P00638 (EXRN_BPT7) Reviewed, UniProtKB/Swiss-Prot
Last modified
September 21, 2011.
Version 56.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Exodeoxyribonuclease Short name=Exonuclease EC=3.1.11.3 | ||
| Gene names |
| ||
| Organism | Enterobacteria phage T7 (Bacteriophage T7) | ||
| Taxonomic identifier | 10760 [NCBI] | ||
| Taxonomic lineage | Viruses › dsDNA viruses, no RNA stage › Caudovirales › Podoviridae › Autographivirinae › T7-like viruses | ||
| Virus host | Escherichia coli [TaxID: 562] |
Protein attributes
| Sequence length | 300 AA. |
| Sequence status | Complete. |
| Protein existence | Predicted |
General annotation (Comments)
| Function | This enzyme is essential for phage DNA replication; it is believed to function in the removal of DNA-linked RNA primers. It is also necessary for host DNA degradation and phage genetic recombination. |
| Catalytic activity | Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Exonuclease Hydrolase Nuclease |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Molecular function | 5'-3' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 300 | 300 | Exodeoxyribonuclease | PRO_0000106505 | |||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Complete nucleotide sequence of bacteriophage T7 DNA and the locations of T7 genetic elements." Dunn J.J., Studier F.W. J. Mol. Biol. 166:477-535(1983) [PubMed: 6864790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [2] | Dunn J.J. Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | V01146 Genomic DNA. Translation: CAA24418.1. |
| PIR | NDBPT7. S42316. |
| RefSeq | NP_041988.1. NC_001604.1. |
3D structure databases | |
| ProteinModelPortal | P00638. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1261052. |
Phylogenomic databases | |
| ProtClustDB | PHA0439. |
Family and domain databases | |
| InterPro | IPR020046. 5-3_exonucl_a-hlix_arch_N. [Graphical view] |
| Pfam | PF02739. 5_3_exonuc_N. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | EXRN_BPT7 | ||||||||
| Accession | Primary (citable) accession number: P00638 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Viral Protein Annotation Program | ||||||||

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