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Protein
Submitted name:

Intercellular adhesion molecule-1

Gene

ICAM-1

Organism
Ovis aries (Sheep)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intercellular adhesion molecule-1Imported
Gene namesi
Name:ICAM-1Imported
OrganismiOvis aries (Sheep)Imported
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei482 – 503HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500416086727 – 530Sequence analysisAdd BLAST504

Structurei

3D structure databases

ProteinModelPortaliO97692.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini394 – 472Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST79

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG052074.
KOiK06490.

Family and domain databases

Gene3Di2.60.40.10. 5 hits.
InterProiIPR003988. ICAM.
IPR013768. ICAM_N.
IPR003987. ICAM_VCAM_N.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
[Graphical view]
PfamiPF03921. ICAM_N. 1 hit.
[Graphical view]
PRINTSiPR01473. ICAM.
PR01472. ICAMVCAM1.
SMARTiSM00409. IG. 3 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O97692-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPGAAPAAL LALLVLLGTL LPGSGGAEIS IHPPKAIIPR GGSLRVNCSI
60 70 80 90 100
SCDRKTTFGL ETVLNKEEVS RGPNWKVFEL SDVQEEINPL CYSNCHGEQI
110 120 130 140 150
VASMNLTIYW FPERVELAPL PLWQPVGEEL NLSCQVSGGG PRHHLSMVLL
160 170 180 190 200
RGEEELDRQP VGKEEPAEVT FMVQPRREDH GTSFSCRWEL DLRSQGLELF
210 220 230 240 250
QNTSAPRKLQ TYVLPSTDPH LEAPPVVEVG SRWPVKCTLD GLFPASDAEV
260 270 280 290 300
YVQLGDQKLE SNITYNGDSV LAEAWTEENE EGTHSLRCSV SLGEKIRRTR
310 320 330 340 350
GSVTMYSFPL PTLTLSPPEV SEWTTVTVEC VTRDGAVVRL NGVSAEPPGP
360 370 380 390 400
RAQLKLNVSA DDHGSNFSCS AALKIAGQEV HKIQTRELHV LYGPRLDQRD
410 420 430 440 450
CLGNWTWQEG SEQTLKCAAR GNPIPKLNCS RKGDGASLPI GDLRPVTREV
460 470 480 490 500
AGTYLCWATS ARGGVTREVV LNVLYGQNIL DIVIPVVAVT LILGTLGTAG
510 520 530
YIYNYQRKIQ KYELQKAQKE AALKLKSTPP
Length:530
Mass (Da):58,030
Last modified:May 1, 1999 - v1
Checksum:iFE49DCC244C941A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF110984 mRNA. Translation: AAD13617.1.
RefSeqiNP_001009731.1. NM_001009731.1.
UniGeneiOar.652.

Genome annotation databases

GeneIDi443045.
KEGGioas:443045.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF110984 mRNA. Translation: AAD13617.1.
RefSeqiNP_001009731.1. NM_001009731.1.
UniGeneiOar.652.

3D structure databases

ProteinModelPortaliO97692.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi443045.
KEGGioas:443045.

Organism-specific databases

CTDi3383.

Phylogenomic databases

HOVERGENiHBG052074.
KOiK06490.

Family and domain databases

Gene3Di2.60.40.10. 5 hits.
InterProiIPR003988. ICAM.
IPR013768. ICAM_N.
IPR003987. ICAM_VCAM_N.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
[Graphical view]
PfamiPF03921. ICAM_N. 1 hit.
[Graphical view]
PRINTSiPR01473. ICAM.
PR01472. ICAMVCAM1.
SMARTiSM00409. IG. 3 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO97692_SHEEP
AccessioniPrimary (citable) accession number: O97692
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: October 5, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.