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P00698

- LYSC_CHICK

UniProt

P00698 - LYSC_CHICK

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Protein
Lysozyme C
Gene
LYZ
Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.1 Publication

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei53 – 531
Active sitei70 – 701
Binding sitei119 – 1191Substrate

GO - Molecular functioni

  1. identical protein binding Source: IntAct
  2. lysozyme activity Source: UniProtKB-EC
  3. protein binding Source: IntAct
Complete GO annotation...

GO - Biological processi

  1. cell wall macromolecule catabolic process Source: InterPro
  2. cytolysis Source: UniProtKB-KW
  3. defense response to bacterium Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

Enzyme and pathway databases

ReactomeiREACT_197049. Amyloids.
SABIO-RKP00698.

Protein family/group databases

CAZyiGH22. Glycoside Hydrolase Family 22.

Names & Taxonomyi

Protein namesi
Recommended name:
Lysozyme C (EC:3.2.1.17)
Alternative name(s):
1,4-beta-N-acetylmuramidase C
Allergen Gal d IV
Allergen: Gal d 4
Gene namesi
Name:LYZ
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: AgBase
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3294. Gal d 4.0101.
362. Gal d 4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 18181 Publication
Add
BLAST
Chaini19 – 147129Lysozyme C
PRO_0000018495Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi24 ↔ 1452 Publications
Disulfide bondi48 ↔ 1332 Publications
Disulfide bondi82 ↔ 982 Publications
Disulfide bondi94 ↔ 1122 Publications

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP00698.
PRIDEiP00698.

Expressioni

Tissue specificityi

In the egg white and polymorphonuclear leukocytes.

Interactioni

Subunit structurei

Monomer.

Binary interactionsi

WithEntry#Exp.IntActNotes
itself4EBI-1029543,EBI-1029543
degPP0C0V08EBI-1029543,EBI-547165From a different organism.

Protein-protein interaction databases

BioGridi676478. 2 interactions.
IntActiP00698. 4 interactions.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi23 – 3210
Turni33 – 375
Helixi38 – 403
Helixi43 – 5412
Beta strandi55 – 573
Beta strandi61 – 633
Beta strandi65 – 673
Beta strandi69 – 713
Turni72 – 754
Turni78 – 814
Beta strandi85 – 873
Helixi98 – 1025
Beta strandi103 – 1053
Helixi107 – 11812
Beta strandi119 – 1213
Helixi123 – 1253
Helixi127 – 1326
Turni133 – 1353
Helixi138 – 1414
Turni142 – 1443

