Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c2

Gene

cycA

Organism
Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei34 – 341Heme (covalent)
Binding sitei37 – 371Heme (covalent)
Metal bindingi38 – 381Iron (heme axial ligand)
Metal bindingi117 – 1171Iron (heme axial ligand)

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Photosynthesis, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciRCAP272942:GJIY-1261-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c2
Gene namesi
Name:cycA
Ordered Locus Names:RCAP_rcc01240
OrganismiRhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Taxonomic identifieri272942 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000002361 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 21211 PublicationAdd
BLAST
Chaini22 – 137116Cytochrome c21 PublicationPRO_0000006497Add
BLAST

Post-translational modificationi

Binds 1 heme group per subunit.

Interactioni

Protein-protein interaction databases

IntActiP00094. 1 interaction.
STRINGi272942.RCAP_rcc01240.

Structurei

Secondary structure

1
137
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi24 – 307Combined sources
Helixi31 – 333Combined sources
Turni34 – 374Combined sources
Beta strandi47 – 493Combined sources
Beta strandi53 – 553Combined sources
Helixi76 – 838Combined sources
Helixi90 – 989Combined sources
Helixi100 – 1089Combined sources
Beta strandi122 – 1243Combined sources
Helixi125 – 13410Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1C2NNMR-A1-137[»]
1C2RX-ray2.50A/B22-137[»]
1VYDX-ray2.30A/B22-137[»]
ProteinModelPortaliP00094.
SMRiP00094. Positions 22-137.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP00094.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG3474. LUCA.
HOGENOMiHOG000009762.
KOiK08738.
OMAiNKCKSCH.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
[Graphical view]
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P00094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKISLTAATV AALVLAAPAF AGDAAKGEKE FNKCKTCHSI IAPDGTEIVK
60 70 80 90 100
GAKTGPNLYG VVGRTAGTYP EFKYKDSIVA LGASGFAWTE EDIATYVKDP
110 120 130
GAFLKEKLDD KKAKTGMAFK LAKGGEDVAA YLASVVK
Length:137
Mass (Da):14,279
Last modified:April 1, 1988 - v1
Checksum:i394E29348E4537CD
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti108 – 1081L → T in strain: 2.3.1.
Natural varianti115 – 1151T → S in strain: 2.3.1.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M12776 Genomic DNA. Translation: AAA26102.1.
CP001312 Genomic DNA. Translation: ADE84997.1.
PIRiA25452. CCRF2C.

Genome annotation databases

EnsemblBacteriaiADE84997; ADE84997; RCAP_rcc01240.
KEGGircp:RCAP_rcc01240.
PATRICi35502592. VBIRhoCap134200_1264.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M12776 Genomic DNA. Translation: AAA26102.1.
CP001312 Genomic DNA. Translation: ADE84997.1.
PIRiA25452. CCRF2C.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1C2NNMR-A1-137[»]
1C2RX-ray2.50A/B22-137[»]
1VYDX-ray2.30A/B22-137[»]
ProteinModelPortaliP00094.
SMRiP00094. Positions 22-137.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP00094. 1 interaction.
STRINGi272942.RCAP_rcc01240.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADE84997; ADE84997; RCAP_rcc01240.
KEGGircp:RCAP_rcc01240.
PATRICi35502592. VBIRhoCap134200_1264.

Phylogenomic databases

eggNOGiCOG3474. LUCA.
HOGENOMiHOG000009762.
KOiK08738.
OMAiNKCKSCH.

Enzyme and pathway databases

BioCyciRCAP272942:GJIY-1261-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP00094.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
[Graphical view]
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cytochrome c2 is not essential for photosynthetic growth of Rhodopseudomonas capsulata."
    Daldal F., Cheng S., Applebaum J., Davidson E., Prince R.C.
    Proc. Natl. Acad. Sci. U.S.A. 83:2012-2016(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC BAA-309 / NBRC 16581 / SB1003.
  2. "Complete genome sequence of the photosynthetic purple nonsulfur bacterium Rhodobacter capsulatus SB 1003."
    Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V., Haselkorn R.
    J. Bacteriol. 192:3545-3546(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-309 / NBRC 16581 / SB1003.
  3. "Cytochrome c2 sequence variation among the recognised species of purple nonsulphur photosynthetic bacteria."
    Ambler R.P., Daniel M., Hermoso J., Meyer T.E., Bartsch R.G., Kamen M.D.
    Nature 278:659-660(1979) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 22-137.
    Strain: ATCC 11166 / 2.3.1 and ATCC 23782 / St Louis.
  4. "Molecular structure of cytochrome c2 isolated from Rhodobacter capsulatus determined at 2.5-A resolution."
    Benning M.M., Wesenberg G., Caffrey M.S., Bartsch R.G., Meyer T.E., Cusanovich M.A., Rayment I., Holden H.M.
    J. Mol. Biol. 220:673-685(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS).
  5. "Assignment of the 1H and 15N NMR spectra of Rhodobacter capsulatus ferrocytochrome c2."
    Gooley P.R., Caffrey M.S., Cusanovich M.A., McKenzie N.E.
    Biochemistry 29:2278-2290(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR.
  6. "Solution structure, rotational diffusion anisotropy and local backbone dynamics of Rhodobacter capsulatus cytochrome c2."
    Cordier F., Caffrey M., Brutscher B., Cusanovich M.A., Marion D., Blackledge M.
    J. Mol. Biol. 281:341-361(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR.
    Strain: ATCC BAA-309 / NBRC 16581 / SB1003.

Entry informationi

Entry nameiCYC2_RHOCB
AccessioniPrimary (citable) accession number: P00094
Secondary accession number(s): D5ASA6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: April 1, 1988
Last modified: November 11, 2015
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.