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Protein

Pollen allergen Amb a 3

Gene
N/A
Organism
Ambrosia artemisiifolia var. elatior (Short ragweed) (Ambrosia elatior)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Pollen allergen Amb a 3
Alternative name(s):
Allergen Amb a III
Allergen Ra3
Allergen: Amb a 3
OrganismiAmbrosia artemisiifolia var. elatior (Short ragweed) (Ambrosia elatior)
Taxonomic identifieri4215 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeHeliantheae allianceHeliantheaeAmbrosia

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei27. Amb a 3.
3068. Amb a 3.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 101101Pollen allergen Amb a 3PRO_0000085558Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi41 – 411N-linked (GlcNAc...)1 Publication
Disulfide bondi61 ↔ 881 Publication
Glycosylationi84 – 841O-linked (Hex)1 Publication
Modified residuei97 – 971Cysteine derivative
Modified residuei101 – 1011Blocked carboxyl end (Arg)

Post-translational modificationi

The identity of the saccharide is not reported (PubMed:7459340). The sugar attached to Ser-84 is represented simply as Hex.1 Publication
Cys-97 sulfhydryl group is modified but does not form an interchain disulfide bond.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliP00304.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 101100PhytocyaninPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 phytocyanin domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di2.60.40.420. 1 hit.
InterProiIPR008972. Cupredoxin.
IPR003245. Plcyanin-like.
[Graphical view]
PfamiPF02298. Cu_bind_like. 1 hit.
[Graphical view]
ProDomiPD003122. Plcyanin-like. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF49503. SSF49503. 1 hit.
PROSITEiPS51485. PHYTOCYANIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P00304-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GKVYLVGGPE LGGWKLQSDP RAYALWSARQ QFKTTDVLWF NFTTGEDSVA
60 70 80 90 100
EVWREEAYHA CDIKDPIRLE PGGPDRFTLL TPGSHFICTK DQKFVACVPG

R
Length:101
Mass (Da):11,375
Last modified:October 1, 1993 - v2
Checksum:i3CBD6721B85C01DD
GO

Sequence databases

PIRiA00313. ARRA3.

Cross-referencesi

Sequence databases

PIRiA00313. ARRA3.

3D structure databases

ProteinModelPortaliP00304.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei27. Amb a 3.
3068. Amb a 3.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.420. 1 hit.
InterProiIPR008972. Cupredoxin.
IPR003245. Plcyanin-like.
[Graphical view]
PfamiPF02298. Cu_bind_like. 1 hit.
[Graphical view]
ProDomiPD003122. Plcyanin-like. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF49503. SSF49503. 1 hit.
PROSITEiPS51485. PHYTOCYANIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: PROTEIN SEQUENCE, DISULFIDE BOND, GLYCOSYLATION AT ASN-41 AND SER-84.
    Tissue: Pollen.

Entry informationi

Entry nameiMPAA3_AMBEL
AccessioniPrimary (citable) accession number: P00304
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: October 1, 1993
Last modified: March 4, 2015
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.