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
132LX-ray1.80A19-147[»]
193LX-ray1.33A19-147[»]
194LX-ray1.40A19-147[»]
1A2YX-ray1.50C19-147[»]
1AKIX-ray1.50A19-147[»]
1AT5X-ray1.80A19-147[»]
1AT6X-ray1.80A19-147[»]
1AZFX-ray1.80A19-147[»]
1B0DX-ray1.84A19-147[»]
1B2KX-ray1.60A/B19-147[»]
1BGIX-ray1.70A19-147[»]
1BHZX-ray3.90A19-147[»]
1BVKX-ray2.70C/F19-147[»]
1BVXX-ray1.80A19-147[»]
1BWHX-ray1.80A19-147[»]
1BWIX-ray1.80A19-147[»]
1BWJX-ray1.80A19-147[»]
1C08X-ray2.30C19-147[»]
1C10X-ray2.03A19-147[»]
1DPWX-ray1.64A19-147[»]
1DPXX-ray1.65A19-147[»]
1DQJX-ray2.00C19-147[»]
1E8LNMR-A19-147[»]
1F0WX-ray1.90A19-147[»]
1F10X-ray1.70A19-147[»]
1F3JX-ray3.10P/Q29-42[»]
1FDLX-ray2.50Y19-147[»]
1FLQX-ray1.80A19-147[»]
1FLUX-ray1.78A19-147[»]
1FLWX-ray1.81A19-147[»]
1FLYX-ray1.83A19-147[»]
1FN5X-ray1.78A19-147[»]
1G7HX-ray1.85C19-147[»]
1G7IX-ray1.80C19-147[»]
1G7JX-ray1.75C19-147[»]
1G7LX-ray2.00C19-147[»]
1G7MX-ray1.90C19-147[»]
1GPQX-ray1.60C/D19-147[»]
1GWDX-ray1.77A19-147[»]
1GXVNMR-219-147[»]
1GXXNMR-A19-147[»]
1H6MX-ray1.64A19-147[»]
1H87X-ray1.72A19-147[»]
1HC0X-ray1.82A19-147[»]
1HELX-ray1.70A19-147[»]
1HEMX-ray1.80A19-147[»]
1HENX-ray1.80A19-147[»]
1HEOX-ray1.80A19-147[»]
1HEPX-ray1.80A19-147[»]
1HEQX-ray1.80A19-147[»]
1HERX-ray1.80A19-147[»]
1HEWX-ray1.75A19-147[»]
1HF4X-ray1.45A/B19-147[»]
1HSWX-ray2.00A19-147[»]
1HSXX-ray1.90A19-147[»]
1IC4X-ray2.50Y19-147[»]
1IC5X-ray2.30Y19-147[»]
1IC7X-ray2.10Y19-147[»]
1IEEX-ray0.94A19-147[»]
1IO5neutron diffraction2.00A19-147[»]
1IOQX-ray1.79A19-147[»]
1IORX-ray1.76A19-147[»]
1IOSX-ray1.76A19-147[»]
1IOTX-ray1.75A19-147[»]
1IR7X-ray1.90A19-147[»]
1IR8X-ray1.63A19-147[»]
1IR9X-ray1.90A19-147[»]
1J1OX-ray1.80Y19-147[»]
1J1PX-ray1.80Y19-147[»]
1J1XX-ray1.80Y19-147[»]
1JA2X-ray2.87A19-147[»]
1JA4X-ray2.94A19-147[»]
1JA6X-ray2.96A19-147[»]
1JA7X-ray2.98A19-147[»]
1JISX-ray1.90A19-147[»]
1JITX-ray1.90A19-147[»]
1JIYX-ray1.90A19-147[»]
1JJ0X-ray1.90A19-147[»]
1JJ1X-ray1.90A19-147[»]
1JJ3X-ray1.90A/B19-147[»]
1JPOX-ray2.10A19-147[»]
1JTOX-ray2.50L/M19-147[»]
1JTTX-ray2.10L19-138[»]
1KIPX-ray2.10C19-147[»]
1KIQX-ray1.85C19-147[»]
1KIRX-ray2.00C19-147[»]
1KXWX-ray1.96A19-147[»]
1KXXX-ray1.71A19-147[»]
1KXYX-ray1.79A19-147[»]
1LCNX-ray1.63A/B19-147[»]
1LJ3X-ray2.00A/B19-147[»]
1LJ4X-ray1.95A/B19-147[»]
1LJEX-ray2.00A/B19-147[»]
1LJFX-ray1.80A/B19-147[»]
1LJGX-ray1.90A/B19-147[»]
1LJHX-ray1.80A/B19-147[»]
1LJIX-ray2.00A/B19-147[»]
1LJJX-ray2.00A/B19-147[»]
1LJKX-ray2.10A/B19-147[»]
1LKRX-ray1.60A/B19-147[»]
1LKSX-ray1.10A19-147[»]
1LMAX-ray1.75A19-147[»]
1LPIX-ray2.00A19-147[»]
1LSAX-ray1.70A19-147[»]
1LSBX-ray1.70A19-147[»]
1LSCX-ray1.70A19-147[»]
1LSDX-ray1.70A19-147[»]
1LSEX-ray1.70A19-147[»]
1LSFX-ray1.70A19-147[»]
1LSGX-ray2.40A19-147[»]
1LSMX-ray1.70A19-147[»]
1LSNX-ray1.90A19-147[»]
1LSYX-ray1.90A1-147[»]
1LSZX-ray2.00A1-147[»]
1LYOX-ray1.93A19-147[»]
1LYSX-ray1.72A/B19-147[»]
1LYZX-ray2.00A19-147[»]
1LZ8X-ray1.53A19-147[»]
1LZ9X-ray1.70A19-147[»]
1LZAX-ray1.60A19-147[»]
1LZBX-ray1.50A19-147[»]
1LZCX-ray1.80A19-147[»]
1LZDX-ray1.80A19-147[»]
1LZEX-ray1.80A19-147[»]
1LZGX-ray1.80A19-147[»]
1LZHX-ray6.00A/B19-147[»]
1LZNneutron diffraction1.70A19-147[»]
1LZTX-ray1.97A19-147[»]
1MELX-ray2.50L/M19-147[»]
1MLCX-ray2.50E/F19-147[»]
1N4FX-ray1.78A19-147[»]
1NBYX-ray1.80C19-147[»]
1NBZX-ray1.85C19-147[»]
1NDGX-ray1.90C19-147[»]
1NDMX-ray2.10C19-147[»]
1P2CX-ray2.00C/F19-147[»]
1PS5X-ray2.00A19-147[»]
1QIOX-ray1.20A19-147[»]
1QTKX-ray2.03A19-147[»]
1RCMX-ray1.90A/B19-147[»]
1RFPX-ray1.75A19-147[»]
1RI8X-ray1.85B19-147[»]
1RJCX-ray1.40B19-147[»]
1SF4X-ray2.98A19-147[»]
1SF6X-ray3.22A19-147[»]
1SF7X-ray3.22A19-147[»]
1SFBX-ray3.22A19-147[»]
1SFGX-ray3.22A19-147[»]
1SQ2X-ray1.45L19-147[»]
1T3PX-ray1.60A19-147[»]
1T6VX-ray1.70L/M19-147[»]
1UA6X-ray1.90Y19-147[»]
1UC0X-ray1.85A19-147[»]
1UCOX-ray2.00A/B19-147[»]
1UIAX-ray1.76A19-147[»]
1UIBX-ray1.76A19-147[»]
1UICX-ray1.95A19-147[»]
1UIDX-ray1.95A19-147[»]
1UIEX-ray1.95A19-147[»]
1UIFX-ray1.85A19-147[»]
1UIGX-ray1.95A19-147[»]
1UIHX-ray1.75A19-147[»]
1UUZX-ray1.80C/D19-147[»]
1V7SX-ray1.14A19-147[»]
1V7TX-ray1.13A/B19-147[»]
1VATX-ray1.60A19-147[»]
1VAUX-ray1.50A19-147[»]
1VDPX-ray1.70A/B19-147[»]
1VDQX-ray1.50A19-147[»]
1VDSX-ray1.60A19-147[»]
1VDTX-ray1.70A19-147[»]
1VEDX-ray1.90A19-147[»]
1VFBX-ray1.80C19-147[»]
1W6ZX-ray1.65A19-147[»]
1WTMX-ray1.33A19-147[»]
1WTNX-ray1.13A19-147[»]
1XEIX-ray2.10A19-147[»]
1XEJX-ray2.10A19-147[»]
1XEKX-ray2.30A19-147[»]
1XFPX-ray1.50L19-147[»]
1XGPX-ray2.10C19-147[»]
1XGQX-ray2.10C19-147[»]
1XGRX-ray2.10C19-147[»]
1XGTX-ray2.10C19-147[»]
1XGUX-ray2.10C19-147[»]
1YIKX-ray1.75A19-147[»]
1YILX-ray1.60A19-147[»]
1YKXX-ray1.90X19-147[»]
1YKYX-ray1.90X19-147[»]
1YKZX-ray1.80X19-147[»]
1YL0X-ray1.90X19-147[»]
1YL1X-ray1.90X19-147[»]
1YQVX-ray1.70Y19-147[»]
1Z55X-ray1.90A19-147[»]
1ZMYX-ray3.00L/M19-147[»]
1ZV5X-ray2.00L19-147[»]
1ZVHX-ray1.50L19-147[»]
1ZVYX-ray1.63B19-147[»]
2A6UX-ray-A19-147[»]
2A7DX-ray1.66A19-147[»]
2A7FX-ray1.85A19-147[»]
2AUBX-ray1.70A19-147[»]
2B5ZX-ray1.60A19-147[»]
2BLXX-ray1.40A19-147[»]
2BLYX-ray1.40A19-147[»]
2BPUX-ray1.35A19-147[»]
2C8OX-ray1.50A19-147[»]
2C8PX-ray1.50A19-147[»]
2CDSX-ray2.00A19-147[»]
2CGIX-ray1.35A19-147[»]
2D4IX-ray1.16A/B19-147[»]
2D4JX-ray1.16A19-147[»]
2D4KX-ray1.15A/N19-147[»]
2D6BX-ray1.25A19-147[»]
2D91X-ray2.10A19-147[»]
2DQCX-ray1.80Y19-147[»]
2DQDX-ray1.80Y19-147[»]
2DQEX-ray1.90Y19-147[»]
2DQFX-ray2.50C/F19-147[»]
2DQGX-ray2.30Y19-147[»]
2DQHX-ray2.30Y19-147[»]
2DQIX-ray2.00Y19-147[»]
2DQJX-ray1.80Y19-147[»]
2EIZX-ray1.90C19-147[»]
2EKSX-ray2.00C19-147[»]
2EPEX-ray2.50A19-147[»]
2F2NX-ray1.60A19-147[»]
2F30X-ray1.65A19-147[»]
2F4AX-ray1.95A19-147[»]
2F4GX-ray1.65A19-147[»]
2FBBX-ray1.46A19-147[»]
2G4PX-ray1.84A19-147[»]
2G4QX-ray1.84A19-147[»]
2H9JX-ray1.75A19-147[»]
2H9KX-ray1.75A19-147[»]
2HFMmodel-Y19-147[»]
2HS7X-ray-A19-147[»]
2HS9X-ray-A19-147[»]
2HSOX-ray-A19-147[»]
2HTXX-ray1.56A19-147[»]
2HU1X-ray1.63A19-147[»]
2HU3X-ray1.30A19-147[»]
2HUBX-ray1.20A19-147[»]
2I25X-ray1.80L/M19-147[»]
2I26X-ray2.50L/M/Q19-147[»]
2I6ZX-ray1.90A19-147[»]
2IFFX-ray2.65Y19-147[»]
2LYMX-ray2.00A19-147[»]
2LYOX-ray1.93A19-147[»]
