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Protein

Cytochrome c2

Gene

Rvan_1007

Organism
Rhodomicrobium vannielii (strain ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei35 – 351Heme (covalent)
Binding sitei38 – 381Heme (covalent)
Metal bindingi39 – 391Iron (heme axial ligand)
Metal bindingi101 – 1011Iron (heme axial ligand)

GO - Molecular functioni

  1. electron carrier activity Source: InterPro
  2. heme binding Source: InterPro
  3. iron ion binding Source: InterPro

GO - Biological processi

  1. oxidation-reduction process Source: UniProtKB-KW
  2. photosynthesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Photosynthesis, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciRVAN648757:GHZT-1020-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c2
Gene namesi
Ordered Locus Names:Rvan_1007
OrganismiRhodomicrobium vannielii (strain ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299)
Taxonomic identifieri648757 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesHyphomicrobiaceaeRhodomicrobium
ProteomesiUP000001399 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 21211 PublicationAdd
BLAST
Chaini22 – 125104Cytochrome c2PRO_0000108348Add
BLAST

Post-translational modificationi

Binds 1 heme group per subunit.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 123101Cytochrome cPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cytochrome c family.Curated
Contains 1 cytochrome c domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000009762.
KOiK08738.
OMAiTWLKEST.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
[Graphical view]
PANTHERiPTHR11961. PTHR11961. 1 hit.
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00604. CYTCHRMECIAB.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P00082-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAIKIAMVG AALVWSASAY AAGDPVKGEQ VFKQCKICHQ VGPTAKPGVG
60 70 80 90 100
PVQNNVVGSK AGSRPGFNYS DAMKNSGLTW DEATLDKYLE NPKAVVPGTK
110 120
MVFVGLKNPQ DRADVIAFLA TQHGQ
Length:125
Mass (Da):13,187
Last modified:February 7, 2011 - v2
Checksum:i9E8949E84DE2423D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti47 – 471P → N AA sequence (PubMed:174109).Curated
Sequence conflicti52 – 521V → E AA sequence (PubMed:174109).Curated
Sequence conflicti55 – 595NVVGS → DVFGQ AA sequence (PubMed:174109).Curated
Sequence conflicti63 – 631S → A AA sequence (PubMed:174109).Curated
Sequence conflicti118 – 1258FLATQHGQ → YLKQLSGK AA sequence (PubMed:174109).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002292 Genomic DNA. Translation: ADP70281.1.
PIRiA00074. CCRD2.
RefSeqiYP_004011380.1. NC_014664.1.

Genome annotation databases

EnsemblBacteriaiADP70281; ADP70281; Rvan_1007.
KEGGirva:Rvan_1007.
PATRICi42669148. VBIRhoVan113057_1067.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002292 Genomic DNA. Translation: ADP70281.1.
PIRiA00074. CCRD2.
RefSeqiYP_004011380.1. NC_014664.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADP70281; ADP70281; Rvan_1007.
KEGGirva:Rvan_1007.
PATRICi42669148. VBIRhoVan113057_1067.

Phylogenomic databases

HOGENOMiHOG000009762.
KOiK08738.
OMAiTWLKEST.

Enzyme and pathway databases

BioCyciRVAN648757:GHZT-1020-MONOMER.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
[Graphical view]
PANTHERiPTHR11961. PTHR11961. 1 hit.
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00604. CYTCHRMECIAB.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299.
  2. "Primary structure determination of two cytochromes c2: close similarity to functionally unrelated mitochondrial cytochrome C."
    Ambler R.P., Meyer T.E., Kamen M.D.
    Proc. Natl. Acad. Sci. U.S.A. 73:472-475(1975) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 22-125.
    Strain: ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299.

Entry informationi

Entry nameiCYC2_RHOVT
AccessioniPrimary (citable) accession number: P00082
Secondary accession number(s): E3I2Y7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 20, 1986
Last sequence update: February 7, 2011
Last modified: March 31, 2015
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.