##gff-version 3
P00376	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7115669;Dbxref=PMID:7115669	
P00376	UniProtKB	Chain	2	187	.	.	.	ID=PRO_0000186361;Note=Dihydrofolate reductase	
P00376	UniProtKB	Domain	4	185	.	.	.	Note=DHFR;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00660	
P00376	UniProtKB	Binding site	10	10	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P00374	
P00376	UniProtKB	Binding site	16	22	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P00374	
P00376	UniProtKB	Binding site	31	36	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P00374	
P00376	UniProtKB	Binding site	55	57	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P00374	
P00376	UniProtKB	Binding site	71	71	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P00374	
P00376	UniProtKB	Binding site	77	79	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P00374	
P00376	UniProtKB	Binding site	117	124	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P00374	
P00376	UniProtKB	Sequence conflict	22	22	.	.	.	Note=D->N;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P00376	UniProtKB	Sequence conflict	102	102	.	.	.	Note=E->Q;Ontology_term=ECO:0000305;evidence=ECO:0000305