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Protein
Submitted name:

Cytochrome P450

Gene
N/A
Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3322HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevisibleiO97689. SS.

Structurei

3D structure databases

ProteinModelPortaliO97689.
SMRiO97689. Positions 30-496.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG108567.
KOiK07424.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR008072. Cyt_P450_E_CYP3A.
IPR002402. Cyt_P450_E_grp-II.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00464. EP450II.
PR01689. EP450IICYP3A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O97689-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLIPGFSTE TWVLLATSLV LLYLYGTYSH GLFKKLGIPG PRPLPYFGNI
60 70 80 90 100
LGYRKGVDHF DKKCFQQYGK MWGFFDGRQP VLAITDPDMI KTVLVKECYS
110 120 130 140 150
VFTNRRSFGP RGAMRTALSL AEDEEWKRIR TLLSPTFTSG KLKEMFPIIS
160 170 180 190 200
HYGDLLVSNL RKEAEKGKPV TMKDIFGAYS MDVITSTAFG VNTDFLNNPQ
210 220 230 240 250
DPFVENSKKL LKFSFFSPLF LSIIFFPFLT PILEVLNVTL FPKSVVNFFM
260 270 280 290 300
RSIKRMKESR LKDKQTHRVD FLQLMINSQN SKETDTHKGL SDEELVAQGV
310 320 330 340 350
FFIFAGYETT SSSLSLLVYE LATHPDVQQK LQEEIDATFP SKALPSYDAL
360 370 380 390 400
AQMEYLDMVV NEILRLYPIA ARLERVCKKD VEIHGVSVPK GTVMMVPVFS
410 420 430 440 450
IHRDPELWPE PEEFRPERFS KKNKDSINPY TYLPFGTGPR NCIGMRFALM
460 470 480 490 500
NMKLALVRVL QNFSFKPCKE TQTPLKLSSQ GLIQPEKPIL LKVVPRDGTV

GGA
Length:503
Mass (Da):57,268
Last modified:May 1, 1999 - v1
Checksum:i22DB19F43C5988BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF109068 mRNA. Translation: AAD04628.1.
RefSeqiNP_999587.1. NM_214422.1.
UniGeneiSsc.203.

Genome annotation databases

GeneIDi403322.
KEGGissc:403322.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF109068 mRNA. Translation: AAD04628.1.
RefSeqiNP_999587.1. NM_214422.1.
UniGeneiSsc.203.

3D structure databases

ProteinModelPortaliO97689.
SMRiO97689. Positions 30-496.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi403322.
KEGGissc:403322.

Organism-specific databases

CTDi403322.

Phylogenomic databases

HOVERGENiHBG108567.
KOiK07424.

Gene expression databases

GenevisibleiO97689. SS.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR008072. Cyt_P450_E_CYP3A.
IPR002402. Cyt_P450_E_grp-II.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00464. EP450II.
PR01689. EP450IICYP3A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Porcine Cytochrome-P450 with high protein homology to human CYP3A4 (Nifedipine oxidase J04449)."
    Schuetz E., Andag R., Wieland E., Oellerich M.
    Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO97689_PIG
AccessioniPrimary (citable) accession number: O97689
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: December 9, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.