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P00042 (CYC_HANAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c
OrganismHansenula anomala (Yeast) (Candida pelliculosa)
Taxonomic identifier4927 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeWickerhamomyces

Protein attributes

Sequence length109 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.

Subcellular location

Mitochondrion intermembrane space. Note: Loosely associated with the inner membrane.

Post-translational modification

Binds 1 heme group per subunit.

Sequence similarities

Belongs to the cytochrome c family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 109109Cytochrome c
PRO_0000108325

Sites

Metal binding241Iron (heme axial ligand)
Metal binding861Iron (heme axial ligand)
Binding site201Heme (covalent) Ref.1
Binding site231Heme (covalent) Ref.1

Amino acid modifications

Modified residue61N6-acetyllysine
Modified residue611N6,N6-dimethyllysine; alternate Ref.1
Modified residue611N6-methyllysine; alternate
Modified residue781N6,N6,N6-trimethyllysine Ref.1
Modified residue791N6,N6,N6-trimethyllysine Ref.1

Sequences

Sequence LengthMass (Da)Tools
P00042 [UniParc].

Last modified July 21, 1986. Version 1.
Checksum: 49CDCB05D9EDBCBB

FASTA10912,064
        10         20         30         40         50         60 
PAPFKKGSEK KGATLFKTRC LQCHTVEKGG PHKVGPNLHG IFGRQSGKAE GYSYTDANIK 

        70         80         90        100 
KAVEWSEQTM SDYLENPKKY IPGTKMAFGG LKKEKDRNDL VTYLANATK 

« Hide

References

[1]"Amino-acid sequence of the cytochrome c from the yeast Hansenula anomala. Identification of three methylated positions."
Becam A.-M., Lederer F.
Eur. J. Biochem. 118:295-302(1981) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.

Web resources

Protein Spotlight

Life shuttle - Issue 76 of November 2006

Cross-references

Sequence databases

PIRCCHQ. A00035.

3D structure databases

ProteinModelPortalP00042.
SMRP00042. Positions 2-109.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.760.10. 1 hit.
InterProIPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
IPR003088. Cyt_c_dom.
[Graphical view]
PANTHERPTHR11961. PTHR11961. 1 hit.
PfamPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSPR00604. CYTCHRMECIAB.
SUPFAMSSF46626. SSF46626. 1 hit.
PROSITEPS51007. CYTC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCYC_HANAN
AccessionPrimary (citable) accession number: P00042
Entry history
Integrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: April 16, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries