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Protein

Cytochrome c3, 13 kDa

Gene
N/A
Organism
Desulfomicrobium norvegicum (strain DSM 1741 / NCIMB 8310) (Desulfovibrio baculatus (strain Norway 4)) (Desulfovibrio desulfuricans (strain Norway 4))
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi36 – 361Iron (heme 1 axial ligand)
Metal bindingi39 – 391Iron (heme 3 axial ligand)
Binding sitei44 – 441Heme 1 (covalent)
Binding sitei47 – 471Heme 1 (covalent)
Metal bindingi48 – 481Iron (heme 1 axial ligand)
Metal bindingi49 – 491Iron (heme 2 axial ligand)
Binding sitei61 – 611Heme 2 (covalent); atypical
Binding sitei66 – 661Heme 2 (covalent); atypical
Metal bindingi67 – 671Iron (heme 2 axial ligand)
Metal bindingi89 – 891Iron (heme 4 axial ligand)
Binding sitei92 – 921Heme 3 (covalent)
Binding sitei95 – 951Heme 3 (covalent)
Metal bindingi96 – 961Iron (heme 3 axial ligand)
Binding sitei111 – 1111Heme 4 (covalent)
Binding sitei114 – 1141Heme 4 (covalent)
Metal bindingi115 – 1151Iron (heme 4 axial ligand)

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Sulfate respiration, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c3, 13 kDa
OrganismiDesulfomicrobium norvegicum (strain DSM 1741 / NCIMB 8310) (Desulfovibrio baculatus (strain Norway 4)) (Desulfovibrio desulfuricans (strain Norway 4))
Taxonomic identifieri52561 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfomicrobiaceaeDesulfomicrobium

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 118118Cytochrome c3, 13 kDaPRO_0000108358Add
BLAST

Post-translational modificationi

Binds 4 heme groups per subunit.

Interactioni

Subunit structurei

Monomer.

Structurei

Secondary structure

1
118
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi31 – 333Combined sources
Helixi36 – 394Combined sources
Helixi44 – 474Combined sources
Turni49 – 568Combined sources
Turni76 – 794Combined sources
Helixi84 – 10118Combined sources
Helixi111 – 1144Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2CY3X-ray1.70A1-118[»]
ProteinModelPortaliP00136.
SMRiP00136. Positions 1-118.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP00136.

Family & Domainsi

Family and domain databases

InterProiIPR002322. Cyt_c_III.
IPR020942. Cyt_c_III_dom.
IPR011031. Multihaem_cyt.
[Graphical view]
PfamiPF02085. Cytochrom_CIII. 1 hit.
[Graphical view]
PRINTSiPR00609. CYTOCHROMEC3.
SUPFAMiSSF48695. SSF48695. 1 hit.

Sequencei

Sequence statusi: Complete.

P00136-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ADAPGDDYVI SAPEGMKAKP KGDKPGALQK TVPFPHTKHA TVECVQCHHT
60 70 80 90 100
LEADGGAVKK CTTSGCHDSL EFRDKANAKD IKLVENAFHT QCIDCHKALK
110
KDKKPTGPTA CGKCHTTN
Length:118
Mass (Da):12,622
Last modified:September 27, 2004 - v2
Checksum:iB9C3E8E14EC85728
GO

Sequence databases

PIRiA00129. CCDV3N.

Cross-referencesi

Sequence databases

PIRiA00129. CCDV3N.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2CY3X-ray1.70A1-118[»]
ProteinModelPortaliP00136.
SMRiP00136. Positions 1-118.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP00136.

Family and domain databases

InterProiIPR002322. Cyt_c_III.
IPR020942. Cyt_c_III_dom.
IPR011031. Multihaem_cyt.
[Graphical view]
PfamiPF02085. Cytochrom_CIII. 1 hit.
[Graphical view]
PRINTSiPR00609. CYTOCHROMEC3.
SUPFAMiSSF48695. SSF48695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYC31_DESNO
AccessioniPrimary (citable) accession number: P00136
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: September 27, 2004
Last modified: January 20, 2016
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The second heme binding site has an unusual CXXXXCH motif.

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.