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Protein
Submitted name:

Ciboulot, isoform A

Gene

cib

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • actin binding Source: FlyBase
  • actin monomer binding Source: FlyBase

GO - Biological processi

  • actin filament organization Source: InterPro
  • brain development Source: FlyBase
  • larval central nervous system remodeling Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ciboulot, isoform AImported
Submitted name:
Ciboulot, isoform BImported
Submitted name:
Ciboulot, isoform DImported
Submitted name:
Ciboulot, isoform EImported
Submitted name:
EG:EG0007.11 proteinImported
Submitted name:
RE50273pImported
Gene namesi
Name:cibImported
Synonyms:EG:EG0007.11Imported
ORF Names:CG4944Imported, Dmel_CG4944Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0026084. cib.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: FlyBase
Complete GO annotation...

Interactioni

GO - Molecular functioni

  • actin binding Source: FlyBase
  • actin monomer binding Source: FlyBase

Protein-protein interaction databases

MINTiMINT-925149.
STRINGi7227.FBpp0070607.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SQKX-ray2.50B10-34[»]
3SJHX-ray1.75B8-29[»]
3U8XX-ray2.00B/D8-29[»]
3U9DX-ray2.50B/D8-24[»]
3U9ZX-ray2.09C2-58[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4794. Eukaryota.
ENOG410Y3I4. LUCA.
GeneTreeiENSGT00530000065074.
OMAiDKSALHH.
OrthoDBiEOG72G187.

Family and domain databases

Gene3Di1.20.5.520. 3 hits.
InterProiIPR001152. Beta-thymosin.
[Graphical view]
PfamiPF01290. Thymosin. 3 hits.
[Graphical view]
ProDomiPD005116. Thymosin_b4. 2 hits.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00152. THY. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O97428-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPAPALKD LPKVAENLKS QLEGFNQDKL KNASTQEKII LPTAEDVAAE
60 70 80 90 100
KTQQSIFEGI TAFNQNNLKH TETNEKNPLP DKEAIEQEKE KNQFIAGIEN
110 120
FDAKKLKHTE TNEKNVLPTK EVIEAEKQA
Length:129
Mass (Da):14,410
Last modified:May 1, 1999 - v1
Checksum:i5D68BE289EC8CE2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF45919.1.
AE014298 Genomic DNA. Translation: AAF45920.1.
AY089633 mRNA. Translation: AAL90371.1.
AE014298 Genomic DNA. Translation: AFH07230.1.
AE014298 Genomic DNA. Translation: AHN59323.1.
AL033125 Genomic DNA. Translation: CAA21832.1.
RefSeqiNP_001245516.1. NM_001258587.1.
NP_001284852.1. NM_001297923.1.
NP_525065.1. NM_080326.4.
NP_726908.1. NM_167001.3.
UniGeneiDm.74.

Genome annotation databases

EnsemblMetazoaiFBtr0070639; FBpp0070607; FBgn0026084.
FBtr0070641; FBpp0070609; FBgn0026084.
FBtr0307206; FBpp0298035; FBgn0026084.
FBtr0343425; FBpp0310070; FBgn0026084.
GeneIDi31359.
KEGGidme:Dmel_CG4944.
UCSCiCG4944-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF45919.1.
AE014298 Genomic DNA. Translation: AAF45920.1.
AY089633 mRNA. Translation: AAL90371.1.
AE014298 Genomic DNA. Translation: AFH07230.1.
AE014298 Genomic DNA. Translation: AHN59323.1.
AL033125 Genomic DNA. Translation: CAA21832.1.
RefSeqiNP_001245516.1. NM_001258587.1.
NP_001284852.1. NM_001297923.1.
NP_525065.1. NM_080326.4.
NP_726908.1. NM_167001.3.
UniGeneiDm.74.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SQKX-ray2.50B10-34[»]
3SJHX-ray1.75B8-29[»]
3U8XX-ray2.00B/D8-29[»]
3U9DX-ray2.50B/D8-24[»]
3U9ZX-ray2.09C2-58[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-925149.
STRINGi7227.FBpp0070607.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0070639; FBpp0070607; FBgn0026084.
FBtr0070641; FBpp0070609; FBgn0026084.
FBtr0307206; FBpp0298035; FBgn0026084.
FBtr0343425; FBpp0310070; FBgn0026084.
GeneIDi31359.
KEGGidme:Dmel_CG4944.
UCSCiCG4944-RA. d. melanogaster.

Organism-specific databases

CTDi31359.
FlyBaseiFBgn0026084. cib.

Phylogenomic databases

eggNOGiKOG4794. Eukaryota.
ENOG410Y3I4. LUCA.
GeneTreeiENSGT00530000065074.
OMAiDKSALHH.
OrthoDBiEOG72G187.

Miscellaneous databases

GenomeRNAii31359.
NextBioi773235.

Family and domain databases

Gene3Di1.20.5.520. 3 hits.
InterProiIPR001152. Beta-thymosin.
[Graphical view]
PfamiPF01290. Thymosin. 3 hits.
[Graphical view]
ProDomiPD005116. Thymosin_b4. 2 hits.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00152. THY. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing the distal X chromosome of Drosophila melanogaster."
    Ferraz C., Vidal S., Brun C., Bucheton A., Demaille J.G.
    Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Benos P.
    Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  5. Cited for: GENOME REANNOTATION.
    Strain: BerkeleyImported.
  6. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  7. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BerkeleyImported.
  9. "The beta-thymosin/WH2 domain; structural basis for the switch from inhibition to promotion of actin assembly."
    Hertzog M., van Heijenoort C., Didry D., Gaudier M., Coutant J., Gigant B., Didelot G., Preat T., Knossow M., Guittet E., Carlier M.F.
    Cell 117:611-623(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 10-34.
  10. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  11. "Drosophila melanogaster release 4 sequence."
    Berkeley Drosophila Genome Project
    Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  12. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  13. O'Boyle S.T.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  14. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  15. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  16. "How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly."
    Didry D., Cantrelle F.X., Husson C., Roblin P., Moorthy A.M., Perez J., Le Clainche C., Hertzog M., Guittet E., Carlier M.F., van Heijenoort C., Renault L.
    EMBO J. 31:1000-1013(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 8-29.
  17. Millard Andrew
    Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO97428_DROME
AccessioniPrimary (citable) accession number: O97428
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: May 11, 2016
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.