Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c3

Gene
N/A
Organism
Desulfovibrio gigas
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.

Miscellaneous

The second and fourth heme binding sites have unusual CXXXXCH motifs.Combined sources1 Publication

Cofactori

heme1 PublicationNote: Binds 4 heme groups covalently per monomer.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi26Iron (heme 1 axial ligand); via tele nitrogenCombined sources1
Metal bindingi29Iron (heme 3 axial ligand); via tele nitrogenCombined sources1
Binding sitei34Heme 1 (covalent)Combined sources1
Binding sitei37Heme 1 (covalent)Combined sources1
Metal bindingi38Iron (heme 1 axial ligand); via tele nitrogenCombined sources1
Metal bindingi39Iron (heme 2 axial ligand); via tele nitrogenCombined sources1
Binding sitei49Heme 2 (covalent); atypicalCombined sources1
Binding sitei54Heme 2 (covalent); atypicalCombined sources1
Metal bindingi55Iron (heme 2 axial ligand); via tele nitrogenCombined sources1
Metal bindingi73Iron (heme 4 axial ligand); via tele nitrogenCombined sources1
Binding sitei83Heme 3 (covalent)Combined sources1
Binding sitei86Heme 3 (covalent)Combined sources1
Metal bindingi87Iron (heme 3 axial ligand); via tele nitrogenCombined sources1
Binding sitei104Heme 4 (covalent); atypicalCombined sources1
Binding sitei109Heme 4 (covalent); atypicalCombined sources1
Metal bindingi110Iron (heme 4 axial ligand); via tele nitrogenCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Sulfate respiration, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c3
OrganismiDesulfovibrio gigas
Taxonomic identifieri879 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001083601 – 112Cytochrome c3Add BLAST112

Structurei

Secondary structure

1112
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 10Combined sources3
Beta strandi22 – 24Combined sources3
Helixi27 – 29Combined sources3
Helixi34 – 36Combined sources3
Turni43 – 46Combined sources4
Beta strandi49 – 55Combined sources7
Beta strandi60 – 62Combined sources3
Helixi68 – 73Combined sources6
Helixi83 – 91Combined sources9
Helixi95 – 102Combined sources8
Beta strandi104 – 109Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QN0NMR-A1-112[»]
1QN1NMR-A1-112[»]
1WADX-ray1.80A1-112[»]
ProteinModelPortaliP00133.
SMRiP00133.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP00133.

Family & Domainsi

Family and domain databases

InterProiView protein in InterPro
IPR002322. Cyt_c_III.
IPR020942. Cyt_c_III_dom.
IPR011031. Multihaem_cyt.
PfamiView protein in Pfam
PF02085. Cytochrom_CIII. 1 hit.
PRINTSiPR00609. CYTOCHROMEC3.
SUPFAMiSSF48695. SSF48695. 1 hit.
PROSITEiView protein in PROSITE
PS51008. MULTIHEME_CYTC. 1 hit.

Sequencei

Sequence statusi: Complete.

P00133-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VDVPADGAKI DFIAGGEKNL TVVFNHSTHK DVKCDDCHHD PGDKQYAGCT
60 70 80 90 100
TDGCHNILDK ADKSVNSWYK VVHDAKGGAK PTCISCHKDK AGDDKELKKK
110
LTGCKGSACH PS
Length:112
Mass (Da):11,978
Last modified:July 15, 1999 - v2
Checksum:i61FF10231F4C0080
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti21Missing AA sequence (PubMed:11947254).Curated1

Sequence databases

PIRiA00126. CCDV3G.

Cross-referencesi

Sequence databases

PIRiA00126. CCDV3G.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QN0NMR-A1-112[»]
1QN1NMR-A1-112[»]
1WADX-ray1.80A1-112[»]
ProteinModelPortaliP00133.
SMRiP00133.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP00133.

Family and domain databases

InterProiView protein in InterPro
IPR002322. Cyt_c_III.
IPR020942. Cyt_c_III_dom.
IPR011031. Multihaem_cyt.
PfamiView protein in Pfam
PF02085. Cytochrom_CIII. 1 hit.
PRINTSiPR00609. CYTOCHROMEC3.
SUPFAMiSSF48695. SSF48695. 1 hit.
PROSITEiView protein in PROSITE
PS51008. MULTIHEME_CYTC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYC3_DESGI
AccessioniPrimary (citable) accession number: P00133
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 15, 1999
Last modified: November 2, 2016
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.