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Protein
Submitted name:

Fas protein

Gene

Fas

Organism
Ovis aries (Sheep)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Fas proteinImported
Gene namesi
Name:FasImported
OrganismiOvis aries (Sheep)Imported
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500416116023 – 327Sequence analysisAdd BLAST305

Structurei

3D structure databases

ProteinModelPortaliO97491.
SMRiO97491.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini83 – 126TNFR-CysInterPro annotationAdd BLAST44
Repeati83 – 126TNFR-CysPROSITE-ProRule annotationAdd BLAST44
Domaini127 – 164TNFR-CysInterPro annotationAdd BLAST38
Repeati127 – 164TNFR-CysPROSITE-ProRule annotationAdd BLAST38
Domaini242 – 310DeathInterPro annotationAdd BLAST69

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG004091.
KOiK04390.

Family and domain databases

CDDicd08316. Death_FAS_TNFRSF6. 1 hit.
cd10579. TNFRSF6. 1 hit.
InterProiView protein in InterPro
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR008063. Fas_rcpt.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR033998. TNFRSF6_death.
IPR033999. TNFRSF6_N.
PANTHERiPTHR23097:SF158. PTHR23097:SF158. 1 hit.
PfamiView protein in Pfam
PF00531. Death. 1 hit.
PF00020. TNFR_c6. 2 hits.
PRINTSiPR01680. TNFACTORR6.
SMARTiView protein in SMART
SM00005. DEATH. 1 hit.
SM00208. TNFR. 3 hits.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 2 hits.

Sequencei

Sequence statusi: Complete.

O97491-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGIWVHLSL IFISVSRPLS KGENAHVAGI NSEGLRLNKN ITGASSCQEG
60 70 80 90 100
LYREHLFCCQ PCPPGKRKNG DCKRDGDMPE CVLCSEGNEY TDKSHHSDKC
110 120 130 140 150
IRCSVCDEEH GLEVEHNCTR TQNTKCRCKS NFFCNSSPCE HCNPCTTCEH
160 170 180 190 200
GIIEKCTPTS NTKCKGSRSH TNSLWALLIL LLLILIFLII YKVVRRRRRN
210 220 230 240 250
KKNGNCVSAA SSDEGRQLNL TDVDLGKYIP SIAELMKITE VKEFVRKNGM
260 270 280 290 300
EEAKIDDIMH DNLHETAEQK VQLLRKWYQS HGKKNAYCTL TKNLPKALAE
310 320
KICDIVLKDI TNERENANLQ NESENLV
Length:327
Mass (Da):36,928
Last modified:May 1, 1999 - v1
Checksum:i5CFEE844B2BE387A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB011671 mRNA. Translation: BAA37093.1.
RefSeqiNP_001116475.1. NM_001123003.1.
UniGeneiOar.683.

Genome annotation databases

GeneIDi100144426.
KEGGioas:100144426.

Similar proteinsi

Entry informationi

Entry nameiO97491_SHEEP
AccessioniPrimary (citable) accession number: O97491
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: August 30, 2017
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation