Reviewed,
UniProtKB/Swiss-Prot P00096 (CY550_PARDE)
Last modified
January 19, 2010.
Version 86.
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Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Cytochrome c-550 Alternative name(s): Cytochrome c550 Cytochrome C2 | ||
| Gene names |
| ||
| Organism | Paracoccus denitrificans | ||
| Taxonomic identifier | 266 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus |
Protein attributes
| Sequence length | 155 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Post-translational modification | Binds 1 heme group per subunit. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Electron transport Transport |
| Domain | Signal |
| Ligand | Heme Iron Metal-binding |
| PTM | Pyrrolidone carboxylic acid |
| Technical term | 3D-structure Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transportInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | electron carrier activity Inferred from electronic annotation. Source: InterPro heme bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||||||||||||||||
Molecule processing | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 20 | 20 | Ref.4 | ||||||||||||||||||||||
| Chain | 21 – 149 | 129 | Cytochrome c-550 | PRO_0000006523 | |||||||||||||||||||||
| Propeptide | 150 – 155 | 6 | PRO_0000006524 | ||||||||||||||||||||||
Sites | |||||||||||||||||||||||||
| Metal binding | 39 | 1 | Iron (heme axial ligand) Ref.5 | ||||||||||||||||||||||
| Metal binding | 120 | 1 | Iron (heme axial ligand) Ref.5 | ||||||||||||||||||||||
| Binding site | 35 | 1 | Heme (covalent) Ref.5 | ||||||||||||||||||||||
| Binding site | 38 | 1 | Heme (covalent) Ref.5 | ||||||||||||||||||||||
Amino acid modifications | |||||||||||||||||||||||||
| Modified residue | 21 | 1 | Pyrrolidone carboxylic acid Ref.4 | ||||||||||||||||||||||
Natural variations | |||||||||||||||||||||||||
| Natural variant | 149 | 1 | Missing in 50% of the molecules. | ||||||||||||||||||||||
Secondary structure | |||||||||||||||||||||||||
Helix Strand Turn | |||||||||||||||||||||||||
| Helix | 25 – 31 | 7 | |||||||||||||||||||||||
| Helix | 32 – 34 | 3 | |||||||||||||||||||||||
| Turn | 35 – 38 | 4 | |||||||||||||||||||||||
| Beta strand | 48 – 50 | 3 | |||||||||||||||||||||||
| Beta strand | 54 – 56 | 3 | |||||||||||||||||||||||
| Helix | 77 – 85 | 9 | |||||||||||||||||||||||
| Helix | 93 – 101 | 9 | |||||||||||||||||||||||
| Helix | 103 – 111 | 9 | |||||||||||||||||||||||
| Helix | 128 – 137 | 10 | |||||||||||||||||||||||
Sequences
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References
| [1] | "Are there isoenzymes of cytochrome c oxidase in Paracoccus denitrificans?" Raitio M., Pispa J.M., Metso T., Saraste M. FEBS Lett. 261:431-435(1990) [PubMed: 2155830] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Pd 1222. |
| [2] | "Mutagenesis of the gene encoding cytochrome c550 of Paracoccus denitrificans and analysis of the resultant physiological effects." van Spanning R.J.M., Wansell C., Harms N., Oltmann L.F., Stouthamer A.H. J. Bacteriol. 172:986-996(1990) [PubMed: 2153663] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Pd 1222. |
| [3] | Erratum van Spanning R.J.M., Wansell C., Harms N., Oltmann L.F., Stouthamer A.H. J. Bacteriol. 172:3534-3534(1990) [PubMed: 2160949] [Abstract] |
| [4] | "A reassessment of the structure of Paracoccus cytochrome c-550." Ambler R.P., Meyer T.E., Kamen M.D., Schichman S.A., Sawyer L. J. Mol. Biol. 147:351-356(1981) [PubMed: 6270339] [Abstract] Cited for: PROTEIN SEQUENCE OF 21-149. Strain: ATCC 13543 / NRRL B-3784. |
| [5] | "The structure of Paracoccus denitrificans cytochrome c550." Timkovich R., Dickerson R.E. J. Biol. Chem. 251:4033-4046(1976) [PubMed: 180013] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.45 ANGSTROMS). |
| [6] | "X-ray structure of the cytochrome c2 isolated from Paracoccus denitrificans refined to 1.7-A resolution." Benning M.M., Meyer T.E., Holden H.M. Arch. Biochem. Biophys. 310:460-466(1994) [PubMed: 8179333] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS). |
Cross-references
Sequence databases | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EMBL GenBank DDBJ | Y07533 Genomic DNA. Translation: CAA68820.1. M27304 Genomic DNA. Translation: AAA88364.1. | ||||||||||||||||||
| PIR | CCPC50. S08269. | ||||||||||||||||||
| RefSeq | YP_915726.1. | ||||||||||||||||||
3D structure databases | |||||||||||||||||||
| PDBe RCSB PDB PDBj |
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| ModBase | Search... | ||||||||||||||||||
Protein family/group databases | |||||||||||||||||||
| TCDB | 3.D.4.6.1. proton-translocating cytochrome oxidase (COX) superfamily. | ||||||||||||||||||
Genome annotation databases | |||||||||||||||||||
| GeneID | 4581059. | ||||||||||||||||||
Family and domain databases | |||||||||||||||||||
| InterPro | IPR002327. Cyt_c_1A/1B. IPR009056. Cyt_c_monohaem. [Graphical view] | ||||||||||||||||||
| Gene3D | G3DSA:1.10.760.10. Cytochrome_c_R. 1 hit. | ||||||||||||||||||
| PANTHER | PTHR11961. Cyt_CIAB. 1 hit. | ||||||||||||||||||
| PROSITE | PS51007. CYTC. 1 hit. [Graphical view] | ||||||||||||||||||
| ProtoNet | Search... | ||||||||||||||||||
Entry information
| Entry name | CY550_PARDE | ||||||||
| Accession | Primary (citable) accession number: P00096 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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