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Protein

Cytochrome c3, 13 kDa

Gene
N/A
Organism
Desulfomicrobium norvegicum (strain DSM 1741 / NCIMB 8310) (Desulfovibrio baculatus (strain Norway 4)) (Desulfovibrio desulfuricans (strain Norway 4))
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi36Iron (heme 1 axial ligand)1
Metal bindingi39Iron (heme 3 axial ligand)1
Binding sitei44Heme 1 (covalent)1
Binding sitei47Heme 1 (covalent)1
Metal bindingi48Iron (heme 1 axial ligand)1
Metal bindingi49Iron (heme 2 axial ligand)1
Binding sitei61Heme 2 (covalent); atypical1
Binding sitei66Heme 2 (covalent); atypical1
Metal bindingi67Iron (heme 2 axial ligand)1
Metal bindingi89Iron (heme 4 axial ligand)1
Binding sitei92Heme 3 (covalent)1
Binding sitei95Heme 3 (covalent)1
Metal bindingi96Iron (heme 3 axial ligand)1
Binding sitei111Heme 4 (covalent)1
Binding sitei114Heme 4 (covalent)1
Metal bindingi115Iron (heme 4 axial ligand)1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Sulfate respiration, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c3, 13 kDa
OrganismiDesulfomicrobium norvegicum (strain DSM 1741 / NCIMB 8310) (Desulfovibrio baculatus (strain Norway 4)) (Desulfovibrio desulfuricans (strain Norway 4))
Taxonomic identifieri52561 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfomicrobiaceaeDesulfomicrobium

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001083581 – 118Cytochrome c3, 13 kDaAdd BLAST118

Post-translational modificationi

Binds 4 heme groups per subunit.

Proteomic databases

PRIDEiP00136.

Interactioni

Subunit structurei

Monomer.

Structurei

Secondary structure

1118
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi31 – 33Combined sources3
Helixi36 – 39Combined sources4
Helixi44 – 47Combined sources4
Turni49 – 56Combined sources8
Turni76 – 79Combined sources4
Helixi84 – 101Combined sources18
Helixi111 – 114Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CY3X-ray1.70A1-118[»]
ProteinModelPortaliP00136.
SMRiP00136.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP00136.

Family & Domainsi

Family and domain databases

InterProiIPR002322. Cyt_c_III.
IPR020942. Cyt_c_III_dom.
IPR011031. Multihaem_cyt.
[Graphical view]
PfamiPF02085. Cytochrom_CIII. 1 hit.
[Graphical view]
PRINTSiPR00609. CYTOCHROMEC3.
SUPFAMiSSF48695. SSF48695. 1 hit.

Sequencei

Sequence statusi: Complete.

P00136-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ADAPGDDYVI SAPEGMKAKP KGDKPGALQK TVPFPHTKHA TVECVQCHHT
60 70 80 90 100
LEADGGAVKK CTTSGCHDSL EFRDKANAKD IKLVENAFHT QCIDCHKALK
110
KDKKPTGPTA CGKCHTTN
Length:118
Mass (Da):12,622
Last modified:September 27, 2004 - v2
Checksum:iB9C3E8E14EC85728
GO

Sequence databases

PIRiA00129. CCDV3N.

Cross-referencesi

Sequence databases

PIRiA00129. CCDV3N.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CY3X-ray1.70A1-118[»]
ProteinModelPortaliP00136.
SMRiP00136.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP00136.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP00136.

Family and domain databases

InterProiIPR002322. Cyt_c_III.
IPR020942. Cyt_c_III_dom.
IPR011031. Multihaem_cyt.
[Graphical view]
PfamiPF02085. Cytochrom_CIII. 1 hit.
[Graphical view]
PRINTSiPR00609. CYTOCHROMEC3.
SUPFAMiSSF48695. SSF48695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYC31_DESNO
AccessioniPrimary (citable) accession number: P00136
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: September 27, 2004
Last modified: November 2, 2016
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The second heme binding site has an unusual CXXXXCH motif.

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.