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4NIJX-ray1.86A19-147[»]
4NSGX-ray2.00A19-147[»]
4NSHX-ray2.10A19-147[»]
4NSIX-ray2.30A19-147[»]
4NSJX-ray1.70A19-147[»]
4NWEX-ray1.58A19-147[»]
4NWHX-ray1.65A19-147[»]
4NY5X-ray1.85A19-147[»]
4O34X-ray2.09A19-147[»]
4OOOX-ray2.15A19-147[»]
4OOTX-ray1.80A19-147[»]
4OW9X-ray2.10A/B19-147[»]
4OWAX-ray1.80A/B19-147[»]
4OWBX-ray1.69A19-147[»]
4OWCX-ray1.62A19-147[»]
4OWEX-ray1.41A19-147[»]
4OWHX-ray1.48A19-147[»]
4P2EX-ray1.60A19-147[»]
4PGJX-ray2.60B/D19-147[»]
4PHIX-ray1.81A/B/C/D19-147[»]
4PPOX-ray1.73A19-147[»]
4PRQX-ray1.72A/B/C/D19-147[»]
4PRUX-ray2.20A/B19-147[»]
4QEQX-ray1.38A19-147[»]
4QGZX-ray2.51A19-147[»]
4QY9X-ray2.05A19-147[»]
4R0FX-ray1.94A/B19-147[»]
4R6CX-ray1.70A19-147[»]
4RDSX-ray1.23A19-147[»]
4RLMX-ray1.90A19-147[»]
4RLNX-ray2.17A19-147[»]
4RW1X-ray1.90A19-147[»]
4RW2X-ray2.30A19-147[»]
4TSAX-ray2.27A19-147[»]
4TSBX-ray1.95A19-147[»]
4TSCX-ray1.92A19-147[»]
4TTDX-ray2.15A/B19-147[»]
4TUNX-ray1.92A/B19-147[»]
4TWSX-ray1.45A19-147[»]
4U3XX-ray2.26B/D19-147[»]
4UWNX-ray1.67A19-147[»]
4UWUX-ray1.78A19-147[»]
4UWVX-ray1.77A19-147[»]
4W94X-ray1.55A19-147[»]
4W96X-ray1.50A19-147[»]
4WG1X-ray1.70A1-147[»]
4WG7X-ray1.70A1-147[»]
4WL6X-ray1.85A1-147[»]
4WL7X-ray1.95A1-147[»]
4WLDX-ray1.54A19-147[»]
4WLTX-ray1.60A19-147[»]
4WLXX-ray1.60A19-147[»]
4WLYX-ray1.62A19-147[»]
4WM1X-ray1.60A19-147[»]
4WM2X-ray1.60A19-147[»]
4WM3X-ray1.55A19-147[»]
4WM4X-ray1.60A19-147[»]
4WM5X-ray1.60A19-147[»]
4WM6X-ray1.85A/B/C/D19-147[»]
4WMGX-ray2.50A19-147[»]
4WO6X-ray2.00A19-147[»]
4WO9X-ray1.99A19-147[»]
4WOAX-ray1.80A19-147[»]
4X3BX-ray2.10A19-147[»]
4XADX-ray1.25A19-147[»]
4XENX-ray1.55A19-147[»]
4XJBX-ray1.80A19-147[»]
4XJDX-ray1.80A19-147[»]
4XJFX-ray1.80A19-147[»]
4XJGX-ray1.80A19-147[»]
4XJHX-ray2.00A19-147[»]
4XJIX-ray2.00A19-147[»]
4XN6X-ray1.35A19-147[»]
4XYYX-ray1.38A19-147[»]
4YEMX-ray1.47A19-147[»]
4YENX-ray2.00A19-147[»]
4YEOX-ray0.98A19-146[»]
4YM8X-ray2.10A19-147[»]
4YOPX-ray2.10A19-147[»]
4Z3MX-ray2.15A19-147[»]
4Z41X-ray1.89A19-147[»]
4Z46X-ray1.85A19-147[»]
4Z98X-ray1.55A19-147[»]
4ZEEX-ray1.95A19-147[»]
4ZFPX-ray1.96A19-147[»]
4ZIXX-ray1.89A19-147[»]
5A3Eelectron microscopy2.50A19-147[»]
5A3ZX-ray1.59A/B1-147[»]
5AMYX-ray1.80A19-147[»]
5APCX-ray1.70A19-147[»]
5APDX-ray1.70A19-147[»]
5APEX-ray1.70A19-147[»]
5APFX-ray1.70A19-147[»]
5B05X-ray1.80A19-147[»]
5B06X-ray1.80A19-147[»]
5B07X-ray1.80A19-147[»]
5B59X-ray2.00A19-147[»]
5C6IX-ray1.90A19-147[»]
5C6JX-ray2.10A19-147[»]
5C6LX-ray2.10A19-147[»]
5D5CX-ray1.70A19-147[»]
5D5FX-ray1.50A19-147[»]
5DL9X-ray1.38A19-147[»]
5DLAX-ray1.22A19-147[»]
5DM9X-ray2.30A19-147[»]
5E4PX-ray1.79A19-147[»]
5EBHX-ray1.20A19-147[»]
5F14X-ray1.15A19-147[»]
5F16X-ray1.20A19-147[»]
5F81X-ray2.13A19-147[»]
5F9UX-ray1.85A19-147[»]
5F9XX-ray1.94A19-147[»]
5FCPX-ray1.55A19-147[»]
5FDJX-ray1.80A19-147[»]
5FEKX-ray1.80A19-147[»]
5FELX-ray1.80A19-147[»]
5HLLX-ray1.70A19-147[»]
5HMJX-ray1.30A19-147[»]
5HMVX-ray0.98A19-146[»]
5HNCX-ray1.76A19-147[»]
5HNLX-ray2.42A19-147[»]
5HQ1X-ray1.00A19-146[»]
5I5QX-ray1.42A19-147[»]
5IDDX-ray1.13A19-147[»]
5J7CX-ray2.54A/B19-147[»]
5JENX-ray2.30B/D19-147[»]
5KJ9X-ray1.20A19-147[»]
5KXKX-ray1.20A19-147[»]
5KXLX-ray1.20A19-147[»]
5KXMX-ray1.20A19-147[»]
5KXNX-ray1.20A19-147[»]
5KXOX-ray1.20A19-147[»]
5KXPX-ray1.20A19-147[»]
5KXRX-ray1.20A19-147[»]
5KXSX-ray1.20A19-147[»]
5KXTX-ray1.20A19-147[»]
5KXWX-ray1.20A19-147[»]
5KXXX-ray1.20A19-147[»]
5KXYX-ray1.20A19-147[»]
5KXZX-ray1.20A19-147[»]
5KY1X-ray1.20A19-147[»]
5L3HX-ray1.70A19-147[»]
5L3IX-ray1.70A19-147[»]
5L9JX-ray1.50A19-147[»]
5LINX-ray1.50A19-147[»]
5LIOX-ray1.50A19-147[»]
5LVGX-ray2.00A19-147[»]
5LVHX-ray1.55A19-147[»]
5LVIX-ray1.70A19-147[»]
5LVJX-ray1.60A19-147[»]
5LXWX-ray1.00A19-147[»]
5LYMX-ray1.80A/B19-147[»]
5LYTX-ray1.90A19-147[»]
5LYZX-ray2.00A19-147[»]
6LYTX-ray1.90A19-147[»]
6LYZX-ray2.00A19-147[»]
7LYZX-ray2.50A19-147[»]
8LYZX-ray2.50A19-147[»]
9LYZX-ray2.50A19-147[»]
ProteinModelPortaliP00698.
SMRiP00698.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi676478. 1 interactor.
DIPiDIP-46258N.
IntActiP00698. 4 interactors.
STRINGi9031.ENSGALP00000016177.

