P00071 (CYC_PASSA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Cytochrome c
Organism	Pastinaca sativa (Parsnip)
Taxonomic identifier	4041 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Apiales › Apiaceae › Apiaceae incertae sedis › Tordylieae › Pastinaca

Protein attributes

Sequence length	111 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Subcellular location	Mitochondrion matrix.
Post-translational modification	Binds 1 heme group per subunit.
Sequence similarities	Belongs to the cytochrome c family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Mitochondrion
Ligand	Heme Iron Metal-binding
PTM	Acetylation Methylation
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 111	111	Cytochrome c		PRO_0000108304
Sites
	Metal binding	26	1	Iron (heme axial ligand)
	Metal binding	88	1	Iron (heme axial ligand)
	Binding site	22	1	Heme (covalent)
	Binding site	25	1	Heme (covalent)
Amino acid modifications
	Modified residue	1	1	N-acetylalanine Ref.1
	Modified residue	80	1	N6,N6,N6-trimethyllysine Ref.1
	Modified residue	94	1	N6,N6,N6-trimethyllysine Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P00071 [UniParc]. Last modified July 21, 1986. Version 1. Checksum: 5DFC4CF714C2F6E0	FASTA	111	11,929
	10 20 30 40 50 60 ASFAEAPPGD KDVGGKIFKT KCAZCHTVZL GAGHKQGPNL NGLFGRQSGT TAGYSYSAAN 70 80 90 100 110 KNKAVLWABB TLYDYLLNPK KYIPGTKMVF PGLKKPQDRA DLIAYLKHAT A

References

[1]	"The amino acid sequences of cytochrome c from four plant sources." Brown R.H., Boulter D. Biochem. J. 137:93-100(1974) [PubMed: 4362498] [Abstract] Cited for: PROTEIN SEQUENCE.
+	Additional computationally mapped references.

Web resources

Protein Spotlight

Life shuttle - Issue 76 of November 2006

Cross-references

Sequence databases
PIR	CCPZ. A00063.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR002327. Cyt_c_1A/1B. IPR009056. Cyt_c_dom. IPR003088. Cyt_c_I. [Graphical view]
Gene3D	G3DSA:1.10.760.10. Cytochrome_c_R. 1 hit.
PANTHER	PTHR11961. Cyt_CIAB. 1 hit.
Pfam	PF00034. Cytochrom_C. 1 hit. [Graphical view]
PRINTS	PR00604. CYTCHRMECIAB.
SUPFAM	SSF46626. Cytochrome_c. 1 hit.
PROSITE	PS51007. CYTC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYC_PASSA

Accession

Primary (citable) accession number: P00071

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	July 21, 1986
Last modified:	September 21, 2011
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program