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P00694

- XYNA_BACPU

UniProt

P00694 - XYNA_BACPU

Protein

Endo-1,4-beta-xylanase A

Gene

xynA

Organism
Bacillus pumilus (Bacillus mesentericus)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 2 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei120 – 1201NucleophilePROSITE-ProRule annotation
    Active sitei209 – 2091Proton donorPROSITE-ProRule annotation

    GO - Molecular functioni

    1. endo-1,4-beta-xylanase activity Source: UniProtKB-EC

    GO - Biological processi

    1. xylan catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

    Enzyme and pathway databases

    UniPathwayiUPA00114.

    Protein family/group databases

    CAZyiGH11. Glycoside Hydrolase Family 11.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endo-1,4-beta-xylanase A (EC:3.2.1.8)
    Short name:
    Xylanase A
    Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase A
    Gene namesi
    Name:xynA
    OrganismiBacillus pumilus (Bacillus mesentericus)
    Taxonomic identifieri1408 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi120 – 1201E → S: Loss of activity. 1 Publication
    Mutagenesisi209 – 2091E → D: Loss of activity. 1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2727Add
    BLAST
    Chaini28 – 228201Endo-1,4-beta-xylanase APRO_0000007997Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP00694.
    SMRiP00694. Positions 27-227.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.60.120.180. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR001137. Glyco_hydro_11.
    IPR013319. Glyco_hydro_11/12.
    IPR018208. Glyco_hydro_11_AS.
    [Graphical view]
    PfamiPF00457. Glyco_hydro_11. 1 hit.
    [Graphical view]
    PRINTSiPR00911. GLHYDRLASE11.
    SUPFAMiSSF49899. SSF49899. 1 hit.
    PROSITEiPS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
    PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P00694-1 [UniParc]FASTAAdd to Basket

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    MNLRKLRLLF VMCIGLTLIL TAVPAHARTI TNNEMGNHSG YDYELWKDYG    50
    NTSMTLNNGG AFSAGWNNIG NALFRKGKKF DSTRTHHQLG NISINYNASF 100
    NPGGNSYLCV YGWTQSPLAE YYIVDSWGTY RPTGAYKGSF YADGGTYDIY 150
    ETTRVNQPSI IGIATFKQYW SVRQTKRTSG TVSVSAHFRK WESLGMPMGK 200
    MYETAFTVEG YQSSGSANVM TNQLFIGN 228
    Length:228
    Mass (Da):25,491
    Last modified:February 1, 1996 - v2
    Checksum:i32EF9833E7B5E503
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X00660 Genomic DNA. Translation: CAA25278.1.
    PIRiA00848. WWBSXP.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X00660 Genomic DNA. Translation: CAA25278.1 .
    PIRi A00848. WWBSXP.

    3D structure databases

    ProteinModelPortali P00694.
    SMRi P00694. Positions 27-227.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH11. Glycoside Hydrolase Family 11.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00114 .

    Family and domain databases

    Gene3Di 2.60.120.180. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR001137. Glyco_hydro_11.
    IPR013319. Glyco_hydro_11/12.
    IPR018208. Glyco_hydro_11_AS.
    [Graphical view ]
    Pfami PF00457. Glyco_hydro_11. 1 hit.
    [Graphical view ]
    PRINTSi PR00911. GLHYDRLASE11.
    SUPFAMi SSF49899. SSF49899. 1 hit.
    PROSITEi PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
    PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete nucleotide sequence of the xylanase gene (xynA) of Bacillus pumilus."
      Fukusaki E., Panbangred W., Shinmyo A., Okada H.
      FEBS Lett. 171:197-201(1984)
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: IPO.
    2. Urabe I.
      Submitted (FEB-1991) to the EMBL/GenBank/DDBJ databases
      Cited for: SEQUENCE REVISION TO 103.
    3. "Site-directed mutagenesis at aspartate and glutamate residues of xylanase from Bacillus pumilus."
      Ko E.P., Akatsuka H., Moriyama H., Shinmyo A., Hata Y., Katsube Y., Urabe I., Okada H.
      Biochem. J. 288:117-121(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: MUTAGENESIS, ACTIVE SITES.

    Entry informationi

    Entry nameiXYNA_BACPU
    AccessioniPrimary (citable) accession number: P00694
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 21, 1986
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 83 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3