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P00304 (MPAA3_AMBEL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pollen allergen Amb a 3
Alternative name(s):
Allergen Amb a III
Allergen Ra3
Allergen=Amb a 3
OrganismAmbrosia artemisiifolia var. elatior (Short ragweed) (Ambrosia elatior)
Taxonomic identifier4215 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeAsteroideaeHeliantheae allianceHeliantheaeAmbrosia

Protein attributes

Sequence length101 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Post-translational modification

The identity of the saccharide is not reported (Ref.1). The sugar attached to Ser-84 is represented simply as Hex.

Cys-97 sulfhydryl group is modified but does not form an interchain disulfide bond (Ref.1).

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Contains 1 phytocyanin domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 101101Pollen allergen Amb a 3
PRO_0000085558

Regions

Domain2 – 101100Phytocyanin

Amino acid modifications

Modified residue971Cysteine derivative
Modified residue1011Blocked carboxyl end (Arg)
Glycosylation411N-linked (GlcNAc...) Ref.1
Glycosylation841O-linked (Hex) Probable Ref.1
Disulfide bond61 ↔ 88 Probable

Sequences

Sequence LengthMass (Da)Tools
P00304 [UniParc].

Last modified October 1, 1993. Version 2.
Checksum: 3CBD6721B85C01DD

FASTA10111,375
        10         20         30         40         50         60 
GKVYLVGGPE LGGWKLQSDP RAYALWSARQ QFKTTDVLWF NFTTGEDSVA EVWREEAYHA 

        70         80         90        100 
CDIKDPIRLE PGGPDRFTLL TPGSHFICTK DQKFVACVPG R 

« Hide

References

[1]"Amino acid sequence of ragweed allergen Ra3."
Klapper D.G., Goodfriend L., Capra J.D.
Biochemistry 19:5729-5734(1980) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE, DISULFIDE BOND, GLYCOSYLATION AT ASN-41 AND SER-84.
Tissue: Pollen.

Cross-references

Sequence databases

PIRARRA3. A00313.

3D structure databases

ProteinModelPortalP00304.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome27. Amb a 3.
3068. Amb a 3.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.40.420. 1 hit.
InterProIPR008972. Cupredoxin.
IPR003245. Plcyanin-like.
[Graphical view]
PfamPF02298. Cu_bind_like. 1 hit.
[Graphical view]
ProDomPD003122. Plcyanin-like. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF49503. SSF49503. 1 hit.
PROSITEPS51485. PHYTOCYANIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMPAA3_AMBEL
AccessionPrimary (citable) accession number: P00304
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: October 1, 1993
Last modified: April 16, 2014
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries