Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O99822

- COX3_RHISA

UniProt

O99822 - COX3_RHISA

Protein

Cytochrome c oxidase subunit 3

Gene

COIII

Organism
Rhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Subunits I, II and III form the functional core of the enzyme complex.

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide III
    Gene namesi
    Name:COIII
    Encoded oniMitochondrion
    OrganismiRhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus)
    Taxonomic identifieri34632 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeRhipicephalinaeRhipicephalusRhipicephalus

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 257257Cytochrome c oxidase subunit 3PRO_0000183845Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO99822.
    SMRiO99822. Positions 3-257.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei13 – 3321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei36 – 5621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei80 – 10021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei154 – 17421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei195 – 21521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei237 – 25721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O99822-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMFHPFHLVE KSPWPITSSI SALSLTLGFV SYFQNLSMYL ILLAVLMITI    50
    SSFQWWRDIS REGSFQGFHT HWVLNGLKMG MILFILSEVF FFVSFFWAFF 100
    HSSLSPNIEI GSQWPPKGIY PFNPFEIPLL NSTILISSGI TVTWSHHAIM 150
    NKNYISALNS LLITILLGVA FTMFQGFEYF QAQFKISDGI FGSTFFMTTG 200
    FHGLHVLIGS IFLLVSYFRI KNQLISSDHF FGFEASAWYW HFVDVVWLFL 250
    FTFMYWW 257
    Length:257
    Mass (Da):29,936
    Last modified:May 1, 1999 - v1
    Checksum:iB9741FD84E0504EC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF081829 Genomic DNA. Translation: AAD05522.1.
    PIRiT11158.
    RefSeqiNP_008515.1. NC_002074.1.

    Genome annotation databases

    GeneIDi808371.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF081829 Genomic DNA. Translation: AAD05522.1 .
    PIRi T11158.
    RefSeqi NP_008515.1. NC_002074.1.

    3D structure databases

    ProteinModelPortali O99822.
    SMRi O99822. Positions 3-257.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 808371.

    Organism-specific databases

    CTDi 4514.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Mitochondrial gene order is not conserved in arthropods: prostriate and metastriate tick mitochondrial genomes."
      Black W.C. IV, Roehrdanz R.L.
      Mol. Biol. Evol. 15:1772-1785(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiCOX3_RHISA
    AccessioniPrimary (citable) accession number: O99822
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3