2LYZX-ray2.00A19-147[»]
2LZHX-ray6.00A19-147[»]
2LZTX-ray1.97A19-147[»]
2PC2X-ray1.54A19-147[»]
2Q0MX-ray1.70X19-147[»]
2VB1X-ray0.65A19-147[»]
2W1LX-ray1.51A19-147[»]
2W1MX-ray1.78A19-147[»]
2W1XX-ray1.70A19-147[»]
2W1YX-ray1.73A19-147[»]
2WARX-ray1.80A19-147[»]
2X0AX-ray1.52A19-147[»]
2XBRX-ray1.29A19-147[»]
2XBSX-ray1.37A19-147[»]
2XJWX-ray1.67A19-147[»]
2XTHX-ray1.80A19-147[»]
2YBHX-ray2.00A19-147[»]
2YBIX-ray2.00A19-147[»]
2YBJX-ray2.00A19-147[»]
2YBLX-ray2.00A19-147[»]
2YBMX-ray2.00A19-147[»]
2YBNX-ray2.00A19-147[»]
2YDGX-ray2.00A19-147[»]
2YSSX-ray2.40C19-147[»]
2YVBX-ray1.62A19-147[»]
2Z12X-ray1.15A19-147[»]
2Z18X-ray1.15A19-147[»]
2Z19X-ray1.15A19-147[»]
2ZNWX-ray2.71Y/Z19-147[»]
2ZNXX-ray2.30Y/Z19-147[»]
2ZQ3X-ray1.60A19-147[»]
2ZQ4X-ray2.00A19-147[»]
2ZYPX-ray1.18A19-147[»]
3A34X-ray1.65A19-147[»]
3A3QX-ray2.00A19-147[»]
3A3RX-ray1.90X19-147[»]
3A67X-ray1.80Y19-147[»]
3A6BX-ray1.80Y19-147[»]
3A6CX-ray1.80Y19-147[»]
3A8ZX-ray1.40A19-147[»]
3A90X-ray1.45A19-147[»]
3A91X-ray1.55A19-147[»]
3A92X-ray1.50A19-147[»]
3A93X-ray1.55A19-147[»]
3A94X-ray1.55A19-147[»]
3A95X-ray1.50A19-147[»]
3A96X-ray1.75A19-147[»]
3AGGX-ray1.60G19-147[»]
3AGHX-ray1.49A19-147[»]
3AGIX-ray1.20A19-147[»]
3AJNX-ray1.05A19-147[»]
3ATNX-ray1.17A19-147[»]
3ATOX-ray1.17A19-147[»]
3AW6X-ray2.10A19-147[»]
3AW7X-ray2.10A19-147[»]
3AZ4X-ray1.62A19-147[»]
3AZ5X-ray2.34A19-147[»]
3AZ6X-ray1.50A19-147[»]
3AZ7X-ray2.10A19-147[»]
3B6LX-ray2.30A1-147[»]
3B72X-ray1.50A1-147[»]
3D9AX-ray1.20C19-147[»]
3E3DX-ray1.55A19-147[»]
3EMSX-ray1.65A19-147[»]
3EXDX-ray1.49A19-147[»]
3F6ZX-ray2.50A/C19-147[»]
3G3AX-ray2.20B/D/F/H19-147[»]
3G3BX-ray2.40B/D/F/H19-147[»]
3HFMX-ray3.00Y19-147[»]
3IJUX-ray1.60A19-147[»]
3IJVX-ray1.70A19-147[»]
3J4Gelectron microscopy2.90A19-147[»]
3KAMX-ray1.59A19-147[»]
3LYMX-ray2.00A19-147[»]
3LYOX-ray1.93A19-147[»]
3LYTX-ray1.90A/B19-147[»]
3LYZX-ray2.00A19-147[»]
3LZTX-ray0.93A19-147[»]
3M18X-ray1.95B19-147[»]
3M3UX-ray2.35A19-147[»]
3MBEX-ray2.89P/Q29-45[»]
3N9AX-ray1.40A19-147[»]
3N9CX-ray1.50A19-147[»]
3N9EX-ray1.38A19-147[»]
3OJPX-ray1.81A19-147[»]
3OK0X-ray1.82A19-147[»]
3OTPX-ray3.76G/H/I/J/K/L36-76[»]
3P4ZX-ray1.60A19-147[»]
3P64X-ray1.30A19-147[»]
3P65X-ray2.10A19-147[»]
3P66X-ray1.36A19-147[»]
3P68X-ray1.60A19-147[»]
3QE8X-ray1.49A/B19-147[»]
3QNGX-ray1.55A19-147[»]
3QY4X-ray1.65A19-146[»]
3RNXX-ray1.86A19-147[»]
3RT5X-ray1.75X19-147[»]
3RU5X-ray1.35A19-147[»]
3RW8X-ray1.86A19-147[»]
3RZ4X-ray1.80A19-147[»]
3SP3X-ray1.80A19-147[»]
3T6UX-ray2.21A19-147[»]
3TMUX-ray1.90A1-147[»]
3TMVX-ray1.90A1-147[»]
3TMWX-ray1.90A1-147[»]
3TMXX-ray1.90A1-147[»]
3TXBX-ray1.59A19-147[»]
3TXDX-ray1.53A19-147[»]
3TXEX-ray1.70A19-147[»]
3TXFX-ray1.69A19-147[»]
3TXGX-ray1.70A19-147[»]
3TXHX-ray1.69A19-147[»]
3TXIX-ray1.60A19-147[»]
3TXJX-ray2.48A19-147[»]
3TXKX-ray3.00A19-147[»]
3ULRX-ray1.65A19-147[»]
3VFXX-ray1.95A/B19-147[»]
3W6AX-ray1.77A19-147[»]
3ZEKX-ray1.43A19-147[»]
3ZVQX-ray2.00A19-88[»]
B90-147[»]
4A7DX-ray1.50A19-147[»]
4A8Aelectron microscopy14.20M19-147[»]
4A8Belectron microscopy13.00M/N/O/P/Q/R19-147[»]
4AGAX-ray1.50A19-147[»]
4AXTX-ray1.10A19-147[»]
4B0DX-ray1.10A19-147[»]
4B1AX-ray1.67A19-147[»]
4B49X-ray1.15A19-147[»]
4B4EX-ray1.00A19-147[»]
4B4IX-ray1.20A19-147[»]
4B4JX-ray1.25A19-147[»]
4BADX-ray1.35A19-147[»]
4BAFX-ray1.51A19-147[»]
4BAPX-ray1.21A19-147[»]
4BS7X-ray1.70A19-147[»]
4CJ2X-ray1.50A/B1-147[»]
4D9ZX-ray1.71A19-147[»]
4DC4X-ray2.65A/B/C19-147[»]
4DD0X-ray1.70A19-147[»]
4DD1X-ray1.70A/B19-147[»]
4DD2X-ray1.55A19-147[»]
4DD3X-ray1.70A19-147[»]
4DD4X-ray1.70A19-147[»]
4DD6X-ray1.70A19-147[»]
4DD7X-ray1.60A19-147[»]
4DD9X-ray1.60A19-147[»]
4DDAX-ray2.48A19-147[»]
4DDBX-ray3.00A19-147[»]
4DDCX-ray1.80A/B19-147[»]
4DT3X-ray1.80A19-147[»]
4E3UX-ray1.50A19-147[»]
4EOFX-ray1.83A19-147[»]
4ET8X-ray1.90A19-147[»]
4ET9X-ray1.90A19-147[»]
4ETAX-ray1.91A19-147[»]
4ETBX-ray1.91A19-147[»]
4ETCX-ray1.91A19-147[»]
4ETDX-ray1.90A19-147[»]
4ETEX-ray1.90A19-147[»]
4FJRX-ray1.86A19-147[»]
4G49X-ray2.40A19-147[»]
4G4AX-ray2.40A19-147[»]
4G4BX-ray2.10A19-147[»]
4G4CX-ray2.00A19-147[»]
4G4HX-ray2.00A19-147[»]
4GCBX-ray1.80A19-147[»]
4GCCX-ray2.00A19-147[»]
4GCDX-ray2.80A19-147[»]
4GCEX-ray2.90A19-147[»]
4GCFX-ray3.50A19-147[»]
4GLAX-ray2.75A/B19-147[»]
4GLVX-ray2.57A/C/E/G19-147[»]
4GN3X-ray1.95A/C/E/G/I/K/M/O/Q19-147[»]
4GN4X-ray1.86A19-147[»]
4GN5X-ray1.86C/D19-147[»]
4H1PX-ray2.30A19-147[»]
4H8XX-ray1.20A19-147[»]
4H8YX-ray1.20A19-147[»]
4H8ZX-ray1.20A19-147[»]
4H90X-ray1.20A19-147[»]
4H91X-ray1.20A19-147[»]
4H92X-ray1.20A19-147[»]
4H93X-ray1.20A19-147[»]
4H94X-ray1.20A19-147[»]
4H9AX-ray1.20A19-147[»]
4H9BX-ray1.20A19-147[»]
4H9CX-ray1.20A19-147[»]
4H9EX-ray1.20A19-147[»]
4H9FX-ray1.20A19-147[»]
4H9HX-ray1.20A19-147[»]
4H9IX-ray1.20A19-147[»]
4HP0X-ray1.19A19-147[»]
4HPIX-ray1.19A19-147[»]
4HSFX-ray1.82A19-147[»]
4HTKX-ray1.20A19-147[»]
4HTNX-ray1.30A19-147[»]
4HTQX-ray1.40A19-147[»]
4HV1X-ray2.30A19-147[»]
4HV2X-ray2.50A19-147[»]
4I8SX-ray2.00A19-147[»]
4IASX-ray2.60A19-147[»]
4IATX-ray2.00A19-147[»]
4II8X-ray1.88A19-147[»]
4J1AX-ray1.79A19-147[»]
4J1BX-ray1.66A19-147[»]
4J7VX-ray1.54A19-147[»]
4KXIX-ray2.00A19-147[»]
4LFPX-ray1.72A19-147[»]
4LFXX-ray2.10A19-147[»]
4LGKX-ray1.96A19-147[»]
4LYMX-ray2.10A19-147[»]
4LYOX-ray2.05A19-147[»]
4LYTX-ray1.90A/B19-147[»]
4LYZX-ray2.00A19-147[»]
4LZTX-ray0.95A19-147[»]
4M4OX-ray2.00A19-147[»]
4M6DX-ray2.68A/C/E/G/I/K19-147[»]
4MR1X-ray1.99A19-147[»]
4N5RX-ray2.10A19-147[»]
4N8ZX-ray1.20A19-147[»]
4NEBX-ray1.48A19-147[»]
4NFVX-ray1.63A19-147[»]
4NG1X-ray1.82A19-147[»]
4NG8X-ray1.09A19-147[»]
4NGIX-ray1.70A19-147[»]
4NGJX-ray1.10A19-147[»]
4NGKX-ray1.50A19-147[»]
4NGLX-ray1.52A19-147[»]
4NGOX-ray1.58A19-147[»]
4NGVX-ray1.64A19-147[»]
4NGWX-ray1.37A19-147[»]
4NGYX-ray1.35A19-147[»]
4NGZX-ray1.70A19-147[»]
4NY5X-ray1.85A19-147[»]
4O34X-ray2.09A19-147[»]
4OOOX-ray2.15A19-147[»]
4P2EX-ray1.60A19-147[»]
4QEQX-ray1.38A19-147[»]
5LYMX-ray1.80A/B19-147[»]
5LYTX-ray1.90A19-147[»]
5LYZX-ray2.00A19-147[»]
6LYTX-ray1.90A19-147[»]
6LYZX-ray2.00A19-147[»]
7LYZX-ray2.50A19-147[»]
8LYZX-ray2.50A19-147[»]
9LYZX-ray2.50A19-147[»]
ProteinModelPortaliP00698.
SMRiP00698. Positions 19-147.

Miscellaneous databases

EvolutionaryTraceiP00698.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG85133.
GeneTreeiENSGT00550000074398.
HOGENOMiHOG000037357.
HOVERGENiHBG052297.
InParanoidiP00698.
KOiK13915.
OMAiGNGMNAW.
OrthoDBiEOG7BW0M5.
PhylomeDBiP00698.
TreeFamiTF324882.

Family and domain databases

InterProiIPR001916. Glyco_hydro_22.
IPR019799. Glyco_hydro_22_CS.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
[Graphical view]
PfamiPF00062. Lys. 1 hit.
[Graphical view]
PRINTSiPR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTiSM00263. LYZ1. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
PROSITEiPS00128. LACTALBUMIN_LYSOZYME_1. 1 hit.
PS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P00698-1 [UniParc]FASTAAdd to Basket

« Hide

MRSLLILVLC FLPLAALGKV FGRCELAAAM KRHGLDNYRG YSLGNWVCAA    50
KFESNFNTQA TNRNTDGSTD YGILQINSRW WCNDGRTPGS RNLCNIPCSA 100
LLSSDITASV NCAKKIVSDG NGMNAWVAWR NRCKGTDVQA WIRGCRL 147
Length:147
Mass (Da):16,239
Last modified:July 21, 1986 - v1
Checksum:i81E85743FF579468
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti49 – 491A → V in CAA23711. 1 Publication
Sequence conflicti121 – 1211N → D AA sequence 1 Publication
Sequence conflicti124 – 1241N → S in CAA23711. 1 Publication
Sequence conflicti132 – 1321R → S in AAA48944. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
J00885 Genomic DNA. Translation: AAA48943.1.
V00428 mRNA. Translation: CAA23711.1.
AF410481 Genomic DNA. Translation: AAL69327.1.
M10640 mRNA. Translation: AAA48944.1.
PIRiA93859. LZCH.
RefSeqiNP_990612.1. NM_205281.1.
UniGeneiGga.713.

Genome annotation databases

EnsembliENSGALT00000016196; ENSGALP00000016177; ENSGALG00000009963.
GeneIDi396218.
KEGGigga:396218.

