P00082 (CYC2_RHOVT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c2

Gene names

Ordered Locus Names:

Rvan_1007

Organism

Rhodomicrobium vannielii (strain ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299) [Complete proteome] [HAMAP]

Taxonomic identifier

648757 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Hyphomicrobiaceae › Rhodomicrobium › Rhodomicrobium vannielii

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
Post-translational modification	Binds 1 heme group per subunit.
Sequence similarities	Belongs to the cytochrome c family. Contains 1 cytochrome c domain.

Ontologies

Keywords
Biological process	Electron transport Photosynthesis Transport
Domain	Signal
Ligand	Heme Iron Metal-binding
Technical term	Complete proteome Direct protein sequencing
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW photosynthesis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Ref.2
	Chain	22 – 125	104	Cytochrome c2		PRO_0000108348
Regions
	Domain	23 – 123	101	Cytochrome c
Sites
	Metal binding	39	1	Iron (heme axial ligand)
	Metal binding	101	1	Iron (heme axial ligand)
	Binding site	35	1	Heme (covalent)
	Binding site	38	1	Heme (covalent)
Experimental info
	Sequence conflict	47	1	P → N AA sequence Ref.2
	Sequence conflict	52	1	V → E AA sequence Ref.2
	Sequence conflict	55 – 59	5	NVVGS → DVFGQ AA sequence Ref.2
	Sequence conflict	63	1	S → A AA sequence Ref.2
	Sequence conflict	118 – 125	8	FLATQHGQ → YLKQLSGK AA sequence Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P00082 [UniParc]. Last modified February 8, 2011. Version 2. Checksum: 9E8949E84DE2423D	FASTA	125	13,187
	10 20 30 40 50 60 MKAIKIAMVG AALVWSASAY AAGDPVKGEQ VFKQCKICHQ VGPTAKPGVG PVQNNVVGSK 70 80 90 100 110 120 AGSRPGFNYS DAMKNSGLTW DEATLDKYLE NPKAVVPGTK MVFVGLKNPQ DRADVIAFLA TQHGQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequences of eight morphologically diverse alphaproteobacteria." US DOE Joint Genome Institute Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V. J. Bacteriol. 193:4567-4568(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299.
[2]	"Primary structure determination of two cytochromes c2: close similarity to functionally unrelated mitochondrial cytochrome C." Ambler R.P., Meyer T.E., Kamen M.D. Proc. Natl. Acad. Sci. U.S.A. 73:472-475(1976) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 22-125. Strain: ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002292 Genomic DNA. Translation: ADP70281.1.
PIR	CCRD2. A00074.
RefSeq	YP_004011380.1. NC_014664.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADP70281; ADP70281; Rvan_1007.
GeneID	9931784.
KEGG	rva:Rvan_1007.
PATRIC	42669148. VBIRhoVan113057_1067.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000009762.
KO	K08738.
Enzyme and pathway databases
BioCyc	RVAN648757:GHZT-1020-MONOMER.
Family and domain databases
InterPro	IPR002327. Cyt_c_1A/1B. IPR009056. Cyt_c_dom. IPR003088. Cyt_c_I. [Graphical view]
PANTHER	PTHR11961. PTHR11961. 1 hit.
Pfam	PF00034. Cytochrom_C. 1 hit. [Graphical view]
PRINTS	PR00604. CYTCHRMECIAB.
SUPFAM	SSF46626. Cytochrome_c. 1 hit.
PROSITE	PS51007. CYTC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYC2_RHOVT

Accession

Primary (citable) accession number: P00082
Secondary accession number(s): E3I2Y7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	February 8, 2011
Last modified:	May 1, 2013
This is version 81 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program