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Protein

Cytochrome c

Gene
N/A
Organism
Ustilago sphaerogena (Smut fungus)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei18Heme (covalent)PROSITE-ProRule annotation1 Publication1
Binding sitei21Heme (covalent)PROSITE-ProRule annotation1 Publication1
Metal bindingi22Iron (heme axial ligand)1
Metal bindingi84Iron (heme axial ligand)1

GO - Molecular functioni

Keywordsi

Biological processElectron transport, Respiratory chain, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c
OrganismiUstilago sphaerogena (Smut fungus)
Taxonomic identifieri5271 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaUstilaginomycetesUstilaginalesUstilaginaceaeUstilago

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001083351 – 107Cytochrome cAdd BLAST107

Post-translational modificationi

Binds 1 heme group per subunit.

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiP00049

Structurei

3D structure databases

ProteinModelPortaliP00049
SMRiP00049
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Family and domain databases

Gene3Di1.10.760.10, 1 hit
InterProiView protein in InterPro
IPR009056 Cyt_c-like_dom
IPR036909 Cyt_c-like_dom_sf
IPR002327 Cyt_c_1A/1B
PANTHERiPTHR11961 PTHR11961, 1 hit
PfamiView protein in Pfam
PF00034 Cytochrom_C, 1 hit
PRINTSiPR00604 CYTCHRMECIAB
SUPFAMiSSF46626 SSF46626, 1 hit
PROSITEiView protein in PROSITE
PS51007 CYTC, 1 hit

Sequencei

Sequence statusi: Complete.

P00049-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GFEDGDAKKG ARIFKTRCAQ CHTLGAGEPN KVGPNLHGLF GRKSGTVEGF
60 70 80 90 100
SYTDANKKAG QVWEEETFLE YLENPKKYIP GTKMAFGGLK KEKDRNDLVT

YLREETK
Length:107
Mass (Da):11,945
Last modified:July 21, 1986 - v1
Checksum:i9D14B56FEC182D0A
GO

Sequence databases

PIRiA00042 CCUS

Similar proteinsi

Entry informationi

Entry nameiCYC_USTSP
AccessioniPrimary (citable) accession number: P00049
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing
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Main funding by: National Institutes of Health