Cross-referencesi

Web resourcesi

Worthington enzyme manual

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
J00885 Genomic DNA. Translation: AAA48943.1 .
V00428 mRNA. Translation: CAA23711.1 .
AF410481 Genomic DNA. Translation: AAL69327.1 .
M10640 mRNA. Translation: AAA48944.1 .
PIRi A93859. LZCH.
RefSeqi NP_990612.1. NM_205281.1.
UniGenei Gga.713.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
132L X-ray 1.80 A 19-147 [» ]
193L X-ray 1.33 A 19-147 [» ]
194L X-ray 1.40 A 19-147 [» ]
1A2Y X-ray 1.50 C 19-147 [» ]
1AKI X-ray 1.50 A 19-147 [» ]
1AT5 X-ray 1.80 A 19-147 [» ]
1AT6 X-ray 1.80 A 19-147 [» ]
1AZF X-ray 1.80 A 19-147 [» ]
1B0D X-ray 1.84 A 19-147 [» ]
1B2K X-ray 1.60 A/B 19-147 [» ]
1BGI X-ray 1.70 A 19-147 [» ]
1BHZ X-ray 3.90 A 19-147 [» ]
1BVK X-ray 2.70 C/F 19-147 [» ]
1BVX X-ray 1.80 A 19-147 [» ]
1BWH X-ray 1.80 A 19-147 [» ]
1BWI X-ray 1.80 A 19-147 [» ]
1BWJ X-ray 1.80 A 19-147 [» ]
1C08 X-ray 2.30 C 19-147 [» ]
1C10 X-ray 2.03 A 19-147 [» ]
1DPW X-ray 1.64 A 19-147 [» ]
1DPX X-ray 1.65 A 19-147 [» ]
1DQJ X-ray 2.00 C 19-147 [» ]
1E8L NMR - A 19-147 [» ]
1F0W X-ray 1.90 A 19-147 [» ]
1F10 X-ray 1.70 A 19-147 [» ]
1F3J X-ray 3.10 P/Q 29-42 [» ]
1FDL X-ray 2.50 Y 19-147 [» ]
1FLQ X-ray 1.80 A 19-147 [» ]
1FLU X-ray 1.78 A 19-147 [» ]
1FLW X-ray 1.81 A 19-147 [» ]
1FLY X-ray 1.83 A 19-147 [» ]
1FN5 X-ray 1.78 A 19-147 [» ]
1G7H X-ray 1.85 C 19-147 [» ]
1G7I X-ray 1.80 C 19-147 [» ]
1G7J X-ray 1.75 C 19-147 [» ]
1G7L X-ray 2.00 C 19-147 [» ]
1G7M X-ray 1.90 C 19-147 [» ]
1GPQ X-ray 1.60 C/D 19-147 [» ]
1GWD X-ray 1.77 A 19-147 [» ]
1GXV NMR - 2 19-147 [» ]
1GXX NMR - A 19-147 [» ]
1H6M X-ray 1.64 A 19-147 [» ]
1H87 X-ray 1.72 A 19-147 [» ]
1HC0 X-ray 1.82 A 19-147 [» ]
1HEL X-ray 1.70 A 19-147 [» ]
1HEM X-ray 1.80 A 19-147 [» ]
1HEN X-ray 1.80 A 19-147 [» ]
1HEO X-ray 1.80 A 19-147 [» ]
1HEP X-ray 1.80 A 19-147 [» ]
1HEQ X-ray 1.80 A 19-147 [» ]
1HER X-ray 1.80 A 19-147 [» ]
1HEW X-ray 1.75 A 19-147 [» ]
1HF4 X-ray 1.45 A/B 19-147 [» ]
1HSW X-ray 2.00 A 19-147 [» ]
1HSX X-ray 1.90 A 19-147 [» ]
1IC4 X-ray 2.50 Y 19-147 [» ]
1IC5 X-ray 2.30 Y 19-147 [» ]
1IC7 X-ray 2.10 Y 19-147 [» ]
1IEE X-ray 0.94 A 19-147 [» ]
1IO5 neutron diffraction 2.00 A 19-147 [» ]
1IOQ X-ray 1.79 A 19-147 [» ]
1IOR X-ray 1.76 A 19-147 [» ]
1IOS X-ray 1.76 A 19-147 [» ]
1IOT X-ray 1.75 A 19-147 [» ]
1IR7 X-ray 1.90 A 19-147 [» ]
1IR8 X-ray 1.63 A 19-147 [» ]
1IR9 X-ray 1.90 A 19-147 [» ]
1J1O X-ray 1.80 Y 19-147 [» ]
1J1P X-ray 1.80 Y 19-147 [» ]
1J1X X-ray 1.80 Y 19-147 [» ]
1JA2 X-ray 2.87 A 19-147 [» ]
1JA4 X-ray 2.94 A 19-147 [» ]
1JA6 X-ray 2.96 A 19-147 [» ]
1JA7 X-ray 2.98 A 19-147 [» ]
1JIS X-ray 1.90 A 19-147 [» ]
1JIT X-ray 1.90 A 19-147 [» ]
1JIY X-ray 1.90 A 19-147 [» ]
1JJ0 X-ray 1.90 A 19-147 [» ]
1JJ1 X-ray 1.90 A 19-147 [» ]
1JJ3 X-ray 1.90 A/B 19-147 [» ]
1JPO X-ray 2.10 A 19-147 [» ]
1JTO X-ray 2.50 L/M 19-147 [» ]
1JTT X-ray 2.10 L 19-138 [» ]
1KIP X-ray 2.10 C 19-147 [» ]
1KIQ X-ray 1.85 C 19-147 [» ]
1KIR X-ray 2.00 C 19-147 [» ]
1KXW X-ray 1.96 A 19-147 [» ]
1KXX X-ray 1.71 A 19-147 [» ]
1KXY X-ray 1.79 A 19-147 [» ]
1LCN X-ray 1.63 A/B 19-147 [» ]
1LJ3 X-ray 2.00 A/B 19-147 [» ]
1LJ4 X-ray 1.95 A/B 19-147 [» ]
1LJE X-ray 2.00 A/B 19-147 [» ]
1LJF X-ray 1.80 A/B 19-147 [» ]
1LJG X-ray 1.90 A/B 19-147 [» ]
1LJH X-ray 1.80 A/B 19-147 [» ]
1LJI X-ray 2.00 A/B 19-147 [» ]
1LJJ X-ray 2.00 A/B 19-147 [» ]
1LJK X-ray 2.10 A/B 19-147 [» ]
1LKR X-ray 1.60 A/B 19-147 [» ]
1LKS X-ray 1.10 A 19-147 [» ]
1LMA X-ray 1.75 A 19-147 [» ]
1LPI X-ray 2.00 A 19-147 [» ]
1LSA X-ray 1.70 A 19-147 [» ]
1LSB X-ray 1.70 A 19-147 [» ]
1LSC X-ray 1.70 A 19-147 [» ]
1LSD X-ray 1.70 A 19-147 [» ]
1LSE X-ray 1.70 A 19-147 [» ]
1LSF X-ray 1.70 A 19-147 [» ]
1LSG X-ray 2.40 A 19-147 [» ]
1LSM X-ray 1.70 A 19-147 [» ]
1LSN X-ray 1.90 A 19-147 [» ]
1LSY X-ray 1.90 A 1-147 [» ]
1LSZ X-ray 2.00 A 1-147 [» ]
1LYO X-ray 1.93 A 19-147 [» ]
1LYS X-ray 1.72 A/B 19-147 [» ]
1LYZ X-ray 2.00 A 19-147 [» ]
1LZ8 X-ray 1.53 A 19-147 [» ]
1LZ9 X-ray 1.70 A 19-147 [» ]
1LZA X-ray 1.60 A 19-147 [» ]
1LZB X-ray 1.50 A 19-147 [» ]
1LZC X-ray 1.80 A 19-147 [» ]
1LZD X-ray 1.80 A 19-147 [» ]
1LZE X-ray 1.80 A 19-147 [» ]
1LZG X-ray 1.80 A 19-147 [» ]
1LZH X-ray 6.00 A/B 19-147 [» ]
1LZN neutron diffraction 1.70 A 19-147 [» ]
1LZT X-ray 1.97 A 19-147 [» ]
1MEL X-ray 2.50 L/M 19-147 [» ]
1MLC X-ray 2.50 E/F 19-147 [» ]
1N4F X-ray 1.78 A 19-147 [» ]
1NBY X-ray 1.80 C 19-147 [» ]
1NBZ X-ray 1.85 C 19-147 [» ]
1NDG X-ray 1.90 C 19-147 [» ]
1NDM X-ray 2.10 C 19-147 [» ]
1P2C X-ray 2.00 C/F 19-147 [» ]
1PS5 X-ray 2.00 A 19-147 [» ]
1QIO X-ray 1.20 A 19-147 [» ]
1QTK X-ray 2.03 A 19-147 [» ]
1RCM X-ray 1.90 A/B 19-147 [» ]
1RFP X-ray 1.75 A 19-147 [» ]
1RI8 X-ray 1.85 B 19-147 [» ]
1RJC X-ray 1.40 B 19-147 [» ]
1SF4 X-ray 2.98 A 19-147 [» ]
1SF6 X-ray 3.22 A 19-147 [» ]
1SF7 X-ray 3.22 A 19-147 [» ]
1SFB X-ray 3.22 A 19-147 [» ]
1SFG X-ray 3.22 A 19-147 [» ]
1SQ2 X-ray 1.45 L 19-147 [» ]
1T3P X-ray 1.60 A 19-147 [» ]
1T6V X-ray 1.70 L/M 19-147 [» ]
1UA6 X-ray 1.90 Y 19-147 [» ]
1UC0 X-ray 1.85 A 19-147 [» ]
1UCO X-ray 2.00 A/B 19-147 [» ]
1UIA X-ray 1.76 A 19-147 [» ]
1UIB X-ray 1.76 A 19-147 [» ]
1UIC X-ray 1.95 A 19-147 [» ]
