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P00694 (XYNA_BACPU) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endo-1,4-beta-xylanase A

Short name=Xylanase A
EC=3.2.1.8
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase A
Gene names
Name:xynA
OrganismBacillus pumilus (Bacillus mesentericus)
Taxonomic identifier1408 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length228 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathway

Glycan degradation; xylan degradation.

Sequence similarities

Belongs to the glycosyl hydrolase 11 (cellulase G) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Polysaccharide degradation
Xylan degradation
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processxylan catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionendo-1,4-beta-xylanase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727
Chain28 – 228201Endo-1,4-beta-xylanase A
PRO_0000007997

Sites

Active site1201Nucleophile By similarity
Active site2091Proton donor By similarity

Experimental info

Mutagenesis1201E → S: Loss of activity.
Mutagenesis2091E → D: Loss of activity.

Sequences

Sequence LengthMass (Da)Tools
P00694 [UniParc].

Last modified February 1, 1996. Version 2.
Checksum: 32EF9833E7B5E503

FASTA22825,491
        10         20         30         40         50         60 
MNLRKLRLLF VMCIGLTLIL TAVPAHARTI TNNEMGNHSG YDYELWKDYG NTSMTLNNGG 

        70         80         90        100        110        120 
AFSAGWNNIG NALFRKGKKF DSTRTHHQLG NISINYNASF NPGGNSYLCV YGWTQSPLAE 

       130        140        150        160        170        180 
YYIVDSWGTY RPTGAYKGSF YADGGTYDIY ETTRVNQPSI IGIATFKQYW SVRQTKRTSG 

       190        200        210        220 
TVSVSAHFRK WESLGMPMGK MYETAFTVEG YQSSGSANVM TNQLFIGN 

« Hide

References

[1]"The complete nucleotide sequence of the xylanase gene (xynA) of Bacillus pumilus."
Fukusaki E., Panbangred W., Shinmyo A., Okada H.
FEBS Lett. 171:197-201(1984)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: IPO.
[2]Urabe I.
Submitted (FEB-1991) to the EMBL/GenBank/DDBJ databases
Cited for: SEQUENCE REVISION TO 103.
[3]"Site-directed mutagenesis at aspartate and glutamate residues of xylanase from Bacillus pumilus."
Ko E.P., Akatsuka H., Moriyama H., Shinmyo A., Hata Y., Katsube Y., Urabe I., Okada H.
Biochem. J. 288:117-121(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: MUTAGENESIS, ACTIVE SITES.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X00660 Genomic DNA. Translation: CAA25278.1.
PIRWWBSXP. A00848.

3D structure databases

ProteinModelPortalP00694.
SMRP00694. Positions 27-227.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH11. Glycoside Hydrolase Family 11.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00114.

Family and domain databases

Gene3D2.60.120.180. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR001137. Glyco_hydro_11.
IPR013319. Glyco_hydro_11/12.
IPR018208. Glyco_hydro_11_AS.
[Graphical view]
PfamPF00457. Glyco_hydro_11. 1 hit.
[Graphical view]
PRINTSPR00911. GLHYDRLASE11.
SUPFAMSSF49899. SSF49899. 1 hit.
PROSITEPS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYNA_BACPU
AccessionPrimary (citable) accession number: P00694
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: February 1, 1996
Last modified: November 13, 2013
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries