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Protein
Submitted name:

Sodium-calcium exchanger isoform NCX1.3

Gene

NCX1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium-calcium exchanger isoform NCX1.3Imported
Gene namesi
Name:NCX1Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei75 – 93HelicalSequence analysisAdd BLAST19
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Transmembranei163 – 188HelicalSequence analysisAdd BLAST26
Transmembranei200 – 223HelicalSequence analysisAdd BLAST24
Transmembranei229 – 249HelicalSequence analysisAdd BLAST21
Transmembranei759 – 783HelicalSequence analysisAdd BLAST25
Transmembranei836 – 856HelicalSequence analysisAdd BLAST21
Transmembranei868 – 888HelicalSequence analysisAdd BLAST21
Transmembranei904 – 922HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_500416074733 – 934Sequence analysisAdd BLAST902

Structurei

3D structure databases

ProteinModelPortaliO97801
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini302 – 365JInterPro annotationAdd BLAST64

Sequence similaritiesi

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. [View classification]SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOGENOMiHOG000266971
HOVERGENiHBG006441
KOiK05849

Family and domain databases

Gene3Di2.60.40.2030, 2 hits
InterProiView protein in InterPro
IPR038081 CalX-like_sf
IPR003644 Calx_beta
IPR001623 DnaJ_domain
IPR004836 Na_Ca_Ex
IPR032452 Na_Ca_Ex_C-exten
IPR002987 NaCa_exhngr1
IPR004837 NaCa_Exmemb
PfamiView protein in Pfam
PF03160 Calx-beta, 2 hits
PF01699 Na_Ca_ex, 2 hits
PF16494 Na_Ca_ex_C, 1 hit
PRINTSiPR01259 NACAEXCHNGR
PR01260 NACAEXCHNGR1
SMARTiView protein in SMART
SM00237 Calx_beta, 2 hits
SUPFAMiSSF141072 SSF141072, 2 hits
TIGRFAMsiTIGR00845 caca, 1 hit
PROSITEiView protein in PROSITE
PS50076 DNAJ_2, 1 hit

Sequencei

Sequence statusi: Complete.

O97801-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRLSLSPTF SMGFHLLVIV ALLFSHVDYV IAETEMEGEG NETGECTGSY
60 70 80 90 100
YCKKGVILPI WEPQDPSFGD KIARATVYFV AMVYMFLGVS IIADRFMSSI
110 120 130 140 150
EVITSQEKEI TIKKPNGETT KTTVRIWNET VSNLTLMALG SSAPEILLSV
160 170 180 190 200
IEVCGHNFTA GDLGPSTIVG SAAFNMFIII ALCVYVVPDG ETRKIKHLRV
210 220 230 240 250
FFVTAAWSIF AYTWLYIILS VISPGVVEVW EGLLTFFFFP ICVVFAWVAD
260 270 280 290 300
RRLLFYKYVY KRYRAGKQRG MIIEHEGDRP SSKTEIEMDG KVVNSHVENF
310 320 330 340 350
LDGALVLEVD ERDQDDEEAR REMARILKEL KQKHPEKEIE QLIELANYQV
360 370 380 390 400
LSQQQKSRAF YRIQATRLMT GAGNILKRHA ADQARKAVSM HEVNTEVTEN
410 420 430 440 450
DPVSKIFFEQ GTYQCLENCG TVALTIIRRG GDLTNTVFVD FRTEDGTANA
460 470 480 490 500
GSDYEFTEGT VVFKPGETQK EIRVGIIDDD IFEEDENFLV HLSNVKVSSE
510 520 530 540 550
ASEDGILEAN HVSTLACLGS PSTATVTIFD DDHAGIFTFE EPVTHVSESI
560 570 580 590 600
GIMEVKVLRT SGARGNVIVP YKTIEGTARG GGEDFEDTCG ELEFQNDEIV
610 620 630 640 650
KIITIRIFDR EEYEKECSFS LVLEEPKWIR RGMKGGFTIT DEYDDKQPLT
660 670 680 690 700
SKEEEERRIA EMGRPILGEH TKLEVIIEES YEFKSTVDKL IKKTNLALVV
710 720 730 740 750
GTNSWREQFI EAITVSAGED DDDDECGEEK LPSCFDYVMH FLTVFWKVLF
760 770 780 790 800
AFVPPTEYWN GWACFIVSIL MIGLLTAFIG DLASHFGCTI GLKDSVTAVV
810 820 830 840 850
FVALGTSVPD TFASKVAATQ DQYADASIGN VTGSNAVNVF LGIGVAWSIA
860 870 880 890 900
AIYHAANGEQ FKVSPGTLAF SVTLFTIFAF INVGVLLYRR RPEIGGELGG
910 920 930
PRTAKLLTSC LFVLLWLLYI FFSSLEAYCH IKGF
Length:934
Mass (Da):104,331
Last modified:May 1, 1999 - v1
Checksum:i2A228DA30254BBC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF107593 mRNA Translation: AAD04173.1
RefSeqiNP_001028033.1, NM_001032861.1
XP_014967690.1, XM_015112204.1
XP_014967691.1, XM_015112205.1
XP_014967698.1, XM_015112212.1
UniGeneiMmu.3463

Genome annotation databases

GeneIDi574193
KEGGimcc:574193

Entry informationi

Entry nameiO97801_MACMU
AccessioniPrimary (citable) accession number: O97801
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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