Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c3

Gene

DvMF_2499

Organism
Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi45Iron (heme 1 axial ligand)1
Metal bindingi48Iron (heme 3 axial ligand)1
Binding sitei53Heme 1 (covalent)1
Binding sitei56Heme 1 (covalent)1
Metal bindingi57Iron (heme 1 axial ligand)1
Metal bindingi58Iron (heme 2 axial ligand)1
Binding sitei69Heme 2 (covalent); atypical1
Binding sitei74Heme 2 (covalent); atypical1
Metal bindingi75Iron (heme 2 axial ligand)1
Metal bindingi93Iron (heme 4 axial ligand)1
Binding sitei102Heme 3 (covalent)1
Binding sitei105Heme 3 (covalent)1
Metal bindingi106Iron (heme 3 axial ligand)1
Binding sitei123Heme 4 (covalent); atypical1
Binding sitei128Heme 4 (covalent); atypical1
Metal bindingi129Iron (heme 4 axial ligand)1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Sulfate respiration, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciDVUL883:GCJ5-2546-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c3
Gene namesi
Ordered Locus Names:DvMF_2499
OrganismiDesulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Taxonomic identifieri883 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000001361 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 231 PublicationAdd BLAST23
ChainiPRO_000000650524 – 130Cytochrome c3Add BLAST107

Post-translational modificationi

Binds 4 heme groups per subunit.

Interactioni

Protein-protein interaction databases

STRINGi883.DvMF_2499.

Structurei

Secondary structure

1130
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi32 – 34Combined sources3
Beta strandi36 – 39Combined sources4
Beta strandi41 – 43Combined sources3
Helixi45 – 47Combined sources3
Turni48 – 50Combined sources3
Helixi53 – 55Combined sources3
Helixi88 – 93Combined sources6
Beta strandi95 – 99Combined sources5
Helixi102 – 110Combined sources9
Helixi114 – 121Combined sources8
Beta strandi123 – 128Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1IT1NMR-A24-130[»]
1J0OX-ray1.15A24-130[»]
1J0PX-ray0.91A23-130[»]
1WR5X-ray1.40A23-130[»]
2CDVX-ray1.80A24-130[»]
2EWIX-ray1.00A24-130[»]
2EWKX-ray1.00A24-130[»]
2EWUX-ray1.10A24-130[»]
2FFNX-ray1.80A24-130[»]
2YXCX-ray1.50A24-130[»]
2YYWX-ray1.33A24-130[»]
2YYXX-ray1.00A24-130[»]
2Z47X-ray1.60A/B24-130[»]
ProteinModelPortaliP00132.
SMRiP00132.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP00132.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4106BES. Bacteria.
ENOG410XXW1. LUCA.
HOGENOMiHOG000136348.
OMAiLMICLMV.
OrthoDBiPOG091H32QK.

Family and domain databases

InterProiIPR002322. Cyt_c_III.
IPR020942. Cyt_c_III_dom.
IPR011031. Multihaem_cyt.
[Graphical view]
PfamiPF02085. Cytochrom_CIII. 1 hit.
[Graphical view]
PRINTSiPR00609. CYTOCHROMEC3.
SUPFAMiSSF48695. SSF48695. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P00132-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKMFLTGVL ALAVAIAMPA LAAAPKAPAD GLKMDKTKQP VVFNHSTHKA
60 70 80 90 100
VKCGDCHHPV NGKEDYQKCA TAGCHDNMDK KDKSAKGYYH AMHDKGTKFK
110 120 130
SCVGCHLETA GADAAKKKEL TGCKGSKCHS
Length:130
Mass (Da):13,843
Last modified:July 15, 1998 - v2
Checksum:iCCBBA60351B9EF8E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti65D → N AA sequence (PubMed:6249799).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D31702 Genomic DNA. Translation: BAA06511.1.
CP001197 Genomic DNA. Translation: ACL09439.1.
PIRiS33874. CCDV3M.
RefSeqiWP_015946129.1. NC_011769.1.

Genome annotation databases

EnsemblBacteriaiACL09439; ACL09439; DvMF_2499.
KEGGidvm:DvMF_2499.
PATRICi21775419. VBIDesVul86729_2712.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D31702 Genomic DNA. Translation: BAA06511.1.
CP001197 Genomic DNA. Translation: ACL09439.1.
PIRiS33874. CCDV3M.
RefSeqiWP_015946129.1. NC_011769.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1IT1NMR-A24-130[»]
1J0OX-ray1.15A24-130[»]
1J0PX-ray0.91A23-130[»]
1WR5X-ray1.40A23-130[»]
2CDVX-ray1.80A24-130[»]
2EWIX-ray1.00A24-130[»]
2EWKX-ray1.00A24-130[»]
2EWUX-ray1.10A24-130[»]
2FFNX-ray1.80A24-130[»]
2YXCX-ray1.50A24-130[»]
2YYWX-ray1.33A24-130[»]
2YYXX-ray1.00A24-130[»]
2Z47X-ray1.60A/B24-130[»]
ProteinModelPortaliP00132.
SMRiP00132.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi883.DvMF_2499.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL09439; ACL09439; DvMF_2499.
KEGGidvm:DvMF_2499.
PATRICi21775419. VBIDesVul86729_2712.

Phylogenomic databases

eggNOGiENOG4106BES. Bacteria.
ENOG410XXW1. LUCA.
HOGENOMiHOG000136348.
OMAiLMICLMV.
OrthoDBiPOG091H32QK.

Enzyme and pathway databases

BioCyciDVUL883:GCJ5-2546-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP00132.

Family and domain databases

InterProiIPR002322. Cyt_c_III.
IPR020942. Cyt_c_III_dom.
IPR011031. Multihaem_cyt.
[Graphical view]
PfamiPF02085. Cytochrom_CIII. 1 hit.
[Graphical view]
PRINTSiPR00609. CYTOCHROMEC3.
SUPFAMiSSF48695. SSF48695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYC3_DESVM
AccessioniPrimary (citable) accession number: P00132
Secondary accession number(s): B8DMZ9, Q46607
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 15, 1998
Last modified: November 2, 2016
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The second and fourth heme binding sites have unusual CXXXXCH motifs.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.