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O99822 (COX3_RHISA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismRhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus)
Taxonomic identifier34632 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeRhipicephalinaeRhipicephalusRhipicephalus

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257Cytochrome c oxidase subunit 3
PRO_0000183845

Regions

Transmembrane13 – 3321Helical; Potential
Transmembrane36 – 5621Helical; Potential
Transmembrane80 – 10021Helical; Potential
Transmembrane154 – 17421Helical; Potential
Transmembrane195 – 21521Helical; Potential
Transmembrane237 – 25721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O99822 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: B9741FD84E0504EC

FASTA25729,936
        10         20         30         40         50         60 
MMFHPFHLVE KSPWPITSSI SALSLTLGFV SYFQNLSMYL ILLAVLMITI SSFQWWRDIS 

        70         80         90        100        110        120 
REGSFQGFHT HWVLNGLKMG MILFILSEVF FFVSFFWAFF HSSLSPNIEI GSQWPPKGIY 

       130        140        150        160        170        180 
PFNPFEIPLL NSTILISSGI TVTWSHHAIM NKNYISALNS LLITILLGVA FTMFQGFEYF 

       190        200        210        220        230        240 
QAQFKISDGI FGSTFFMTTG FHGLHVLIGS IFLLVSYFRI KNQLISSDHF FGFEASAWYW 

       250 
HFVDVVWLFL FTFMYWW 

« Hide

References

[1]"Mitochondrial gene order is not conserved in arthropods: prostriate and metastriate tick mitochondrial genomes."
Black W.C. IV, Roehrdanz R.L.
Mol. Biol. Evol. 15:1772-1785(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF081829 Genomic DNA. Translation: AAD05522.1.
PIRT11158.
RefSeqNP_008515.1. NC_002074.1.

3D structure databases

ProteinModelPortalO99822.
SMRO99822. Positions 3-257.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID808371.

Organism-specific databases

CTD4514.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_RHISA
AccessionPrimary (citable) accession number: O99822
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: July 9, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families