1UID X-ray 1.95 A 19-147 [» ]
1UIE X-ray 1.95 A 19-147 [» ]
1UIF X-ray 1.85 A 19-147 [» ]
1UIG X-ray 1.95 A 19-147 [» ]
1UIH X-ray 1.75 A 19-147 [» ]
1UUZ X-ray 1.80 C/D 19-147 [» ]
1V7S X-ray 1.14 A 19-147 [» ]
1V7T X-ray 1.13 A/B 19-147 [» ]
1VAT X-ray 1.60 A 19-147 [» ]
1VAU X-ray 1.50 A 19-147 [» ]
1VDP X-ray 1.70 A/B 19-147 [» ]
1VDQ X-ray 1.50 A 19-147 [» ]
1VDS X-ray 1.60 A 19-147 [» ]
1VDT X-ray 1.70 A 19-147 [» ]
1VED X-ray 1.90 A 19-147 [» ]
1VFB X-ray 1.80 C 19-147 [» ]
1W6Z X-ray 1.65 A 19-147 [» ]
1WTM X-ray 1.33 A 19-147 [» ]
1WTN X-ray 1.13 A 19-147 [» ]
1XEI X-ray 2.10 A 19-147 [» ]
1XEJ X-ray 2.10 A 19-147 [» ]
1XEK X-ray 2.30 A 19-147 [» ]
1XFP X-ray 1.50 L 19-147 [» ]
1XGP X-ray 2.10 C 19-147 [» ]
1XGQ X-ray 2.10 C 19-147 [» ]
1XGR X-ray 2.10 C 19-147 [» ]
1XGT X-ray 2.10 C 19-147 [» ]
1XGU X-ray 2.10 C 19-147 [» ]
1YIK X-ray 1.75 A 19-147 [» ]
1YIL X-ray 1.60 A 19-147 [» ]
1YKX X-ray 1.90 X 19-147 [» ]
1YKY X-ray 1.90 X 19-147 [» ]
1YKZ X-ray 1.80 X 19-147 [» ]
1YL0 X-ray 1.90 X 19-147 [» ]
1YL1 X-ray 1.90 X 19-147 [» ]
1YQV X-ray 1.70 Y 19-147 [» ]
1Z55 X-ray 1.90 A 19-147 [» ]
1ZMY X-ray 3.00 L/M 19-147 [» ]
1ZV5 X-ray 2.00 L 19-147 [» ]
1ZVH X-ray 1.50 L 19-147 [» ]
1ZVY X-ray 1.63 B 19-147 [» ]
2A6U X-ray - A 19-147 [» ]
2A7D X-ray 1.66 A 19-147 [» ]
2A7F X-ray 1.85 A 19-147 [» ]
2AUB X-ray 1.70 A 19-147 [» ]
2B5Z X-ray 1.60 A 19-147 [» ]
2BLX X-ray 1.40 A 19-147 [» ]
2BLY X-ray 1.40 A 19-147 [» ]
2BPU X-ray 1.35 A 19-147 [» ]
2C8O X-ray 1.50 A 19-147 [» ]
2C8P X-ray 1.50 A 19-147 [» ]
2CDS X-ray 2.00 A 19-147 [» ]
2CGI X-ray 1.35 A 19-147 [» ]
2D4I X-ray 1.16 A/B 19-147 [» ]
2D4J X-ray 1.16 A 19-147 [» ]
2D4K X-ray 1.15 A/N 19-147 [» ]
2D6B X-ray 1.25 A 19-147 [» ]
2D91 X-ray 2.10 A 19-147 [» ]
2DQC X-ray 1.80 Y 19-147 [» ]
2DQD X-ray 1.80 Y 19-147 [» ]
2DQE X-ray 1.90 Y 19-147 [» ]
2DQF X-ray 2.50 C/F 19-147 [» ]
2DQG X-ray 2.30 Y 19-147 [» ]
2DQH X-ray 2.30 Y 19-147 [» ]
2DQI X-ray 2.00 Y 19-147 [» ]
2DQJ X-ray 1.80 Y 19-147 [» ]
2EIZ X-ray 1.90 C 19-147 [» ]
2EKS X-ray 2.00 C 19-147 [» ]
2EPE X-ray 2.50 A 19-147 [» ]
2F2N X-ray 1.60 A 19-147 [» ]
2F30 X-ray 1.65 A 19-147 [» ]
2F4A X-ray 1.95 A 19-147 [» ]
2F4G X-ray 1.65 A 19-147 [» ]
2FBB X-ray 1.46 A 19-147 [» ]
2G4P X-ray 1.84 A 19-147 [» ]
2G4Q X-ray 1.84 A 19-147 [» ]
2H9J X-ray 1.75 A 19-147 [» ]
2H9K X-ray 1.75 A 19-147 [» ]
2HFM model - Y 19-147 [» ]
2HS7 X-ray - A 19-147 [» ]
2HS9 X-ray - A 19-147 [» ]
2HSO X-ray - A 19-147 [» ]
2HTX X-ray 1.56 A 19-147 [» ]
2HU1 X-ray 1.63 A 19-147 [» ]
2HU3 X-ray 1.30 A 19-147 [» ]
2HUB X-ray 1.20 A 19-147 [» ]
2I25 X-ray 1.80 L/M 19-147 [» ]
2I26 X-ray 2.50 L/M/Q 19-147 [» ]
2I6Z X-ray 1.90 A 19-147 [» ]
2IFF X-ray 2.65 Y 19-147 [» ]
2LYM X-ray 2.00 A 19-147 [» ]
2LYO X-ray 1.93 A 19-147 [» ]
2LYZ X-ray 2.00 A 19-147 [» ]
2LZH X-ray 6.00 A 19-147 [» ]
2LZT X-ray 1.97 A 19-147 [» ]
2PC2 X-ray 1.54 A 19-147 [» ]
2Q0M X-ray 1.70 X 19-147 [» ]
2VB1 X-ray 0.65 A 19-147 [» ]
2W1L X-ray 1.51 A 19-147 [» ]
2W1M X-ray 1.78 A 19-147 [» ]
2W1X X-ray 1.70 A 19-147 [» ]
2W1Y X-ray 1.73 A 19-147 [» ]
2WAR X-ray 1.80 A 19-147 [» ]
2X0A X-ray 1.52 A 19-147 [» ]
2XBR X-ray 1.29 A 19-147 [» ]
2XBS X-ray 1.37 A 19-147 [» ]
2XJW X-ray 1.67 A 19-147 [» ]
2XTH X-ray 1.80 A 19-147 [» ]
2YBH X-ray 2.00 A 19-147 [» ]
2YBI X-ray 2.00 A 19-147 [» ]
2YBJ X-ray 2.00 A 19-147 [» ]
2YBL X-ray 2.00 A 19-147 [» ]
2YBM X-ray 2.00 A 19-147 [» ]
2YBN X-ray 2.00 A 19-147 [» ]
2YDG X-ray 2.00 A 19-147 [» ]
2YSS X-ray 2.40 C 19-147 [» ]
2YVB X-ray 1.62 A 19-147 [» ]
2Z12 X-ray 1.15 A 19-147 [» ]
2Z18 X-ray 1.15 A 19-147 [» ]
2Z19 X-ray 1.15 A 19-147 [» ]
2ZNW X-ray 2.71 Y/Z 19-147 [» ]
2ZNX X-ray 2.30 Y/Z 19-147 [» ]
2ZQ3 X-ray 1.60 A 19-147 [» ]
2ZQ4 X-ray 2.00 A 19-147 [» ]
2ZYP X-ray 1.18 A 19-147 [» ]
3A34 X-ray 1.65 A 19-147 [» ]
3A3Q X-ray 2.00 A 19-147 [» ]
3A3R X-ray 1.90 X 19-147 [» ]
3A67 X-ray 1.80 Y 19-147 [» ]
3A6B X-ray 1.80 Y 19-147 [» ]
3A6C X-ray 1.80 Y 19-147 [» ]
3A8Z X-ray 1.40 A 19-147 [» ]
3A90 X-ray 1.45 A 19-147 [» ]
3A91 X-ray 1.55 A 19-147 [» ]
3A92 X-ray 1.50 A 19-147 [» ]
3A93 X-ray 1.55 A 19-147 [» ]
3A94 X-ray 1.55 A 19-147 [» ]
3A95 X-ray 1.50 A 19-147 [» ]
3A96 X-ray 1.75 A 19-147 [» ]
3AGG X-ray 1.60 G 19-147 [» ]
3AGH X-ray 1.49 A 19-147 [» ]
3AGI X-ray 1.20 A 19-147 [» ]
3AJN X-ray 1.05 A 19-147 [» ]
3ATN X-ray 1.17 A 19-147 [» ]
3ATO X-ray 1.17 A 19-147 [» ]
3AW6 X-ray 2.10 A 19-147 [» ]
3AW7 X-ray 2.10 A 19-147 [» ]
3AZ4 X-ray 1.62 A 19-147 [» ]
3AZ5 X-ray 2.34 A 19-147 [» ]
3AZ6 X-ray 1.50 A 19-147 [» ]
3AZ7 X-ray 2.10 A 19-147 [» ]
3B6L X-ray 2.30 A 1-147 [» ]
3B72 X-ray 1.50 A 1-147 [» ]
3D9A X-ray 1.20 C 19-147 [» ]
3E3D X-ray 1.55 A 19-147 [» ]
3EMS X-ray 1.65 A 19-147 [» ]
3EXD X-ray 1.49 A 19-147 [» ]
3F6Z X-ray 2.50 A/C 19-147 [» ]
3G3A X-ray 2.20 B/D/F/H 19-147 [» ]
3G3B X-ray 2.40 B/D/F/H 19-147 [» ]
3HFM X-ray 3.00 Y 19-147 [» ]
3IJU X-ray 1.60 A 19-147 [» ]
3IJV X-ray 1.70 A 19-147 [» ]
3J4G electron microscopy 2.90 A 19-147 [» ]
3KAM X-ray 1.59 A 19-147 [» ]
3LYM X-ray 2.00 A 19-147 [» ]
3LYO X-ray 1.93 A 19-147 [» ]
3LYT X-ray 1.90 A/B 19-147 [» ]
3LYZ X-ray 2.00 A 19-147 [» ]
3LZT X-ray 0.93 A 19-147 [» ]
3M18 X-ray 1.95 B 19-147 [» ]
3M3U X-ray 2.35 A 19-147 [» ]
