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Protein

Integrin beta

Gene

intB

Organism
Suberites domuncula (Sponge)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionIntegrinUniRule annotationSAAS annotationImported
Biological processCell adhesionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Integrin betaUniRule annotation
Gene namesi
Name:intBImported
OrganismiSuberites domuncula (Sponge)Imported
Taxonomic identifieri55567 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPoriferaDemospongiaeHeteroscleromorphaSuberitidaSuberitidaeSuberites

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei696 – 725HelicalSequence analysisAdd BLAST30

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi122 ↔ 129UniRule annotation
Disulfide bondi177 ↔ 218UniRule annotation
Disulfide bondi323 ↔ 332UniRule annotation
Disulfide bondi381 ↔ 385UniRule annotation
Disulfide bondi409 ↔ 418UniRule annotation
Disulfide bondi449 ↔ 454UniRule annotation
Disulfide bondi451 ↔ 486UniRule annotation
Disulfide bondi456 ↔ 471UniRule annotation
Disulfide bondi473 ↔ 478UniRule annotation
Disulfide bondi492 ↔ 497UniRule annotation
Disulfide bondi494 ↔ 532UniRule annotation
Disulfide bondi499 ↔ 514UniRule annotation
Disulfide bondi516 ↔ 522UniRule annotation
Disulfide bondi538 ↔ 544UniRule annotation
Disulfide bondi546 ↔ 555UniRule annotation
Disulfide bondi569 ↔ 578UniRule annotation
Disulfide bondi575 ↔ 687UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO97343.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 383INBInterPro annotationAdd BLAST383
Domaini719 – 764Integrin_b_cytInterPro annotationAdd BLAST46

Sequence similaritiesi

Belongs to the integrin beta chain family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR002369. Integrin_bsu_VWA.
IPR032695. Integrin_dom.
IPR002035. VWF_A.
PANTHERiPTHR10082. PTHR10082. 1 hit.
PfamiView protein in Pfam
PF08725. Integrin_b_cyt. 1 hit.
PF00362. Integrin_beta. 1 hit.
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiView protein in SMART
SM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
PROSITEiView protein in PROSITE
PS00243. INTEGRIN_BETA. 1 hit.

Sequencei

Sequence statusi: Complete.

O97343-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLQPSIRPA PMGGSSNTAS PPLEGNTQIS PSIVRVDIRP GQPVNFPITV
60 70 80 90 100
RPARNFPGDI YLLMDLSFSM ADDLQNLKNL GSRLATEISG ISENFQVGFG
110 120 130 140 150
SFVDKRLPPF VSLDPVRQNN PCPGTDPPCV STYSFRHSVK LTDNDVFFNQ
160 170 180 190 200
QVQDQMISGN QDSPEGGFDG FLQPIVCTNL IGWRDVSRKL LLYITDAGFH
210 220 230 240 250
IAGDGKVAGV ILPNDGTCRT SGTTAPQDYD DWITYDYPSI GQIAQALREN
260 270 280 290 300
DIIPIFAAEA RALPVYEALV REIGEGAFSG TLARDSGNIV DLVRESYNNV
310 320 330 340 350
SQRIIFGPER VPGVSVDIQP TNCPGEIVDG VCTGVQIENN ATFQVSVTLQ
360 370 380 390 400
ECTPENSGNI VTVPIRVLGF GSFDIELNAI CSCPCDGTVT NNSALCTGNG
410 420 430 440 450
TLRCGQCDCN PGRFGDMCQC DATGQGGMQQ MCPLGPTELQ CTSTDRGTCV
460 470 480 490 500
CGECQCRRDS AGNPIYFGPA CECDRSSCPS FNGELCAGRG ACTCDGCRCN
510 520 530 540 550
LEPNTQQPYF GTACECSPDT NCVDPNNSTD ICNGRGTCGC SGRCDCQFPY
560 570 580 590 600
RGDFCEVCSG DESCFDLTCD SNAECANCAV DILDLFPMST NLTFFTNETL
610 620 630 640 650
NSLPNGTSLT YDALSNTFRL RLPTGECPET CSPVVIINGT DDVDYMIQDE
660 670 680 690 700
MSIRCELVRG CTYRYYVAVN EDTLDLTDVH VEFRRFCPEP VIQTPAWIIA
710 720 730 740 750
IAIIVALLIL GVIALLLLKL FLFIIDVIEV KKFEKELAKT KYPKHQNPLY
760
RSAAKDYQNP IYGQ
Length:764
Mass (Da):83,005
Last modified:May 1, 1999 - v1
Checksum:iAF12FAD0E2FA0188
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y18468 mRNA. Translation: CAB38100.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO97343_SUBDO
AccessioniPrimary (citable) accession number: O97343
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: July 5, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)