Chemistry databases

ChEMBLiCHEMBL1932892.

Protein family/group databases

Allergomei3294. Gal d 4.0101.
362. Gal d 4.
CAZyiGH22. Glycoside Hydrolase Family 22.

PTM databases

iPTMnetiP00698.

Proteomic databases

PaxDbiP00698.
PRIDEiP00698.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000016196; ENSGALP00000016177; ENSGALG00000009963.
GeneIDi396218.
KEGGigga:396218.

Organism-specific databases

CTDi4069.

Phylogenomic databases

eggNOGiENOG410IXGD. Eukaryota.
ENOG4111QHM. LUCA.
GeneTreeiENSGT00550000074398.
HOGENOMiHOG000037357.
HOVERGENiHBG052297.
InParanoidiP00698.
KOiK13915.
OMAiFGRCELA.
OrthoDBiEOG091G0R9V.
PhylomeDBiP00698.
TreeFamiTF324882.

Enzyme and pathway databases

BRENDAi3.2.1.17. 1306.
ReactomeiR-GGA-6798695. Neutrophil degranulation.
R-GGA-6803157. Antimicrobial peptides.
SABIO-RKP00698.

Miscellaneous databases

EvolutionaryTraceiP00698.
PROiP00698.

Gene expression databases

BgeeiENSGALG00000009963.
ExpressionAtlasiP00698. baseline and differential.

Family and domain databases

CDDicd00119. LYZ1. 1 hit.
InterProiIPR001916. Glyco_hydro_22.
IPR019799. Glyco_hydro_22_CS.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
[Graphical view]
PfamiPF00062. Lys. 1 hit.
[Graphical view]
PRINTSiPR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTiSM00263. LYZ1. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
PROSITEiPS00128. LACTALBUMIN_LYSOZYME_1. 1 hit.
PS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLYSC_CHICK
AccessioniPrimary (citable) accession number: P00698
Secondary accession number(s): Q90884
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 30, 2016
This is version 187 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

Lysozyme C is capable of both hydrolysis and transglycosylation; it shows also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.