3MBE X-ray 2.89 P/Q 29-45 [» ]
3N9A X-ray 1.40 A 19-147 [» ]
3N9C X-ray 1.50 A 19-147 [» ]
3N9E X-ray 1.38 A 19-147 [» ]
3OJP X-ray 1.81 A 19-147 [» ]
3OK0 X-ray 1.82 A 19-147 [» ]
3OTP X-ray 3.76 G/H/I/J/K/L 36-76 [» ]
3P4Z X-ray 1.60 A 19-147 [» ]
3P64 X-ray 1.30 A 19-147 [» ]
3P65 X-ray 2.10 A 19-147 [» ]
3P66 X-ray 1.36 A 19-147 [» ]
3P68 X-ray 1.60 A 19-147 [» ]
3QE8 X-ray 1.49 A/B 19-147 [» ]
3QNG X-ray 1.55 A 19-147 [» ]
3QY4 X-ray 1.65 A 19-146 [» ]
3RNX X-ray 1.86 A 19-147 [» ]
3RT5 X-ray 1.75 X 19-147 [» ]
3RU5 X-ray 1.35 A 19-147 [» ]
3RW8 X-ray 1.86 A 19-147 [» ]
3RZ4 X-ray 1.80 A 19-147 [» ]
3SP3 X-ray 1.80 A 19-147 [» ]
3T6U X-ray 2.21 A 19-147 [» ]
3TMU X-ray 1.90 A 1-147 [» ]
3TMV X-ray 1.90 A 1-147 [» ]
3TMW X-ray 1.90 A 1-147 [» ]
3TMX X-ray 1.90 A 1-147 [» ]
3TXB X-ray 1.59 A 19-147 [» ]
3TXD X-ray 1.53 A 19-147 [» ]
3TXE X-ray 1.70 A 19-147 [» ]
3TXF X-ray 1.69 A 19-147 [» ]
3TXG X-ray 1.70 A 19-147 [» ]
3TXH X-ray 1.69 A 19-147 [» ]
3TXI X-ray 1.60 A 19-147 [» ]
3TXJ X-ray 2.48 A 19-147 [» ]
3TXK X-ray 3.00 A 19-147 [» ]
3ULR X-ray 1.65 A 19-147 [» ]
3VFX X-ray 1.95 A/B 19-147 [» ]
3W6A X-ray 1.77 A 19-147 [» ]
3ZEK X-ray 1.43 A 19-147 [» ]
3ZVQ X-ray 2.00 A 19-88 [» ]
B 90-147 [» ]
4A7D X-ray 1.50 A 19-147 [» ]
4A8A electron microscopy 14.20 M 19-147 [» ]
4A8B electron microscopy 13.00 M/N/O/P/Q/R 19-147 [» ]
4AGA X-ray 1.50 A 19-147 [» ]
4AXT X-ray 1.10 A 19-147 [» ]
4B0D X-ray 1.10 A 19-147 [» ]
4B1A X-ray 1.67 A 19-147 [» ]
4B49 X-ray 1.15 A 19-147 [» ]
4B4E X-ray 1.00 A 19-147 [» ]
4B4I X-ray 1.20 A 19-147 [» ]
4B4J X-ray 1.25 A 19-147 [» ]
4BAD X-ray 1.35 A 19-147 [» ]
4BAF X-ray 1.51 A 19-147 [» ]
4BAP X-ray 1.21 A 19-147 [» ]
4BS7 X-ray 1.70 A 19-147 [» ]
4CJ2 X-ray 1.50 A/B 1-147 [» ]
4D9Z X-ray 1.71 A 19-147 [» ]
4DC4 X-ray 2.65 A/B/C 19-147 [» ]
4DD0 X-ray 1.70 A 19-147 [» ]
4DD1 X-ray 1.70 A/B 19-147 [» ]
4DD2 X-ray 1.55 A 19-147 [» ]
4DD3 X-ray 1.70 A 19-147 [» ]
4DD4 X-ray 1.70 A 19-147 [» ]
4DD6 X-ray 1.70 A 19-147 [» ]
4DD7 X-ray 1.60 A 19-147 [» ]
4DD9 X-ray 1.60 A 19-147 [» ]
4DDA X-ray 2.48 A 19-147 [» ]
4DDB X-ray 3.00 A 19-147 [» ]
4DDC X-ray 1.80 A/B 19-147 [» ]
4DT3 X-ray 1.80 A 19-147 [» ]
4E3U X-ray 1.50 A 19-147 [» ]
4EOF X-ray 1.83 A 19-147 [» ]
4ET8 X-ray 1.90 A 19-147 [» ]
4ET9 X-ray 1.90 A 19-147 [» ]
4ETA X-ray 1.91 A 19-147 [» ]
4ETB X-ray 1.91 A 19-147 [» ]
4ETC X-ray 1.91 A 19-147 [» ]
4ETD X-ray 1.90 A 19-147 [» ]
4ETE X-ray 1.90 A 19-147 [» ]
4FJR X-ray 1.86 A 19-147 [» ]
4G49 X-ray 2.40 A 19-147 [» ]
4G4A X-ray 2.40 A 19-147 [» ]
4G4B X-ray 2.10 A 19-147 [» ]
4G4C X-ray 2.00 A 19-147 [» ]
4G4H X-ray 2.00 A 19-147 [» ]
4GCB X-ray 1.80 A 19-147 [» ]
4GCC X-ray 2.00 A 19-147 [» ]
4GCD X-ray 2.80 A 19-147 [» ]
4GCE X-ray 2.90 A 19-147 [» ]
4GCF X-ray 3.50 A 19-147 [» ]
4GLA X-ray 2.75 A/B 19-147 [» ]
4GLV X-ray 2.57 A/C/E/G 19-147 [» ]
4GN3 X-ray 1.95 A/C/E/G/I/K/M/O/Q 19-147 [» ]
4GN4 X-ray 1.86 A 19-147 [» ]
4GN5 X-ray 1.86 C/D 19-147 [» ]
4H1P X-ray 2.30 A 19-147 [» ]
4H8X X-ray 1.20 A 19-147 [» ]
4H8Y X-ray 1.20 A 19-147 [» ]
4H8Z X-ray 1.20 A 19-147 [» ]
4H90 X-ray 1.20 A 19-147 [» ]
4H91 X-ray 1.20 A 19-147 [» ]
4H92 X-ray 1.20 A 19-147 [» ]
4H93 X-ray 1.20 A 19-147 [» ]
4H94 X-ray 1.20 A 19-147 [» ]
4H9A X-ray 1.20 A 19-147 [» ]
4H9B X-ray 1.20 A 19-147 [» ]
4H9C X-ray 1.20 A 19-147 [» ]
4H9E X-ray 1.20 A 19-147 [» ]
4H9F X-ray 1.20 A 19-147 [» ]
4H9H X-ray 1.20 A 19-147 [» ]
4H9I X-ray 1.20 A 19-147 [» ]
4HP0 X-ray 1.19 A 19-147 [» ]
4HPI X-ray 1.19 A 19-147 [» ]
4HSF X-ray 1.82 A 19-147 [» ]
4HTK X-ray 1.20 A 19-147 [» ]
4HTN X-ray 1.30 A 19-147 [» ]
4HTQ X-ray 1.40 A 19-147 [» ]
4HV1 X-ray 2.30 A 19-147 [» ]
4HV2 X-ray 2.50 A 19-147 [» ]
4I8S X-ray 2.00 A 19-147 [» ]
4IAS X-ray 2.60 A 19-147 [» ]
4IAT X-ray 2.00 A 19-147 [» ]
4II8 X-ray 1.88 A 19-147 [» ]
4J1A X-ray 1.79 A 19-147 [» ]
4J1B X-ray 1.66 A 19-147 [» ]
4J7V X-ray 1.54 A 19-147 [» ]
4KXI X-ray 2.00 A 19-147 [» ]
4LFP X-ray 1.72 A 19-147 [» ]
4LFX X-ray 2.10 A 19-147 [» ]
4LGK X-ray 1.96 A 19-147 [» ]
4LYM X-ray 2.10 A 19-147 [» ]
4LYO X-ray 2.05 A 19-147 [» ]
4LYT X-ray 1.90 A/B 19-147 [» ]
4LYZ X-ray 2.00 A 19-147 [» ]
4LZT X-ray 0.95 A 19-147 [» ]
4M4O X-ray 2.00 A 19-147 [» ]
4M6D X-ray 2.68 A/C/E/G/I/K 19-147 [» ]
4MR1 X-ray 1.99 A 19-147 [» ]
4N5R X-ray 2.10 A 19-147 [» ]
4N8Z X-ray 1.20 A 19-147 [» ]
4NEB X-ray 1.48 A 19-147 [» ]
4NFV X-ray 1.63 A 19-147 [» ]
4NG1 X-ray 1.82 A 19-147 [» ]
4NG8 X-ray 1.09 A 19-147 [» ]
4NGI X-ray 1.70 A 19-147 [» ]
4NGJ X-ray 1.10 A 19-147 [» ]
4NGK X-ray 1.50 A 19-147 [» ]
4NGL X-ray 1.52 A 19-147 [» ]
4NGO X-ray 1.58 A 19-147 [» ]
4NGV X-ray 1.64 A 19-147 [» ]
4NGW X-ray 1.37 A 19-147 [» ]
4NGY X-ray 1.35 A 19-147 [» ]
4NGZ X-ray 1.70 A 19-147 [» ]
4NY5 X-ray 1.85 A 19-147 [» ]
4O34 X-ray 2.09 A 19-147 [» ]
4OOO X-ray 2.15 A 19-147 [» ]
4P2E X-ray 1.60 A 19-147 [» ]
4QEQ X-ray 1.38 A 19-147 [» ]
5LYM X-ray 1.80 A/B 19-147 [» ]
5LYT X-ray 1.90 A 19-147 [» ]
5LYZ X-ray 2.00 A 19-147 [» ]
6LYT X-ray 1.90 A 19-147 [» ]
6LYZ X-ray 2.00 A 19-147 [» ]
7LYZ X-ray 2.50 A 19-147 [» ]
8LYZ X-ray 2.50 A 19-147 [» ]
9LYZ X-ray 2.50 A 19-147 [» ]
ProteinModelPortali P00698.
SMRi P00698. Positions 19-147.
ModBasei Search...

Protein-protein interaction databases

BioGridi 676478. 2 interactions.
IntActi P00698. 4 interactions.

Chemistry

ChEMBLi CHEMBL1932892.
DrugBanki DB00128. L-Aspartic Acid.

Protein family/group databases

Allergomei 3294. Gal d 4.0101.
362. Gal d 4.
CAZyi GH22. Glycoside Hydrolase Family 22.

Proteomic databases

PaxDbi P00698.
PRIDEi P00698.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSGALT00000016196 ; ENSGALP00000016177 ; ENSGALG00000009963 .
GeneIDi 396218.
KEGGi gga:396218.

Organism-specific databases

CTDi 4069.

Phylogenomic databases

eggNOGi NOG85133.
GeneTreei ENSGT00550000074398.
HOGENOMi HOG000037357.
HOVERGENi HBG052297.
InParanoidi P00698.
KOi K13915.
OMAi GNGMNAW.
OrthoDBi EOG7BW0M5.
PhylomeDBi P00698.
TreeFami TF324882.

Enzyme and pathway databases

Reactomei REACT_197049. Amyloids.
SABIO-RK P00698.

Miscellaneous databases

EvolutionaryTracei P00698.
NextBioi 20816270.
PROi P00698.

Family and domain databases

InterProi IPR001916. Glyco_hydro_22.
IPR019799. Glyco_hydro_22_CS.
IPR000974. Glyco_hydro_22_lys.
IPR023346. Lysozyme-like_dom.
[Graphical view ]
Pfami PF00062. Lys. 1 hit.
[Graphical view ]
PRINTSi PR00137. LYSOZYME.
PR00135. LYZLACT.
SMARTi SM00263. LYZ1. 1 hit.
[Graphical view ]
SUPFAMi SSF53955. SSF53955. 1 hit.
PROSITEi PS00128. LACTALBUMIN_LYSOZYME_1. 1 hit.
PS51348. LACTALBUMIN_LYSOZYME_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Exons encode functional and structural units of chicken lysozyme."
    Jung A., Sippel A.E., Grez M., Schutz G.
    Proc. Natl. Acad. Sci. U.S.A. 77:5759-5763(1980) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SEQUENCE REVISION TO 121.
  2. "The chicken lysozyme chromatin domain contains a second, widely expressed gene."
    Chong S., Riggs A.D., Bonifer C.
    Nucleic Acids Res. 30:463-467(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Precursor of egg white lysozyme. Amino acid sequence of an NH2-terminal extension."
    Palmiter R.D., Gagnon J., Ericsson L.H., Walsh K.A.
    J. Biol. Chem. 252:6386-6393(1977) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-20.
  4. "The amino acid sequence of egg white lysozyme."
    Canfield R.E.
    J. Biol. Chem. 238:2698-2707(1963) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 19-147.
  5. "Isolation of recombinant plasmids bearing cDNA to hen ovomucoid and lysozyme mRNAs."
    Buell G.N., Wickens M.P., Carbon J., Schimke R.T.
    J. Biol. Chem. 254:9277-9283(1979) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 123-146.
  6. "The disulfide bonds of egg white lysozyme (muramidase)."
    Canfield R.E., Liu A.K.
    J. Biol. Chem. 240:1997-2002(1965) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISULFIDE BONDS.
  7. "The disulfide bridges of hen's egg-white lysozyme."
    Jauregui-Adell J., Jolles J., Jolles P.
    Biochim. Biophys. Acta 107:97-111(1965) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISULFIDE BONDS.
  8. "Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white."
    Maehashi K., Matano M., Irisawa T., Uchino M., Kashiwagi Y., Watanabe T.
    Gene 492:244-249(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  9. "Vertebrate lysozymes."
    Imoto T., Johnson L.N., North A.C.T., Phillips D.C., Rupley J.A.
    (In) Boyer P.D. (eds.); The enzymes (3rd ed.), pp.7:665-868, Academic Press, New York (1972)
    Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS), REVIEW.
  10. "Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2-A resolution."
    Blake C.C.F., Koenig D.F., Mair G.A., North A.C.T., Phillips D.C., Sarma V.R.
    Nature 206:757-761(1965) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS).
  11. Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF TRICLINIC LYSOZYME.
  12. "Structures of triclinic mono- and di-N-acetylglucosamine: lysozyme complexes -- a crystallographic study."
    Kurachi K., Sieker L.C., Jensen L.H.
    J. Mol. Biol. 101:11-24(1976) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF TRICLINIC LYSOZYME.
  13. "Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-A resolution."
    Fischmann T.O., Bentley G.A., Bhat T.N., Boulot G., Mariuzza R.A., Phillips S.E., Tello D., Poljak R.J.
    J. Biol. Chem. 266:12915-12920(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF COMPLEX WITH ANTIBODY.
  14. "Sequential 1H NMR assignments and secondary structure of hen egg white lysozyme in solution."
    Redfield C., Dobson C.M.
    Biochemistry 27:122-136(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR.
  15. "Structural and dynamical properties of a denatured protein. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8 M urea."
    Schwalbe H., Fiebig K.M., Buck M., Jones J.A., Grimshaw S.B., Spencer A., Glaser S.J., Smith L.J., Dobson C.M.
    Biochemistry 36:8977-8991(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR.
  16. "Conversion of Trp 62 of hen egg-white lysozyme to Tyr by site-directed mutagenesis."
    Kumagai I., Kojima S., Tamaki E., Miura K.
    J. Biochem. 102:733-740(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: MUTAGENESIS.

Entry informationi

Entry nameiLYSC_CHICK
AccessioniPrimary (citable) accession number: P00698
Secondary accession number(s): Q90884
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: September 3, 2014
This is version 162 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

Lysozyme C is capable of both hydrolysis and transglycosylation; it shows also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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