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Protein
Submitted name:

Fas protein

Gene

Fas

Organism
Ovis aries (Sheep)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Fas proteinImported
Gene namesi
Name:FasImported
OrganismiOvis aries (Sheep)Imported
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei174 – 19421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 327305Sequence analysisPRO_5004161160Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO97491.
SMRiO97491. Positions 218-327.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini83 – 12644TNFR-CysInterPro annotationAdd
BLAST
Domaini127 – 16438TNFR-CysInterPro annotationAdd
BLAST
Domaini242 – 31069DeathInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG004091.
KOiK04390.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR008063. Fas_rcpt.
IPR001368. TNFR/NGFR_Cys_rich_reg.
[Graphical view]
PANTHERiPTHR23097:SF114. PTHR23097:SF114. 1 hit.
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 2 hits.
[Graphical view]
PRINTSiPR01680. TNFACTORR6.
SMARTiSM00005. DEATH. 1 hit.
SM00208. TNFR. 3 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O97491-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGIWVHLSL IFISVSRPLS KGENAHVAGI NSEGLRLNKN ITGASSCQEG
60 70 80 90 100
LYREHLFCCQ PCPPGKRKNG DCKRDGDMPE CVLCSEGNEY TDKSHHSDKC
110 120 130 140 150
IRCSVCDEEH GLEVEHNCTR TQNTKCRCKS NFFCNSSPCE HCNPCTTCEH
160 170 180 190 200
GIIEKCTPTS NTKCKGSRSH TNSLWALLIL LLLILIFLII YKVVRRRRRN
210 220 230 240 250
KKNGNCVSAA SSDEGRQLNL TDVDLGKYIP SIAELMKITE VKEFVRKNGM
260 270 280 290 300
EEAKIDDIMH DNLHETAEQK VQLLRKWYQS HGKKNAYCTL TKNLPKALAE
310 320
KICDIVLKDI TNERENANLQ NESENLV
Length:327
Mass (Da):36,928
Last modified:May 1, 1999 - v1
Checksum:i5CFEE844B2BE387A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB011671 mRNA. Translation: BAA37093.1.
RefSeqiNP_001116475.1. NM_001123003.1.
UniGeneiOar.683.

Genome annotation databases

GeneIDi100144426.
KEGGioas:100144426.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB011671 mRNA. Translation: BAA37093.1.
RefSeqiNP_001116475.1. NM_001123003.1.
UniGeneiOar.683.

3D structure databases

ProteinModelPortaliO97491.
SMRiO97491. Positions 218-327.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100144426.
KEGGioas:100144426.

Organism-specific databases

CTDi355.

Phylogenomic databases

HOVERGENiHBG004091.
KOiK04390.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR008063. Fas_rcpt.
IPR001368. TNFR/NGFR_Cys_rich_reg.
[Graphical view]
PANTHERiPTHR23097:SF114. PTHR23097:SF114. 1 hit.
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 2 hits.
[Graphical view]
PRINTSiPR01680. TNFACTORR6.
SMARTiSM00005. DEATH. 1 hit.
SM00208. TNFR. 3 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning of sheep fas antigen."
    Takagi M., Takahashi H., Kabeya H., Ohashi K., Sugimoto C., Onuma M.
    Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LymphocyteImported.

Entry informationi

Entry nameiO97491_SHEEP
AccessioniPrimary (citable) accession number: O97491
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: April 13, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.